{"id":"https://openalex.org/W2068941192","doi":"https://doi.org/10.1084/jem.138.4.798","title":"TWO DIFFERENT COMPLEMENT RECEPTORS ON HUMAN LYMPHOCYTES","display_name":"TWO DIFFERENT COMPLEMENT RECEPTORS ON HUMAN LYMPHOCYTES","publication_year":1973,"publication_date":"1973-10-01","ids":{"openalex":"https://openalex.org/W2068941192","doi":"https://doi.org/10.1084/jem.138.4.798","mag":"2068941192","pmid":"https://pubmed.ncbi.nlm.nih.gov/4542735","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2180565"},"language":"en","primary_location":{"id":"doi:10.1084/jem.138.4.798","doi":"https://doi.org/10.1084/jem.138.4.798","is_oa":false,"landing_page_url":"https://doi.org/10.1084/jem.138.4.798","pdf_url":null,"source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2180565","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111446242","display_name":"Gordon D. Ross","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon D. Ross","raw_affiliation_strings":["From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112028804","display_name":"Margaret J. Polley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret J. Polley","raw_affiliation_strings":["From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108362075","display_name":"Enrique M. Rabellino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Enrique M. Rabellino","raw_affiliation_strings":["From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I3019586173"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110101301","display_name":"Howard M. Grey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Howard M. Grey","raw_affiliation_strings":["From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Cornell University Medical College, New York 10021, and the National Jewish Hospital and Research Center, Denver, Colorado 80206","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I3019586173"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":13.0249,"has_fulltext":false,"cited_by_count":282,"citation_normalized_percentile":{"value":0.99434309,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"138","issue":"4","first_page":"798","last_page":"811"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/complement-receptors","display_name":"complement receptors","score":0.972000002861023},{"id":"https://openalex.org/keywords/complement-c3b-receptor","display_name":"C3b receptor","score":0.9039999842643738},{"id":"https://openalex.org/keywords/c3b-inactivator","display_name":"C3b inactivator","score":0.8320000171661377},{"id":"https://openalex.org/keywords/lymphocytes","display_name":"lymphocytes","score":0.75},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.9549999833106995},{"id":"https://openalex.org/keywords/lymphoblastoid-cell-lines","display_name":"lymphoblastoid cell lines","score":0.9160000085830688},{"id":"https://openalex.org/keywords/granulocytes","display_name":"granulocytes","score":0.8299999833106995},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.9520000219345093},{"id":"https://openalex.org/keywords/complement-system","display_name":"complement system","score":0.4440000057220459}],"concepts":[{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.7642695307731628},{"id":"https://openalex.org/C103474210","wikidata":"https://www.wikidata.org/wiki/Q142851","display_name":"Immune receptor","level":3,"score":0.7075947523117065},{"id":"https://openalex.org/C2778212101","wikidata":"https://www.wikidata.org/wiki/Q6005426","display_name":"Immune adherence","level":4,"score":0.6515887379646301},{"id":"https://openalex.org/C175773311","wikidata":"https://www.wikidata.org/wiki/Q5156412","display_name":"Complement receptor","level":4,"score":0.6470944285392761},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5759397745132446},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5251666903495789},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.521704375743866},{"id":"https://openalex.org/C91523082","wikidata":"https://www.wikidata.org/wiki/Q420496","display_name":"Antiserum","level":3,"score":0.4103371798992157},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3862196207046509},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.341298371553421},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.3279913067817688},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11113113164901733},{"id":"https://openalex.org/C34343649","wikidata":"https://www.wikidata.org/wiki/Q1548862","display_name":"Hemagglutination","level":3,"score":0.08059683442115784}],"mesh":[{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003165","descriptor_name":"Complement System Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007104","descriptor_name":"Immune Adherence Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007945","descriptor_name":"Leukemia, Lymphoid","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1084/jem.138.4.798","doi":"https://doi.org/10.1084/jem.138.4.798","is_oa":false,"landing_page_url":"https://doi.org/10.1084/jem.138.4.798","pdf_url":null,"source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Experimental Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2180565","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2180565","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmid:4542735","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4542735","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Comparative Study"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2180565","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2180565","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W256767045","https://openalex.org/W1488807000","https://openalex.org/W1489163481","https://openalex.org/W1500149238","https://openalex.org/W1517689701","https://openalex.org/W1544793479","https://openalex.org/W1699994558","https://openalex.org/W1753791163","https://openalex.org/W1835506423","https://openalex.org/W1898101441","https://openalex.org/W1972625982","https://openalex.org/W1974498209","https://openalex.org/W1988189740","https://openalex.org/W1995252281","https://openalex.org/W2004870869","https://openalex.org/W2018932922","https://openalex.org/W2024976324","https://openalex.org/W2035678622","https://openalex.org/W2051517008","https://openalex.org/W2062276015","https://openalex.org/W2078849705","https://openalex.org/W2079580780","https://openalex.org/W2090007108","https://openalex.org/W2107549694","https://openalex.org/W2126818684","https://openalex.org/W2145163419","https://openalex.org/W2620799180"],"related_works":["https://openalex.org/W7097947113","https://openalex.org/W2061484723","https://openalex.org/W7099316514","https://openalex.org/W1487190732","https://openalex.org/W4323254862","https://openalex.org/W1794790173","https://openalex.org/W7100624305","https://openalex.org/W2007997507","https://openalex.org/W1940430792","https://openalex.org/W46022911"],"abstract_inverted_index":{"IN":[0],"THE":[1],"PRESENT":[2],"STUDY":[3],"IT":[4],"WAS":[5],"SHOWN":[6],"THAT":[7],"NORMAL":[8],"PERIPHERAL":[9],"LYMPHOCYTES":[10],"HAVE":[11],"TWO":[12],"DIFFERENT":[13],"COMPLEMENT":[14],"RECEPTORS:":[15],"one":[16,24],"for":[17,25,60,102,134,142],"C3b":[18,26,32,61,63,103,105,135,143],"(the":[19],"immune":[20,54,85,120],"adherence":[21,55,86,121],"receptor)":[22],"and":[23,40,57,70,136],"subsequent":[27],"to":[28,48,116,129],"its":[29],"cleavage":[30],"by":[31,43],"inactivator.":[33],"The":[34],"two":[35],"receptors":[36],"are":[37],"not":[38,138],"cross-reactive":[39],"were":[41,64,114],"shown":[42],"tests":[44],"with":[45],"various":[46],"antisera":[47],"be":[49],"antigenically":[50],"distinct.":[51],"Both":[52],"the":[53,58,84,95,99,111,119],"receptor":[56,59,87,101,133,141],"inactivator-cleaved":[62,104,144],"found":[65,115],"on":[66,71,110],"normal":[67,125],"peripheral":[68,96,126],"lymphocytes":[69],"cultured":[72],"lymphoblastoid":[73],"cells.":[74],"In":[75],"15":[76],"out":[77],"of":[78],"18":[79],"chronic":[80],"lymphatic":[81],"leukemia":[82],"patients,":[83],"was":[88,106],"either":[89],"partially":[90],"or":[91],"completely":[92],"missing":[93],"from":[94,124],"lymphocytes,":[97],"while":[98],"lymphocyte":[100],"retained.":[107],"Normal":[108],"erythrocytes,":[109],"other":[112],"hand,":[113],"have":[117,130,139],"only":[118,131],"receptor.":[122],"Granulocytes":[123],"blood":[127],"appeared":[128],"a":[132,140],"did":[137],"C3b.":[145]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}