{"id":"https://openalex.org/W2069362001","doi":"https://doi.org/10.1111/j.1471-0528.2000.tb13242.x","title":"Hyperechogenic fetal bowel: a prospective analysis of sixty consecutive cases","display_name":"Hyperechogenic fetal bowel: a prospective analysis of sixty consecutive cases","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2069362001","doi":"https://doi.org/10.1111/j.1471-0528.2000.tb13242.x","mag":"2069362001","pmid":"https://pubmed.ncbi.nlm.nih.gov/10740343"},"language":"en","primary_location":{"id":"doi:10.1111/j.1471-0528.2000.tb13242.x","doi":"https://doi.org/10.1111/j.1471-0528.2000.tb13242.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1471-0528.2000.tb13242.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210173111","display_name":"BJOG An International Journal of Obstetrics & Gynaecology","issn_l":"0306-5456","issn":["0306-5456","1365-215X","1470-0328","1471-0528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BJOG: An International Journal of Obstetrics & Gynaecology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018757968","display_name":"Ishika Ghose","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ishika Ghose","raw_affiliation_strings":["Department of Fetal Medicine, The Leeds Teaching Hospitals NHS Trust, UK","Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fetal Medicine, The Leeds Teaching Hospitals NHS Trust, UK","institution_ids":["https://openalex.org/I2799390153"]},{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084494844","display_name":"Gerald Mason","orcid":"https://orcid.org/0000-0003-0389-3986","observed_orcids":["https://orcid.org/0000-0003-0389-3986"]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gerald C. Mason","raw_affiliation_strings":["Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112166825","display_name":"Delia Martinez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Delia Martinez","raw_affiliation_strings":["Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Karen L. Harrison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Karen L. Harrison","raw_affiliation_strings":["Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070846162","display_name":"Janet Evans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Anthony Evans","raw_affiliation_strings":["Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062293653","display_name":"Emma L. Ferriman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emma L. Ferriman","raw_affiliation_strings":["Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031838417","display_name":"Mark David Stringer","orcid":"https://orcid.org/0000-0003-3024-7971","observed_orcids":["https://orcid.org/0000-0003-3024-7971","https://orcid.org/0000-0003-2102-1049"]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark D. Stringer","raw_affiliation_strings":["Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Fetal Medicine, Paediatric Surgery, Radiology and Medical Physics, The Leeds Teaching Hospitals NHS Trust, Leeds","institution_ids":["https://openalex.org/I2799390153"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2799390153"],"apc_list":{"value":5190,"currency":"USD","value_usd":5190},"apc_paid":null,"fwci":3.1499,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.91022866,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"107","issue":"3","first_page":"426","last_page":"429"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12716","display_name":"Congenital Anomalies and Fetal Surgery","score":0.012900000438094139,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/second-trimester-ultrasound","display_name":"second-trimester ultrasound","score":0.7369999885559082},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.8500000238418579},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.972000002861023},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.9419999718666077},{"id":"https://openalex.org/keywords/perinatal-outcomes","display_name":"perinatal outcomes","score":0.7860000133514404},{"id":"https://openalex.org/keywords/prenatal-diagnosis","display_name":"prenatal diagnosis","score":0.6800000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8277647495269775},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.726293683052063},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.6544106602668762},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6243026852607727},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6144760251045227},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.6100306510925293},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.534096896648407},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5031368136405945},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.41889724135398865},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2866850197315216},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09608215093612671},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000028","descriptor_name":"Abortion, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003550","descriptor_name":"Cystic Fibrosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016216","descriptor_name":"Ultrasonography, Prenatal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1471-0528.2000.tb13242.x","doi":"https://doi.org/10.1111/j.1471-0528.2000.tb13242.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1471-0528.2000.tb13242.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210173111","display_name":"BJOG An International Journal of Obstetrics & Gynaecology","issn_l":"0306-5456","issn":["0306-5456","1365-215X","1470-0328","1471-0528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BJOG: An International Journal of Obstetrics & Gynaecology","raw_type":"journal-article"},{"id":"pmid:10740343","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10740343","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BJOG : an international journal of obstetrics and gynaecology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W19647169","https://openalex.org/W1977011610","https://openalex.org/W1991999144","https://openalex.org/W2004783207","https://openalex.org/W2074127317","https://openalex.org/W2076125530","https://openalex.org/W2101774927","https://openalex.org/W2127346474","https://openalex.org/W2141088504","https://openalex.org/W2153270360","https://openalex.org/W2441988029"],"related_works":["https://openalex.org/W2032698886","https://openalex.org/W2011137968","https://openalex.org/W2398789605","https://openalex.org/W2033210624","https://openalex.org/W19647169","https://openalex.org/W2127346474","https://openalex.org/W2163535920","https://openalex.org/W4295773264","https://openalex.org/W2141088504","https://openalex.org/W1977011610"],"abstract_inverted_index":{"A":[0],"two":[1,83],"year":[2],"prospective":[3],"analysis":[4],"of":[5,12,30,40,58,65,89,102,115,121],"all":[6],"second":[7],"trimester":[8],"fetuses":[9,42,62,112,122],"(16-22":[10],"weeks":[11],"gestation)":[13],"with":[14,77,124],"hyperechogenic":[15,126],"bowel":[16,21,127],"was":[17,34,43,108],"undertaken.":[18],"Hyperechogenic":[19],"fetal":[20,32,80],"(sonographic":[22],"echogenicity":[23],"similar":[24],"to":[25,55],"or":[26],"greater":[27],"than":[28],"that":[29],"surrounding":[31],"bone)":[33],"diagnosed":[35],"using":[36],"strict":[37],"criteria.":[38],"Outcome":[39],"affected":[41],"ascertained":[44],"from":[45],"hospital":[46],"records,":[47],"health":[48],"care":[49],"workers":[50],"and":[51,82,92,97],"autopsy":[52],"reports,":[53],"up":[54],"six":[56,111],"months":[57],"age.":[59],"Sixty":[60],"consecutive":[61],"were":[63,69,73,94,99],"identified,":[64],"which":[66],"48":[67],"(80%)":[68],"liveborn.":[70],"Six":[71],"pregnancies":[72],"terminated,":[74],"four":[75,114],"ended":[76],"an":[78],"intrauterine":[79],"death":[81],"died":[84,117],"at":[85],"birth.":[86],"The":[87],"incidence":[88],"cystic":[90],"fibrosis":[91],"aneuploidy":[93],"each":[95],"5%,":[96],"there":[98],"no":[100],"cases":[101],"congenital":[103],"infection.":[104],"Intrauterine":[105],"growth":[106],"retardation":[107],"recorded":[109],"in":[110],"(10%),":[113],"whom":[116],"perinatally.":[118],"Eighty-two":[119],"percent":[120],"(28/34)":[123],"isolated":[125],"had":[128],"a":[129],"normal":[130],"outcome.":[131]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}