{"id":"https://openalex.org/W2067796356","doi":"https://doi.org/10.1016/j.bpj.2008.12.093","title":"Probing Structure and Mechanics of Yeast Prion Proteins with Optical Tweezers","display_name":"Probing Structure and Mechanics of Yeast Prion Proteins with Optical Tweezers","publication_year":2009,"publication_date":"2009-02-01","ids":{"openalex":"https://openalex.org/W2067796356","doi":"https://doi.org/10.1016/j.bpj.2008.12.093","mag":"2067796356"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2008.12.093","doi":"https://doi.org/10.1016/j.bpj.2008.12.093","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2008.12.093","pdf_url":"http://www.cell.com/article/S0006349508002191/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349508002191/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090710614","display_name":"Carlos Ernesto Castro","orcid":"https://orcid.org/0000-0001-7023-6105","observed_orcids":["https://orcid.org/0000-0001-7023-6105"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlos E. Castro","raw_affiliation_strings":["MIT, Cambridge, MA, USA","MIT, Cambridge MA, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MIT, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"MIT, Cambridge MA, USA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022552570","display_name":"Jijun Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jijun Dong","raw_affiliation_strings":["MIT, Cambridge, MA, USA","MIT, Cambridge MA, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MIT, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"MIT, Cambridge MA, USA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083522877","display_name":"Mary C. Boyce","orcid":"https://orcid.org/0000-0002-4908-8061","observed_orcids":["https://orcid.org/0000-0002-4908-8061"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Boyce","raw_affiliation_strings":["MIT, Cambridge, MA, USA","MIT, Cambridge MA, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MIT, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"MIT, Cambridge MA, USA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108509230","display_name":"Susan Lee Lindquist","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Lindquist","raw_affiliation_strings":["MIT, Cambridge, MA, USA","MIT, Cambridge MA, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MIT, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"MIT, Cambridge MA, USA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044940094","display_name":"Matthew J. Lang","orcid":"https://orcid.org/0000-0002-8198-144X","observed_orcids":["https://orcid.org/0000-0002-8198-144X","https://orcid.org/0000-0002-4614-251X"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matt Lang","raw_affiliation_strings":["MIT, Cambridge, MA, USA","MIT, Cambridge MA, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MIT, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"MIT, Cambridge MA, USA#TAB#","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15723995,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"96","issue":"3","first_page":"38a","last_page":"39a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":0.6176999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":0.6176999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.14309999346733093,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.10769999772310257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sup35","display_name":"Sup35","score":0.7860000133514404},{"id":"https://openalex.org/keywords/yeast-prions","display_name":"yeast prions","score":0.8190000057220459},{"id":"https://openalex.org/keywords/psi-prion","display_name":"[PSI+] prion","score":0.7990000247955322},{"id":"https://openalex.org/keywords/amyloid-fibrils","display_name":"amyloid fibrils","score":0.8640000224113464},{"id":"https://openalex.org/keywords/protein-mechanics","display_name":"protein mechanics","score":0.4819999933242798},{"id":"https://openalex.org/keywords/persistence-length","display_name":"persistence length","score":0.8479999899864197},{"id":"https://openalex.org/keywords/worm-like-chain-model","display_name":"worm-like chain model","score":0.8100000023841858}],"concepts":[{"id":"https://openalex.org/C20198109","wikidata":"https://www.wikidata.org/wiki/Q1066633","display_name":"Optical tweezers","level":2,"score":0.8649219870567322},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.6486504673957825},{"id":"https://openalex.org/C519885992","wikidata":"https://www.wikidata.org/wiki/Q161","display_name":"Fiber","level":2,"score":0.5277752876281738},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.474395751953125},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44990476965904236},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.4448012113571167},{"id":"https://openalex.org/C194232370","wikidata":"https://www.wikidata.org/wiki/Q162","display_name":"Optical fiber","level":2,"score":0.4341290593147278},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.43128079175949097},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.3785495162010193},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.35481810569763184},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.17303192615509033},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16337373852729797},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12333858013153076},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11370301246643066},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1104060709476471},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bpj.2008.12.093","doi":"https://doi.org/10.1016/j.bpj.2008.12.093","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2008.12.093","pdf_url":"http://www.cell.com/article/S0006349508002191/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2008.12.093","doi":"https://doi.org/10.1016/j.bpj.2008.12.093","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2008.12.093","pdf_url":"http://www.cell.com/article/S0006349508002191/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2067796356.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2090927113","https://openalex.org/W1521570006","https://openalex.org/W2354871061","https://openalex.org/W1549235556","https://openalex.org/W4415781480","https://openalex.org/W4255567079","https://openalex.org/W2073886687","https://openalex.org/W2479211350","https://openalex.org/W3036012635","https://openalex.org/W2053645656"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}