{"id":"https://openalex.org/W2067845342","doi":"https://doi.org/10.1016/j.bbagen.2007.08.015","title":"Structure and function of glycosphingolipids and sphingolipids: Recollections and future trends","display_name":"Structure and function of glycosphingolipids and sphingolipids: Recollections and future trends","publication_year":2007,"publication_date":"2007-09-07","ids":{"openalex":"https://openalex.org/W2067845342","doi":"https://doi.org/10.1016/j.bbagen.2007.08.015","mag":"2067845342","pmid":"https://pubmed.ncbi.nlm.nih.gov/17976918","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2312460"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbagen.2007.08.015","doi":"https://doi.org/10.1016/j.bbagen.2007.08.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2007.08.015","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2312460","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070398233","display_name":"Sen\u2010itiroh Hakomori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sen-itiroh Hakomori","raw_affiliation_strings":["Division of Biomembrane Research, Pacific Northwest Research Institute, Seattle, WA 98122, USA. hakomori@u.washington.edu","Departments of Microbiology and Pathobiology, University of Washington, Seattle, WA 98195, USA","Division of Biomembrane Research, Pacific Northwest Research Institute, Seattle, WA 98122, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biomembrane Research, Pacific Northwest Research Institute, Seattle, WA 98122, USA. hakomori@u.washington.edu","institution_ids":[]},{"raw_affiliation_string":"Departments of Microbiology and Pathobiology, University of Washington, Seattle, WA 98195, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Division of Biomembrane Research, Pacific Northwest Research Institute, Seattle, WA 98122, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070398233"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":3310,"currency":"USD","value_usd":3310},"apc_paid":null,"fwci":1.1329,"has_fulltext":false,"cited_by_count":273,"citation_normalized_percentile":{"value":0.74871451,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"1780","issue":"3","first_page":"325","last_page":"346"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.4916999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.4916999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.47530001401901245,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycosphingolipids","display_name":"glycosphingolipids","score":1.0},{"id":"https://openalex.org/keywords/sphingolipids","display_name":"sphingolipids","score":0.9959999918937683},{"id":"https://openalex.org/keywords/tumor-associated-antigens","display_name":"tumor-associated antigens","score":0.9169999957084656},{"id":"https://openalex.org/keywords/tetraspanins","display_name":"tetraspanins","score":0.8700000047683716},{"id":"https://openalex.org/keywords/growth-factor-receptors","display_name":"growth factor receptors","score":0.9259999990463257},{"id":"https://openalex.org/keywords/integrins","display_name":"integrins","score":1.0},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.9399999976158142},{"id":"https://openalex.org/keywords/lipid-rafts","display_name":"lipid rafts","score":0.9229999780654907},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.9890000224113464},{"id":"https://openalex.org/keywords/stem-cell-biology","display_name":"stem cell biology","score":0.9679999947547913},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":1.0}],"concepts":[{"id":"https://openalex.org/C134088382","wikidata":"https://www.wikidata.org/wiki/Q6556364","display_name":"Lipid microdomain","level":3,"score":0.6815084218978882},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.6448303461074829},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5967943668365479},{"id":"https://openalex.org/C61705674","wikidata":"https://www.wikidata.org/wiki/Q410395","display_name":"Sphingolipid","level":2,"score":0.5549488663673401},{"id":"https://openalex.org/C22222904","wikidata":"https://www.wikidata.org/wiki/Q422882","display_name":"Glycolipid","level":2,"score":0.531846284866333},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.516962468624115},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5074865221977234},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.49491018056869507},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4524277150630951},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4446333050727844},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.37695345282554626},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.3675198554992676},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.2804747223854065},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2787431478500366},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.16445431113243103}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006028","descriptor_name":"Glycosphingolipids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006028","descriptor_name":"Glycosphingolipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021962","descriptor_name":"Membrane Microdomains","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbagen.2007.08.015","doi":"https://doi.org/10.1016/j.bbagen.2007.08.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2007.08.015","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},{"id":"pmid:17976918","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17976918","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2312460","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2312460","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochim Biophys Acta","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2312460","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2312460","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochim Biophys Acta","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G401348875","display_name":"GLYCOLIPIDS--CELL INTERACTION/PROLIFERATION/ONCOGENESIS","funder_award_id":"R35CA042505","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":230,"referenced_works":["https://openalex.org/W24722359","https://openalex.org/W120861911","https://openalex.org/W132171959","https://openalex.org/W138803822","https://openalex.org/W139202454","https://openalex.org/W187359374","https://openalex.org/W339216852","https://openalex.org/W576957517","https://openalex.org/W625356875","https://openalex.org/W887571285","https://openalex.org/W966237121","https://openalex.org/W1445418231","https://openalex.org/W1484817325","https://openalex.org/W1488620239","https://openalex.org/W1489982644","https://openalex.org/W1491212204","https://openalex.org/W1495309686","https://openalex.org/W1497458321","https://openalex.org/W1498685946","https://openalex.org/W1501761217","https://openalex.org/W1505156979","https://openalex.org/W1508039723","https://openalex.org/W1509074378","https://openalex.org/W1511331055","https://openalex.org/W1518310590","https://openalex.org/W1520466764","https://openalex.org/W1522379684","https://openalex.org/W1524333424","https://openalex.org/W1525426202","https://openalex.org/W1527640586","https://openalex.org/W1533329497","https://openalex.org/W1533803295","https://openalex.org/W1535201878","https://openalex.org/W1537880401","https://openalex.org/W1545910845","https://openalex.org/W1548966243","https://openalex.org/W1549953248","https://openalex.org/W1552034438","https://openalex.org/W1558191412","https://openalex.org/W1564650229","https://openalex.org/W1565148344","https://openalex.org/W1569852946","https://openalex.org/W1571455279","https://openalex.org/W1573129762","https://openalex.org/W1574227588","https://openalex.org/W1577788031","https://openalex.org/W1578547237","https://openalex.org/W1578800727","https://openalex.org/W1580721471","https://openalex.org/W1582104428","https://openalex.org/W1584475999","https://openalex.org/W1590795932","https://openalex.org/W1593582113","https://openalex.org/W1595133660","https://openalex.org/W1599917554","https://openalex.org/W1608212624","https://openalex.org/W1636416079","https://openalex.org/W1754937767","https://openalex.org/W1785702586","https://openalex.org/W1812485821","https://openalex.org/W1821376019","https://openalex.org/W1939504737","https://openalex.org/W1954229558","https://openalex.org/W1960275605","https://openalex.org/W1963631969","https://openalex.org/W1968787781","https://openalex.org/W1968807484","https://openalex.org/W1970230999","https://openalex.org/W1971099739","https://openalex.org/W1971664603","https://openalex.org/W1971731473","https://openalex.org/W1971749962","https://openalex.org/W1972049323","https://openalex.org/W1973228170","https://openalex.org/W1973618659","https://openalex.org/W1974299852","https://openalex.org/W1974506413","https://openalex.org/W1978637038","https://openalex.org/W1978688558","https://openalex.org/W1981025721","https://openalex.org/W1981752846","https://openalex.org/W1982413953","https://openalex.org/W1982731253","https://openalex.org/W1985760249","https://openalex.org/W1986470941","https://openalex.org/W1987227850","https://openalex.org/W1987759495","https://openalex.org/W1987835768","https://openalex.org/W1990632594","https://openalex.org/W1990670652","https://openalex.org/W1991155810","https://openalex.org/W1993939182","https://openalex.org/W1994360114","https://openalex.org/W1994570495","https://openalex.org/W1996382554","https://openalex.org/W1998475310","https://openalex.org/W1998760926","https://openalex.org/W1999595098","https://openalex.org/W2000973050","https://openalex.org/W2001743581","https://openalex.org/W2002531098","https://openalex.org/W2003788286","https://openalex.org/W2004813532","https://openalex.org/W2004999534","https://openalex.org/W2005244540","https://openalex.org/W2005343690","https://openalex.org/W2005544166","https://openalex.org/W2005723964","https://openalex.org/W2006323812","https://openalex.org/W2008161863","https://openalex.org/W2008367326","https://openalex.org/W2011027448","https://openalex.org/W2011189175","https://openalex.org/W2013181324","https://openalex.org/W2013381560","https://openalex.org/W2016566860","https://openalex.org/W2017767253","https://openalex.org/W2018410272","https://openalex.org/W2018511244","https://openalex.org/W2021570486","https://openalex.org/W2026005196","https://openalex.org/W2026158123","https://openalex.org/W2027429767","https://openalex.org/W2028490608","https://openalex.org/W2028601165","https://openalex.org/W2029231027","https://openalex.org/W2029555501","https://openalex.org/W2031034856","https://openalex.org/W2031775276","https://openalex.org/W2032002692","https://openalex.org/W2032359283","https://openalex.org/W2036044676","https://openalex.org/W2037997375","https://openalex.org/W2040527066","https://openalex.org/W2040895383","https://openalex.org/W2042619166","https://openalex.org/W2043635596","https://openalex.org/W2043762044","https://openalex.org/W2043945964","https://openalex.org/W2044846660","https://openalex.org/W2046353286","https://openalex.org/W2046788126","https://openalex.org/W2046802065","https://openalex.org/W2047275732","https://openalex.org/W2047867213","https://openalex.org/W2049117098","https://openalex.org/W2049583947","https://openalex.org/W2049727415","https://openalex.org/W2051159732","https://openalex.org/W2056525230","https://openalex.org/W2057025013","https://openalex.org/W2059815227","https://openalex.org/W2061533577","https://openalex.org/W2062559835","https://openalex.org/W2062809449","https://openalex.org/W2068073042","https://openalex.org/W2071292533","https://openalex.org/W2075283047","https://openalex.org/W2077462602","https://openalex.org/W2081541275","https://openalex.org/W2082097992","https://openalex.org/W2082399753","https://openalex.org/W2083983934","https://openalex.org/W2086674389","https://openalex.org/W2093847817","https://openalex.org/W2094238788","https://openalex.org/W2095138871","https://openalex.org/W2096012158","https://openalex.org/W2096240985","https://openalex.org/W2098862614","https://openalex.org/W2101730120","https://openalex.org/W2102525592","https://openalex.org/W2103062633","https://openalex.org/W2105225386","https://openalex.org/W2105700771","https://openalex.org/W2113069743","https://openalex.org/W2113406360","https://openalex.org/W2116850184","https://openalex.org/W2121493672","https://openalex.org/W2121936687","https://openalex.org/W2122286836","https://openalex.org/W2126029855","https://openalex.org/W2129968911","https://openalex.org/W2136390065","https://openalex.org/W2137377563","https://openalex.org/W2138101780","https://openalex.org/W2138728266","https://openalex.org/W2146421447","https://openalex.org/W2147618382","https://openalex.org/W2150975192","https://openalex.org/W2154000442","https://openalex.org/W2157834399","https://openalex.org/W2158343596","https://openalex.org/W2158361441","https://openalex.org/W2162399997","https://openalex.org/W2162566855","https://openalex.org/W2164505756","https://openalex.org/W2165022280","https://openalex.org/W2167284102","https://openalex.org/W2177077947","https://openalex.org/W2185468204","https://openalex.org/W2312476167","https://openalex.org/W2314590516","https://openalex.org/W2315806216","https://openalex.org/W2315974477","https://openalex.org/W2317577047","https://openalex.org/W2322701898","https://openalex.org/W2331340688","https://openalex.org/W2395289450","https://openalex.org/W2403448201","https://openalex.org/W2403991754","https://openalex.org/W2410741308","https://openalex.org/W2415457676","https://openalex.org/W2418758732","https://openalex.org/W2418773083","https://openalex.org/W2472617568","https://openalex.org/W2576742884","https://openalex.org/W2587827722","https://openalex.org/W4232671899","https://openalex.org/W4235428970","https://openalex.org/W4237880270","https://openalex.org/W4248474603","https://openalex.org/W4249982117","https://openalex.org/W6605616459","https://openalex.org/W6632359623","https://openalex.org/W6634870409","https://openalex.org/W6664863411","https://openalex.org/W6676030295","https://openalex.org/W6678398518","https://openalex.org/W6682727062"],"related_works":["https://openalex.org/W2020994320","https://openalex.org/W2312798744","https://openalex.org/W2166371391","https://openalex.org/W3119733985","https://openalex.org/W2562556696","https://openalex.org/W1222044264","https://openalex.org/W2035242228","https://openalex.org/W2091399531","https://openalex.org/W2064107742","https://openalex.org/W187359374"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":23},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":20},{"year":2013,"cited_by_count":22},{"year":2012,"cited_by_count":22}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
