{"id":"https://openalex.org/W2070145121","doi":"https://doi.org/10.5115/acb.2012.45.4.229","title":"Preliminary morphological and biochemical changes in rat liver following postnatal exposure to sodium arsenite","display_name":"Preliminary morphological and biochemical changes in rat liver following postnatal exposure to sodium arsenite","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2070145121","doi":"https://doi.org/10.5115/acb.2012.45.4.229","mag":"2070145121","pmid":"https://pubmed.ncbi.nlm.nih.gov/23301191","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3531587"},"language":"en","primary_location":{"id":"doi:10.5115/acb.2012.45.4.229","doi":"https://doi.org/10.5115/acb.2012.45.4.229","is_oa":false,"landing_page_url":"https://doi.org/10.5115/acb.2012.45.4.229","pdf_url":null,"source":{"id":"https://openalex.org/S103125610","display_name":"Anatomy & Cell Biology","issn_l":"2093-3665","issn":["2093-3665","2093-3673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","kci-registered","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anatomy &amp; Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3531587/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Arnab Bhattacharya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Arnab Bhattacharya","raw_affiliation_strings":["Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034024418","display_name":"Pushpa Dhar","orcid":"https://orcid.org/0000-0003-2696-7466","observed_orcids":["https://orcid.org/0000-0003-2696-7466"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Pushpa Dhar","raw_affiliation_strings":["Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111373566","display_name":"Raj D. Mehra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Raj D. Mehra","raw_affiliation_strings":["Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5034024418"],"corresponding_institution_ids":["https://openalex.org/I63739035"],"apc_list":null,"apc_paid":null,"fwci":0.4312,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.57842542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"45","issue":"4","first_page":"229","last_page":"229"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10710","display_name":"Arsenic contamination and mitigation","score":0.7484999895095825,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10710","display_name":"Arsenic contamination and mitigation","score":0.7484999895095825,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.15539999306201935,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.026900000870227814,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sodium-arsenite","display_name":"sodium arsenite","score":0.9990000128746033},{"id":"https://openalex.org/keywords/arsenic-toxicity","display_name":"arsenic toxicity","score":0.8600000143051147},{"id":"https://openalex.org/keywords/postnatal-liver-development","display_name":"postnatal liver development","score":0.7300000190734863},{"id":"https://openalex.org/keywords/hepatocyte-maturation","display_name":"hepatocyte maturation","score":0.7730000019073486},{"id":"https://openalex.org/keywords/lipid-droplets","display_name":"lipid droplets","score":0.8640000224113464},{"id":"https://openalex.org/keywords/reduced-glutathione","display_name":"reduced glutathione","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hepatic-lobule","display_name":"hepatic lobule","score":0.6489999890327454},{"id":"https://openalex.org/keywords/liver-morphogenesis","display_name":"liver morphogenesis","score":0.3779999911785126},{"id":"https://openalex.org/keywords/rat-liver","display_name":"rat liver","score":0.48399999737739563}],"concepts":[{"id":"https://openalex.org/C2779495234","wikidata":"https://www.wikidata.org/wiki/Q419586","display_name":"Sodium arsenite","level":3,"score":0.8257431983947754},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.8186219930648804},{"id":"https://openalex.org/C125473707","wikidata":"https://www.wikidata.org/wiki/Q9914","display_name":"H&E stain","level":3,"score":0.5729022026062012},{"id":"https://openalex.org/C2779429693","wikidata":"https://www.wikidata.org/wiki/Q274959","display_name":"Distilled water","level":2,"score":0.5440972447395325},{"id":"https://openalex.org/C2779751288","wikidata":"https://www.wikidata.org/wiki/Q422637","display_name":"Eosin","level":3,"score":0.5056824684143066},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4984104633331299},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.496114581823349},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.4479863941669464},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4236978590488434},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4139062464237213},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.34322071075439453},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2223101258277893},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1620948612689972},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1276831030845642},{"id":"https://openalex.org/C502230775","wikidata":"https://www.wikidata.org/wiki/Q871","display_name":"Arsenic","level":2,"score":0.10713139176368713},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5115/acb.2012.45.4.229","doi":"https://doi.org/10.5115/acb.2012.45.4.229","is_oa":false,"landing_page_url":"https://doi.org/10.5115/acb.2012.45.4.229","pdf_url":null,"source":{"id":"https://openalex.org/S103125610","display_name":"Anatomy & Cell Biology","issn_l":"2093-3665","issn":["2093-3665","2093-3673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","kci-registered","poland-70","russia-white-list-2","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anatomy &amp; Cell Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3531587","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3531587/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3531587/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anat Cell Biol","raw_type":"Text"},{"id":"pmid:23301191","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23301191","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anatomy & cell biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3531587","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3531587/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3531587/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anat Cell Biol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320324337","display_name":"All-India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2070145121.pdf","grobid_xml":"https://content.openalex.org/works/W2070145121.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W46832102","https://openalex.org/W168822901","https://openalex.org/W169865300","https://openalex.org/W179721640","https://openalex.org/W209888804","https://openalex.org/W210022707","https://openalex.org/W210963696","https://openalex.org/W229437497","https://openalex.org/W239147895","https://openalex.org/W1408881898","https://openalex.org/W1490841497","https://openalex.org/W1497272095","https://openalex.org/W1503393361","https://openalex.org/W1516221483","https://openalex.org/W1534618416","https://openalex.org/W1543546710","https://openalex.org/W1558031393","https://openalex.org/W1560607431","https://openalex.org/W1594707227","https://openalex.org/W1815255263","https://openalex.org/W1965718227","https://openalex.org/W1972478649","https://openalex.org/W1975639741","https://openalex.org/W1975793650","https://openalex.org/W1978892642","https://openalex.org/W1979685062","https://openalex.org/W1990995698","https://openalex.org/W1994569896","https://openalex.org/W2001851023","https://openalex.org/W2006370393","https://openalex.org/W2026650560","https://openalex.org/W2033382570","https://openalex.org/W2035564064","https://openalex.org/W2040021378","https://openalex.org/W2049733463","https://openalex.org/W2050223321","https://openalex.org/W2050911272","https://openalex.org/W2053297360","https://openalex.org/W2064912565","https://openalex.org/W2066393569","https://openalex.org/W2069132215","https://openalex.org/W2074035163","https://openalex.org/W2075847037","https://openalex.org/W2078826273","https://openalex.org/W2080073380","https://openalex.org/W2083281046","https://openalex.org/W2104466802","https://openalex.org/W2110376919","https://openalex.org/W2114823840","https://openalex.org/W2115926218","https://openalex.org/W2126696387","https://openalex.org/W2134204461","https://openalex.org/W2140701797","https://openalex.org/W2150748986","https://openalex.org/W2152527807","https://openalex.org/W2155689289","https://openalex.org/W2156425202","https://openalex.org/W2160073127","https://openalex.org/W2164289715","https://openalex.org/W2172122750","https://openalex.org/W2253293478","https://openalex.org/W2402013419","https://openalex.org/W2406270761","https://openalex.org/W2415285857","https://openalex.org/W2487105216","https://openalex.org/W2612300022","https://openalex.org/W2791114118","https://openalex.org/W2912200855","https://openalex.org/W2949966509","https://openalex.org/W4291278292"],"related_works":["https://openalex.org/W2560494965","https://openalex.org/W4409433847","https://openalex.org/W3013863526","https://openalex.org/W1994569896","https://openalex.org/W2094929226","https://openalex.org/W2947036197","https://openalex.org/W1983489012","https://openalex.org/W3162364658","https://openalex.org/W3036419388","https://openalex.org/W2922305443"],"abstract_inverted_index":{"The":[0,58,74,117,184],"effects":[1],"of":[2,11,26,92,105,123,155,173,177,197,207],"sodium":[3,27],"arsenite":[4,28],"exposure":[5,215],"on":[6,36],"the":[7,46,111,114,124,129,147,174,178,189,193,198,201,205,217],"hepatic":[8,100],"maturation":[9],"period":[10],"cellular":[12],"and":[13,69,71,88,103,107,113,121,170,192,209],"functional":[14],"reorganization":[15],"in":[16,110,128,136,150,163,167,176,181,188,200],"developing":[17],"rat":[18],"livers":[19],"were":[20,48],"evaluated.":[21],"Animals":[22],"received":[23],"intraperitoneal":[24],"injections":[25],"(1.5":[29],"mg/kg":[30],"body":[31],"weight)":[32],"or":[33,54],"distilled":[34],"water":[35],"days":[37],"9":[38],"to":[39],"28":[40],"after":[41],"birth.":[42],"On":[43],"day":[44],"29,":[45],"animals":[47],"sacrificed":[49],"either":[50],"by":[51,55,83,213],"cervical":[52],"dislocation":[53],"perfusion":[56,59],"fixation.":[57],"fixed":[60],"liver":[61,76,190],"tissue":[62,77,191],"was":[63,78,126],"processed":[64,79],"for":[65,80,89],"paraffin":[66],"embedding,":[67],"sectioning":[68],"hematoxylin":[70],"eosin":[72],"staining.":[73],"fresh":[75],"cryo-sectioning":[81],"followed":[82],"Sudan":[84,137],"Black":[85,138],"B":[86,139],"staining":[87,144,156],"biochemical":[90,210],"estimation":[91,154],"reduced":[93,185],"glutathione.":[94],"Microscopic":[95],"observation":[96],"revealed":[97,142],"comparable":[98],"preserved":[99],"lobular":[101],"patterns":[102],"distributions":[104],"uninucleate":[106],"binucleate":[108],"hepatocytes":[109,125,199],"control":[112],"experimental":[115,130,202],"groups.":[116,152,183],"mean":[118,160],"nuclear":[119,195],"area":[120,149],"diameter":[122],"increased":[127],"group.":[131],"Lipid":[132],"droplet":[133],"distribution":[134],"pattern":[135],"stained":[140],"sections":[141],"higher":[143],"intensity":[145,157],"towards":[146],"centrilobular":[148],"both":[151,182],"Semiquantitative":[153],"showed":[158],"lower":[159],"gray":[161],"values":[162],"zone":[164],"3":[165],"than":[166],"zones":[168],"2":[169],"1":[171],"(suggestive":[172],"setting":[175],"adult":[179],"pattern)":[180],"glutathione":[186],"levels":[187],"altered":[194],"size":[196],"group":[203],"suggested":[204],"impairment":[206],"morphological":[208],"processes":[211],"induced":[212],"arsenic":[214],"during":[216],"postnatal":[218],"period.":[219]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}
