{"id":"https://openalex.org/W2071094537","doi":"https://doi.org/10.2147/hiv.s73880","title":"Anal high-risk human papillomavirus infection and high-grade anal intraepithelial neoplasia detected in women and heterosexual men infected with human immunodeficiency virus","display_name":"Anal high-risk human papillomavirus infection and high-grade anal intraepithelial neoplasia detected in women and heterosexual men infected with human immunodeficiency virus","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2071094537","doi":"https://doi.org/10.2147/hiv.s73880","mag":"2071094537","pmid":"https://pubmed.ncbi.nlm.nih.gov/25670914","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4315557"},"language":"en","primary_location":{"id":"doi:10.2147/hiv.s73880","doi":"https://doi.org/10.2147/hiv.s73880","is_oa":true,"landing_page_url":"https://doi.org/10.2147/hiv.s73880","pdf_url":"https://www.dovepress.com/getfile.php?fileID=23417","source":{"id":"https://openalex.org/S2739411477","display_name":"HIV/AIDS - Research and Palliative Care","issn_l":"1179-1373","issn":["1179-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV/AIDS - Research and Palliative Care","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=23417","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043604931","display_name":"Sumanth Gandra","orcid":"https://orcid.org/0000-0003-1482-0854","observed_orcids":["https://orcid.org/0000-0003-1482-0854"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sumanth Gandra","raw_affiliation_strings":["Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044638082","display_name":"Aline Azar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aline Azar","raw_affiliation_strings":["Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007873527","display_name":"Mireya Wessolossky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mireya Wessolossky","raw_affiliation_strings":["Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USA","institution_ids":["https://openalex.org/I166722992"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043604931"],"corresponding_institution_ids":["https://openalex.org/I166722992"],"apc_list":{"value":2320,"currency":"USD","value_usd":2320},"apc_paid":{"value":2320,"currency":"USD","value_usd":2320},"fwci":2.0083,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.85191244,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"7","issue":null,"first_page":"29","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13110","display_name":"Colorectal and Anal Carcinomas","score":0.01080000028014183,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-risk-hpv","display_name":"high-risk HPV","score":0.9100000262260437},{"id":"https://openalex.org/keywords/anal-intraepithelial-neoplasia","display_name":"anal intraepithelial neoplasia","score":0.9300000071525574},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.8650000095367432},{"id":"https://openalex.org/keywords/anal-cancer-screening","display_name":"anal cancer screening","score":0.9490000009536743},{"id":"https://openalex.org/keywords/anal-cytology","display_name":"anal cytology","score":0.9789999723434448},{"id":"https://openalex.org/keywords/men-who-have-sex-with-men","display_name":"men who have sex with men","score":0.8849999904632568},{"id":"https://openalex.org/keywords/heterosexual-men","display_name":"heterosexual men","score":0.9760000109672546},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.925000011920929},{"id":"https://openalex.org/keywords/high-resolution-anoscopy","display_name":"high-resolution anoscopy","score":0.6499999761581421},{"id":"https://openalex.org/keywords/ascus","display_name":"ASCUS","score":0.7979999780654907},{"id":"https://openalex.org/keywords/screening-test-performance","display_name":"screening test performance","score":0.5019999742507935}],"concepts":[{"id":"https://openalex.org/C2994532551","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"Human papillomavirus","level":2,"score":0.7137526273727417},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5595429539680481},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5467400550842285},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4251050055027008},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07193630933761597}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.2147/hiv.s73880","doi":"https://doi.org/10.2147/hiv.s73880","is_oa":true,"landing_page_url":"https://doi.org/10.2147/hiv.s73880","pdf_url":"https://www.dovepress.com/getfile.php?fileID=23417","source":{"id":"https://openalex.org/S2739411477","display_name":"HIV/AIDS - Research and Palliative Care","issn_l":"1179-1373","issn":["1179-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV/AIDS - Research and Palliative Care","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3288899","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4315557","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:25670914","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25670914","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV/AIDS (Auckland, N.Z.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4315557","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4315557/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV AIDS (Auckl)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:084eb38c5f58417b898a18b728e0a94e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/084eb38c5f58417b898a18b728e0a94e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HIV/AIDS: Research and Palliative Care, Vol 2015, Iss default, Pp 29-34 (2015)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/20134","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/anal-high-risk-human-papillomavirus-infection-and-high-grade-anal-intr-peer-reviewed-article-HIV","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/hiv.s73880","doi":"https://doi.org/10.2147/hiv.s73880","is_oa":true,"landing_page_url":"https://doi.org/10.2147/hiv.s73880","pdf_url":"https://www.dovepress.com/getfile.php?fileID=23417","source":{"id":"https://openalex.org/S2739411477","display_name":"HIV/AIDS - Research and Palliative Care","issn_l":"1179-1373","issn":["1179-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV/AIDS - Research and Palliative Care","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2071094537.pdf","grobid_xml":"https://content.openalex.org/works/W2071094537.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W316269977","https://openalex.org/W1507980006","https://openalex.org/W1975077072","https://openalex.org/W1980232629","https://openalex.org/W2019037399","https://openalex.org/W2020917165","https://openalex.org/W2037977447","https://openalex.org/W2041176483","https://openalex.org/W2045986885","https://openalex.org/W2056931970","https://openalex.org/W2062585327","https://openalex.org/W2068260090","https://openalex.org/W2078150697","https://openalex.org/W2079293207","https://openalex.org/W2100850098","https://openalex.org/W2106993950","https://openalex.org/W2122165542","https://openalex.org/W2123446680","https://openalex.org/W2123846636","https://openalex.org/W2124582318","https://openalex.org/W2128247901","https://openalex.org/W2128505644","https://openalex.org/W2132065842","https://openalex.org/W2133765716","https://openalex.org/W2136486563","https://openalex.org/W2168383265","https://openalex.org/W2324299759"],"related_works":["https://openalex.org/W1976253385","https://openalex.org/W2020917165","https://openalex.org/W2736847213","https://openalex.org/W2168292562","https://openalex.org/W1902900444","https://openalex.org/W1442855787","https://openalex.org/W3023677434","https://openalex.org/W2143167815","https://openalex.org/W2624497995","https://openalex.org/W2065328821"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"anal":[2,9,49,62,90,94,116,126,133,141,192,226,241],"high-risk":[3],"human":[4,16],"papillomavirus":[5],"(HR-HPV)":[6],"infection":[7],"and":[8,39,53,72,75,96,115,138,182,205,223],"cytological":[10,51],"abnormalities":[11,33],"are":[12,28],"highly":[13],"prevalent":[14],"among":[15,34,66,244],"immunodeficiency":[17],"virus":[18],"(HIV)-infected":[19],"men":[20,25,37],"who":[21,88],"have":[22],"sex":[23],"with":[24,85,93,150,188,191],"(MSM),":[26],"there":[27],"insufficient":[29],"data":[30],"on":[31,194],"these":[32,56,171],"HIV-infected":[35,70,86,110,221,231],"heterosexual":[36],"(HSM)":[38],"women.":[40,145],"In":[41],"this":[42],"study,":[43],"we":[44],"evaluated":[45],"the":[46,119,215],"prevalence":[47],"of":[48,55,69,108,121,129,136,144,160,217],"HR-HPV,":[50],"abnormalities,":[52],"performance":[54],"screening":[57,92,228,243],"tests":[58],"in":[59,123,196,219,229],"detecting":[60],"high-grade":[61],"intraepithelial":[63],"neoplasia":[64],"(AIN2+)":[65],"our":[67],"cohort":[68,81],"MSM":[71,198],"non-MSM":[73,206],"(HSM":[74],"women).":[76],"METHODS:":[77],"A":[78],"single-center,":[79],"retrospective":[80],"study":[82],"was":[83,156],"conducted":[84],"individuals":[87,111,149,175,232],"underwent":[89,166],"cancer":[91,227,242],"cytology":[95,117,127,134,142,155,193],"HR-HPV":[97,114,122,185,236],"testing":[98],"from":[99],"January":[100,103],"2011":[101],"to":[102],"31,":[104],"2013.":[105],"RESULTS:":[106],"Screening":[107],"221":[109],"for":[112,240],"both":[113,197],"showed":[118],"presence":[120,216],"54%":[124],"(abnormal":[125,132,140],"48%)":[128],"MSM,":[130,179],"28%":[131],"28%)":[135],"HSM,":[137],"27%":[139],"34%)":[143],"Among":[146],"117":[147],"(53%)":[148],"abnormal":[151],"results":[152],"(HR-HPV-positive":[153],"and/or":[154],"atypical":[157],"squamous":[158],"cells":[159],"undetermined":[161],"significance":[162],"or":[163],"above),":[164],"67":[165,172],"high":[167],"resolution":[168],"anoscopy.":[169],"Of":[170],"individuals,":[173],"22":[174],"had":[176],"AIN2+":[177,189,218],"(17":[178],"four":[180],"women,":[181,224],"one":[183],"HSM).":[184],"correlated":[186],"better":[187],"than":[190],"biopsy":[195],"(r=0.29":[199],"versus":[200,203,208,211],"r=0.10;":[201],"P=0.05":[202],"P=0.49)":[204],"(r=0.36":[207],"r=-0.34;":[209],"P=0.08":[210],"P=0.09).":[212],"CONCLUSION:":[213],"Given":[214],"screened":[220],"HSM":[222],"routine":[225],"all":[230],"should":[233],"be":[234],"considered.":[235],"merits":[237],"further":[238],"evaluation":[239],"non-MSM.":[245]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}