{"id":"https://openalex.org/W2069494367","doi":"https://doi.org/10.1590/s0102-86502012000100007","title":"Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect","display_name":"Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect","publication_year":2011,"publication_date":"2011-12-08","ids":{"openalex":"https://openalex.org/W2069494367","doi":"https://doi.org/10.1590/s0102-86502012000100007","mag":"2069494367","pmid":"https://pubmed.ncbi.nlm.nih.gov/22159437"},"language":"en","primary_location":{"id":"doi:10.1590/s0102-86502012000100007","doi":"https://doi.org/10.1590/s0102-86502012000100007","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0102-86502012000100007","pdf_url":"https://www.scielo.br/j/acb/a/MSVHftdGfr4ThqrtgzrqJKp/?lang=en&format=pdf","source":{"id":"https://openalex.org/S44202665","display_name":"Acta Cir\u00fargica Brasileira","issn_l":"0102-8650","issn":["0102-8650","1678-2674"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312195","host_organization_name":"Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia","host_organization_lineage":["https://openalex.org/P4310312195"],"host_organization_lineage_names":["Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cirurgica Brasileira","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.scielo.br/j/acb/a/MSVHftdGfr4ThqrtgzrqJKp/?lang=en&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018424840","display_name":"Francisco Sobreira G. J\u00fanior","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Francisco Sobreira Guedes Jr","raw_affiliation_strings":["Experimental Laboratory of Anesthesiology, Botucatu School of Medicine, Sao Paulo State University (UNESP), Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Anesthesiology, Botucatu School of Medicine, Sao Paulo State University (UNESP), Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042596902","display_name":"Deyvid Santos da Cruz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Deyvid Santos da Cruz","raw_affiliation_strings":["I Fellow MSc degree, Postgraduate Program in Anesthesiology, UNESP, Brazil","n\u00e3o est\u00e3o envolvidas nessa prote\u00e7\u00e3o","Department of Anesthesiology, UNESP, Brazil","Faculdade de Medicina Botucatu-UNESP Depto. Anestesia Rubi\u00e3o J\u00fanior, s/n Caixa Postal 530 18618-970 Botucatu -SP Brasil","II Anestesiologist, UNESP, Brazil. Helped surgical procedures. III Fellow PhD degree, Postgraduate Program in Veterinary Medicine,","Postgraduate Program in Anesthesiology, UNESP, Brazil","UNESP, Brazil","Veterinary Medicine and Zootecny, UNESP, Brazil","por\u00e9m parece que TNF-\u03b1 e IL-"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Fellow MSc degree, Postgraduate Program in Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"n\u00e3o est\u00e3o envolvidas nessa prote\u00e7\u00e3o","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Faculdade de Medicina Botucatu-UNESP Depto. Anestesia Rubi\u00e3o J\u00fanior, s/n Caixa Postal 530 18618-970 Botucatu -SP Brasil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"II Anestesiologist, UNESP, Brazil. Helped surgical procedures. III Fellow PhD degree, Postgraduate Program in Veterinary Medicine,","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Postgraduate Program in Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Veterinary Medicine and Zootecny, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"por\u00e9m parece que TNF-\u03b1 e IL-","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039377047","display_name":"Marcela Marcondes Pinto Rodrigues","orcid":"https://orcid.org/0000-0002-9519-1756","observed_orcids":["https://orcid.org/0000-0002-9519-1756"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcela Marcondes Pinto Rodrigues","raw_affiliation_strings":["n\u00e3o est\u00e3o envolvidas nessa prote\u00e7\u00e3o","Department of Anesthesiology, UNESP, Brazil","Faculdade de Medicina Botucatu-UNESP Depto. Anestesia Rubi\u00e3o J\u00fanior, s/n Caixa Postal 530 18618-970 Botucatu -SP Brasil","I Fellow MSc degree, Postgraduate Program in Anesthesiology, UNESP, Brazil","II Anestesiologist, UNESP, Brazil. Helped surgical procedures. III Fellow PhD degree, Postgraduate Program in Veterinary Medicine,","Postgraduate Program in Anesthesiology, UNESP, Brazil","UNESP, Brazil","Veterinary Medicine and Zootecny, UNESP, Brazil","por\u00e9m parece que TNF-\u03b1 e IL-"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"n\u00e3o est\u00e3o envolvidas nessa prote\u00e7\u00e3o","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Faculdade de Medicina Botucatu-UNESP Depto. Anestesia Rubi\u00e3o J\u00fanior, s/n Caixa Postal 530 18618-970 Botucatu -SP Brasil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"I Fellow MSc degree, Postgraduate Program in Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"II Anestesiologist, UNESP, Brazil. Helped surgical procedures. III Fellow PhD degree, Postgraduate Program in Veterinary Medicine,","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Postgraduate Program in Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Veterinary Medicine and Zootecny, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"por\u00e9m parece que TNF-\u03b1 e IL-","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024123345","display_name":"Leopoldo Muniz da Silva","orcid":"https://orcid.org/0000-0003-4703-0832","observed_orcids":["https://orcid.org/0000-0003-4703-0832"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Leopoldo Muniz da Silva","raw_affiliation_strings":["n\u00e3o est\u00e3o envolvidas nessa prote\u00e7\u00e3o","Department of Anesthesiology, UNESP, Brazil","Faculdade de Medicina Botucatu-UNESP Depto. Anestesia Rubi\u00e3o J\u00fanior, s/n Caixa Postal 530 18618-970 Botucatu -SP Brasil","I Fellow MSc degree, Postgraduate Program in Anesthesiology, UNESP, Brazil","II Anestesiologist, UNESP, Brazil. Helped surgical procedures. III Fellow PhD degree, Postgraduate Program in Veterinary Medicine,","Postgraduate Program in Anesthesiology, UNESP, Brazil","UNESP, Brazil","Veterinary Medicine and Zootecny, UNESP, Brazil","por\u00e9m parece que TNF-\u03b1 e IL-"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"n\u00e3o est\u00e3o envolvidas nessa prote\u00e7\u00e3o","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Faculdade de Medicina Botucatu-UNESP Depto. Anestesia Rubi\u00e3o J\u00fanior, s/n Caixa Postal 530 18618-970 Botucatu -SP Brasil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"I Fellow MSc degree, Postgraduate Program in Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"II Anestesiologist, UNESP, Brazil. Helped surgical procedures. III Fellow PhD degree, Postgraduate Program in Veterinary Medicine,","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Postgraduate Program in Anesthesiology, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Veterinary Medicine and Zootecny, UNESP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"por\u00e9m parece que TNF-\u03b1 e IL-","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079689787","display_name":"Ren\u00e9e Laufer Amorim","orcid":"https://orcid.org/0000-0002-8653-7938","observed_orcids":["https://orcid.org/0000-0002-8653-7938"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ren\u00e9e Laufer Amorim","raw_affiliation_strings":["Unesp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unesp","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108684269","display_name":"Pedro Thadeu Galv\u00e3o Vianna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Pedro Thadeu Galv\u00e3o Vianna","raw_affiliation_strings":["Unesp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unesp","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000231264","display_name":"Yara Marcondes Machado Castiglia","orcid":"https://orcid.org/0000-0003-1904-3695","observed_orcids":["https://orcid.org/0000-0003-1904-3695"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Yara Marcondes Machado Castiglia","raw_affiliation_strings":["Unesp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unesp","institution_ids":["https://openalex.org/I879563668"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000231264"],"corresponding_institution_ids":["https://openalex.org/I879563668"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":0.2431,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.61329732,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"27","issue":"1","first_page":"37","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sevoflurane","display_name":"sevoflurane","score":0.875},{"id":"https://openalex.org/keywords/ketoprofen","display_name":"ketoprofen","score":1.0},{"id":"https://openalex.org/keywords/acute-hemorrhage","display_name":"acute hemorrhage","score":0.6970000267028809},{"id":"https://openalex.org/keywords/hypovolemia","display_name":"hypovolemia","score":0.8309999704360962},{"id":"https://openalex.org/keywords/renal-protection","display_name":"renal protection","score":0.6320000290870667},{"id":"https://openalex.org/keywords/tubular-necrosis","display_name":"tubular necrosis","score":0.800000011920929},{"id":"https://openalex.org/keywords/hypothermia","display_name":"hypothermia","score":0.7160000205039978},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8980000019073486},{"id":"https://openalex.org/keywords/interleukin-1","display_name":"interleukin-1","score":1.0},{"id":"https://openalex.org/keywords/cyclooxygenase-inhibitors","display_name":"cyclooxygenase inhibitors","score":0.843999981880188},{"id":"https://openalex.org/keywords/anesthesia","display_name":"anesthesia","score":0.31700000166893005},{"id":"https://openalex.org/keywords/kidney-histology","display_name":"kidney histology","score":0.6290000081062317},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.5899999737739563}],"concepts":[{"id":"https://openalex.org/C2781453256","wikidata":"https://www.wikidata.org/wiki/Q419394","display_name":"Sevoflurane","level":2,"score":0.8570394515991211},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8120262622833252},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6614042520523071},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.5795639753341675},{"id":"https://openalex.org/C2780744026","wikidata":"https://www.wikidata.org/wiki/Q409192","display_name":"Ketoprofen","level":2,"score":0.5433043837547302},{"id":"https://openalex.org/C2777019824","wikidata":"https://www.wikidata.org/wiki/Q417915","display_name":"Sufentanil","level":2,"score":0.5073563456535339},{"id":"https://openalex.org/C2780227381","wikidata":"https://www.wikidata.org/wiki/Q1357376","display_name":"Nephrectomy","level":3,"score":0.503269374370575},{"id":"https://openalex.org/C2776452961","wikidata":"https://www.wikidata.org/wiki/Q1940733","display_name":"Mean arterial pressure","level":4,"score":0.49965858459472656},{"id":"https://openalex.org/C2780149897","wikidata":"https://www.wikidata.org/wiki/Q216935","display_name":"Lidocaine","level":2,"score":0.4647606611251831},{"id":"https://openalex.org/C2776277131","wikidata":"https://www.wikidata.org/wiki/Q422740","display_name":"Propofol","level":2,"score":0.4573724567890167},{"id":"https://openalex.org/C2778891214","wikidata":"https://www.wikidata.org/wiki/Q417902","display_name":"Remifentanil","level":3,"score":0.42003798484802246},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.41518503427505493},{"id":"https://openalex.org/C2777094939","wikidata":"https://www.wikidata.org/wiki/Q1368943","display_name":"Intracerebral hemorrhage","level":3,"score":0.4104359447956085},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.34818074107170105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.221760094165802},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1753053367137909},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.06585967540740967},{"id":"https://openalex.org/C2777736543","wikidata":"https://www.wikidata.org/wiki/Q693442","display_name":"Subarachnoid hemorrhage","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000077149","descriptor_name":"Sevoflurane","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007660","descriptor_name":"Ketoprofen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D008738","descriptor_name":"Methyl Ethers","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016861","descriptor_name":"Cyclooxygenase Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018685","descriptor_name":"Anesthetics, Inhalation","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1590/s0102-86502012000100007","doi":"https://doi.org/10.1590/s0102-86502012000100007","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0102-86502012000100007","pdf_url":"https://www.scielo.br/j/acb/a/MSVHftdGfr4ThqrtgzrqJKp/?lang=en&format=pdf","source":{"id":"https://openalex.org/S44202665","display_name":"Acta Cir\u00fargica Brasileira","issn_l":"0102-8650","issn":["0102-8650","1678-2674"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312195","host_organization_name":"Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia","host_organization_lineage":["https://openalex.org/P4310312195"],"host_organization_lineage_names":["Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cirurgica Brasileira","raw_type":"journal-article"},{"id":"pmid:22159437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22159437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta cirurgica brasileira","raw_type":"Journal Article"},{"id":"pmh:oai:repositorio.unesp.br:11449/10902","doi":null,"is_oa":true,"landing_page_url":"http://doi.org/10.1590/S0102-86502012000100007","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UNESP","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:scielo:S0102-86502012000100007","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000100007","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cir\u00fargica Brasileira v.27 n.1 2012","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:acervodigital.unesp.br:11449/10902","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/10902","pdf_url":null,"source":{"id":"https://openalex.org/S4306400256","display_name":"Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115194","host_organization_name":"Funda\u00e7\u00e3o para o Desenvolvimento da UNESP","host_organization_lineage":["https://openalex.org/I4210115194"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"outro"},{"id":"pmh:oai:americanae.aecid.es:1706965","doi":null,"is_oa":true,"landing_page_url":"http://americanae.aecid.es/americanae/es/registros/registro.do?tipoRegistro=MTD&idBib=1706965","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UNESP","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2495928","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000100007","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Cirurgica Brasileira v.27 n.1 2012","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:845a61855d6d4f7a83d4d355ed7b33ae","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/845a61855d6d4f7a83d4d355ed7b33ae","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Cir\u00fargica Brasileira, Vol 27, Iss 1, Pp 37-42 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1590/s0102-86502012000100007","doi":"https://doi.org/10.1590/s0102-86502012000100007","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0102-86502012000100007","pdf_url":"https://www.scielo.br/j/acb/a/MSVHftdGfr4ThqrtgzrqJKp/?lang=en&format=pdf","source":{"id":"https://openalex.org/S44202665","display_name":"Acta Cir\u00fargica Brasileira","issn_l":"0102-8650","issn":["0102-8650","1678-2674"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312195","host_organization_name":"Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia","host_organization_lineage":["https://openalex.org/P4310312195"],"host_organization_lineage_names":["Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cirurgica Brasileira","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2069494367.pdf","grobid_xml":"https://content.openalex.org/works/W2069494367.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1964661223","https://openalex.org/W2013371338","https://openalex.org/W2014748042","https://openalex.org/W2021839146","https://openalex.org/W2027084180","https://openalex.org/W2035937533","https://openalex.org/W2054744541","https://openalex.org/W2056879548","https://openalex.org/W2065434132","https://openalex.org/W2069722312","https://openalex.org/W2116931614","https://openalex.org/W2129517912","https://openalex.org/W2399901582","https://openalex.org/W2412121469","https://openalex.org/W4236514815"],"related_works":["https://openalex.org/W7038088082","https://openalex.org/W7099496241","https://openalex.org/W2129517912","https://openalex.org/W2146874467","https://openalex.org/W781304069","https://openalex.org/W2164073143","https://openalex.org/W2380288292","https://openalex.org/W2042956454","https://openalex.org/W838916302","https://openalex.org/W2350678749"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"investigate":[2],"the":[3,76,95,99,151,162],"influence":[4],"of":[5,29,31,37,78,88,153,167],"intravenous":[6],"nonselective":[7],"cyclooxygenase":[8],"inhibitor,":[9],"ketoprofen":[10],"(keto),":[11],"on":[12],"kidney":[13,17,164],"histological":[14],"changes":[15],"and":[16,23,48,62,90,103,115,122,171,178],"cytokines,":[18],"tumor":[19],"necrosis":[20,136],"factor-\u03b1":[21],"(TNF-\u03b1)":[22],"interleukin-1":[24],"(IL-1),":[25],"levels":[26],"after":[27,106],"hemorrhage":[28,97,101],"30%":[30],"volemia":[32],"(three":[33],"times":[34],"10%,":[35],"intervals":[36],"10":[38],"min)":[39],"in":[40,72,75,131,140,150,165,183],"rats.":[41],"METHODS:":[42],"Under":[43],"sevoflurane":[44,170],"(sevo)":[45],"anesthesia,":[46],"sevo":[47,132,141],"sevo+keto":[49,73],"groups":[50],"(10":[51],"rats":[52],"each)":[53],"were":[54,92,147,180],"instrumented":[55],"for":[56,113],"Ringer":[57],"solution":[58],"(5":[59],"mL/kg/h)":[60],"administration":[61,71],"mean":[63],"arterial":[64],"pressure":[65],"(MAP)":[66],"evaluation,":[67],"plus":[68],"keto":[69],"(1.5mg/kg)":[70],"group":[74,133,142],"beginning":[77],"anesthesia.":[79],"Rectal":[80],"temperature":[81,89,121],"was":[82,111,129,137,158],"continuously":[83],"measured.":[84],"The":[85,144],"baseline":[86],"data":[87],"MAP":[91,123],"collected":[93],"at":[94],"first":[96],"(T1),":[98],"third":[100],"(T2)":[102],"30":[104],"min":[105],"T2":[107],"(T3).":[108],"Bilateral":[109],"nephrectomy":[110],"achieved":[112],"histology":[114],"immunohistochemistry.":[116],"RESULTS:":[117],"In":[118],"both":[119,154],"groups,":[120],"diminished":[124],"from":[125],"initial":[126],"values.":[127],"Hypothermia":[128],"greater":[130],"(p=0.0002).":[134],"Tubular":[135],"more":[138,159],"frequent":[139],"(p=0.02).":[143],"studied":[145],"cytokines":[146],"equally":[148],"present":[149],"kidneys":[152],"groups.":[155],"CONCLUSION:":[156],"Ketoprofen":[157],"protective":[160],"to":[161],"rat":[163],"condition":[166],"anesthesia":[168],"with":[169],"hypovolemia,":[172],"but":[173],"it":[174],"seems":[175],"that":[176,184],"TNF-\u03b1":[177],"IL-1":[179],"not":[181],"involved":[182],"protection.":[185]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}