{"id":"https://openalex.org/W2070118005","doi":"https://doi.org/10.1016/j.jim.2003.07.012","title":"TNF-\u03b1 detection using a flow cytometric assay to determine cellular responses to anthrax vaccine","display_name":"TNF-\u03b1 detection using a flow cytometric assay to determine cellular responses to anthrax vaccine","publication_year":2003,"publication_date":"2003-11-01","ids":{"openalex":"https://openalex.org/W2070118005","doi":"https://doi.org/10.1016/j.jim.2003.07.012","mag":"2070118005","pmid":"https://pubmed.ncbi.nlm.nih.gov/14604550"},"language":"en","primary_location":{"id":"doi:10.1016/j.jim.2003.07.012","doi":"https://doi.org/10.1016/j.jim.2003.07.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jim.2003.07.012","pdf_url":null,"source":{"id":"https://openalex.org/S201669150","display_name":"Journal of Immunological Methods","issn_l":"0022-1759","issn":["0022-1759","1872-7905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Immunological Methods","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023532953","display_name":"Annie H. Shinn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119942576","display_name":"University of the Pacific","ror":"https://ror.org/05ma4gw77","country_code":"US","type":"education","lineage":["https://openalex.org/I119942576"]},{"id":"https://openalex.org/I4210089612","display_name":"United States Air Force","ror":"https://ror.org/006gmme17","country_code":"US","type":"government","lineage":["https://openalex.org/I1330347796","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Annie H. Shinn","raw_affiliation_strings":["Thomas J Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA. hshinn@uop.edu","Clinical Investigation Facility, Travis AFB, CA, USA","Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thomas J Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA. hshinn@uop.edu","institution_ids":["https://openalex.org/I119942576"]},{"raw_affiliation_string":"Clinical Investigation Facility, Travis AFB, CA, USA","institution_ids":["https://openalex.org/I4210089612"]},{"raw_affiliation_string":"Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA","institution_ids":["https://openalex.org/I119942576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036441901","display_name":"Normita C. Bravo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089612","display_name":"United States Air Force","ror":"https://ror.org/006gmme17","country_code":"US","type":"government","lineage":["https://openalex.org/I1330347796","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Normita C. Bravo","raw_affiliation_strings":["Clinical Investigation Facility, Travis AFB, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Investigation Facility, Travis AFB, CA, USA","institution_ids":["https://openalex.org/I4210089612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068399737","display_name":"Holden Terry Maecker","orcid":"https://orcid.org/0000-0003-0795-9946","observed_orcids":["https://orcid.org/0000-0003-0795-9946","https://orcid.org/0000-0001-5389-0906"]},"institutions":[{"id":"https://openalex.org/I4210116987","display_name":"BD Biosciences (United States)","ror":"https://ror.org/02h9td068","country_code":"US","type":"company","lineage":["https://openalex.org/I146461966","https://openalex.org/I4210116987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Holden T. Maecker","raw_affiliation_strings":["Becton Dickinson Biosciences, San Jose, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Becton Dickinson Biosciences, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210116987"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101932146","display_name":"James W. Smith","orcid":"https://orcid.org/0000-0003-2986-8308","observed_orcids":["https://orcid.org/0000-0003-2986-8308"]},"institutions":[{"id":"https://openalex.org/I4210089612","display_name":"United States Air Force","ror":"https://ror.org/006gmme17","country_code":"US","type":"government","lineage":["https://openalex.org/I1330347796","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James W. Smith","raw_affiliation_strings":["Clinical Investigation Facility, Travis AFB, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Investigation Facility, Travis AFB, CA, USA","institution_ids":["https://openalex.org/I4210089612"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5023532953"],"corresponding_institution_ids":["https://openalex.org/I119942576","https://openalex.org/I4210089612"],"apc_list":{"value":2970,"currency":"USD","value_usd":2970},"apc_paid":null,"fwci":0.1149,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.44922469,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"282","issue":"1-2","first_page":"169","last_page":"174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anthrax-vaccine","display_name":"anthrax vaccine","score":0.9409999847412109},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8840000033378601},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9850000143051147},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cell-mediated-immunity","display_name":"cell-mediated immunity","score":0.8299999833106995},{"id":"https://openalex.org/keywords/whole-blood-stimulation","display_name":"whole blood stimulation","score":0.7039999961853027},{"id":"https://openalex.org/keywords/antigen-concentration","display_name":"antigen concentration","score":0.5},{"id":"https://openalex.org/keywords/vaccine-immunogenicity","display_name":"vaccine immunogenicity","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C2777289321","wikidata":"https://www.wikidata.org/wiki/Q4007170","display_name":"Anthrax vaccines","level":5,"score":0.8838015794754028},{"id":"https://openalex.org/C41810244","wikidata":"https://www.wikidata.org/wiki/Q1935986","display_name":"Anthrax toxin","level":5,"score":0.6171636581420898},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5700629949569702},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.5489405989646912},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.544503390789032},{"id":"https://openalex.org/C2780239966","wikidata":"https://www.wikidata.org/wiki/Q614156","display_name":"Bacillus anthracis","level":3,"score":0.5310502648353577},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49997639656066895},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.47355642914772034},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.4728829264640808},{"id":"https://openalex.org/C3017875465","wikidata":"https://www.wikidata.org/wiki/Q189146","display_name":"Cellular immunity","level":3,"score":0.4375686049461365},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.37577179074287415},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36385348439216614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3534872531890869},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.15362119674682617},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.0922461450099945},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.08287519216537476},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.06605076789855957},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C167508917","wikidata":"https://www.wikidata.org/wiki/Q578537","display_name":"DNA vaccination","level":4,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D022122","descriptor_name":"Anthrax Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jim.2003.07.012","doi":"https://doi.org/10.1016/j.jim.2003.07.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jim.2003.07.012","pdf_url":null,"source":{"id":"https://openalex.org/S201669150","display_name":"Journal of Immunological Methods","issn_l":"0022-1759","issn":["0022-1759","1872-7905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Immunological Methods","raw_type":"journal-article"},{"id":"pmid:14604550","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14604550","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunological methods","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W183575158","https://openalex.org/W1574561647","https://openalex.org/W1900009947","https://openalex.org/W2030226186","https://openalex.org/W2051510586","https://openalex.org/W2153293687","https://openalex.org/W4255260655","https://openalex.org/W6808394254"],"related_works":["https://openalex.org/W1991151519","https://openalex.org/W2124402246","https://openalex.org/W2158827509","https://openalex.org/W2081335127","https://openalex.org/W2154485350","https://openalex.org/W1977291876","https://openalex.org/W1983489319","https://openalex.org/W2038324655","https://openalex.org/W2081131456","https://openalex.org/W2044672740"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}