{"id":"https://openalex.org/W2066907250","doi":"https://doi.org/10.1021/nl050175c","title":"Programmable DNA Self-Assemblies for Nanoscale Organization of Ligands and Proteins","display_name":"Programmable DNA Self-Assemblies for Nanoscale Organization of Ligands and Proteins","publication_year":2005,"publication_date":"2005-03-08","ids":{"openalex":"https://openalex.org/W2066907250","doi":"https://doi.org/10.1021/nl050175c","mag":"2066907250","pmid":"https://pubmed.ncbi.nlm.nih.gov/15826117"},"language":"en","primary_location":{"id":"doi:10.1021/nl050175c","doi":"https://doi.org/10.1021/nl050175c","is_oa":false,"landing_page_url":"https://doi.org/10.1021/nl050175c","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100758572","display_name":"Sung Ha Park","orcid":"https://orcid.org/0000-0002-0256-3363","observed_orcids":["https://orcid.org/0000-0002-0256-3363"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sung Ha Park","raw_affiliation_strings":["Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059621249","display_name":"Peng Yin","orcid":"https://orcid.org/0000-0002-2769-6357","observed_orcids":["https://orcid.org/0000-0002-2769-6357"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peng Yin","raw_affiliation_strings":["Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100389794","display_name":"Yan Liu","orcid":"https://orcid.org/0000-0003-0906-2606","observed_orcids":["https://orcid.org/0000-0003-0906-2606"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Liu","raw_affiliation_strings":["Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","CLAS-NS: Molecular Sciences, School of (SMS)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"]},{"raw_affiliation_string":"CLAS-NS: Molecular Sciences, School of (SMS)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007364145","display_name":"John H. Reif","orcid":"https://orcid.org/0000-0002-9096-2056","observed_orcids":["https://orcid.org/0000-0002-9096-2056"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H. Reif","raw_affiliation_strings":["Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036574954","display_name":"Thomas H. LaBean","orcid":"https://orcid.org/0000-0002-6739-2059","observed_orcids":["https://orcid.org/0000-0002-6739-2059"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas H. LaBean","raw_affiliation_strings":["Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064979753","display_name":"Hao Yan","orcid":"https://orcid.org/0000-0001-7397-9852","observed_orcids":["https://orcid.org/0000-0001-7397-9852"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hao Yan","raw_affiliation_strings":["Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, North Carolina 27708, and Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5064979753"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I55732556"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":9.0954,"has_fulltext":false,"cited_by_count":287,"citation_normalized_percentile":{"value":0.98987763,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"5","issue":"4","first_page":"729","last_page":"733"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-self-assembly","display_name":"DNA self-assembly","score":0.9779999852180481},{"id":"https://openalex.org/keywords/protein-microarrays","display_name":"protein microarrays","score":0.6470000147819519},{"id":"https://openalex.org/keywords/streptavidin","display_name":"streptavidin","score":0.9789999723434448},{"id":"https://openalex.org/keywords/nanogrid","display_name":"nanogrid","score":0.8640000224113464}],"concepts":[{"id":"https://openalex.org/C82714645","wikidata":"https://www.wikidata.org/wiki/Q438331","display_name":"Template","level":2,"score":0.8297567367553711},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6658658385276794},{"id":"https://openalex.org/C26856880","wikidata":"https://www.wikidata.org/wiki/Q910150","display_name":"Self-assembly","level":2,"score":0.6248669028282166},{"id":"https://openalex.org/C2780728851","wikidata":"https://www.wikidata.org/wiki/Q468402","display_name":"Tile","level":2,"score":0.5877924561500549},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5815379619598389},{"id":"https://openalex.org/C45206210","wikidata":"https://www.wikidata.org/wiki/Q2415817","display_name":"Nanoscopic scale","level":2,"score":0.5809906125068665},{"id":"https://openalex.org/C2776190903","wikidata":"https://www.wikidata.org/wiki/Q421817","display_name":"Streptavidin","level":3,"score":0.5458567142486572},{"id":"https://openalex.org/C118630614","wikidata":"https://www.wikidata.org/wiki/Q1154606","display_name":"DNA origami","level":3,"score":0.518608808517456},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.44534602761268616},{"id":"https://openalex.org/C129275984","wikidata":"https://www.wikidata.org/wiki/Q602847","display_name":"DNA nanotechnology","level":3,"score":0.41431164741516113},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3280808925628662},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3084654211997986},{"id":"https://openalex.org/C186187911","wikidata":"https://www.wikidata.org/wiki/Q1093894","display_name":"Nanostructure","level":2,"score":0.2486095428466797},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17700812220573425},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10984227061271667},{"id":"https://openalex.org/C2778204606","wikidata":"https://www.wikidata.org/wiki/Q181354","display_name":"Biotin","level":2,"score":0.07685774564743042},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013698","descriptor_name":"Templates, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018625","descriptor_name":"Microscopy, Atomic Force","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1021/nl050175c","doi":"https://doi.org/10.1021/nl050175c","is_oa":false,"landing_page_url":"https://doi.org/10.1021/nl050175c","pdf_url":null,"source":{"id":"https://openalex.org/S143846845","display_name":"Nano Letters","issn_l":"1530-6984","issn":["1530-6984","1530-6992"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano Letters","raw_type":"journal-article"},{"id":"pmid:15826117","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15826117","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nano letters","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.118.4117","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.118.4117","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://pengyin.org/paper/dnaAttach/2005.nanolett.attach.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.131.9477","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.131.9477","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cs.duke.edu/~thl/papers/NanoTrack.2005.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.151.9027","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.151.9027","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cs.duke.edu/~reif/paper/park/prog.ligand/prog.ligand.pub.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1507168345","https://openalex.org/W1567090568","https://openalex.org/W2011108001","https://openalex.org/W2020023238","https://openalex.org/W2020437858","https://openalex.org/W2027804504","https://openalex.org/W2041857964","https://openalex.org/W2043381968","https://openalex.org/W2049106847","https://openalex.org/W2062802768","https://openalex.org/W2064773175","https://openalex.org/W2068744615","https://openalex.org/W2071836755","https://openalex.org/W2072687635","https://openalex.org/W2076051065","https://openalex.org/W2105631710","https://openalex.org/W2156240315"],"related_works":["https://openalex.org/W2043951705","https://openalex.org/W2072687635","https://openalex.org/W7096358858","https://openalex.org/W2169209269","https://openalex.org/W2268362283","https://openalex.org/W2134069036","https://openalex.org/W2157446319","https://openalex.org/W2034268042","https://openalex.org/W1999380198","https://openalex.org/W1996881864"],"abstract_inverted_index":{"We":[0],"demonstrate":[1],"the":[2,14,24],"precise":[3],"control":[4],"of":[5,16,26,42],"periodic":[6,29],"spacing":[7],"between":[8],"individual":[9],"protein":[10,44],"molecules":[11],"by":[12],"programming":[13],"self-assembly":[15,41],"DNA":[17,30],"tile":[18],"templates.":[19],"In":[20],"particular,":[21],"we":[22],"report":[23],"application":[25],"two":[27],"self-assembled":[28],"structures,":[31],"two-dimensional":[32],"nanogrids,":[33],"and":[34],"one-dimensional":[35],"nanotrack,":[36],"as":[37],"template":[38],"for":[39],"programmable":[40],"streptavidin":[43],"arrays":[45],"with":[46],"controlled":[47],"density.":[48]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":18},{"year":2013,"cited_by_count":22},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}