{"id":"https://openalex.org/W2067404352","doi":"https://doi.org/10.1271/bbb.58.1213","title":"Effect of Milk Whey and Its Fermentation Products by Lactic Acid Bacteria on Mitochondrial Lipid Peroxide and Hepatic Injury in Bile Duct-ligated Rats","display_name":"Effect of Milk Whey and Its Fermentation Products by Lactic Acid Bacteria on Mitochondrial Lipid Peroxide and Hepatic Injury in Bile Duct-ligated Rats","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2067404352","doi":"https://doi.org/10.1271/bbb.58.1213","mag":"2067404352"},"language":"en","primary_location":{"id":"doi:10.1271/bbb.58.1213","doi":"https://doi.org/10.1271/bbb.58.1213","is_oa":false,"landing_page_url":"https://doi.org/10.1271/bbb.58.1213","pdf_url":null,"source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086532252","display_name":"Mohsen A. Zommara","orcid":"https://orcid.org/0000-0002-1090-5570","observed_orcids":["https://orcid.org/0000-0002-1090-5570"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mohsen Zommara","raw_affiliation_strings":["Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032225484","display_name":"Hironori Takagi","orcid":"https://orcid.org/0000-0001-5438-2479","observed_orcids":["https://orcid.org/0000-0001-5438-2479"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hironori Takagi","raw_affiliation_strings":["Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110169418","display_name":"Masanobu Sakono","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanobu Sakono","raw_affiliation_strings":["Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056645736","display_name":"Yutaka Suzuki","orcid":"https://orcid.org/0000-0003-4852-1879","observed_orcids":["https://orcid.org/0000-0003-4852-1879"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]},{"id":"https://openalex.org/I4210141468","display_name":"Megmilk Snow Brand (Japan)","ror":"https://ror.org/03y46gc61","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210141468"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaka Suzuki","raw_affiliation_strings":["Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan","Technical Research Institute, Snow Brand Milk Products Co., Ltd., Kawagoe 350, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan","institution_ids":["https://openalex.org/I135598925"]},{"raw_affiliation_string":"Technical Research Institute, Snow Brand Milk Products Co., Ltd., Kawagoe 350, Japan","institution_ids":["https://openalex.org/I4210141468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111667141","display_name":"Katsumi Imaizumi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Katsumi Imaizumi","raw_affiliation_strings":["Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Nutrition Chemistry, Department of Food Science and Technology, School of Agriculture (46\u201309), Kyushu University, Fukuoka 812, Japan","institution_ids":["https://openalex.org/I135598925"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111667141"],"corresponding_institution_ids":["https://openalex.org/I135598925"],"apc_list":{"value":3272,"currency":"USD","value_usd":3272},"apc_paid":null,"fwci":0.6515,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.70202446,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"58","issue":"7","first_page":"1213","last_page":"1217"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.7851999998092651,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.7851999998092651,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.04500000178813934,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.03060000017285347,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/whey","display_name":"whey","score":0.9890000224113464},{"id":"https://openalex.org/keywords/lactic-acid-bacteria-fermentation","display_name":"lactic acid bacteria fermentation","score":0.7620000243186951},{"id":"https://openalex.org/keywords/bifidobacterium-longum","display_name":"Bifidobacterium longum","score":0.9369999766349792},{"id":"https://openalex.org/keywords/lactobacillus-acidophilus","display_name":"Lactobacillus acidophilus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bile-duct-ligation","display_name":"bile duct ligation","score":0.8989999890327454},{"id":"https://openalex.org/keywords/cholestasis","display_name":"cholestasis","score":0.8429999947547913},{"id":"https://openalex.org/keywords/lipid-hydroperoxides","display_name":"lipid hydroperoxides","score":0.7559999823570251},{"id":"https://openalex.org/keywords/liver-injury","display_name":"liver injury","score":0.7590000033378601},{"id":"https://openalex.org/keywords/vitamin-e-deficiency","display_name":"vitamin E deficiency","score":0.8619999885559082},{"id":"https://openalex.org/keywords/alpha-tocopherol","display_name":"alpha-tocopherol","score":0.9549999833106995},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.38100001215934753}],"concepts":[{"id":"https://openalex.org/C2777221637","wikidata":"https://www.wikidata.org/wiki/Q132644","display_name":"Lactobacillus acidophilus","level":4,"score":0.6258580088615417},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5396859645843506},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5217200517654419},{"id":"https://openalex.org/C2776996202","wikidata":"https://www.wikidata.org/wiki/Q4904768","display_name":"Bifidobacterium longum","level":5,"score":0.5048900246620178},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.4374512732028961},{"id":"https://openalex.org/C2778724459","wikidata":"https://www.wikidata.org/wiki/Q127900","display_name":"Lactose","level":2,"score":0.41387131810188293},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.4045499563217163},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39267659187316895},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.3450186252593994},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33200347423553467},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.28076136112213135},{"id":"https://openalex.org/C2780305828","wikidata":"https://www.wikidata.org/wiki/Q132656","display_name":"Bifidobacterium","level":4,"score":0.27359145879745483},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.203825443983078},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1271/bbb.58.1213","doi":"https://doi.org/10.1271/bbb.58.1213","is_oa":false,"landing_page_url":"https://doi.org/10.1271/bbb.58.1213","pdf_url":null,"source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W6631984995","https://openalex.org/W6670102073"],"related_works":["https://openalex.org/W2287664140","https://openalex.org/W2086148131","https://openalex.org/W2401495398","https://openalex.org/W1983325935","https://openalex.org/W2040318475","https://openalex.org/W2014989719","https://openalex.org/W2036677138","https://openalex.org/W2185281886","https://openalex.org/W2019369579","https://openalex.org/W4200231042"],"abstract_inverted_index":{"The":[0,60,130,191,217],"study":[1],"was":[2,197,227],"carried":[3],"out":[4],"to":[5,33,223],"assess":[6],"whether":[7],"bovine":[8],"milk":[9,76,80,136,161,205,208,236,253],"whey":[10,77,81,137,159,162,206,209,237,254],"and":[11,52,70,92,111,122,152,160,167,188,207,214],"its":[12],"products":[13],"fermented":[14,82,138,163,210,238,255],"by":[15,245],"lactic":[16,257],"acid":[17,258],"bacteria":[18,259],"could":[19],"ameliorate":[20],"the":[21,143,172],"lipid":[22,128,156,176,195],"peroxidation":[23],"of":[24,42,125,145,154,174,193],"hepatic":[25,126,267],"mitochondria":[26],"associated":[27],"with":[28,73,83,103,139,164,211,239,256],"cholestatic":[29],"liver":[30],"injury":[31],"due":[32,222],"bile":[34,57,224],"duct":[35,58,225],"ligation.":[36,59],"Rats":[37],"were":[38],"maintained":[39],"on":[40,133,183,202,233,264],"one":[41,63],"five":[43],"diets":[44,61,134,203,234],"for":[45],"3":[46,54],"weeks":[47,55],"before":[48],"being":[49],"operated":[50],"upon":[51],"killed":[53],"after":[56],"included":[62],"deficient":[64],"in":[65,199,219,229],"vitamin":[66],"E":[67],"(control":[68],"diet)":[69],"others":[71],"supplemented":[72],"either":[74],"5%":[75,79],"or":[78],"Bifidobacterium":[84],"longum":[85,141,213,241],"(B.":[86],"longum),":[87],"Lactobacillus":[88],"acidophilus":[89,166],"(L.":[90],"acidophilus),":[91],"Streptococcus":[93],"salivarius":[94],"subsp.":[95],"thermophillus":[96,169],"(S.":[97],"thermophillus).":[98],"Bile":[99],"duct-ligated":[100],"rats,":[101,105],"compared":[102],"sham-operated":[104],"had":[106,179],"higher":[107,113,118,123],"organ":[108,146,184],"weights":[109],"(liver":[110],"spleen),":[112],"serum":[114,119,194],"alkaline":[115],"phosphatase":[116],"activity,":[117,149,187],"bilirubin":[120,150,189],"concentration,":[121,151],"content":[124,153],"mitochondrial":[127,155,175],"hydroperoxide.":[129,157],"rats":[131,200,231],"fed":[132,201,232],"containing":[135,204,235],"B.":[140,212,240],"ameliorated":[142,198,228],"elevation":[144,173,192],"weights,":[147,185],"enzyme":[148,186],"Milk":[158],"L.":[165],"S.":[168,215,246],"also":[170],"suppressed":[171],"hydroperoxide,":[177],"but":[178],"no":[180],"ameliorating":[181],"effects":[182],"concentration.":[190],"hydroperoxide":[196],"thermophillus.":[216],"reduction":[218],"plasma":[220],"\u03b1-tocopherol":[221],"ligation":[226],"those":[230],"as":[242,244],"well":[243],"themophillus.":[247],"These":[248],"results":[249],"suggest":[250],"that":[251],"a":[252,261],"exerts":[260],"beneficial":[262],"effect":[263],"free":[265],"radical-mediated":[266],"injury.":[268]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}