{"id":"https://openalex.org/W2068625834","doi":"https://doi.org/10.1111/age.12190","title":"Mutation in the protease cleavage site of GDF 9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes","display_name":"Mutation in the protease cleavage site of GDF 9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes","publication_year":2014,"publication_date":"2014-07-14","ids":{"openalex":"https://openalex.org/W2068625834","doi":"https://doi.org/10.1111/age.12190","mag":"2068625834","pmid":"https://pubmed.ncbi.nlm.nih.gov/25039891"},"language":"en","primary_location":{"id":"doi:10.1111/age.12190","doi":"https://doi.org/10.1111/age.12190","is_oa":true,"landing_page_url":"https://doi.org/10.1111/age.12190","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/age.12190","source":{"id":"https://openalex.org/S12146737","display_name":"Animal Genetics","issn_l":"0268-9146","issn":["0268-9146","1365-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Genetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/age.12190","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080405012","display_name":"C. J. H. de Souza","orcid":"https://orcid.org/0000-0003-3886-2020","observed_orcids":["https://orcid.org/0000-0003-3886-2020"]},"institutions":[{"id":"https://openalex.org/I4405285346","display_name":"Embrapa Pecu\u00e1ria Sul","ror":"https://ror.org/058j9ky09","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"C. J. H. Souza","raw_affiliation_strings":["Embrapa Pecuaria Sul; BR 153 Km 604 Caixa Postal 242 CEP 96400-970 Bage Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Embrapa Pecuaria Sul; BR 153 Km 604 Caixa Postal 242 CEP 96400-970 Bage Brazil","institution_ids":["https://openalex.org/I4405285346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039781020","display_name":"Alan S. McNeilly","orcid":"https://orcid.org/0000-0002-0086-4568","observed_orcids":["https://orcid.org/0000-0002-0086-4568"]},"institutions":[{"id":"https://openalex.org/I4210116174","display_name":"MRC Centre for Reproductive Health","ror":"https://ror.org/02f4tsf92","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210116174","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. S. McNeilly","raw_affiliation_strings":["MRC Centre for Reproductive Health University of Edinburgh 47 Little France Crescent EH16 4TJ Edinburgh UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Centre for Reproductive Health University of Edinburgh 47 Little France Crescent EH16 4TJ Edinburgh UK","institution_ids":["https://openalex.org/I4210116174","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068770995","display_name":"Magda Vieira Benavides","orcid":"https://orcid.org/0000-0002-0219-3163","observed_orcids":["https://orcid.org/0000-0002-0219-3163"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. V. Benavides","raw_affiliation_strings":["Embrapa LabEx USA 5601 Sunnyside Avenue 20705\u20105141 Beltsville MD USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Embrapa LabEx USA 5601 Sunnyside Avenue 20705\u20105141 Beltsville MD USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033167034","display_name":"Eduardo O. Melo","orcid":"https://orcid.org/0000-0003-0797-920X","observed_orcids":["https://orcid.org/0000-0003-0797-920X"]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405284811","display_name":"Embrapa Recursos Gen\u00e9ticos e Biotecnologia","ror":"https://ror.org/047y8rp84","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405284811"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"E. O. Melo","raw_affiliation_strings":["Embrapa Recursos Geneticos e Biotecnologia PqEB \u2010 Av. W5 Norte (final) CEP 70770\u2010917 Brasilia Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Embrapa Recursos Geneticos e Biotecnologia PqEB \u2010 Av. W5 Norte (final) CEP 70770\u2010917 Brasilia Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284811"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075997571","display_name":"Jos\u00e9 Carlos Ferrugem Moraes","orcid":"https://orcid.org/0000-0002-1230-9000","observed_orcids":["https://orcid.org/0000-0002-1230-9000"]},"institutions":[{"id":"https://openalex.org/I4405285346","display_name":"Embrapa Pecu\u00e1ria Sul","ror":"https://ror.org/058j9ky09","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"J. C. F. Moraes","raw_affiliation_strings":["Embrapa Pecuaria Sul BR 153 Km 604 Caixa Postal 242 CEP 96400\u2010970 Bage Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Embrapa Pecuaria Sul BR 153 Km 604 Caixa Postal 242 CEP 96400\u2010970 Bage Brazil","institution_ids":["https://openalex.org/I4405285346"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5080405012"],"corresponding_institution_ids":["https://openalex.org/I4405285346"],"apc_list":{"value":3570,"currency":"USD","value_usd":3570},"apc_paid":null,"fwci":1.9257,"has_fulltext":true,"cited_by_count":67,"citation_normalized_percentile":{"value":0.85250793,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"45","issue":"5","first_page":"732","last_page":"739"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.039900001138448715,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gdf9","display_name":"GDF9","score":0.9039999842643738},{"id":"https://openalex.org/keywords/growth-differentiation-factor-9","display_name":"growth differentiation factor 9","score":0.9810000061988831},{"id":"https://openalex.org/keywords/ovulation-rate","display_name":"ovulation rate","score":0.8069999814033508},{"id":"https://openalex.org/keywords/litter-size","display_name":"litter size","score":1.0},{"id":"https://openalex.org/keywords/prolificacy","display_name":"prolificacy","score":0.8769999742507935},{"id":"https://openalex.org/keywords/sheep","display_name":"sheep","score":0.48100000619888306},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.7139999866485596},{"id":"https://openalex.org/keywords/uterine-hypoplasia","display_name":"uterine hypoplasia","score":0.7760000228881836},{"id":"https://openalex.org/keywords/ovarian-hypoplasia","display_name":"ovarian hypoplasia","score":0.9940000176429749},{"id":"https://openalex.org/keywords/oocyte-morphology","display_name":"oocyte morphology","score":0.5289999842643738},{"id":"https://openalex.org/keywords/granulosa-cells","display_name":"granulosa cells","score":0.8619999885559082},{"id":"https://openalex.org/keywords/follicular-development","display_name":"folliculogenesis","score":0.527999997138977},{"id":"https://openalex.org/keywords/infertility","display_name":"infertility","score":0.4970000088214874},{"id":"https://openalex.org/keywords/reproductive-tract-morphology","display_name":"reproductive tract morphology","score":0.5929999947547913}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8953542113304138},{"id":"https://openalex.org/C2777702977","wikidata":"https://www.wikidata.org/wiki/Q187082","display_name":"Ovulation","level":3,"score":0.8064249753952026},{"id":"https://openalex.org/C134215735","wikidata":"https://www.wikidata.org/wiki/Q120997","display_name":"Flock","level":2,"score":0.6855227947235107},{"id":"https://openalex.org/C2779429622","wikidata":"https://www.wikidata.org/wiki/Q1780867","display_name":"Litter","level":2,"score":0.532461941242218},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5063062906265259},{"id":"https://openalex.org/C2776482104","wikidata":"https://www.wikidata.org/wiki/Q38829","display_name":"Breed","level":2,"score":0.4660407602787018},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42924854159355164},{"id":"https://openalex.org/C153471976","wikidata":"https://www.wikidata.org/wiki/Q2873354","display_name":"Heterozygote advantage","level":4,"score":0.4195792078971863},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41802114248275757},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4036947190761566},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3913555145263672},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.3580590486526489},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22370150685310364},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.15078133344650269},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.08879789710044861},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001947","descriptor_name":"Breeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D006579","descriptor_name":"Heterozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006720","descriptor_name":"Homozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007246","descriptor_name":"Infertility","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008098","descriptor_name":"Litter Size","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010060","descriptor_name":"Ovulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055429","descriptor_name":"Growth Differentiation Factor 9","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055430","descriptor_name":"Bone Morphogenetic Protein 15","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1111/age.12190","doi":"https://doi.org/10.1111/age.12190","is_oa":true,"landing_page_url":"https://doi.org/10.1111/age.12190","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/age.12190","source":{"id":"https://openalex.org/S12146737","display_name":"Animal Genetics","issn_l":"0268-9146","issn":["0268-9146","1365-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Genetics","raw_type":"journal-article"},{"id":"pmid:25039891","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25039891","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal genetics","raw_type":"Journal Article"},{"id":"pmh:oai:www.alice.cnptia.embrapa.br:doc/998487","doi":null,"is_oa":true,"landing_page_url":"http://www.alice.cnptia.embrapa.br/alice/handle/doc/998487","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:EMBRAPA","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:americanae.aecid.es:2104383","doi":null,"is_oa":true,"landing_page_url":"http://www.alice.cnptia.embrapa.br/handle/doc/990530","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da EMBRAPA","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:americanae.aecid.es:2111157","doi":null,"is_oa":true,"landing_page_url":"http://www.alice.cnptia.embrapa.br/alice/handle/doc/998487","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da EMBRAPA","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:www.alice.cnptia.embrapa.br:doc/990530","doi":null,"is_oa":true,"landing_page_url":"http://www.alice.cnptia.embrapa.br/alice/handle/doc/990530","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:EMBRAPA","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1111/age.12190","doi":"https://doi.org/10.1111/age.12190","is_oa":true,"landing_page_url":"https://doi.org/10.1111/age.12190","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/age.12190","source":{"id":"https://openalex.org/S12146737","display_name":"Animal Genetics","issn_l":"0268-9146","issn":["0268-9146","1365-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Genetics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.4359000027179718,"display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2366404993","display_name":null,"funder_award_id":"0064/09-2","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G3843167401","display_name":null,"funder_award_id":"473297/2007-8","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"}],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2068625834.pdf","grobid_xml":"https://content.openalex.org/works/W2068625834.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1501791679","https://openalex.org/W1528950960","https://openalex.org/W1850732758","https://openalex.org/W1968945784","https://openalex.org/W1990518284","https://openalex.org/W1992973024","https://openalex.org/W2000559685","https://openalex.org/W2005350690","https://openalex.org/W2028523909","https://openalex.org/W2029142033","https://openalex.org/W2033371591","https://openalex.org/W2043455328","https://openalex.org/W2048546103","https://openalex.org/W2050041631","https://openalex.org/W2050954429","https://openalex.org/W2056248345","https://openalex.org/W2069549606","https://openalex.org/W2071276244","https://openalex.org/W2074773444","https://openalex.org/W2089335658","https://openalex.org/W2090660658","https://openalex.org/W2098519379","https://openalex.org/W2118094114","https://openalex.org/W2129012279","https://openalex.org/W2131311271","https://openalex.org/W2139624389","https://openalex.org/W2152519220","https://openalex.org/W2153366706","https://openalex.org/W2165267002","https://openalex.org/W2242565272"],"related_works":["https://openalex.org/W2152519220","https://openalex.org/W2153366706","https://openalex.org/W3147114161","https://openalex.org/W4389606400","https://openalex.org/W3009561888","https://openalex.org/W2071276244","https://openalex.org/W2102611028","https://openalex.org/W7133373391","https://openalex.org/W7111394845","https://openalex.org/W2908060369"],"abstract_inverted_index":{"Litter":[0],"size":[1],"(LS)":[2],"in":[3,17,27,30,68,75,99,124,135,154,164,170,211,221],"sheep":[4,156],"is":[5,226],"determined":[6],"mainly":[7],"by":[8,132],"ovulation":[9],"rate":[10],"(OR).":[11],"Several":[12],"polymorphisms":[13],"have":[14],"been":[15],"identified":[16,49],"the":[18,37,40,76,80,100,136,150,206,209,214,222,245,248,254],"growth":[19],"differentiation":[20],"factor":[21],"9":[22],"(GDF9)":[23],"gene":[24],"that":[25,219,251],"result":[26],"an":[28],"increase":[29],"OR":[31,98,110,128],"and":[32,105,138,166,181,199,234,244],"prolificacy":[33,233],"of":[34,39,51,59,79,92,174,202,208,247],"sheep.":[35],"Screening":[36],"databank":[38],"Brazilian":[41],"Sheep":[42],"Breeders":[43],"Association":[44],"for":[45,97,231],"triplet":[46],"delivery,":[47],"we":[48],"flocks":[50,146],"prolific":[52],"Ile":[53],"de":[54],"France":[55],"ewes.":[56,126,172],"After":[57,205],"resequencing":[58],"GDF9,":[60],"a":[61,69,237],"point":[62],"mutation":[63],"(c.943C>T)":[64],"was":[65,85,95,129,152],"identified,":[66],"resulting":[67],"non-conservative":[70],"amino":[71],"acid":[72],"change":[73],"(p.Arg315Cys)":[74],"cleavage":[77],"site":[78],"propeptide.":[81],"This":[82,224],"new":[83],"allele":[84],"called":[86],"Vacaria":[87,106],"(FecG(v)":[88],").":[89],"A":[90],"flock":[91],"half-sib":[93],"ewes":[94],"evaluated":[96],"first":[101],"three":[102],"breeding":[103,140],"seasons,":[104],"heterozygotes":[107,165],"had":[108],"higher":[109,153],"(P":[111,142,157],"<":[112,143,158],"0.001),":[113,159],"averaging":[114,160],"2.1":[115],"\u00b1":[116,122,162,168],"0.1":[117,123],"when":[118],"compared":[119],"to":[120,187,190,228,239],"1.2":[121],"wild-type":[125,171],"The":[127],"also":[130,235],"influenced":[131],"age,":[133],"increasing":[134],"second":[137],"third":[139],"seasons":[141],"0.001).":[144],"In":[145],"segregating":[147],"this":[148],"allele,":[149],"LS":[151],"mutant":[155],"1.61":[161],"0.07":[163],"1.29":[167],"0.03":[169],"Analysis":[173],"homozygote":[175],"reproductive":[176],"tract":[177],"morphology":[178,198],"revealed":[179],"uterine":[180],"ovarian":[182],"hypoplasia.":[183],"Ovarian":[184],"follicles":[185],"continue":[186],"develop":[188],"up":[189],"small":[191],"antral":[192],"stages,":[193],"although":[194],"with":[195],"abnormal":[196],"oocyte":[197,210,255],"altered":[200],"arrangement":[201],"granulosa":[203],"cells.":[204],"collapse":[207],"most":[212],"follicles,":[213],"remaining":[215],"cells":[216,250],"formed":[217],"clusters":[218],"persisted":[220],"ovary.":[223],"SNP":[225],"useful":[227],"improve":[229],"selection":[230],"dam":[232],"as":[236],"model":[238],"investigate":[240],"GDF9":[241],"post-translation":[242],"processing":[243],"fate":[246],"follicular":[249],"remain":[252],"after":[253],"demise.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}