{"id":"https://openalex.org/W2071748249","doi":"https://doi.org/10.1016/j.expneurol.2010.12.004","title":"Chronic dizocilpine or apomorphine and development of neuropathy in two rat models I: Behavioral effects and role of nucleus accumbens","display_name":"Chronic dizocilpine or apomorphine and development of neuropathy in two rat models I: Behavioral effects and role of nucleus accumbens","publication_year":2010,"publication_date":"2010-12-12","ids":{"openalex":"https://openalex.org/W2071748249","doi":"https://doi.org/10.1016/j.expneurol.2010.12.004","mag":"2071748249","pmid":"https://pubmed.ncbi.nlm.nih.gov/21146525"},"language":"en","primary_location":{"id":"doi:10.1016/j.expneurol.2010.12.004","doi":"https://doi.org/10.1016/j.expneurol.2010.12.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.expneurol.2010.12.004","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035748074","display_name":"Rani A. Sarkis","orcid":"https://orcid.org/0000-0001-8291-7864","observed_orcids":["https://orcid.org/0000-0001-8291-7864"]},"institutions":[{"id":"https://openalex.org/I98635879","display_name":"American University of Beirut","ror":"https://ror.org/04pznsd21","country_code":"LB","type":"education","lineage":["https://openalex.org/I98635879"]}],"countries":["LB"],"is_corresponding":false,"raw_author_name":"Rani Sarkis","raw_affiliation_strings":["Department of Physiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","institution_ids":["https://openalex.org/I98635879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005945559","display_name":"Nayef E. Saad\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98635879","display_name":"American University of Beirut","ror":"https://ror.org/04pznsd21","country_code":"LB","type":"education","lineage":["https://openalex.org/I98635879"]}],"countries":["LB"],"is_corresponding":false,"raw_author_name":"Nayef Saad\u00e9","raw_affiliation_strings":["Department of Human Morphology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","Department of Physiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Morphology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","institution_ids":["https://openalex.org/I98635879"]},{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","institution_ids":["https://openalex.org/I98635879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062329273","display_name":"Samir Atweh","orcid":"https://orcid.org/0000-0003-0611-0924","observed_orcids":["https://orcid.org/0000-0003-0611-0924"]},"institutions":[{"id":"https://openalex.org/I98635879","display_name":"American University of Beirut","ror":"https://ror.org/04pznsd21","country_code":"LB","type":"education","lineage":["https://openalex.org/I98635879"]}],"countries":["LB"],"is_corresponding":false,"raw_author_name":"Samir Atweh","raw_affiliation_strings":["Department of Internal Medicine, Faculty of Medicine, American University of Beirut, Beirut, Lebanon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","institution_ids":["https://openalex.org/I98635879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011946638","display_name":"Suhayl J. Jabbur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98635879","display_name":"American University of Beirut","ror":"https://ror.org/04pznsd21","country_code":"LB","type":"education","lineage":["https://openalex.org/I98635879"]}],"countries":["LB"],"is_corresponding":false,"raw_author_name":"Suhayl Jabbur","raw_affiliation_strings":["Department of Physiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","institution_ids":["https://openalex.org/I98635879"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026063267","display_name":"Hassen A. Al-Amin","orcid":"https://orcid.org/0000-0001-6358-1541","observed_orcids":["https://orcid.org/0000-0001-6358-1541"]},"institutions":[{"id":"https://openalex.org/I98635879","display_name":"American University of Beirut","ror":"https://ror.org/04pznsd21","country_code":"LB","type":"education","lineage":["https://openalex.org/I98635879"]}],"countries":["LB"],"is_corresponding":true,"raw_author_name":"Hassen Al-Amin","raw_affiliation_strings":["Department of Psychiatry, Faculty of Medicine, American University of Beirut, Beirut, Lebanon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Faculty of Medicine, American University of Beirut, Beirut, Lebanon","institution_ids":["https://openalex.org/I98635879"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026063267"],"corresponding_institution_ids":["https://openalex.org/I98635879"],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":null,"fwci":1.2191,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.78144834,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"228","issue":"1","first_page":"19","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.906000018119812},{"id":"https://openalex.org/keywords/nucleus-accumbens","display_name":"nucleus accumbens","score":0.8610000014305115},{"id":"https://openalex.org/keywords/mk-801","display_name":"MK-801","score":0.9599999785423279},{"id":"https://openalex.org/keywords/nmda-receptor-antagonism","display_name":"NMDA receptor antagonism","score":0.8050000071525574},{"id":"https://openalex.org/keywords/apomorphine","display_name":"apomorphine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.8389999866485596},{"id":"https://openalex.org/keywords/chronic-constriction-injury","display_name":"chronic constriction injury","score":0.9829999804496765},{"id":"https://openalex.org/keywords/spared-nerve-injury","display_name":"spared nerve injury","score":0.996999979019165},{"id":"https://openalex.org/keywords/allodynia","display_name":"allodynia","score":0.8159999847412109},{"id":"https://openalex.org/keywords/thermal-hyperalgesia","display_name":"thermal hyperalgesia","score":0.9070000052452087},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.6520000100135803},{"id":"https://openalex.org/keywords/mononeuropathy","display_name":"mononeuropathy","score":0.7200000286102295},{"id":"https://openalex.org/keywords/pain-modulation","display_name":"pain modulation","score":0.44600000977516174}],"concepts":[{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.7977992296218872},{"id":"https://openalex.org/C2777836312","wikidata":"https://www.wikidata.org/wiki/Q4386371","display_name":"Dizocilpine","level":4,"score":0.6946266293525696},{"id":"https://openalex.org/C2776552330","wikidata":"https://www.wikidata.org/wiki/Q1476178","display_name":"Nucleus accumbens","level":3,"score":0.6795262694358826},{"id":"https://openalex.org/C90149880","wikidata":"https://www.wikidata.org/wiki/Q1092165","display_name":"SNi","level":4,"score":0.6372162103652954},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6282387971878052},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.603672206401825},{"id":"https://openalex.org/C2777883359","wikidata":"https://www.wikidata.org/wiki/Q1888634","display_name":"Allodynia","level":5,"score":0.5945360660552979},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.5699672102928162},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5171260833740234},{"id":"https://openalex.org/C2775991916","wikidata":"https://www.wikidata.org/wiki/Q2945973","display_name":"Nerve injury","level":2,"score":0.4929375648498535},{"id":"https://openalex.org/C2777525119","wikidata":"https://www.wikidata.org/wiki/Q269111","display_name":"Apomorphine","level":4,"score":0.4424078166484833},{"id":"https://openalex.org/C2779245659","wikidata":"https://www.wikidata.org/wiki/Q1633866","display_name":"Hyperalgesia","level":4,"score":0.4285764694213867},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.40786904096603394},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30755436420440674},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.29474973678588867},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.28166159987449646},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.2730732262134552},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1318565011024475},{"id":"https://openalex.org/C16993767","wikidata":"https://www.wikidata.org/wiki/Q4674072","display_name":"Acid hydrolysis","level":3,"score":0.0},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001058","descriptor_name":"Apomorphine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009437","descriptor_name":"Neuralgia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009437","descriptor_name":"Neuralgia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009437","descriptor_name":"Neuralgia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D009714","descriptor_name":"Nucleus Accumbens","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009714","descriptor_name":"Nucleus Accumbens","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016291","descriptor_name":"Dizocilpine Maleate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020422","descriptor_name":"Mononeuropathies","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020422","descriptor_name":"Mononeuropathies","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.expneurol.2010.12.004","doi":"https://doi.org/10.1016/j.expneurol.2010.12.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.expneurol.2010.12.004","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},{"id":"pmid:21146525","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21146525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental neurology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320324215","display_name":"Conseil National de la Recherche Scientifique","ror":"https://ror.org/00x9ewr78"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W249845531","https://openalex.org/W1575571855","https://openalex.org/W1580154066","https://openalex.org/W1896149175","https://openalex.org/W1963519570","https://openalex.org/W1964600015","https://openalex.org/W1965538993","https://openalex.org/W1965981384","https://openalex.org/W1976267456","https://openalex.org/W1978381097","https://openalex.org/W1982613499","https://openalex.org/W1985021707","https://openalex.org/W1989188733","https://openalex.org/W1989804049","https://openalex.org/W1992263281","https://openalex.org/W1994305836","https://openalex.org/W1998126770","https://openalex.org/W2000492372","https://openalex.org/W2003283695","https://openalex.org/W2003628930","https://openalex.org/W2011894583","https://openalex.org/W2014007136","https://openalex.org/W2019766484","https://openalex.org/W2021399976","https://openalex.org/W2021489201","https://openalex.org/W2026527037","https://openalex.org/W2027278658","https://openalex.org/W2037789276","https://openalex.org/W2044239788","https://openalex.org/W2044860425","https://openalex.org/W2045274602","https://openalex.org/W2045798386","https://openalex.org/W2047010161","https://openalex.org/W2051597690","https://openalex.org/W2057749702","https://openalex.org/W2058020736","https://openalex.org/W2060370855","https://openalex.org/W2065296100","https://openalex.org/W2066266944","https://openalex.org/W2069132416","https://openalex.org/W2071334120","https://openalex.org/W2077144344","https://openalex.org/W2084424517","https://openalex.org/W2084631926","https://openalex.org/W2087454739","https://openalex.org/W2090592426","https://openalex.org/W2091084541","https://openalex.org/W2095136128","https://openalex.org/W2119155925","https://openalex.org/W2157034806","https://openalex.org/W2163815564","https://openalex.org/W2385302703","https://openalex.org/W4231837856","https://openalex.org/W6710752967"],"related_works":["https://openalex.org/W2027278658","https://openalex.org/W1992263281","https://openalex.org/W2258450307","https://openalex.org/W4205551180","https://openalex.org/W2790155288","https://openalex.org/W2248616108","https://openalex.org/W1974512593","https://openalex.org/W2091376544","https://openalex.org/W2146461945","https://openalex.org/W2019766484"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}