{"id":"https://openalex.org/W2069837962","doi":"https://doi.org/10.1016/j.ygcen.2007.01.046","title":"Regulation of vertebrate corticotropin-releasing factor genes","display_name":"Regulation of vertebrate corticotropin-releasing factor genes","publication_year":2007,"publication_date":"2007-02-18","ids":{"openalex":"https://openalex.org/W2069837962","doi":"https://doi.org/10.1016/j.ygcen.2007.01.046","mag":"2069837962","pmid":"https://pubmed.ncbi.nlm.nih.gov/17382944"},"language":"en","primary_location":{"id":"doi:10.1016/j.ygcen.2007.01.046","doi":"https://doi.org/10.1016/j.ygcen.2007.01.046","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ygcen.2007.01.046","pdf_url":null,"source":{"id":"https://openalex.org/S12418545","display_name":"General and Comparative Endocrinology","issn_l":"0016-6480","issn":["0016-6480","1095-6840"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General and Comparative Endocrinology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018916112","display_name":"Meng Yao","orcid":"https://orcid.org/0000-0002-8906-1461","observed_orcids":["https://orcid.org/0000-0002-8906-1461"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meng Yao","raw_affiliation_strings":["Department of Molecular, Cellular and Developmental Biology, 3065C Kraus Natural Science Building, The University of Michigan, Ann Arbor, MI 48109-1048, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular and Developmental Biology, 3065C Kraus Natural Science Building, The University of Michigan, Ann Arbor, MI 48109-1048, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069642074","display_name":"Robert J. Denver","orcid":"https://orcid.org/0000-0002-2773-8174","observed_orcids":["https://orcid.org/0000-0002-2773-8174"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert J. Denver","raw_affiliation_strings":["Department of Molecular, Cellular and Developmental Biology, 3065C Kraus Natural Science Building, The University of Michigan, Ann Arbor, MI 48109-1048, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular and Developmental Biology, 3065C Kraus Natural Science Building, The University of Michigan, Ann Arbor, MI 48109-1048, USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5069642074"],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":null,"fwci":0.6112,"has_fulltext":false,"cited_by_count":86,"citation_normalized_percentile":{"value":0.48387097,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"153","issue":"1-3","first_page":"200","last_page":"216"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":1.0},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.6449999809265137},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.8109999895095825},{"id":"https://openalex.org/keywords/glucocorticoid-feedback","display_name":"glucocorticoid feedback","score":0.9440000057220459},{"id":"https://openalex.org/keywords/crf-neurons","display_name":"CRF neurons","score":0.7070000171661377},{"id":"https://openalex.org/keywords/promoter-conservation","display_name":"promoter conservation","score":0.6570000052452087},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.9599999785423279},{"id":"https://openalex.org/keywords/creb","display_name":"CREB","score":0.953000009059906},{"id":"https://openalex.org/keywords/ap-1","display_name":"AP-1","score":0.8360000252723694},{"id":"https://openalex.org/keywords/nr4a1","display_name":"Nur77","score":0.9750000238418579},{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.9330000281333923},{"id":"https://openalex.org/keywords/mineralocorticoid-receptor","display_name":"mineralocorticoid receptor","score":0.996999979019165},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.6119999885559082},{"id":"https://openalex.org/keywords/comparative-genomics","display_name":"comparative genomics","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8567043542861938},{"id":"https://openalex.org/C2778458438","wikidata":"https://www.wikidata.org/wiki/Q386664","display_name":"Corticotropin-releasing hormone","level":3,"score":0.6857766509056091},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5845025777816772},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5681782960891724},{"id":"https://openalex.org/C1629964","wikidata":"https://www.wikidata.org/wiki/Q106950729","display_name":"CREB","level":4,"score":0.5296867489814758},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5208583474159241},{"id":"https://openalex.org/C59493245","wikidata":"https://www.wikidata.org/wiki/Q14877410","display_name":"Glucocorticoid receptor","level":3,"score":0.45352986454963684},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4308810830116272},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.4302057921886444},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4259885549545288},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.41012537479400635},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.38648393750190735},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.3755863606929779},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24924537539482117},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014714","descriptor_name":"Vertebrates","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.ygcen.2007.01.046","doi":"https://doi.org/10.1016/j.ygcen.2007.01.046","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ygcen.2007.01.046","pdf_url":null,"source":{"id":"https://openalex.org/S12418545","display_name":"General and Comparative Endocrinology","issn_l":"0016-6480","issn":["0016-6480","1095-6840"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General and Comparative Endocrinology","raw_type":"journal-article"},{"id":"pmid:17382944","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17382944","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General and comparative endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.322.6966","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.322.6966","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://labs.mcdb.lsa.umich.edu/labs/denver/files/publications/GCE accepted MS in press.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.326.7478","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.326.7478","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://labs.mcdb.lsa.umich.edu/labs/denver/files/publications/GCE 153,200.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.46810001134872437,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":227,"referenced_works":["https://openalex.org/W31659055","https://openalex.org/W181724490","https://openalex.org/W593103541","https://openalex.org/W1480394186","https://openalex.org/W1488901254","https://openalex.org/W1489982641","https://openalex.org/W1499904716","https://openalex.org/W1502038901","https://openalex.org/W1507132539","https://openalex.org/W1516514579","https://openalex.org/W1519700610","https://openalex.org/W1524779116","https://openalex.org/W1529415012","https://openalex.org/W1536241213","https://openalex.org/W1546774137","https://openalex.org/W1551136566","https://openalex.org/W1582869095","https://openalex.org/W1621971210","https://openalex.org/W1664096339","https://openalex.org/W1761323037","https://openalex.org/W1847582680","https://openalex.org/W1874620698","https://openalex.org/W1922807292","https://openalex.org/W1955229004","https://openalex.org/W1961661934","https://openalex.org/W1966407518","https://openalex.org/W1967015515","https://openalex.org/W1968199586","https://openalex.org/W1968815728","https://openalex.org/W1969974889","https://openalex.org/W1970764579","https://openalex.org/W1971482865","https://openalex.org/W1971639265","https://openalex.org/W1971840811","https://openalex.org/W1972692051","https://openalex.org/W1973235295","https://openalex.org/W1974381386","https://openalex.org/W1977130958","https://openalex.org/W1979753840","https://openalex.org/W1979881268","https://openalex.org/W1980664442","https://openalex.org/W1980722886","https://openalex.org/W1981101983","https://openalex.org/W1983633003","https://openalex.org/W1984638038","https://openalex.org/W1985112894","https://openalex.org/W1987557547","https://openalex.org/W1987892972","https://openalex.org/W1988855693","https://openalex.org/W1990034976","https://openalex.org/W1993812372","https://openalex.org/W1994590235","https://openalex.org/W1994699664","https://openalex.org/W1995289826","https://openalex.org/W1995865634","https://openalex.org/W1997510672","https://openalex.org/W2000768179","https://openalex.org/W2003148114","https://openalex.org/W2003337903","https://openalex.org/W2004716084","https://openalex.org/W2005344985","https://openalex.org/W2005730675","https://openalex.org/W2005833530","https://openalex.org/W2009229814","https://openalex.org/W2009757244","https://openalex.org/W2010001659","https://openalex.org/W2011184703","https://openalex.org/W2012613337","https://openalex.org/W2012681501","https://openalex.org/W2012718702","https://openalex.org/W2014485630","https://openalex.org/W2016200185","https://openalex.org/W2016950640","https://openalex.org/W2018211138","https://openalex.org/W2018919319","https://openalex.org/W2019101304","https://openalex.org/W2020492039","https://openalex.org/W2022605561","https://openalex.org/W2022743356","https://openalex.org/W2023929246","https://openalex.org/W2024837798","https://openalex.org/W2024848664","https://openalex.org/W2024978066","https://openalex.org/W2025433596","https://openalex.org/W2026453375","https://openalex.org/W2027145859","https://openalex.org/W2027478213","https://openalex.org/W2028139121","https://openalex.org/W2029081158","https://openalex.org/W2029117845","https://openalex.org/W2029263829","https://openalex.org/W2029696167","https://openalex.org/W2030745669","https://openalex.org/W2033059566","https://openalex.org/W2033690418","https://openalex.org/W2034116199","https://openalex.org/W2036304874","https://openalex.org/W2036475318","https://openalex.org/W2036479777","https://openalex.org/W2036994812","https://openalex.org/W2037034448","https://openalex.org/W2039839501","https://openalex.org/W2039844298","https://openalex.org/W2040324075","https://openalex.org/W2040465695","https://openalex.org/W2041736210","https://openalex.org/W2042950884","https://openalex.org/W2043176752","https://openalex.org/W2045378677","https://openalex.org/W2048429102","https://openalex.org/W2048701325","https://openalex.org/W2050246426","https://openalex.org/W2051080797","https://openalex.org/W2052854248","https://openalex.org/W2053089930","https://openalex.org/W2054143056","https://openalex.org/W2055806024","https://openalex.org/W2056386432","https://openalex.org/W2059686610","https://openalex.org/W2060309472","https://openalex.org/W2060644077","https://openalex.org/W2066947713","https://openalex.org/W2068165155","https://openalex.org/W2068246413","https://openalex.org/W2068412840","https://openalex.org/W2071489529","https://openalex.org/W2073905968","https://openalex.org/W2074215663","https://openalex.org/W2074244295","https://openalex.org/W2074483761","https://openalex.org/W2074716858","https://openalex.org/W2075378082","https://openalex.org/W2076200184","https://openalex.org/W2076411242","https://openalex.org/W2078146089","https://openalex.org/W2080184691","https://openalex.org/W2080440752","https://openalex.org/W2081264545","https://openalex.org/W2081973677","https://openalex.org/W2082225861","https://openalex.org/W2083773661","https://openalex.org/W2084219713","https://openalex.org/W2085124463","https://openalex.org/W2086945639","https://openalex.org/W2087366097","https://openalex.org/W2088359631","https://openalex.org/W2089512574","https://openalex.org/W2090451467","https://openalex.org/W2090645834","https://openalex.org/W2091228509","https://openalex.org/W2091497325","https://openalex.org/W2091811407","https://openalex.org/W2094481108","https://openalex.org/W2094640629","https://openalex.org/W2094772233","https://openalex.org/W2095036452","https://openalex.org/W2095395905","https://openalex.org/W2095491277","https://openalex.org/W2097483036","https://openalex.org/W2099851607","https://openalex.org/W2100027477","https://openalex.org/W2100969502","https://openalex.org/W2102578729","https://openalex.org/W2106372965","https://openalex.org/W2107638271","https://openalex.org/W2107866517","https://openalex.org/W2108212140","https://openalex.org/W2110385209","https://openalex.org/W2110657360","https://openalex.org/W2110955276","https://openalex.org/W2113994836","https://openalex.org/W2115759754","https://openalex.org/W2117313342","https://openalex.org/W2118089045","https://openalex.org/W2118434964","https://openalex.org/W2119725374","https://openalex.org/W2121576788","https://openalex.org/W2126904879","https://openalex.org/W2128569914","https://openalex.org/W2132539548","https://openalex.org/W2134323169","https://openalex.org/W2135070639","https://openalex.org/W2136709982","https://openalex.org/W2137280390","https://openalex.org/W2137385309","https://openalex.org/W2138115695","https://openalex.org/W2140471733","https://openalex.org/W2140661504","https://openalex.org/W2141246696","https://openalex.org/W2141682070","https://openalex.org/W2142940299","https://openalex.org/W2143241514","https://openalex.org/W2144042281","https://openalex.org/W2145827936","https://openalex.org/W2145906341","https://openalex.org/W2147277158","https://openalex.org/W2149097043","https://openalex.org/W2149651068","https://openalex.org/W2151531444","https://openalex.org/W2151785634","https://openalex.org/W2152043023","https://openalex.org/W2153646778","https://openalex.org/W2153932747","https://openalex.org/W2155234383","https://openalex.org/W2156629452","https://openalex.org/W2156736899","https://openalex.org/W2156753743","https://openalex.org/W2156827271","https://openalex.org/W2157398451","https://openalex.org/W2158853345","https://openalex.org/W2158871620","https://openalex.org/W2160305772","https://openalex.org/W2160692812","https://openalex.org/W2160881604","https://openalex.org/W2164948861","https://openalex.org/W2165787609","https://openalex.org/W2168540128","https://openalex.org/W2171238991","https://openalex.org/W2180410797","https://openalex.org/W2324523170","https://openalex.org/W2407468933","https://openalex.org/W2939382811","https://openalex.org/W4245933202","https://openalex.org/W4255304519","https://openalex.org/W4303105542","https://openalex.org/W6629326951","https://openalex.org/W7096054383"],"related_works":["https://openalex.org/W7100296309","https://openalex.org/W1979614696","https://openalex.org/W206880976","https://openalex.org/W2033293674","https://openalex.org/W1828536081","https://openalex.org/W1987892972","https://openalex.org/W2090085389","https://openalex.org/W2150734066","https://openalex.org/W1527247207","https://openalex.org/W1523275465"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}