{"id":"https://openalex.org/W2069727448","doi":"https://doi.org/10.1016/j.fitote.2005.07.009","title":"Asterosaponins from the starfish Culcita novaeguineae and their bioactivities","display_name":"Asterosaponins from the starfish Culcita novaeguineae and their bioactivities","publication_year":2005,"publication_date":"2005-10-20","ids":{"openalex":"https://openalex.org/W2069727448","doi":"https://doi.org/10.1016/j.fitote.2005.07.009","mag":"2069727448","pmid":"https://pubmed.ncbi.nlm.nih.gov/16242269"},"language":"en","primary_location":{"id":"doi:10.1016/j.fitote.2005.07.009","doi":"https://doi.org/10.1016/j.fitote.2005.07.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fitote.2005.07.009","pdf_url":null,"source":{"id":"https://openalex.org/S44811770","display_name":"Fitoterapia","issn_l":"0367-326X","issn":["0367-326X","1873-6971"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fitoterapia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060051967","display_name":"Hai\u2010Feng Tang","orcid":"https://orcid.org/0000-0002-9019-0260","observed_orcids":["https://orcid.org/0000-0002-9019-0260"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hai-Feng Tang","raw_affiliation_strings":["Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China. tanghaifeng71@126.com","Department of Pharmacy, Xijing Hospital, 4th Military Medical University, Xi'an 710032, PR China","Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China. tanghaifeng71@126.com","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Pharmacy, Xijing Hospital, 4th Military Medical University, Xi'an 710032, PR China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]},{"raw_affiliation_string":"Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113750283","display_name":"Yanghua Yi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang-Hua Yi","raw_affiliation_strings":["Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021445150","display_name":"Ling Li","orcid":"https://orcid.org/0000-0001-7394-2515","observed_orcids":["https://orcid.org/0000-0001-7394-2515"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ling Li","raw_affiliation_strings":["Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Peng Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Sun","raw_affiliation_strings":["Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Marine Drugs, College of Pharmacy, 2nd Military Medical University, Shanghai 200433, PR China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081554053","display_name":"San\u2010Qi Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"San-Qi Zhang","raw_affiliation_strings":["Department of Pharmacy, Xijing Hospital, 4th Military Medical University, Xi'an 710032, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Xijing Hospital, 4th Military Medical University, Xi'an 710032, PR China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084277718","display_name":"Zhao Yue-ping","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158926","display_name":"Xijing Hospital","ror":"https://ror.org/05cqe9350","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158926"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue-Ping Zhao","raw_affiliation_strings":["Department of Pharmacy, Xijing Hospital, 4th Military Medical University, Xi'an 710032, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Xijing Hospital, 4th Military Medical University, Xi'an 710032, PR China","institution_ids":["https://openalex.org/I4210158926","https://openalex.org/I9916479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5060051967"],"corresponding_institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210158926","https://openalex.org/I9916479"],"apc_list":{"value":3950,"currency":"USD","value_usd":3950},"apc_paid":null,"fwci":1.3329,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.75097616,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"77","issue":"1","first_page":"28","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.8119999766349792,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.8119999766349792,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":0.0997999981045723,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.04659999907016754,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asterosaponins","display_name":"asterosaponins","score":0.9829999804496765},{"id":"https://openalex.org/keywords/culcita-novaeguineae","display_name":"Culcita novaeguineae","score":0.9369999766349792},{"id":"https://openalex.org/keywords/sea-stars","display_name":"sea stars","score":0.921999990940094},{"id":"https://openalex.org/keywords/magnaporthe-oryzae","display_name":"Magnaporthe oryzae","score":0.953000009059906},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.890999972820282},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.984000027179718},{"id":"https://openalex.org/keywords/k562-cells","display_name":"K562 cells","score":0.9269999861717224},{"id":"https://openalex.org/keywords/bel-7402-cells","display_name":"BEL-7402 cells","score":0.9810000061988831},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C2778175403","wikidata":"https://www.wikidata.org/wiki/Q25349","display_name":"Starfish","level":2,"score":0.9265540838241577},{"id":"https://openalex.org/C2778312958","wikidata":"https://www.wikidata.org/wiki/Q7263583","display_name":"Pyricularia","level":2,"score":0.8698548078536987},{"id":"https://openalex.org/C104488531","wikidata":"https://www.wikidata.org/wiki/Q864212","display_name":"Bioassay","level":2,"score":0.7892125844955444},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.570961058139801},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5614724159240723},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.5355263948440552},{"id":"https://openalex.org/C2994372470","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell lines","level":4,"score":0.43488287925720215},{"id":"https://openalex.org/C133479454","wikidata":"https://www.wikidata.org/wiki/Q326228","display_name":"Mycelium","level":2,"score":0.42051640152931213},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3416905999183655},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26832666993141174},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.20921635627746582},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.1368037760257721},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.13199567794799805},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.13003304600715637},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001203","descriptor_name":"Ascomycota","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013215","descriptor_name":"Starfish","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013261","descriptor_name":"Sterols","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013261","descriptor_name":"Sterols","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013261","descriptor_name":"Sterols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018675","descriptor_name":"Toxicity Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.fitote.2005.07.009","doi":"https://doi.org/10.1016/j.fitote.2005.07.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fitote.2005.07.009","pdf_url":null,"source":{"id":"https://openalex.org/S44811770","display_name":"Fitoterapia","issn_l":"0367-326X","issn":["0367-326X","1873-6971"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fitoterapia","raw_type":"journal-article"},{"id":"pmid:16242269","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16242269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fitoterapia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W156287008","https://openalex.org/W1512378649","https://openalex.org/W1975232396","https://openalex.org/W2001268441","https://openalex.org/W2008071963","https://openalex.org/W2016131747","https://openalex.org/W2043666968","https://openalex.org/W2046740235","https://openalex.org/W2068553968","https://openalex.org/W2070674299","https://openalex.org/W2078424076","https://openalex.org/W2109689528","https://openalex.org/W2136174808","https://openalex.org/W2143220838","https://openalex.org/W2144326055","https://openalex.org/W2951855235"],"related_works":["https://openalex.org/W2042427577","https://openalex.org/W2074992304","https://openalex.org/W2372873756","https://openalex.org/W6902083125","https://openalex.org/W1975232396","https://openalex.org/W861061210","https://openalex.org/W2005014177","https://openalex.org/W3117722690","https://openalex.org/W2791692753","https://openalex.org/W3091540710"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}