{"id":"https://openalex.org/W2070516629","doi":"https://doi.org/10.1128/jvi.06434-11","title":"Deep Sequencing Identifies Viral and Wasp Genes with Potential Roles in Replication of Microplitis demolitor Bracovirus","display_name":"Deep Sequencing Identifies Viral and Wasp Genes with Potential Roles in Replication of Microplitis demolitor Bracovirus","publication_year":2012,"publication_date":"2012-01-11","ids":{"openalex":"https://openalex.org/W2070516629","doi":"https://doi.org/10.1128/jvi.06434-11","mag":"2070516629","pmid":"https://pubmed.ncbi.nlm.nih.gov/22238295","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3302316"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.06434-11","doi":"https://doi.org/10.1128/jvi.06434-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.06434-11","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3302316","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020181550","display_name":"Gaelen R. Burke","orcid":"https://orcid.org/0000-0003-3472-0420","observed_orcids":["https://orcid.org/0000-0003-3472-0420"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gaelen R. Burke","raw_affiliation_strings":["Department of Entomology, University of Georgia, Athens, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Entomology, University of Georgia, Athens, Georgia, USA","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050516508","display_name":"Michael R. Strand","orcid":"https://orcid.org/0000-0003-1844-7460","observed_orcids":["https://orcid.org/0000-0003-1844-7460"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael R. Strand","raw_affiliation_strings":["Department of Entomology, University of Georgia, Athens, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Entomology, University of Georgia, Athens, Georgia, USA","institution_ids":["https://openalex.org/I165733156"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I165733156"],"apc_list":null,"apc_paid":null,"fwci":10.7771,"has_fulltext":false,"cited_by_count":84,"citation_normalized_percentile":{"value":0.9883937,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"86","issue":"6","first_page":"3293","last_page":"3306"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12132","display_name":"Hymenoptera taxonomy and phylogeny","score":0.23250000178813934,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12132","display_name":"Hymenoptera taxonomy and phylogeny","score":0.23250000178813934,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.22050000727176666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13220","display_name":"Plant and Fungal Interactions Research","score":0.05180000141263008,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bracovirus","display_name":"bracovirus","score":0.9700000286102295},{"id":"https://openalex.org/keywords/viral-replication","display_name":"viral replication","score":0.6779999732971191},{"id":"https://openalex.org/keywords/ovary-transcriptome","display_name":"ovary transcriptome","score":0.781000018119812},{"id":"https://openalex.org/keywords/wasp-gene","display_name":"WASP gene","score":0.5569999814033508},{"id":"https://openalex.org/keywords/dna-amplification","display_name":"DNA amplification","score":0.6050000190734863},{"id":"https://openalex.org/keywords/cotesia-congregata","display_name":"Cotesia congregata","score":0.7400000095367432},{"id":"https://openalex.org/keywords/chelonus-inanitus","display_name":"Chelonus inanitus","score":0.9860000014305115}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.954638659954071},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6418585181236267},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.635316789150238},{"id":"https://openalex.org/C7452308","wikidata":"https://www.wikidata.org/wiki/Q3112822","display_name":"Rolling circle replication","level":4,"score":0.5793869495391846},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.5094485878944397},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.42601656913757324},{"id":"https://openalex.org/C58337764","wikidata":"https://www.wikidata.org/wiki/Q976651","display_name":"Origin of replication","level":4,"score":0.42491084337234497},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.3320836126804352},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.11326280236244202}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D018071","descriptor_name":"Polydnaviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018071","descriptor_name":"Polydnaviridae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D018071","descriptor_name":"Polydnaviridae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.06434-11","doi":"https://doi.org/10.1128/jvi.06434-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.06434-11","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3302316","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3302316","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:22238295","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22238295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3302316","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3302316","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2804447514","display_name":"Functional analysis of a symbiotic polydnavirus","funder_award_id":"F32AI096552","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1964866179","https://openalex.org/W1985924390","https://openalex.org/W1987328221","https://openalex.org/W1996423252","https://openalex.org/W1999113367","https://openalex.org/W2005437607","https://openalex.org/W2011064394","https://openalex.org/W2015551032","https://openalex.org/W2018212701","https://openalex.org/W2028573570","https://openalex.org/W2030379752","https://openalex.org/W2037562736","https://openalex.org/W2041892385","https://openalex.org/W2046506207","https://openalex.org/W2053555218","https://openalex.org/W2055043387","https://openalex.org/W2064909392","https://openalex.org/W2068581113","https://openalex.org/W2074682770","https://openalex.org/W2076896228","https://openalex.org/W2093837573","https://openalex.org/W2094758748","https://openalex.org/W2095088685","https://openalex.org/W2095289686","https://openalex.org/W2097233732","https://openalex.org/W2097837547","https://openalex.org/W2099762521","https://openalex.org/W2103441770","https://openalex.org/W2108234281","https://openalex.org/W2109808405","https://openalex.org/W2113600043","https://openalex.org/W2115852216","https://openalex.org/W2118777254","https://openalex.org/W2119539742","https://openalex.org/W2119716854","https://openalex.org/W2123930895","https://openalex.org/W2125865118","https://openalex.org/W2130164103","https://openalex.org/W2132926880","https://openalex.org/W2141885858","https://openalex.org/W2146003375","https://openalex.org/W2150517126","https://openalex.org/W2152740529","https://openalex.org/W2153379351","https://openalex.org/W2154431984","https://openalex.org/W2154472780","https://openalex.org/W2157399331","https://openalex.org/W2157840525","https://openalex.org/W2158093748","https://openalex.org/W2160969485","https://openalex.org/W2163221081","https://openalex.org/W2167194725","https://openalex.org/W2168696662","https://openalex.org/W2171075467","https://openalex.org/W2171701745","https://openalex.org/W2234965527","https://openalex.org/W2262997221","https://openalex.org/W2313130252","https://openalex.org/W2476186280","https://openalex.org/W4210623056"],"related_works":["https://openalex.org/W7169617365","https://openalex.org/W4387930886","https://openalex.org/W1848902369","https://openalex.org/W7096891371","https://openalex.org/W2039787869","https://openalex.org/W7172508811","https://openalex.org/W3132794694","https://openalex.org/W2097837547","https://openalex.org/W1981129106","https://openalex.org/W2310225347"],"abstract_inverted_index":{"Viruses":[0],"in":[1,15,111,117,147,197],"the":[2,16,148,214,243],"genus":[3],"Bracovirus":[4],"(BV)":[5],"(Polydnaviridae)":[6],"are":[7,220],"symbionts":[8],"of":[9,18,22,72,99,120,129,138,145,156,162,178,216,232,246],"parasitoid":[10],"wasps":[11,64],"that":[12,51,107,131,141,181,219,230],"specifically":[13],"replicate":[14],"ovaries":[17],"females.":[19],"Recent":[20],"analysis":[21],"expressed":[23,168,184],"sequence":[24,130],"tags":[25],"from":[26,54],"two":[27],"wasp":[28,73,179],"species,":[29],"Cotesia":[30],"congregata":[31],"and":[32,69,94,115,122],"Chelonus":[33],"inanitus,":[34],"identified":[35,175],"transcripts":[36,159,193],"related":[37],"to":[38],"24":[39],"different":[40],"nudivirus":[41,56],"genes.":[42],"These":[43],"results":[44,105,173,211,227],"together":[45,208],"with":[46,194,209],"other":[47,66],"data":[48,206],"strongly":[49],"indicate":[50],"BVs":[52],"evolved":[53],"a":[55,142,164,176],"ancestor.":[57],"However,":[58],"it":[59],"remains":[60],"unclear":[61],"whether":[62],"BV-carrying":[63],"contain":[65],"nudivirus-like":[67,158],"genes":[68,74,146,180,218],"what":[70],"types":[71],"may":[75,240],"also":[76,174,228],"be":[77],"required":[78],"for":[79,235],"BV":[80,224,238],"replication.":[81,171,187,225],"Microplitis":[82,85],"demolitor":[83,86,101,150],"carries":[84],"bracovirus":[87],"(MdBV).":[88],"Here":[89],"we":[90],"characterized":[91],"MdBV":[92,108,170,186],"replication":[93,109,244],"performed":[95],"massively":[96],"parallel":[97],"sequencing":[98],"M.":[100,149],"ovary":[102,124],"transcripts.":[103,135],"Our":[104,172,226],"indicated":[106,140],"begins":[110],"stage":[112],"2":[113],"pupae":[114],"continues":[116],"adults.":[118],"Analysis":[119],"prereplication-":[121],"active-replication-stage":[123],"RNAs":[125],"yielded":[126],"22":[127],"Gb":[128],"assembled":[132],"into":[133,237],"66,425":[134],"This":[136],"breadth":[137],"sampling":[139],"large":[143],"percentage":[144],"genome":[151],"were":[152,160,166,182,191],"sequenced.":[153],"A":[154],"total":[155],"41":[157],"identified,":[161],"which":[163],"majority":[165,215],"highly":[167,183],"during":[169,185,223],"suite":[177],"Among":[188],"these":[189],"products":[190],"several":[192],"conserved":[195],"roles":[196],"regulating":[198],"locus-specific":[199],"DNA":[200],"amplification":[201,231],"by":[202],"eukaryotes.":[203],"Overall,":[204],"our":[205],"set":[207],"prior":[210],"likely":[212],"identify":[213],"nudivirus-related":[217],"transcriptionally":[221],"functional":[222],"suggest":[229],"proviral":[233],"DNAs":[234],"packaging":[236],"virions":[239],"depend":[241],"upon":[242],"machinery":[245],"wasps.":[247]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}