{"id":"https://openalex.org/W2071258005","doi":"https://doi.org/10.1016/s1383-5718(02)00018-9","title":"A combination of the micronucleus assay and a FISH technique for evaluation of the genotoxicity of 1,2,4-benzenetriol","display_name":"A combination of the micronucleus assay and a FISH technique for evaluation of the genotoxicity of 1,2,4-benzenetriol","publication_year":2002,"publication_date":"2002-04-01","ids":{"openalex":"https://openalex.org/W2071258005","doi":"https://doi.org/10.1016/s1383-5718(02)00018-9","mag":"2071258005","pmid":"https://pubmed.ncbi.nlm.nih.gov/11943610"},"language":"en","primary_location":{"id":"doi:10.1016/s1383-5718(02)00018-9","doi":"https://doi.org/10.1016/s1383-5718(02)00018-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1383-5718(02)00018-9","pdf_url":null,"source":{"id":"https://openalex.org/S29775604","display_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","issn_l":"1383-5718","issn":["1383-5718","1879-3592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102104917","display_name":"Hai Won Chung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hai Won Chung","raw_affiliation_strings":["School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, 110-460, South Korea. chunghw@snu.ac.kr","School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, Seoul 110-460, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, 110-460, South Korea. chunghw@snu.ac.kr","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, Seoul 110-460, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102015973","display_name":"Su Jin Kang","orcid":"https://orcid.org/0000-0002-0369-2175","observed_orcids":["https://orcid.org/0000-0002-0369-2175","https://orcid.org/0000-0002-4876-3205"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Su Jin Kang","raw_affiliation_strings":["School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, Seoul 110-460, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, Seoul 110-460, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100645032","display_name":"Su Young Kim","orcid":"https://orcid.org/0000-0002-6486-8445","observed_orcids":["https://orcid.org/0000-0002-6486-8445","https://orcid.org/0000-0001-7190-0362"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Su Young Kim","raw_affiliation_strings":["School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, Seoul 110-460, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, Seoul National University, 28 Yunkeun-dong, Chongno-ku, Seoul 110-460, South Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5102104917"],"corresponding_institution_ids":["https://openalex.org/I139264467"],"apc_list":{"value":3350,"currency":"USD","value_usd":3350},"apc_paid":null,"fwci":1.3168,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.79066157,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"516","issue":"1-2","first_page":"49","last_page":"56"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/1-2-4-benzenetriol","display_name":"1,2,4-benzenetriol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cytokinesis-block-micronucleus-assay","display_name":"cytokinesis-block micronucleus assay","score":0.8399999737739563},{"id":"https://openalex.org/keywords/fluorescence-in-situ-hybridization","display_name":"fluorescence in situ hybridization","score":0.9779999852180481},{"id":"https://openalex.org/keywords/centromeric-probes","display_name":"centromeric probes","score":0.8610000014305115},{"id":"https://openalex.org/keywords/chromosome-7","display_name":"chromosome 7","score":0.7749999761581421},{"id":"https://openalex.org/keywords/chromosome-8","display_name":"chromosome 8","score":1.0},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.9800000190734863},{"id":"https://openalex.org/keywords/clastogens","display_name":"clastogens","score":0.656000018119812},{"id":"https://openalex.org/keywords/aneugens","display_name":"aneugens","score":0.8880000114440918},{"id":"https://openalex.org/keywords/human-lymphocytes","display_name":"human lymphocytes","score":0.8629999756813049},{"id":"https://openalex.org/keywords/benzene-metabolites","display_name":"benzene metabolites","score":0.8650000095367432},{"id":"https://openalex.org/keywords/chromosomal-damage","display_name":"chromosomal damage","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.8451030254364014},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.7734986543655396},{"id":"https://openalex.org/C63491729","wikidata":"https://www.wikidata.org/wiki/Q14762596","display_name":"Centromere","level":4,"score":0.6982253789901733},{"id":"https://openalex.org/C36681516","wikidata":"https://www.wikidata.org/wiki/Q1700733","display_name":"Micronucleus","level":4,"score":0.6867308616638184},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6389877200126648},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.623883843421936},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5671194791793823},{"id":"https://openalex.org/C143016879","wikidata":"https://www.wikidata.org/wiki/Q4914552","display_name":"Binucleated cells","level":5,"score":0.5304175019264221},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.5170103311538696},{"id":"https://openalex.org/C2777542201","wikidata":"https://www.wikidata.org/wiki/Q1336182","display_name":"Fluorescence in situ hybridization","level":4,"score":0.4703626334667206},{"id":"https://openalex.org/C2994296024","wikidata":"https://www.wikidata.org/wiki/Q744962","display_name":"Chromosome aberration","level":4,"score":0.4292541444301605},{"id":"https://openalex.org/C2778959862","wikidata":"https://www.wikidata.org/wiki/Q1009245","display_name":"Genotoxicity","level":3,"score":0.41825294494628906},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3704667091369629},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.23876646161079407},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14995431900024414},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000782","descriptor_name":"Aneuploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002503","descriptor_name":"Centromere","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002897","descriptor_name":"Chromosomes, Human, Pair 7","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002898","descriptor_name":"Chromosomes, Human, Pair 8","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006873","descriptor_name":"Hydroquinones","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009152","descriptor_name":"Mutagenicity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015162","descriptor_name":"Micronucleus Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015342","descriptor_name":"DNA Probes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048629","descriptor_name":"Micronuclei, Chromosome-Defective","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1383-5718(02)00018-9","doi":"https://doi.org/10.1016/s1383-5718(02)00018-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1383-5718(02)00018-9","pdf_url":null,"source":{"id":"https://openalex.org/S29775604","display_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","issn_l":"1383-5718","issn":["1383-5718","1879-3592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","raw_type":"journal-article"},{"id":"pmid:11943610","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11943610","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Evaluation Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":0.8199999928474426}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1968724853","https://openalex.org/W1971162072","https://openalex.org/W1974918432","https://openalex.org/W1981489396","https://openalex.org/W1983263107","https://openalex.org/W1983785443","https://openalex.org/W2013775348","https://openalex.org/W2018601241","https://openalex.org/W2040635823","https://openalex.org/W2041227927","https://openalex.org/W2047345111","https://openalex.org/W2056204961","https://openalex.org/W2057140174","https://openalex.org/W2057853942","https://openalex.org/W2066856430","https://openalex.org/W2082232487","https://openalex.org/W2094480029","https://openalex.org/W2119447976","https://openalex.org/W2130621205","https://openalex.org/W2133939418","https://openalex.org/W2137115030","https://openalex.org/W2167674158","https://openalex.org/W2346419124","https://openalex.org/W6679941510"],"related_works":["https://openalex.org/W2482799244","https://openalex.org/W4410736155","https://openalex.org/W191375967","https://openalex.org/W2148914308","https://openalex.org/W3002624529","https://openalex.org/W47152914","https://openalex.org/W2018112799","https://openalex.org/W2125871939","https://openalex.org/W2117100452","https://openalex.org/W2024264346"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}