{"id":"https://openalex.org/W2066909002","doi":"https://doi.org/10.1016/j.jocn.2003.09.008","title":"Susceptibility of hippocampus and cerebral cortex to oxidative damage in streptozotocin treated mice: prevention by extracts of Withania somnifera and Aloe vera","display_name":"Susceptibility of hippocampus and cerebral cortex to oxidative damage in streptozotocin treated mice: prevention by extracts of Withania somnifera and Aloe vera","publication_year":2004,"publication_date":"2004-01-23","ids":{"openalex":"https://openalex.org/W2066909002","doi":"https://doi.org/10.1016/j.jocn.2003.09.008","mag":"2066909002","pmid":"https://pubmed.ncbi.nlm.nih.gov/15080956"},"language":"en","primary_location":{"id":"doi:10.1016/j.jocn.2003.09.008","doi":"https://doi.org/10.1016/j.jocn.2003.09.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jocn.2003.09.008","pdf_url":null,"source":{"id":"https://openalex.org/S145023809","display_name":"Journal of Clinical Neuroscience","issn_l":"0967-5868","issn":["0967-5868","1532-2653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025475085","display_name":"Mordhwaj Singh Parihar","orcid":"https://orcid.org/0000-0001-6955-8967","observed_orcids":["https://orcid.org/0000-0001-6955-8967"]},"institutions":[{"id":"https://openalex.org/I86381314","display_name":"Vikram University","ror":"https://ror.org/002k8gm39","country_code":"IN","type":"education","lineage":["https://openalex.org/I86381314"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"M.S Parihar","raw_affiliation_strings":["Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India. mdsparihar@yahoo.com","Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India. mdsparihar@yahoo.com","institution_ids":["https://openalex.org/I86381314"]},{"raw_affiliation_string":"Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India","institution_ids":["https://openalex.org/I86381314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110780402","display_name":"Madhulika Chaudhary","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86381314","display_name":"Vikram University","ror":"https://ror.org/002k8gm39","country_code":"IN","type":"education","lineage":["https://openalex.org/I86381314"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Madhulika Chaudhary","raw_affiliation_strings":["Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India","institution_ids":["https://openalex.org/I86381314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108474534","display_name":"Rajani Shetty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86381314","display_name":"Vikram University","ror":"https://ror.org/002k8gm39","country_code":"IN","type":"education","lineage":["https://openalex.org/I86381314"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rajani Shetty","raw_affiliation_strings":["Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India","institution_ids":["https://openalex.org/I86381314"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002895682","display_name":"Taruna Hemnani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86381314","display_name":"Vikram University","ror":"https://ror.org/002k8gm39","country_code":"IN","type":"education","lineage":["https://openalex.org/I86381314"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Taruna Hemnani","raw_affiliation_strings":["Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Division, Faculty of Life Science, School of Studies in Zoology, Vikram University, Ujjain 456 010, India","institution_ids":["https://openalex.org/I86381314"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5025475085"],"corresponding_institution_ids":["https://openalex.org/I86381314"],"apc_list":{"value":3830,"currency":"USD","value_usd":3830},"apc_paid":null,"fwci":15.5247,"has_fulltext":false,"cited_by_count":123,"citation_normalized_percentile":{"value":0.98483098,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"11","issue":"4","first_page":"397","last_page":"402"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.6230000257492065,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.6230000257492065,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.24740000069141388,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.09880000352859497,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.6700000166893005},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7250000238418579},{"id":"https://openalex.org/keywords/ashwagandha","display_name":"Withania somnifera","score":0.8809999823570251},{"id":"https://openalex.org/keywords/aloe-vera","display_name":"Aloe vera","score":0.9649999737739563},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.7269999980926514},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8709999918937683},{"id":"https://openalex.org/keywords/protein-carbonylation","display_name":"protein carbonylation","score":0.9290000200271606},{"id":"https://openalex.org/keywords/memory-impairment","display_name":"memory impairment","score":0.8799999952316284},{"id":"https://openalex.org/keywords/motor-impairment","display_name":"motor impairment","score":0.9900000095367432},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.746999979019165},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.5849999785423279},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C2780069950","wikidata":"https://www.wikidata.org/wiki/Q852660","display_name":"Withania somnifera","level":3,"score":0.9757112860679626},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.7907286286354065},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.7432981729507446},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5997759103775024},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5516506433486938},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.5123542547225952},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5065232515335083},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4629982113838196},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.4265623092651367},{"id":"https://openalex.org/C2779404486","wikidata":"https://www.wikidata.org/wiki/Q80079","display_name":"Aloe vera","level":2,"score":0.41313907504081726},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.4119799733161926},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.35879963636398315},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33681318163871765},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.2977783679962158},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11017242074012756},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000504","descriptor_name":"Aloe","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013311","descriptor_name":"Streptozocin","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D032341","descriptor_name":"Withania","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D050050","descriptor_name":"Protein Carbonylation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jocn.2003.09.008","doi":"https://doi.org/10.1016/j.jocn.2003.09.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jocn.2003.09.008","pdf_url":null,"source":{"id":"https://openalex.org/S145023809","display_name":"Journal of Clinical Neuroscience","issn_l":"0967-5868","issn":["0967-5868","1532-2653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Neuroscience","raw_type":"journal-article"},{"id":"pmid:15080956","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15080956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320767","display_name":"University Grants Commission","ror":"https://ror.org/04p800546"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W183120241","https://openalex.org/W1507112934","https://openalex.org/W1532672888","https://openalex.org/W1545063508","https://openalex.org/W1546743948","https://openalex.org/W1563559230","https://openalex.org/W1567614586","https://openalex.org/W1775749144","https://openalex.org/W1953115230","https://openalex.org/W1966719975","https://openalex.org/W1983310681","https://openalex.org/W1993975841","https://openalex.org/W2008872268","https://openalex.org/W2013400604","https://openalex.org/W2016293448","https://openalex.org/W2016943722","https://openalex.org/W2021931423","https://openalex.org/W2022766782","https://openalex.org/W2024977010","https://openalex.org/W2026827640","https://openalex.org/W2029115752","https://openalex.org/W2030726807","https://openalex.org/W2033202637","https://openalex.org/W2038804100","https://openalex.org/W2041894106","https://openalex.org/W2044669080","https://openalex.org/W2051049982","https://openalex.org/W2054810384","https://openalex.org/W2056027814","https://openalex.org/W2057042201","https://openalex.org/W2057527861","https://openalex.org/W2062900910","https://openalex.org/W2063660138","https://openalex.org/W2066168019","https://openalex.org/W2071392805","https://openalex.org/W2071621752","https://openalex.org/W2074567032","https://openalex.org/W2078540617","https://openalex.org/W2081852232","https://openalex.org/W2083776482","https://openalex.org/W2083959705","https://openalex.org/W2086355707","https://openalex.org/W2087427054","https://openalex.org/W2091363346","https://openalex.org/W2102166270","https://openalex.org/W2110569594","https://openalex.org/W2112535458","https://openalex.org/W2115337518","https://openalex.org/W2125498249","https://openalex.org/W2130267710","https://openalex.org/W2132335976","https://openalex.org/W2133971230","https://openalex.org/W2170836456","https://openalex.org/W2313212999"],"related_works":["https://openalex.org/W2748475649","https://openalex.org/W2398266159","https://openalex.org/W3208562030","https://openalex.org/W3207701566","https://openalex.org/W3044578806","https://openalex.org/W2548345262","https://openalex.org/W4388737117","https://openalex.org/W2590210085","https://openalex.org/W2762586253","https://openalex.org/W2101870058"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}