{"id":"https://openalex.org/W2069813628","doi":"https://doi.org/10.1513/pats.200806-048lc","title":"Immunotherapy for Lung Cancer","display_name":"Immunotherapy for Lung Cancer","publication_year":2009,"publication_date":"2009-04-06","ids":{"openalex":"https://openalex.org/W2069813628","doi":"https://doi.org/10.1513/pats.200806-048lc","mag":"2069813628","pmid":"https://pubmed.ncbi.nlm.nih.gov/19349492"},"language":"en","primary_location":{"id":"doi:10.1513/pats.200806-048lc","doi":"https://doi.org/10.1513/pats.200806-048lc","is_oa":false,"landing_page_url":"https://doi.org/10.1513/pats.200806-048lc","pdf_url":null,"source":{"id":"https://openalex.org/S128617280","display_name":"Proceedings of the American Thoracic Society","issn_l":"1546-3222","issn":["1546-3222","1943-5665"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the American Thoracic Society","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111515203","display_name":"Edward A. Hirschowitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I2801012209","display_name":"Albert B. Chandler Hospital","ror":"https://ror.org/03r8nx235","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2801012209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. A. Hirschowitz","raw_affiliation_strings":["Department of Internal Medicine, University of Kentucky, Chandler Medical Center, Lexington, KY, USA. eahirs2@uky.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Kentucky, Chandler Medical Center, Lexington, KY, USA. eahirs2@uky.edu","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2801012209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109093980","display_name":"John R. Yannelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. R. Yannelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3034,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.92387066,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"2","first_page":"224","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9106000065803528,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9106000065803528,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0414000004529953,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.019200000911951065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.8019999861717224},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.9179999828338623},{"id":"https://openalex.org/keywords/antigen-specific-immune-response","display_name":"antigen-specific immune response","score":0.8600000143051147},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.5740000009536743},{"id":"https://openalex.org/keywords/early-stage-lung-cancer","display_name":"early-stage lung cancer","score":0.8019999861717224},{"id":"https://openalex.org/keywords/advanced-lung-cancer","display_name":"advanced lung cancer","score":0.8180000185966492},{"id":"https://openalex.org/keywords/disseminated-disease","display_name":"disseminated disease","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8815054893493652},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.7461888194084167},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5936789512634277},{"id":"https://openalex.org/C2780674031","wikidata":"https://www.wikidata.org/wiki/Q2012719","display_name":"Cancer immunotherapy","level":4,"score":0.5435781478881836},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4156385064125061},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4024029076099396},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35452669858932495},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.33417215943336487}],"mesh":[{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D015316","descriptor_name":"Genetic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1513/pats.200806-048lc","doi":"https://doi.org/10.1513/pats.200806-048lc","is_oa":false,"landing_page_url":"https://doi.org/10.1513/pats.200806-048lc","pdf_url":null,"source":{"id":"https://openalex.org/S128617280","display_name":"Proceedings of the American Thoracic Society","issn_l":"1546-3222","issn":["1546-3222","1943-5665"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the American Thoracic Society","raw_type":"journal-article"},{"id":"pmid:19349492","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19349492","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the American Thoracic Society","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W192002184","https://openalex.org/W1597238753","https://openalex.org/W1970533032","https://openalex.org/W1982395758","https://openalex.org/W1984484036","https://openalex.org/W1993561486","https://openalex.org/W2000786003","https://openalex.org/W2006334665","https://openalex.org/W2006909912","https://openalex.org/W2008858821","https://openalex.org/W2010457947","https://openalex.org/W2012800796","https://openalex.org/W2014956732","https://openalex.org/W2021896163","https://openalex.org/W2024111499","https://openalex.org/W2026102675","https://openalex.org/W2035698893","https://openalex.org/W2039461003","https://openalex.org/W2047127667","https://openalex.org/W2047902191","https://openalex.org/W2048084134","https://openalex.org/W2052409552","https://openalex.org/W2052892134","https://openalex.org/W2058676815","https://openalex.org/W2068837403","https://openalex.org/W2076819781","https://openalex.org/W2085962294","https://openalex.org/W2087057703","https://openalex.org/W2094637933","https://openalex.org/W2097191776","https://openalex.org/W2097989466","https://openalex.org/W2098958083","https://openalex.org/W2099122425","https://openalex.org/W2099597598","https://openalex.org/W2102537478","https://openalex.org/W2104967819","https://openalex.org/W2108348820","https://openalex.org/W2113316495","https://openalex.org/W2114300639","https://openalex.org/W2121505284","https://openalex.org/W2135284064","https://openalex.org/W2135674359","https://openalex.org/W2139819066","https://openalex.org/W2143458560","https://openalex.org/W2146571367","https://openalex.org/W2147996829","https://openalex.org/W2150380650","https://openalex.org/W2156763707","https://openalex.org/W2162819001","https://openalex.org/W2163919183","https://openalex.org/W2167284803","https://openalex.org/W2170549240","https://openalex.org/W2171127498","https://openalex.org/W2234552425","https://openalex.org/W2410313936"],"related_works":["https://openalex.org/W2035698893","https://openalex.org/W2143458560","https://openalex.org/W2116839451","https://openalex.org/W2347737489","https://openalex.org/W4321457619","https://openalex.org/W2035634354","https://openalex.org/W2509718500","https://openalex.org/W2014772370","https://openalex.org/W2104616589","https://openalex.org/W2005253379"],"abstract_inverted_index":{"Immunotherapy":[0],"is":[1,8,34,51],"a":[2,43,55],"conceptually":[3],"attractive":[4],"approach,":[5],"because":[6],"it":[7],"highly":[9],"specific":[10],"and":[11,69,86],"can":[12],"deal":[13],"with":[14,17,31],"disseminated":[15],"disease":[16],"minimal":[18],"impact":[19],"on":[20,83],"normal":[21],"tissues.":[22],"Ability":[23],"to":[24,53],"induce":[25],"antigen-specific":[26],"immune":[27],"responses":[28],"in":[29,38,66,94],"patients":[30],"lung":[32,71,95],"cancer":[33],"now":[35],"well":[36],"established":[37],"early-phase":[39],"clinical":[40,92],"trials":[41,93],"using":[42],"variety":[44],"of":[45,63,79,90],"immunotherapeutic":[46],"approaches.":[47],"Although":[48],"no":[49],"immunotherapy":[50],"likely":[52],"be":[54],"panacea,":[56],"randomized":[57],"phase":[58],"IIB":[59],"studies":[60],"offer":[61],"promise":[62],"therapeutic":[64],"activity":[65],"both":[67],"early-":[68],"late-stage":[70],"cancer.":[72,96],"This":[73],"review":[74],"will":[75],"cover":[76],"basic":[77],"concepts":[78],"immunotherapy,":[80],"provide":[81],"perspective":[82],"vaccine":[84],"development,":[85],"update":[87],"the":[88],"status":[89],"ongoing":[91]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}