{"id":"https://openalex.org/W2067513239","doi":"https://doi.org/10.1016/0024-3205(93)90156-w","title":"Endothelial potentiation of relaxation response to ascorbic acid in rat and guinea pog thoracic aorta","display_name":"Endothelial potentiation of relaxation response to ascorbic acid in rat and guinea pog thoracic aorta","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2067513239","doi":"https://doi.org/10.1016/0024-3205(93)90156-w","mag":"2067513239","pmid":"https://pubmed.ncbi.nlm.nih.gov/8421431"},"language":"en","primary_location":{"id":"doi:10.1016/0024-3205(93)90156-w","doi":"https://doi.org/10.1016/0024-3205(93)90156-w","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0024-3205(93)90156-w","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011798225","display_name":"Ki Churl Chang","orcid":"https://orcid.org/0000-0001-6420-6428","observed_orcids":["https://orcid.org/0000-0001-6420-6428"]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ki Churl Chang","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju, Korea","Cardiovascular Research Institute, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju, Korea","institution_ids":["https://openalex.org/I189442560"]},{"raw_affiliation_string":"Cardiovascular Research Institute, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]},{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054021469","display_name":"Won Seog Chong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Won Seog Chong","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111520644","display_name":"Dong\u2010Ryul Sohn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dong-Ryul Sohn","raw_affiliation_strings":["Cardiovascular Research Institute, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]},{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033764464","display_name":"Bok Hee Kwon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Bok Hee Kwon","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103435014","display_name":"In Jae Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"In Jae Lee","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091033501","display_name":"Chi Yeon Kim","orcid":"https://orcid.org/0000-0002-1688-2189","observed_orcids":["https://orcid.org/0000-0002-1688-2189"]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chi Yeon Kim","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102143018","display_name":"Jeong Soo Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jeong Soo Yang","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]},{"author_position":"last","author":{"id":null,"display_name":"Jung Il Joo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189442560","display_name":"Gyeongsang National University","ror":"https://ror.org/00saywf64","country_code":"KR","type":"education","lineage":["https://openalex.org/I189442560"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jung Il Joo","raw_affiliation_strings":["Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Medicine, Gyeongsang National University, Chinju 660-280, Korea","institution_ids":["https://openalex.org/I189442560"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I189442560"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":0.3971,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.60834763,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"52","issue":"4","first_page":"PL37","last_page":"PL42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.01080000028014183,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9679999947547913},{"id":"https://openalex.org/keywords/endothelium","display_name":"endothelium","score":0.7689999938011169},{"id":"https://openalex.org/keywords/vasorelaxation","display_name":"vasorelaxation","score":0.7730000019073486},{"id":"https://openalex.org/keywords/thoracic-aorta","display_name":"thoracic aorta","score":0.9190000295639038},{"id":"https://openalex.org/keywords/methylene-blue","display_name":"methylene blue","score":0.8560000061988831},{"id":"https://openalex.org/keywords/calcium-channels","display_name":"calcium channels","score":0.7580000162124634},{"id":"https://openalex.org/keywords/phenylephrine-induced-contraction","display_name":"phenylephrine-induced contraction","score":0.7409999966621399},{"id":"https://openalex.org/keywords/potassium-chloride-depolarization","display_name":"potassium chloride depolarization","score":0.675000011920929},{"id":"https://openalex.org/keywords/acetylcholine","display_name":"acetylcholine","score":0.847000002861023},{"id":"https://openalex.org/keywords/a23187","display_name":"A23187","score":0.9259999990463257},{"id":"https://openalex.org/keywords/endothelium-dependent-relaxation","display_name":"endothelium-dependent relaxation","score":0.7419999837875366},{"id":"https://openalex.org/keywords/calcium-induced-contraction","display_name":"calcium-induced contraction","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.9523664712905884},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.627002477645874},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.6210582256317139},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6104117035865784},{"id":"https://openalex.org/C2779191827","wikidata":"https://www.wikidata.org/wiki/Q422134","display_name":"Methylene blue","level":4,"score":0.6017375588417053},{"id":"https://openalex.org/C2777952589","wikidata":"https://www.wikidata.org/wiki/Q421910","display_name":"Phenylephrine","level":3,"score":0.5738080739974976},{"id":"https://openalex.org/C2776864027","wikidata":"https://www.wikidata.org/wiki/Q615993","display_name":"Thoracic aorta","level":3,"score":0.5344129800796509},{"id":"https://openalex.org/C2778815084","wikidata":"https://www.wikidata.org/wiki/Q79803","display_name":"Guinea pig","level":2,"score":0.5209925770759583},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.49238479137420654},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.45536890625953674},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4369063973426819},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39189380407333374},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.34037190675735474},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.32175901532173157},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2021503448486328},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1914696991443634},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.048098593950271606},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C65165184","wikidata":"https://www.wikidata.org/wiki/Q218831","display_name":"Photocatalysis","level":3,"score":0.0},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0024-3205(93)90156-w","doi":"https://doi.org/10.1016/0024-3205(93)90156-w","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0024-3205(93)90156-w","pdf_url":null,"source":{"id":"https://openalex.org/S175775512","display_name":"Life Sciences","issn_l":"0024-3205","issn":["0024-3205","1879-0631"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life Sciences","raw_type":"journal-article"},{"id":"pmid:8421431","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8421431","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W177436899","https://openalex.org/W1930241290","https://openalex.org/W1944862464","https://openalex.org/W1987165240","https://openalex.org/W1992718978","https://openalex.org/W1994090310","https://openalex.org/W1994614876","https://openalex.org/W2015996189","https://openalex.org/W2028079895","https://openalex.org/W2033812096","https://openalex.org/W2036861767","https://openalex.org/W2038851254","https://openalex.org/W2043474405","https://openalex.org/W2068742980","https://openalex.org/W2129367506","https://openalex.org/W2169182236","https://openalex.org/W2418387999"],"related_works":["https://openalex.org/W2044064751","https://openalex.org/W4327666956","https://openalex.org/W2162554582","https://openalex.org/W2264804057","https://openalex.org/W2005115308","https://openalex.org/W7098042249","https://openalex.org/W2018697808","https://openalex.org/W2465811122","https://openalex.org/W2076025395","https://openalex.org/W7202395127"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}