{"id":"https://openalex.org/W2070520171","doi":"https://doi.org/10.1111/j.1749-6632.1978.tb31507.x","title":"MODE AND MECHANISM OF ACTION OF NEUROTOXIC INDOLEAMINES: A REVIEW AND A PROGRESS REPORT","display_name":"MODE AND MECHANISM OF ACTION OF NEUROTOXIC INDOLEAMINES: A REVIEW AND A PROGRESS REPORT","publication_year":1978,"publication_date":"1978-06-01","ids":{"openalex":"https://openalex.org/W2070520171","doi":"https://doi.org/10.1111/j.1749-6632.1978.tb31507.x","mag":"2070520171","pmid":"https://pubmed.ncbi.nlm.nih.gov/360937"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1978.tb31507.x","doi":"https://doi.org/10.1111/j.1749-6632.1978.tb31507.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1978.tb31507.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113503883","display_name":"H. G. Baumgarten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. G. Baumgarten","raw_affiliation_strings":["Department of Functional Anatomy, University of Hamburg, 2000 Hamburg, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Functional Anatomy, University of Hamburg, 2000 Hamburg, Federal Republic of Germany","institution_ids":["https://openalex.org/I159176309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111581440","display_name":"H. P. Klemm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. P. Klemm","raw_affiliation_strings":["Department of Functional Anatomy, University of Hamburg, 2000 Hamburg, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Functional Anatomy, University of Hamburg, 2000 Hamburg, Federal Republic of Germany","institution_ids":["https://openalex.org/I159176309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112357229","display_name":"L. Lachenmayer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"L. Lachenmayer","raw_affiliation_strings":["Department of Functional Anatomy, University of Hamburg, 2000 Hamburg, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Functional Anatomy, University of Hamburg, 2000 Hamburg, Federal Republic of Germany","institution_ids":["https://openalex.org/I159176309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047762447","display_name":"Anders Bj\u00f6rklund","orcid":"https://orcid.org/0000-0002-5676-6203","observed_orcids":["https://orcid.org/0000-0002-5676-6203"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"A. Bj\u00f6rklund","raw_affiliation_strings":["Department of Histology, University of Lund, S-223 62 Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology, University of Lund, S-223 62 Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061188066","display_name":"Walter M. Lovenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Lovenberg","raw_affiliation_strings":["Section on Biochemical Pharmacology, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Biochemical Pharmacology, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20014","institution_ids":["https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":null,"display_name":"H. G. Schlossberger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210150093","display_name":"Max Planck Institute of Biochemistry","ror":"https://ror.org/04py35477","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210150093"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. G. Schlossberger","raw_affiliation_strings":["Department of Organic Chemistry and Spectroscopy, Max Planck Institute for Biochemistry, 8033 Martinsried, Munich, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry and Spectroscopy, Max Planck Institute for Biochemistry, 8033 Martinsried, Munich, Federal Republic of Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210150093"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":0.5013,"has_fulltext":false,"cited_by_count":78,"citation_normalized_percentile":{"value":0.42553191,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"305","issue":"1","first_page":"3","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.46000000834465027,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.46000000834465027,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.2280000001192093,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.11400000005960464,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mechanism-of-action","display_name":"mechanism of action","score":0.718999981880188},{"id":"https://openalex.org/keywords/neurotoxicity-mechanisms","display_name":"neurotoxicity mechanisms","score":0.6880000233650208},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.35100001096725464}],"concepts":[{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.3979288339614868},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3772926330566406},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.07662197947502136}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001679","descriptor_name":"Biogenic Amines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002946","descriptor_name":"Cisterna Magna","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004102","descriptor_name":"Dihydroxytryptamines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004102","descriptor_name":"Dihydroxytryptamines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007267","descriptor_name":"Injections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007276","descriptor_name":"Injections, Intraventricular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1749-6632.1978.tb31507.x","doi":"https://doi.org/10.1111/j.1749-6632.1978.tb31507.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1978.tb31507.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:360937","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/360937","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4043000042438507}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W230278952","https://openalex.org/W330827285","https://openalex.org/W1968259305","https://openalex.org/W1972610895","https://openalex.org/W1979379383","https://openalex.org/W1999774778","https://openalex.org/W2005302369","https://openalex.org/W2006356056","https://openalex.org/W2015768769","https://openalex.org/W2042038355","https://openalex.org/W2049378567","https://openalex.org/W2068852450","https://openalex.org/W2072750335","https://openalex.org/W2075332582","https://openalex.org/W2076102718","https://openalex.org/W2081253940","https://openalex.org/W2092492853","https://openalex.org/W2093975095","https://openalex.org/W2101459312","https://openalex.org/W2135112754","https://openalex.org/W2137348484","https://openalex.org/W2160824435","https://openalex.org/W2246813284","https://openalex.org/W2398317719","https://openalex.org/W2399629383","https://openalex.org/W2410170081","https://openalex.org/W2410468845","https://openalex.org/W2415185405","https://openalex.org/W2416582794","https://openalex.org/W2436358829","https://openalex.org/W2472351891","https://openalex.org/W2887092660","https://openalex.org/W2896263842","https://openalex.org/W4230090642"],"related_works":["https://openalex.org/W2092345798","https://openalex.org/W4406986010","https://openalex.org/W1986635062","https://openalex.org/W2095091349","https://openalex.org/W2417061415","https://openalex.org/W3169782452","https://openalex.org/W4235704438","https://openalex.org/W2409626576","https://openalex.org/W2411857796","https://openalex.org/W2093093151"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}