{"id":"https://openalex.org/W2067503166","doi":"https://doi.org/10.1016/0009-8981(81)90449-6","title":"A stable isotope dilution assay for the antiparkinsonian drug benztropine in biological fluids","display_name":"A stable isotope dilution assay for the antiparkinsonian drug benztropine in biological fluids","publication_year":1981,"publication_date":"1981-05-01","ids":{"openalex":"https://openalex.org/W2067503166","doi":"https://doi.org/10.1016/0009-8981(81)90449-6","mag":"2067503166","pmid":"https://pubmed.ncbi.nlm.nih.gov/7016378"},"language":"en","primary_location":{"id":"doi:10.1016/0009-8981(81)90449-6","doi":"https://doi.org/10.1016/0009-8981(81)90449-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0009-8981(81)90449-6","pdf_url":null,"source":{"id":"https://openalex.org/S207549998","display_name":"Clinica Chimica Acta","issn_l":"0009-8981","issn":["0009-8981","1873-3492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica Chimica Acta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014516948","display_name":"Satya P. Jindal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satya P. Jindal","raw_affiliation_strings":["Rockland Research Institute, Orangeburg, New York 10962 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rockland Research Institute, Orangeburg, New York 10962 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Theresa Lutz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Theresa Lutz","raw_affiliation_strings":["Rockland Research Institute, Orangeburg, New York 10962 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rockland Research Institute, Orangeburg, New York 10962 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045182016","display_name":"Cosmo Hallstr\u00f6m","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cosmo Hallstrom","raw_affiliation_strings":["Rockland Research Institute, Orangeburg, New York 10962 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rockland Research Institute, Orangeburg, New York 10962 U.S.A","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110159022","display_name":"Per Vestergaard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Per Vestergaard","raw_affiliation_strings":["Rockland Research Institute, Orangeburg, New York 10962 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rockland Research Institute, Orangeburg, New York 10962 U.S.A","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":1.152,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.75965217,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"112","issue":"3","first_page":"267","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.03849999979138374,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benztropine","display_name":"benztropine","score":1.0},{"id":"https://openalex.org/keywords/stable-isotope-dilution","display_name":"stable isotope dilution","score":0.8220000267028809},{"id":"https://openalex.org/keywords/antiparkinsonian-drugs","display_name":"antiparkinsonian drugs","score":0.8769999742507935},{"id":"https://openalex.org/keywords/plasma-drug-quantitation","display_name":"plasma drug quantification","score":0.6949999928474426},{"id":"https://openalex.org/keywords/urine","display_name":"urine","score":0.4390000104904175},{"id":"https://openalex.org/keywords/internal-standard","display_name":"internal standard","score":0.6190000176429749},{"id":"https://openalex.org/keywords/therapeutic-drug-monitoring","display_name":"therapeutic drug monitoring","score":0.6439999938011169},{"id":"https://openalex.org/keywords/electron-impact-ionization","display_name":"electron impact ionization","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C2910393698","wikidata":"https://www.wikidata.org/wiki/Q415026","display_name":"Benztropine","level":3,"score":0.9567899703979492},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8480687737464905},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7281172275543213},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.5409407019615173},{"id":"https://openalex.org/C123460561","wikidata":"https://www.wikidata.org/wiki/Q677065","display_name":"Gas chromatography","level":2,"score":0.43231311440467834},{"id":"https://openalex.org/C179302884","wikidata":"https://www.wikidata.org/wiki/Q7447710","display_name":"Selected ion monitoring","level":4,"score":0.414531946182251},{"id":"https://openalex.org/C171679685","wikidata":"https://www.wikidata.org/wiki/Q3707695","display_name":"Isotope dilution","level":3,"score":0.41423851251602173},{"id":"https://openalex.org/C205345274","wikidata":"https://www.wikidata.org/wiki/Q873009","display_name":"Gas chromatography\u2013mass spectrometry","level":3,"score":0.36239147186279297},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.25099217891693115},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09546524286270142},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09311851859092712},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.05478820204734802},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.05104836821556091}],"mesh":[{"descriptor_ui":"D001590","descriptor_name":"Benztropine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001590","descriptor_name":"Benztropine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001590","descriptor_name":"Benztropine","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D003903","descriptor_name":"Deuterium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007201","descriptor_name":"Indicator Dilution Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008401","descriptor_name":"Gas Chromatography-Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014326","descriptor_name":"Tropanes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0009-8981(81)90449-6","doi":"https://doi.org/10.1016/0009-8981(81)90449-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0009-8981(81)90449-6","pdf_url":null,"source":{"id":"https://openalex.org/S207549998","display_name":"Clinica Chimica Acta","issn_l":"0009-8981","issn":["0009-8981","1873-3492"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica Chimica Acta","raw_type":"journal-article"},{"id":"pmid:7016378","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7016378","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica chimica acta; international journal of clinical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W142457060","https://openalex.org/W1485685653","https://openalex.org/W2027482077","https://openalex.org/W2029519723","https://openalex.org/W2034748612","https://openalex.org/W2075667550","https://openalex.org/W2089281717","https://openalex.org/W2317238632","https://openalex.org/W2402399085","https://openalex.org/W2474551189","https://openalex.org/W3198223111","https://openalex.org/W4302316638"],"related_works":["https://openalex.org/W2141280765","https://openalex.org/W1989268401","https://openalex.org/W1984818757","https://openalex.org/W2045722945","https://openalex.org/W2107390891","https://openalex.org/W2067346366","https://openalex.org/W2045748874","https://openalex.org/W2141723472","https://openalex.org/W2146552065","https://openalex.org/W1449871073"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}