{"id":"https://openalex.org/W2071069499","doi":"https://doi.org/10.1007/s00441-002-0541-z","title":"Phenotypic characteristics of adipocytes generated from Meckel's chondrocytes in response to chick serum in vitro","display_name":"Phenotypic characteristics of adipocytes generated from Meckel's chondrocytes in response to chick serum in vitro","publication_year":2002,"publication_date":"2002-08-01","ids":{"openalex":"https://openalex.org/W2071069499","doi":"https://doi.org/10.1007/s00441-002-0541-z","mag":"2071069499","pmid":"https://pubmed.ncbi.nlm.nih.gov/12172784"},"language":"en","primary_location":{"id":"doi:10.1007/s00441-002-0541-z","doi":"https://doi.org/10.1007/s00441-002-0541-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00441-002-0541-z","pdf_url":null,"source":{"id":"https://openalex.org/S139399906","display_name":"Cell and Tissue Research","issn_l":"0302-766X","issn":["0302-766X","1432-0878"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell and Tissue Research","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2071069499"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060074222","display_name":"Noriaki Takahashi","orcid":"https://orcid.org/0000-0001-8735-2794","observed_orcids":["https://orcid.org/0000-0001-8735-2794"]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriaki Takahashi","raw_affiliation_strings":["Department of Oral Anatomy School of Dentistry, Iwate Medical University, Chuo-dori 1\u20133\u201327, Morioka, 020\u20138505, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Anatomy School of Dentistry, Iwate Medical University, Chuo-dori 1\u20133\u201327, Morioka, 020\u20138505, Japan","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015963571","display_name":"Tokio Nawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tokio Nawa","raw_affiliation_strings":["Department of Oral Anatomy School of Dentistry, Iwate Medical University, Chuo-dori 1\u20133\u201327, Morioka, 020\u20138505, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Anatomy School of Dentistry, Iwate Medical University, Chuo-dori 1\u20133\u201327, Morioka, 020\u20138505, Japan","institution_ids":["https://openalex.org/I180680657"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042750121","display_name":"Kiyoto Ishizeki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180680657","display_name":"Iwate Medical University","ror":"https://ror.org/04cybtr86","country_code":"JP","type":"education","lineage":["https://openalex.org/I180680657"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kiyoto Ishizeki","raw_affiliation_strings":["Department of Oral Anatomy, School of Dentistry, Iwate Medical University, Chuo-dori 1-3-27, Morioka 020-8505, Japan. ishizeki@iwate-med.ac.jp","Department of Oral Anatomy School of Dentistry, Iwate Medical University, Chuo-dori 1\u20133\u201327, Morioka, 020\u20138505, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Anatomy, School of Dentistry, Iwate Medical University, Chuo-dori 1-3-27, Morioka 020-8505, Japan. ishizeki@iwate-med.ac.jp","institution_ids":["https://openalex.org/I180680657"]},{"raw_affiliation_string":"Department of Oral Anatomy School of Dentistry, Iwate Medical University, Chuo-dori 1\u20133\u201327, Morioka, 020\u20138505, Japan","institution_ids":["https://openalex.org/I180680657"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042750121"],"corresponding_institution_ids":["https://openalex.org/I180680657"],"apc_list":{"value":5290,"currency":"USD","value_usd":5290},"apc_paid":null,"fwci":0.804,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.69680133,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"309","issue":"2","first_page":"251","last_page":"260"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.5903000235557556,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.5903000235557556,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.1875,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.07050000131130219,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.8550000190734863},{"id":"https://openalex.org/keywords/chondrocytes","display_name":"chondrocytes","score":0.8320000171661377},{"id":"https://openalex.org/keywords/meckel-s-cartilage","display_name":"Meckel's cartilage","score":0.9929999709129333},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.5870000123977661},{"id":"https://openalex.org/keywords/dna-synthesis-inhibition","display_name":"DNA synthesis inhibition","score":0.7059999704360962},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8949999809265137},{"id":"https://openalex.org/keywords/lipid-droplets","display_name":"lipid droplets","score":0.9229999780654907},{"id":"https://openalex.org/keywords/ucp1","display_name":"UCP1","score":0.9110000133514404},{"id":"https://openalex.org/keywords/ppargamma","display_name":"PPAR\u03b3","score":0.9160000085830688},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.996999979019165},{"id":"https://openalex.org/keywords/glucose-transporter-4","display_name":"glucose transporter 4","score":0.8500000238418579},{"id":"https://openalex.org/keywords/white-adipocytes","display_name":"white adipocytes","score":0.9330000281333923},{"id":"https://openalex.org/keywords/phenotypic-change","display_name":"phenotypic change","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C25095133","wikidata":"https://www.wikidata.org/wiki/Q573950","display_name":"Lipid droplet","level":2,"score":0.7122986316680908},{"id":"https://openalex.org/C35866371","wikidata":"https://www.wikidata.org/wiki/Q6005502","display_name":"Immunocytochemistry","level":2,"score":0.5925521850585938},{"id":"https://openalex.org/C2780806160","wikidata":"https://www.wikidata.org/wiki/Q132442","display_name":"Oil Red O","level":4,"score":0.543644905090332},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.538555920124054},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5100146532058716},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.4965272545814514},{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.4838325083255768},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4674680233001709},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4612194001674652},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45395535230636597},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45244261622428894},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.4150850176811218},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.3276464641094208},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20711994171142578},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.10986727476119995},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000071256","descriptor_name":"Uncoupling Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009004","descriptor_name":"Monosaccharide Transport Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D020738","descriptor_name":"Leptin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051275","descriptor_name":"Glucose Transporter Type 4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00441-002-0541-z","doi":"https://doi.org/10.1007/s00441-002-0541-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00441-002-0541-z","pdf_url":null,"source":{"id":"https://openalex.org/S139399906","display_name":"Cell and Tissue Research","issn_l":"0302-766X","issn":["0302-766X","1432-0878"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell and Tissue Research","raw_type":"journal-article"},{"id":"pmid:12172784","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12172784","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell and tissue research","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1494277707","https://openalex.org/W1558589233","https://openalex.org/W1907219612","https://openalex.org/W1982292830","https://openalex.org/W1984309369","https://openalex.org/W1984902539","https://openalex.org/W1994335320","https://openalex.org/W1999978096","https://openalex.org/W2001783191","https://openalex.org/W2002519246","https://openalex.org/W2010500335","https://openalex.org/W2012295730","https://openalex.org/W2017906253","https://openalex.org/W2026812232","https://openalex.org/W2061132963","https://openalex.org/W2064953018","https://openalex.org/W2069430618","https://openalex.org/W2071692398","https://openalex.org/W2081981669","https://openalex.org/W2088747028","https://openalex.org/W2094115400","https://openalex.org/W2108409970","https://openalex.org/W2117876502","https://openalex.org/W2129138669","https://openalex.org/W2159270178","https://openalex.org/W2159999899","https://openalex.org/W2168880873","https://openalex.org/W2505230074"],"related_works":["https://openalex.org/W1976253821","https://openalex.org/W7164632248","https://openalex.org/W1992547681","https://openalex.org/W2027439781","https://openalex.org/W2765608334","https://openalex.org/W2363812380","https://openalex.org/W2169915942","https://openalex.org/W1988557299","https://openalex.org/W1973644617","https://openalex.org/W2055374048"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}