{"id":"https://openalex.org/W2071202804","doi":"https://doi.org/10.1177/1049909113494002","title":"Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device","display_name":"Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device","publication_year":2013,"publication_date":"2013-07-08","ids":{"openalex":"https://openalex.org/W2071202804","doi":"https://doi.org/10.1177/1049909113494002","mag":"2071202804","pmid":"https://pubmed.ncbi.nlm.nih.gov/23838448"},"language":"en","primary_location":{"id":"doi:10.1177/1049909113494002","doi":"https://doi.org/10.1177/1049909113494002","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1049909113494002","pdf_url":null,"source":{"id":"https://openalex.org/S92692057","display_name":"American Journal of Hospice and Palliative Medicine\u00ae","issn_l":"1049-9091","issn":["1049-9091","1938-2715"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Hospice and Palliative Medicine\u00ae","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054848999","display_name":"Thomas J. Smith","orcid":"https://orcid.org/0000-0003-3040-6434","observed_orcids":["https://orcid.org/0000-0003-3040-6434"]},"institutions":[{"id":"https://openalex.org/I4210164401","display_name":"Sidney Kimmel Comprehensive Cancer Center","ror":"https://ror.org/05m5b8x20","country_code":"US","type":"facility","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Thomas J. Smith","raw_affiliation_strings":["Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA","1 Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA","institution_ids":["https://openalex.org/I4210164401"]},{"raw_affiliation_string":"1 Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA","institution_ids":["https://openalex.org/I4210164401"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087748917","display_name":"Giuseppe Marineo","orcid":"https://orcid.org/0000-0002-5685-7607","observed_orcids":["https://orcid.org/0000-0002-5685-7607"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Marineo","raw_affiliation_strings":["Delta Research & Development, University of Rome Tor Vergata, Rome, Italy","2 Delta Research & Development, University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Delta Research & Development, University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]},{"raw_affiliation_string":"2 Delta Research & Development, University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5054848999"],"corresponding_institution_ids":["https://openalex.org/I4210164401"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":2.965,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.90490327,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"35","issue":"5","first_page":"812","last_page":"813"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postherpetic-neuralgia","display_name":"postherpetic neuralgia","score":0.9070000052452087},{"id":"https://openalex.org/keywords/scrambler-therapy","display_name":"scrambler therapy","score":0.8299999833106995},{"id":"https://openalex.org/keywords/refractory-pain","display_name":"refractory pain","score":0.8799999952316284},{"id":"https://openalex.org/keywords/pain-relief","display_name":"analgesia","score":0.7620000243186951},{"id":"https://openalex.org/keywords/surface-electrodes","display_name":"surface electrodes","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C2778866549","wikidata":"https://www.wikidata.org/wiki/Q1714245","display_name":"Postherpetic neuralgia","level":3,"score":0.7615417838096619},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6059167385101318},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5765208005905151},{"id":"https://openalex.org/C2909941344","wikidata":"https://www.wikidata.org/wiki/Q1752305","display_name":"Electric stimulation therapy","level":3,"score":0.45732346177101135},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.342154324054718},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.29362401366233826},{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.21317636966705322},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06898340582847595}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004599","descriptor_name":"Electric Stimulation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051474","descriptor_name":"Neuralgia, Postherpetic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D059408","descriptor_name":"Pain Management","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/1049909113494002","doi":"https://doi.org/10.1177/1049909113494002","is_oa":false,"landing_page_url":"https://doi.org/10.1177/1049909113494002","pdf_url":null,"source":{"id":"https://openalex.org/S92692057","display_name":"American Journal of Hospice and Palliative Medicine\u00ae","issn_l":"1049-9091","issn":["1049-9091","1938-2715"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Hospice and Palliative Medicine\u00ae","raw_type":"journal-article"},{"id":"pmid:23838448","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23838448","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of hospice & palliative care","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.800000011920929,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1943094646","https://openalex.org/W1966600932","https://openalex.org/W2009379461","https://openalex.org/W2021717663","https://openalex.org/W2064412907","https://openalex.org/W2113680685","https://openalex.org/W2118453217","https://openalex.org/W2129133048","https://openalex.org/W2129390808","https://openalex.org/W2131041950","https://openalex.org/W2138676765","https://openalex.org/W2148049464","https://openalex.org/W2599107004"],"related_works":["https://openalex.org/W2151870637","https://openalex.org/W2118453217","https://openalex.org/W7216531646","https://openalex.org/W1950671387","https://openalex.org/W2317448604","https://openalex.org/W2028119812","https://openalex.org/W2129133048","https://openalex.org/W3205009173","https://openalex.org/W4220880671","https://openalex.org/W2979606626"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Postherpetic":[1],"neuropathy":[2],"(PHN)":[3],"is":[4,117],"common,":[5],"severe,":[6],"and":[7,49,82,108,111],"often":[8],"refractory":[9,17],"to":[10,67,99],"treatment.":[11,51],"We":[12],"treated":[13],"10":[14,43],"patients":[15],"with":[16,30,77,90,106],"PHN":[18],"using":[19],"Scrambler":[20,34,96],"therapy,":[21],"a":[22,74,101],"neurocutaneous":[23],"stimulation":[24],"device":[25],"that":[26],"delivers":[27],"\"nonpain\"":[28],"information":[29],"surface":[31],"electrodes.":[32],"METHODS:":[33],"therapy":[35,97],"was":[36,46],"given":[37],"as":[38],"30-minute":[39],"sessions":[40],"daily":[41],"for":[42],"days.":[44],"Pain":[45],"recorded":[47],"before":[48],"after":[50],"Two":[52],"centers.":[53],"RESULT:":[54],"The":[55],"average":[56],"pain":[57,88],"score":[58],"rapidly":[59],"diminished":[60],"from":[61],"7.64":[62],"\u00b1":[63,69],"1.46":[64],"at":[65,71,80],"baseline":[66],"0.42":[68],"0.89":[70],"1":[72],"month,":[73],"95%":[75],"reduction,":[76],"continued":[78,109],"relief":[79,89,110],"2":[81],"3":[83],"months.":[84],"Patients":[85],"achieved":[86],"maximum":[87],"less":[91],"than":[92],"5":[93],"treatments.":[94],"DISCUSSION:":[95],"appears":[98],"have":[100],"promising":[102],"effect":[103],"on":[104],"PHN,":[105],"prompt":[107],"no":[112],"side":[113],"effects.":[114],"Further":[115],"research":[116],"warranted.":[118]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}