{"id":"https://openalex.org/W2069658804","doi":"https://doi.org/10.1515/bchm2.1983.364.1.675","title":"The Primary Structure of Cu-Zn Superoxide Dismutase fromPhotobacterium leiognathi:Evidence for a Separate Evolution of Cu-Zn Superoxide Dismutase in Bacteria","display_name":"The Primary Structure of Cu-Zn Superoxide Dismutase fromPhotobacterium leiognathi:Evidence for a Separate Evolution of Cu-Zn Superoxide Dismutase in Bacteria","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W2069658804","doi":"https://doi.org/10.1515/bchm2.1983.364.1.675","mag":"2069658804","pmid":"https://pubmed.ncbi.nlm.nih.gov/6884993"},"language":"de","primary_location":{"id":"doi:10.1515/bchm2.1983.364.1.675","doi":"https://doi.org/10.1515/bchm2.1983.364.1.675","is_oa":false,"landing_page_url":"https://doi.org/10.1515/bchm2.1983.364.1.675","pdf_url":null,"source":{"id":"https://openalex.org/S4210203370","display_name":"Hoppe-Seyler\u00b4s Zeitschrift f\u00fcr physiologische Chemie","issn_l":"0018-4888","issn":["0018-4888"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hoppe-Seyler\u00b4s Zeitschrift f\u00fcr physiologische Chemie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068564856","display_name":"Gerd-J. Steffens","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerd-J. STEFFENS","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112400888","display_name":"Joseph V. Bannister","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph V. BANNISTER","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110668140","display_name":"William H. BANNISTER","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William H. BANNISTER","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008985143","display_name":"Leopold Floh\u00e9","orcid":"https://orcid.org/0000-0003-0940-8179","observed_orcids":["https://orcid.org/0000-0003-0940-8179"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Leopold FLOH\u00c9","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110147763","display_name":"Wolfgang A. G\u00fcnzler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wolfgang A. G\u00dcNZLER","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029115963","display_name":"Sung-Man A. Kim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sung-Man A. KIM","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5063769026","display_name":"Fritz \u00d6tting","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fritz \u00d6TTING","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.4073,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.99236641,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"364","issue":"1","first_page":"675","last_page":"690"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.5224999785423279,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.5224999785423279,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.34470000863075256,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.04690000042319298,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copper-zinc-superoxide-dismutase","display_name":"copper-zinc superoxide dismutase","score":0.9399999976158142},{"id":"https://openalex.org/keywords/photobacterium-leiognathi","display_name":"Photobacterium leiognathi","score":0.9980000257492065},{"id":"https://openalex.org/keywords/amino-acid-sequence","display_name":"amino acid sequence","score":0.7549999952316284},{"id":"https://openalex.org/keywords/sequence-homology","display_name":"sequence homology","score":0.6990000009536743},{"id":"https://openalex.org/keywords/phylogenetic-relationships","display_name":"phylogenetic relationships","score":0.800000011920929},{"id":"https://openalex.org/keywords/cysteine-residues","display_name":"cysteine residues","score":0.7900000214576721},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"horizontal gene transfer","score":0.8240000009536743}],"concepts":[{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.7647264003753662},{"id":"https://openalex.org/C87933860","wikidata":"https://www.wikidata.org/wiki/Q898506","display_name":"Edman degradation","level":4,"score":0.7155511379241943},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.6089320182800293},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5987134575843811},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5764274001121521},{"id":"https://openalex.org/C2778248901","wikidata":"https://www.wikidata.org/wiki/Q5282371","display_name":"Dismutase","level":4,"score":0.5674806833267212},{"id":"https://openalex.org/C92825506","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Protein primary structure","level":4,"score":0.5399904251098633},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.5268524885177612},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.47331273555755615},{"id":"https://openalex.org/C2777093645","wikidata":"https://www.wikidata.org/wiki/Q420258","display_name":"Cyanogen bromide","level":4,"score":0.460062175989151},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.43864524364471436},{"id":"https://openalex.org/C136398272","wikidata":"https://www.wikidata.org/wiki/Q83164201","display_name":"Carboxypeptidase A","level":4,"score":0.43184226751327515},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.41090795397758484},{"id":"https://openalex.org/C108477463","wikidata":"https://www.wikidata.org/wiki/Q426367","display_name":"Carboxypeptidase","level":3,"score":0.10748720169067383},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09983447194099426}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003488","descriptor_name":"Cyanogen Bromide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010776","descriptor_name":"Photobacterium","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D010776","descriptor_name":"Photobacterium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D013482","descriptor_name":"Superoxide Dismutase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014357","descriptor_name":"Trypsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1515/bchm2.1983.364.1.675","doi":"https://doi.org/10.1515/bchm2.1983.364.1.675","is_oa":false,"landing_page_url":"https://doi.org/10.1515/bchm2.1983.364.1.675","pdf_url":null,"source":{"id":"https://openalex.org/S4210203370","display_name":"Hoppe-Seyler\u00b4s Zeitschrift f\u00fcr physiologische Chemie","issn_l":"0018-4888","issn":["0018-4888"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hoppe-Seyler\u00b4s Zeitschrift f\u00fcr physiologische Chemie","raw_type":"journal-article"},{"id":"pmid:6884993","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6884993","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hoppe-Seyler's Zeitschrift fur physiologische Chemie","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1486447264","https://openalex.org/W1497458285","https://openalex.org/W1530287427","https://openalex.org/W1552672973","https://openalex.org/W1571793851","https://openalex.org/W1582776832","https://openalex.org/W1898798642","https://openalex.org/W1940436875","https://openalex.org/W2037913990","https://openalex.org/W2117966002","https://openalex.org/W2334665661","https://openalex.org/W2994028429"],"related_works":["https://openalex.org/W2079961662","https://openalex.org/W1530287427","https://openalex.org/W2213891900","https://openalex.org/W2040592121","https://openalex.org/W2048655025","https://openalex.org/W2312426324","https://openalex.org/W1982548068","https://openalex.org/W1591411915","https://openalex.org/W1582776832","https://openalex.org/W1987036719"],"abstract_inverted_index":{"The":[0,15,32,119],"complete":[1],"amino-acid":[2,89,104,225],"sequence":[3,49,150],"of":[4,9,40,56,64,76,80,91,106,140,148,159,180,190,224],"the":[5,10,28,65,77,87,92,102,107,131,135,141,157,176,181,202,207,222],"copper-zinc":[6],"superoxide":[7,84,96,171,192],"dismutase":[8,85,193],"Photobacterium":[11],"leiognathi":[12,161],"was":[13,35],"determined.":[14],"fragmentation":[16],"strategy":[17],"employed":[18],"included":[19],"cyanogen":[20],"bromide":[21],"cleavage":[22],"at":[23],"its":[24],"methionine":[25],"residues":[26,105,122],"and":[27,117,126,212],"only":[29,146,163],"tryptophan":[30],"residue.":[31],"S-carboxymethylated":[33],"chain":[34,67],"further":[36],"cleaved":[37],"by":[38],"means":[39],"trypsin,":[41],"in":[42,123,194],"order":[43],"to":[44,130,154,175,206],"obtain":[45],"overlapping":[46],"fragments.":[47],"For":[48],"determination":[50],"automated":[51],"solid":[52],"or":[53],"liquid-phase":[54],"techniques":[55],"Edman":[57],"degradation":[58],"were":[59,68,110,128,152],"used.":[60],"C-Terminal":[61],"amino":[62],"acids":[63],"entire":[66],"determined":[69],"after":[70],"treatment":[71],"with":[72,86],"carboxypeptidase":[73],"A.":[74],"Comparison":[75],"primary":[78],"structure":[79],"this":[81,185],"bacterial":[82],"Cu-Zn":[83,95,170,191],"established":[88,177],"sequences":[90],"other":[93],"eukaryotic":[94,169,203],"dismutases":[97],"revealed":[98],"clear":[99],"homologies.":[100],"Correspondingly,":[101],"Cu-Zn-binding":[103],"active":[108],"centre":[109],"localized:":[111],"His45,":[112],"His47,":[113],"His70,":[114],"His79,":[115],"His125":[116],"Asp91.":[118],"two":[120],"cysteine":[121,132],"position":[124],"52":[125],"147":[127],"homologous":[129],"residues,":[133],"modelling":[134],"essential":[136],"intrachain":[137],"disulfide":[138],"bridge":[139],"corresponding":[142],"bovine":[143],"enzyme.":[144],"As":[145],"25-30%":[147],"aligned":[149],"positions":[151],"found":[153],"be":[155,228],"identical,":[156],"enzyme":[158],"P.":[160],"shows":[162],"a":[164,187,197],"remote":[165],"phylogenetic":[166,178],"relationship":[167],"towards":[168],"dismutases.":[172],"When":[173],"compared":[174],"tree":[179],"cytochrome":[182],"c":[183],"family,":[184],"indicates":[186],"separate":[188],"evolution":[189],"Photobacterium.":[195],"Therefore,":[196],"natural":[198],"gene":[199],"transfer":[200],"from":[201],"host":[204],"(ponyfish)":[205],"prokaryotic":[208],"photobacterium,":[209],"which":[210],"Martin":[211],"Fridovich":[213],"postulated":[214],"1981":[215],"(J.":[216],"Biol.":[217],"Chem.":[218],"256,":[219],"6080-6089)":[220],"on":[221],"basis":[223],"compositions,":[226],"can":[227],"excluded.":[229]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}