{"id":"https://openalex.org/W20675541","doi":null,"title":"Merkel cell carcinoma: combined surgery and radiation therapy.","display_name":"Merkel cell carcinoma: combined surgery and radiation therapy.","publication_year":1986,"publication_date":"1986-03-01","ids":{"openalex":"https://openalex.org/W20675541","mag":"20675541","pmid":"https://pubmed.ncbi.nlm.nih.gov/3954263"},"language":"en","primary_location":{"id":"pmid:3954263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3954263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American surgeon","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051559086","display_name":"Alvin M. Cotlar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A M Cotlar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054843781","display_name":"Jason Gates","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J O Gates","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110109951","display_name":"F. A. Gibbs","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F A Gibbs","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3569,"has_fulltext":false,"cited_by_count":106,"citation_normalized_percentile":{"value":0.9175972,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"52","issue":"3","first_page":"159","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11868","display_name":"Cancer and Skin Lesions","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/merkel-cell-carcinoma","display_name":"Merkel cell carcinoma","score":1.0},{"id":"https://openalex.org/keywords/combined-surgery-and-radiotherapy","display_name":"combined surgery and radiotherapy","score":0.7419999837875366},{"id":"https://openalex.org/keywords/wide-local-excision","display_name":"wide local excision","score":0.9210000038146973},{"id":"https://openalex.org/keywords/postoperative-radiotherapy","display_name":"postoperative radiotherapy","score":0.7699999809265137},{"id":"https://openalex.org/keywords/regional-lymphadenectomy","display_name":"regional lymphadenectomy","score":0.8960000276565552},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/local-recurrence","display_name":"local recurrence","score":0.8600000143051147},{"id":"https://openalex.org/keywords/radiosensitivity","display_name":"radiosensitivity","score":0.875},{"id":"https://openalex.org/keywords/skin-tumors","display_name":"skin tumors","score":0.4490000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9667021632194519},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.7838100790977478},{"id":"https://openalex.org/C2778342957","wikidata":"https://www.wikidata.org/wiki/Q1711744","display_name":"Merkel cell carcinoma","level":3,"score":0.779495120048523},{"id":"https://openalex.org/C2780824555","wikidata":"https://www.wikidata.org/wiki/Q1809305","display_name":"Lymphadenectomy","level":3,"score":0.7236025333404541},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5906556248664856},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.5683369636535645},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.5451691150665283},{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.46803951263427734},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4555879235267639},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3233523666858673},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15816712379455566}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:3954263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3954263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American surgeon","raw_type":"Case Reports"},{"id":"mag:20675541","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3954263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":96,"referenced_works":["https://openalex.org/W1523331897","https://openalex.org/W1525224329","https://openalex.org/W1528220495","https://openalex.org/W1531970760","https://openalex.org/W1541256063","https://openalex.org/W1556302024","https://openalex.org/W1578729184","https://openalex.org/W1662116282","https://openalex.org/W1780135617","https://openalex.org/W1890789143","https://openalex.org/W1906171535","https://openalex.org/W1947047050","https://openalex.org/W1964283706","https://openalex.org/W1966742803","https://openalex.org/W1972443719","https://openalex.org/W1974780945","https://openalex.org/W1975075532","https://openalex.org/W1976090430","https://openalex.org/W1978090494","https://openalex.org/W1981576632","https://openalex.org/W1983861507","https://openalex.org/W1984526892","https://openalex.org/W1987969345","https://openalex.org/W1989510040","https://openalex.org/W1990710075","https://openalex.org/W1990768518","https://openalex.org/W1992122388","https://openalex.org/W1992718978","https://openalex.org/W1995314262","https://openalex.org/W1998246707","https://openalex.org/W2005216066","https://openalex.org/W2005886235","https://openalex.org/W2006980589","https://openalex.org/W2011779329","https://openalex.org/W2014934108","https://openalex.org/W2016139728","https://openalex.org/W2017907872","https://openalex.org/W2019435702","https://openalex.org/W2027199621","https://openalex.org/W2027581951","https://openalex.org/W2030142800","https://openalex.org/W2033240573","https://openalex.org/W2033357754","https://openalex.org/W2033465619","https://openalex.org/W2034188480","https://openalex.org/W2035173545","https://openalex.org/W2037967237","https://openalex.org/W2039370814","https://openalex.org/W2040603631","https://openalex.org/W2043355876","https://openalex.org/W2046628294","https://openalex.org/W2047545717","https://openalex.org/W2055985537","https://openalex.org/W2057138322","https://openalex.org/W2058020470","https://openalex.org/W2058162461","https://openalex.org/W2058520514","https://openalex.org/W2063660893","https://openalex.org/W2063941099","https://openalex.org/W2065083920","https://openalex.org/W2066538437","https://openalex.org/W2068395093","https://openalex.org/W2070117770","https://openalex.org/W2070584691","https://openalex.org/W2071051384","https://openalex.org/W2077883552","https://openalex.org/W2077925191","https://openalex.org/W2078394646","https://openalex.org/W2078820537","https://openalex.org/W2080112453","https://openalex.org/W2081595932","https://openalex.org/W2092122589","https://openalex.org/W2096118264","https://openalex.org/W2097656996","https://openalex.org/W2098453482","https://openalex.org/W2104194825","https://openalex.org/W2106181213","https://openalex.org/W2116603854","https://openalex.org/W2116807741","https://openalex.org/W2119493536","https://openalex.org/W2120714892","https://openalex.org/W2127475487","https://openalex.org/W2133709520","https://openalex.org/W2136367673","https://openalex.org/W2139921047","https://openalex.org/W2141123131","https://openalex.org/W2151616690","https://openalex.org/W2157635376","https://openalex.org/W2157922331","https://openalex.org/W2158203357","https://openalex.org/W2169402853","https://openalex.org/W2218142692","https://openalex.org/W2271853819","https://openalex.org/W2275786821","https://openalex.org/W2408077389","https://openalex.org/W2473483591"],"related_works":["https://openalex.org/W2411523048","https://openalex.org/W2040950588","https://openalex.org/W2023803043","https://openalex.org/W2463192415","https://openalex.org/W2466571680","https://openalex.org/W2123155879","https://openalex.org/W1986413847","https://openalex.org/W1997676349","https://openalex.org/W2401958248","https://openalex.org/W1995913070"],"abstract_inverted_index":{"Merkel":[0,198],"cell":[1,199],"carcinoma,":[2],"first":[3,72],"reported":[4,82],"as":[5],"\"trabecular":[6],"carcinoma\"":[7],"by":[8],"Toker":[9],"in":[10,49,83,89,97,105,113,129,159,197],"1972,":[11],"is":[12,30,154,164,169],"a":[13,34,61],"dangerous,":[14],"often":[15],"fatal":[16],"primary":[17],"skin":[18],"tumor.":[19],"The":[20,123],"current":[21],"authors":[22],"report":[23],"eight":[24],"patients,":[25],"only":[26,130],"one":[27,43,131],"of":[28,68,79,108,157,195],"whom":[29],"considered":[31],"to":[32,51,147,179],"have":[33],"totally":[35],"successful":[36],"clinical":[37],"outcome.":[38],"Two":[39,54],"patients":[40,65,81,112],"died":[41,66],"and":[42,63,101,128,151,176,192],"was":[44,125,133],"preterminal":[45],"with":[46,120,143],"widespread":[47],"disease":[48,70],"10":[50],"20":[52],"months.":[53],"others":[55],"had":[56],"recurrence":[57,88,135],"or":[58],"metastases":[59,96],"within":[60,136],"year,":[62],"two":[64],"early":[67,160,191],"intercurrent":[69],"after":[71],"developing":[73],"regional":[74,93,152],"lymph":[75,94],"node":[76,95],"involvement.":[77],"Review":[78],"139":[80],"the":[84,109,114,148,155,203],"literature":[85],"indicates":[86],"local":[87,149],"30":[90],"per":[91,99,107],"cent,":[92,100],"50":[98],"death":[102],"from":[103],"neoplasm":[104,182],"18":[106],"cases.":[110],"All":[111],"present":[115],"series":[116],"received":[117],"radiation":[118],"therapy":[119,156],"encouraging":[121],"response.":[122],"tumor":[124],"quite":[126],"radiosensitive,":[127],"instance":[132],"there":[134],"an":[137,172],"irradiated":[138],"field.":[139],"Wide":[140],"surgical":[141,175],"excision":[142],"prompt":[144],"postoperative":[145],"irradiation":[146],"site":[150],"lymphatics":[153],"choice":[158],"lesions.":[161],"Regional":[162],"lymphadenectomy":[163],"recommended":[165],"whenever":[166],"nodal":[167],"involvement":[168],"suspected.":[170],"Currently,":[171],"aggressive":[173],"combined":[174],"radio-therapeutic":[177],"approach":[178],"this":[180],"dangerous":[181],"appears":[183],"warranted,":[184],"although":[185],"further":[186],"data":[187],"may":[188],"show":[189],"that":[190],"routine":[193],"use":[194],"radiotherapy":[196],"carcinoma":[200],"could":[201],"obviate":[202],"necessity":[204],"for":[205],"extensive":[206],"operative":[207],"procedures.":[208]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}