{"id":"https://openalex.org/W2070127013","doi":"https://doi.org/10.1111/mec.12648","title":"Systematic analysis of a wasp parasitism arsenal","display_name":"Systematic analysis of a wasp parasitism arsenal","publication_year":2014,"publication_date":"2014-01-03","ids":{"openalex":"https://openalex.org/W2070127013","doi":"https://doi.org/10.1111/mec.12648","mag":"2070127013","pmid":"https://pubmed.ncbi.nlm.nih.gov/24383716","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4120856"},"language":"en","primary_location":{"id":"doi:10.1111/mec.12648","doi":"https://doi.org/10.1111/mec.12648","is_oa":false,"landing_page_url":"https://doi.org/10.1111/mec.12648","pdf_url":null,"source":{"id":"https://openalex.org/S22454499","display_name":"Molecular Ecology","issn_l":"0962-1083","issn":["0962-1083","1365-294X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Ecology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4120856","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020181550","display_name":"Gaelen R. Burke","orcid":"https://orcid.org/0000-0003-3472-0420","observed_orcids":["https://orcid.org/0000-0003-3472-0420"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gaelen R. Burke","raw_affiliation_strings":["Department of Entomology University of Georgia 120 Cedar St, 420 Biological Sciences Building Athens GA 30602 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Entomology University of Georgia 120 Cedar St, 420 Biological Sciences Building Athens GA 30602 USA","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050516508","display_name":"Michael R. Strand","orcid":"https://orcid.org/0000-0003-1844-7460","observed_orcids":["https://orcid.org/0000-0003-1844-7460"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael R. Strand","raw_affiliation_strings":["Department of Entomology University of Georgia 120 Cedar St, 420 Biological Sciences Building Athens GA 30602 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Entomology University of Georgia 120 Cedar St, 420 Biological Sciences Building Athens GA 30602 USA","institution_ids":["https://openalex.org/I165733156"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I165733156"],"apc_list":{"value":5150,"currency":"USD","value_usd":5150},"apc_paid":null,"fwci":16.4353,"has_fulltext":false,"cited_by_count":132,"citation_normalized_percentile":{"value":0.99591164,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"23","issue":"4","first_page":"890","last_page":"901"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12132","display_name":"Hymenoptera taxonomy and phylogeny","score":0.7749000191688538,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12132","display_name":"Hymenoptera taxonomy and phylogeny","score":0.7749000191688538,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.1306000053882599,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10702","display_name":"Insect and Arachnid Ecology and Behavior","score":0.04610000178217888,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parasitoid-wasps","display_name":"parasitoid wasps","score":0.9779999852180481},{"id":"https://openalex.org/keywords/microplitis-demolitor","display_name":"Microplitis demolitor","score":0.9829999804496765},{"id":"https://openalex.org/keywords/polydnavirus","display_name":"polydnavirus","score":0.9179999828338623},{"id":"https://openalex.org/keywords/teratocytes","display_name":"teratocytes","score":0.9599999785423279},{"id":"https://openalex.org/keywords/larval-secretions","display_name":"larval secretions","score":0.7170000076293945},{"id":"https://openalex.org/keywords/hymenoptaecin","display_name":"hymenoptaecin","score":0.9470000267028809},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.9679999947547913},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9150000214576721},{"id":"https://openalex.org/keywords/gene-duplication","display_name":"gene duplication","score":0.6970000267028809},{"id":"https://openalex.org/keywords/effector-molecules","display_name":"effector molecules","score":0.7860000133514404},{"id":"https://openalex.org/keywords/host-parasitoid-interactions","display_name":"host-parasitoid interactions","score":0.7749999761581421}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9598118662834167},{"id":"https://openalex.org/C2779448229","wikidata":"https://www.wikidata.org/wiki/Q3386847","display_name":"Venom","level":2,"score":0.8618664741516113},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.6239756345748901},{"id":"https://openalex.org/C2778234367","wikidata":"https://www.wikidata.org/wiki/Q186517","display_name":"Parasitism","level":3,"score":0.6047274470329285},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5895912647247314},{"id":"https://openalex.org/C540938839","wikidata":"https://www.wikidata.org/wiki/Q1201508","display_name":"Antimicrobial peptides","level":3,"score":0.5677769780158997},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.5483412146568298},{"id":"https://openalex.org/C2780541402","wikidata":"https://www.wikidata.org/wiki/Q18398438","display_name":"Parasitoid wasp","level":4,"score":0.5438916683197021},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.47734692692756653},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4099442660808563},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.4022653102874756},{"id":"https://openalex.org/C2778260489","wikidata":"https://www.wikidata.org/wiki/Q595663","display_name":"Parasitoid","level":3,"score":0.38270747661590576},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.25287437438964844},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.20963004231452942},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.12259098887443542}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013559","descriptor_name":"Symbiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014862","descriptor_name":"Wasp Venoms","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014862","descriptor_name":"Wasp Venoms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014863","descriptor_name":"Wasps","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D018071","descriptor_name":"Polydnaviridae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/mec.12648","doi":"https://doi.org/10.1111/mec.12648","is_oa":false,"landing_page_url":"https://doi.org/10.1111/mec.12648","pdf_url":null,"source":{"id":"https://openalex.org/S22454499","display_name":"Molecular Ecology","issn_l":"0962-1083","issn":["0962-1083","1365-294X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Ecology","raw_type":"journal-article"},{"id":"pmid:24383716","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24383716","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular ecology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4120856","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4120856","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mol Ecol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4120856","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4120856","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mol Ecol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2804447514","display_name":"Functional analysis of a symbiotic polydnavirus","funder_award_id":"F32AI096552","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5137877478","display_name":null,"funder_award_id":"2009-35302-05250","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G8725822586","display_name":null,"funder_award_id":"IOS-1261328","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8824458188","display_name":"Purchase of a Thermo Fisher Scientific LTQ Orbitrap XL Mass Spectrometer","funder_award_id":"S10RR028859","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320310010","display_name":"University of Georgia","ror":"https://ror.org/00te3t702"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W153843189","https://openalex.org/W1488354887","https://openalex.org/W1500989553","https://openalex.org/W1519266993","https://openalex.org/W1970021975","https://openalex.org/W1970867633","https://openalex.org/W1971817690","https://openalex.org/W1973528718","https://openalex.org/W1975989231","https://openalex.org/W1980116322","https://openalex.org/W1980278573","https://openalex.org/W1985478747","https://openalex.org/W1985924390","https://openalex.org/W1987683310","https://openalex.org/W1992453531","https://openalex.org/W1993459848","https://openalex.org/W1999113367","https://openalex.org/W2001926990","https://openalex.org/W2006029090","https://openalex.org/W2011064394","https://openalex.org/W2011931604","https://openalex.org/W2016418963","https://openalex.org/W2017617217","https://openalex.org/W2019292563","https://openalex.org/W2024423461","https://openalex.org/W2025814151","https://openalex.org/W2028190875","https://openalex.org/W2028302194","https://openalex.org/W2028617363","https://openalex.org/W2031121492","https://openalex.org/W2033851989","https://openalex.org/W2046682883","https://openalex.org/W2048912867","https://openalex.org/W2052213433","https://openalex.org/W2054522616","https://openalex.org/W2060780659","https://openalex.org/W2062884129","https://openalex.org/W2062936863","https://openalex.org/W2064189029","https://openalex.org/W2064320129","https://openalex.org/W2070516629","https://openalex.org/W2074682770","https://openalex.org/W2080967293","https://openalex.org/W2092833830","https://openalex.org/W2093504978","https://openalex.org/W2093886113","https://openalex.org/W2095088685","https://openalex.org/W2095289686","https://openalex.org/W2097837547","https://openalex.org/W2103441770","https://openalex.org/W2105471305","https://openalex.org/W2111643931","https://openalex.org/W2112065041","https://openalex.org/W2122989295","https://openalex.org/W2123930895","https://openalex.org/W2126419817","https://openalex.org/W2130412849","https://openalex.org/W2135621733","https://openalex.org/W2135728869","https://openalex.org/W2141885858","https://openalex.org/W2145837099","https://openalex.org/W2146857914","https://openalex.org/W2149860086","https://openalex.org/W2149880091","https://openalex.org/W2154431984","https://openalex.org/W2154943592","https://openalex.org/W2165949801","https://openalex.org/W2168696662","https://openalex.org/W2169089697","https://openalex.org/W2493454677","https://openalex.org/W2611511275","https://openalex.org/W2911774838","https://openalex.org/W4240799539","https://openalex.org/W4320301318"],"related_works":["https://openalex.org/W236037734","https://openalex.org/W2493454677","https://openalex.org/W107654309","https://openalex.org/W2906882159","https://openalex.org/W2038086361","https://openalex.org/W2026647769","https://openalex.org/W2025814151","https://openalex.org/W2111618510","https://openalex.org/W2162440212","https://openalex.org/W2312622755"],"abstract_inverted_index":{"Parasitoid":[0],"wasps":[1,39],"are":[2,140],"among":[3,201],"the":[4,60,79,153,182,197,235,240],"most":[5],"diverse":[6],"insects":[7],"on":[8],"earth":[9],"with":[10,127,215],"many":[11],"species":[12],"causing":[13],"major":[14],"mortality":[15],"in":[16,152,226],"host":[17,45],"populations.":[18],"Parasitoids":[19],"introduce":[20],"a":[21,109,242],"variety":[22],"of":[23,50,108,112,155,168,181,199,209,224,239],"factors":[24],"into":[25,59,246],"hosts":[26],"to":[27,42,64,77,115,144],"promote":[28],"parasitism,":[29],"including":[30],"symbiotic":[31],"viruses,":[32],"venom,":[33],"teratocytes":[34,85,104,177],"and":[35,47,73,86,103,117,120,157,205],"wasp":[36,244],"larvae.":[37,118],"Polydnavirus-carrying":[38],"use":[40],"viruses":[41,62],"globally":[43],"suppress":[44],"immunity":[46],"prevent":[48],"rejection":[49],"developing":[51],"parasites.":[52],"Although":[53],"prior":[54],"results":[55,233],"provide":[56,234],"detailed":[57],"insights":[58],"genes":[61,202],"deliver":[63],"hosts,":[65],"little":[66],"is":[67],"known":[68],"about":[69],"other":[70,218],"products.":[71],"RNAseq":[72],"proteomics":[74],"were":[75],"used":[76],"characterize":[78],"proteins":[80,161,216,241],"secreted":[81],"by":[82],"venom":[83,101,204,227],"glands,":[84],"larvae":[87],"from":[88,217],"Microplitis":[89],"demolitor,":[90],"which":[91,133,186],"carries":[92],"M.":[93,136],"demolitor":[94,137],"bracovirus":[95],"(MdBV).":[96],"These":[97],"data":[98],"revealed":[99],"that":[100,135,165,176],"glands":[102,228],"secrete":[105],"large":[106],"amounts":[107],"small":[110],"number":[111],"products":[113,122],"relative":[114],"ovaries":[116],"Venom":[119],"teratocyte":[121,206],"exhibited":[123],"almost":[124],"no":[125],"overlap":[126],"one":[128],"another":[129],"or":[130,229],"MdBV":[131,156],"genes,":[132],"suggested":[134],"effector":[138],"molecules":[139],"functionally":[141],"partitioned":[142],"according":[143],"their":[145],"source.":[146],"This":[147],"finding":[148,195],"was":[149,196],"well":[150],"illustrated":[151],"case":[154],"teratocytes.":[158,230],"Many":[159],"viral":[160],"have":[162],"immunosuppressive":[163],"functions":[164],"include":[166],"disruption":[167],"antimicrobial":[169,183],"peptide":[170,184],"production,":[171],"yet":[172],"this":[173],"study":[174],"showed":[175],"express":[178],"high":[179],"levels":[180],"hymenoptaecin,":[185],"likely":[187],"compensates":[188],"for":[189],"MdBV-mediated":[190],"immunosuppression.":[191],"A":[192],"second":[193],"key":[194],"prevalence":[198],"duplications":[200],"encoding":[203],"molecules.":[207],"Several":[208],"these":[210,232],"gene":[211],"families":[212],"share":[213],"similarities":[214],"species,":[219],"while":[220],"also":[221],"showing":[222],"specificity":[223],"expression":[225],"Overall,":[231],"first":[236],"comprehensive":[237],"analysis":[238],"polydnavirus-carrying":[243],"introduces":[245],"its":[247],"host.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":20},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}