{"id":"https://openalex.org/W2066485945","doi":"https://doi.org/10.1111/j.1399-0004.2006.00665.x","title":"Risk\u2010reducing surgery, screening and chemoprevention practices of BRCA1 and BRCA2 mutation carriers: a prospective cohort study","display_name":"Risk\u2010reducing surgery, screening and chemoprevention practices of BRCA1 and BRCA2 mutation carriers: a prospective cohort study","publication_year":2006,"publication_date":"2006-08-10","ids":{"openalex":"https://openalex.org/W2066485945","doi":"https://doi.org/10.1111/j.1399-0004.2006.00665.x","mag":"2066485945","pmid":"https://pubmed.ncbi.nlm.nih.gov/16922722"},"language":"en","primary_location":{"id":"doi:10.1111/j.1399-0004.2006.00665.x","doi":"https://doi.org/10.1111/j.1399-0004.2006.00665.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1399-0004.2006.00665.x","pdf_url":null,"source":{"id":"https://openalex.org/S4954800","display_name":"Clinical Genetics","issn_l":"0009-9163","issn":["0009-9163","1399-0004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039888939","display_name":"Kelly\u2010Anne Phillips","orcid":"https://orcid.org/0000-0002-0475-1771","observed_orcids":["https://orcid.org/0000-0002-0475-1771"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I2800555584","display_name":"Peter MacCallum Cancer Centre","ror":"https://ror.org/02a8bt934","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800555584"]},{"id":"https://openalex.org/I4210087110","display_name":"St Vincent's Hospital Melbourne","ror":"https://ror.org/001kjn539","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210087110","https://openalex.org/I4210098850"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"K\u2010A Phillips","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, University of Melbourne Department of Medicine, St Vincent's Hospital, Victoria, NSW, Australia. kelly.phillips@petermac.org","Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","University of Melbourne Department of Medicine, St Vincent's Hospital, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, University of Melbourne Department of Medicine, St Vincent's Hospital, Victoria, NSW, Australia. kelly.phillips@petermac.org","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800555584","https://openalex.org/I4210087110"]},{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","institution_ids":["https://openalex.org/I2800555584"]},{"raw_affiliation_string":"University of Melbourne Department of Medicine, St Vincent's Hospital, Victoria","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210087110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090508414","display_name":"Mark A. Jenkins","orcid":"https://orcid.org/0000-0002-8964-6160","observed_orcids":["https://orcid.org/0000-0002-8964-6160"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"MA Jenkins","raw_affiliation_strings":["Centre for Molecular, Environmental, Genetic & Analytic Epidemiology, University of Melbourne, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Molecular, Environmental, Genetic & Analytic Epidemiology, University of Melbourne, Victoria","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079753000","display_name":"Geoffrey John Lindeman","orcid":"https://orcid.org/0000-0001-9386-2416","observed_orcids":["https://orcid.org/0000-0001-9386-2416"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"GJ Lindeman","raw_affiliation_strings":["Department of Haematology and Medical Oncology, Royal Melbourne Hospital, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology and Medical Oncology, Royal Melbourne Hospital, Victoria","institution_ids":["https://openalex.org/I1320473756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111797139","display_name":"SA McLachlan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I2800555584","display_name":"Peter MacCallum Cancer Centre","ror":"https://ror.org/02a8bt934","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800555584"]},{"id":"https://openalex.org/I4210087110","display_name":"St Vincent's Hospital Melbourne","ror":"https://ror.org/001kjn539","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210087110","https://openalex.org/I4210098850"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"SA McLachlan","raw_affiliation_strings":["Department of Medical Oncology, St Vincent\u2019s Hospital, Victoria","Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","University of Melbourne Department of Medicine, St Vincent\u2019s Hospital, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, St Vincent\u2019s Hospital, Victoria","institution_ids":["https://openalex.org/I4210087110"]},{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","institution_ids":["https://openalex.org/I2800555584"]},{"raw_affiliation_string":"University of Melbourne Department of Medicine, St Vincent\u2019s Hospital, Victoria","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210087110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027778821","display_name":"Joanne M. McKinley","orcid":"https://orcid.org/0000-0001-5572-0177","observed_orcids":["https://orcid.org/0000-0001-5572-0177"]},"institutions":[{"id":"https://openalex.org/I2800555584","display_name":"Peter MacCallum Cancer Centre","ror":"https://ror.org/02a8bt934","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800555584"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"JM McKinley","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","institution_ids":["https://openalex.org/I2800555584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077921172","display_name":"Prue C. Weideman","orcid":"https://orcid.org/0000-0002-3672-5201","observed_orcids":["https://orcid.org/0000-0002-3672-5201"]},"institutions":[{"id":"https://openalex.org/I2800555584","display_name":"Peter MacCallum Cancer Centre","ror":"https://ror.org/02a8bt934","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800555584"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"PC Weideman","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","institution_ids":["https://openalex.org/I2800555584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023667273","display_name":"John Llewelyn Hopper","orcid":"https://orcid.org/0000-0002-8567-173X","observed_orcids":["https://orcid.org/0000-0002-8567-173X","https://orcid.org/0000-0003-2445-8043"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"JL Hopper","raw_affiliation_strings":["Centre for Molecular, Environmental, Genetic & Analytic Epidemiology, University of Melbourne, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Molecular, Environmental, Genetic & Analytic Epidemiology, University of Melbourne, Victoria","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102126528","display_name":"ML Friedlander","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108821","display_name":"Prince of Wales Hospital","ror":"https://ror.org/022arq532","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210108821"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"ML Friedlander","raw_affiliation_strings":["Department of Medical Oncology, Prince of Wales Hospital, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Prince of Wales Hospital, NSW, Australia","institution_ids":["https://openalex.org/I4210108821"]}]},{"author_position":"last","author":{"id":null,"display_name":"kConFab Investigators","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800555584","display_name":"Peter MacCallum Cancer Centre","ror":"https://ror.org/02a8bt934","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800555584"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"kConFab Investigators","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria","institution_ids":["https://openalex.org/I2800555584"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5039888939"],"corresponding_institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800555584","https://openalex.org/I4210087110"],"apc_list":{"value":4980,"currency":"USD","value_usd":4980},"apc_paid":null,"fwci":3.5441,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.93585601,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"70","issue":"3","first_page":"198","last_page":"206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13544","display_name":"Women's cancer prevention and management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brca1-mutation-carriers","display_name":"BRCA1 mutation carriers","score":0.9779999852180481},{"id":"https://openalex.org/keywords/brca2-mutation-carriers","display_name":"BRCA2 mutation carriers","score":1.0},{"id":"https://openalex.org/keywords/hereditary-breast-and-ovarian-cancer-syndrome","display_name":"hereditary breast and ovarian cancer","score":0.8429999947547913},{"id":"https://openalex.org/keywords/prophylactic-surgery","display_name":"prophylactic surgery","score":0.9620000123977661},{"id":"https://openalex.org/keywords/bilateral-mastectomy","display_name":"bilateral mastectomy","score":0.6769999861717224},{"id":"https://openalex.org/keywords/bilateral-oophorectomy","display_name":"bilateral oophorectomy","score":0.9729999899864197},{"id":"https://openalex.org/keywords/tumor-screening","display_name":"cancer screening","score":0.7260000109672546},{"id":"https://openalex.org/keywords/breast-self-examination","display_name":"breast self-examination","score":0.847000002861023},{"id":"https://openalex.org/keywords/clinical-breast-examination","display_name":"clinical breast examination","score":0.796999990940094},{"id":"https://openalex.org/keywords/mammography","display_name":"mammography","score":0.9940000176429749},{"id":"https://openalex.org/keywords/transvaginal-ultrasound","display_name":"transvaginal ultrasound","score":0.9670000076293945},{"id":"https://openalex.org/keywords/ca125","display_name":"CA125","score":0.9900000095367432},{"id":"https://openalex.org/keywords/chemoprevention","display_name":"chemoprevention","score":0.9639999866485596},{"id":"https://openalex.org/keywords/genetic-testing-uptake","display_name":"genetic testing uptake","score":0.6019999980926514},{"id":"https://openalex.org/keywords/screening-utilization","display_name":"screening utilization","score":0.3160000145435333}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8743345141410828},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.6630909442901611},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6111399531364441},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5617276430130005},{"id":"https://openalex.org/C2910039337","wikidata":"https://www.wikidata.org/wiki/Q16394661","display_name":"Prophylactic Mastectomy","level":5,"score":0.5602220892906189},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5389886498451233},{"id":"https://openalex.org/C2780194787","wikidata":"https://www.wikidata.org/wiki/Q4836333","display_name":"BRCA mutation","level":4,"score":0.5237507820129395},{"id":"https://openalex.org/C2777696064","wikidata":"https://www.wikidata.org/wiki/Q1751597","display_name":"Oophorectomy","level":3,"score":0.4865785837173462},{"id":"https://openalex.org/C2910584544","wikidata":"https://www.wikidata.org/wiki/Q65042430","display_name":"Prophylactic Surgery","level":4,"score":0.46924543380737305},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.46066775918006897},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4448513984680176},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.42866942286491394},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.41131359338760376},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4043530821800232},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3967803418636322},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.36173614859580994},{"id":"https://openalex.org/C2777757722","wikidata":"https://www.wikidata.org/wiki/Q848318","display_name":"Mastectomy","level":4,"score":0.3525286912918091},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.332187294960022},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3221656084060669},{"id":"https://openalex.org/C2779494336","wikidata":"https://www.wikidata.org/wiki/Q550675","display_name":"Hysterectomy","level":2,"score":0.18587514758110046},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08030310273170471},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006579","descriptor_name":"Heterozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006580","descriptor_name":"Genetic Carrier Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008327","descriptor_name":"Mammography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008408","descriptor_name":"Mastectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010052","descriptor_name":"Ovariectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018890","descriptor_name":"Chemoprevention","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019398","descriptor_name":"Genes, BRCA1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024522","descriptor_name":"Genes, BRCA2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1399-0004.2006.00665.x","doi":"https://doi.org/10.1111/j.1399-0004.2006.00665.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1399-0004.2006.00665.x","pdf_url":null,"source":{"id":"https://openalex.org/S4954800","display_name":"Clinical Genetics","issn_l":"0009-9163","issn":["0009-9163","1399-0004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Genetics","raw_type":"journal-article"},{"id":"pmid:16922722","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16922722","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W105210906","https://openalex.org/W1201749067","https://openalex.org/W1493144403","https://openalex.org/W1534216133","https://openalex.org/W1596487580","https://openalex.org/W1901472791","https://openalex.org/W1943662524","https://openalex.org/W1961326267","https://openalex.org/W1984320393","https://openalex.org/W1994789648","https://openalex.org/W1998197289","https://openalex.org/W2006202627","https://openalex.org/W2008083399","https://openalex.org/W2009074196","https://openalex.org/W2038793520","https://openalex.org/W2040438137","https://openalex.org/W2042749048","https://openalex.org/W2043853870","https://openalex.org/W2045733577","https://openalex.org/W2046809735","https://openalex.org/W2053277023","https://openalex.org/W2090365917","https://openalex.org/W2100995246","https://openalex.org/W2101699473","https://openalex.org/W2105346300","https://openalex.org/W2109764430","https://openalex.org/W2121935084","https://openalex.org/W2127379638","https://openalex.org/W2129990146","https://openalex.org/W2138742383","https://openalex.org/W2143698296","https://openalex.org/W2143940059","https://openalex.org/W2144624092","https://openalex.org/W2147058464","https://openalex.org/W2161076410","https://openalex.org/W2161764786","https://openalex.org/W2164059351","https://openalex.org/W2165277279","https://openalex.org/W2183493782","https://openalex.org/W2415943205"],"related_works":["https://openalex.org/W1901472791","https://openalex.org/W2793466621","https://openalex.org/W4404059733","https://openalex.org/W2938903157","https://openalex.org/W2111533289","https://openalex.org/W2040438137","https://openalex.org/W2766605627","https://openalex.org/W2325204202","https://openalex.org/W4392874206","https://openalex.org/W957812480"],"abstract_inverted_index":{"This":[0],"study":[1],"prospectively":[2],"evaluated":[3],"the":[4,170],"utilization":[5],"of":[6,15,141,172],"cancer":[7],"risk":[8],"management":[9],"strategies":[10],"in":[11],"a":[12,22,137,181],"multi-institutional":[13],"cohort":[14],"BRCA1":[16],"and":[17,63,67,81,90,115,120,128,144,161,163,180],"BRCA2":[18],"mutation":[19,29,38,45,107,151,173],"carriers":[20,174],"using":[21],"self-report":[23],"questionnaire.":[24],"Of":[25,40],"142":[26],"unaffected":[27],"female":[28],"carriers,":[30],"70":[31],"(49%)":[32],"had":[33,53,69,96,122],"elected":[34,102],"to":[35,104],"receive":[36,105],"their":[37,44,106],"result.":[39],"those":[41],"who":[42,101],"knew":[43],"result,":[46,108],"11%":[47],"underwent":[48,110,113],"bilateral":[49,54],"mastectomy":[50],"(BM),":[51],"29%":[52],"oophorectomy":[55],"(BO),":[56],"78%":[57],"performed":[58],"regular":[59,123,187],"breast":[60,74],"self-examination":[61],"(BSE),":[62],"80%,":[64],"89%,":[65],"67%,":[66],"0%":[68,109,121],"at":[70],"least":[71],"annual":[72],"clinical":[73,138],"examination":[75],"(CBE),":[76],"mammography,":[77,126],"transvaginal":[78],"ultrasound":[79],"(TVU),":[80],"CA125,":[82,129],"respectively.":[83,130],"A":[84],"further":[85],"20%,":[86],"7%,":[87,119],"0%,":[88],"21%,":[89],"75%,":[91],"respectively,":[92],"reported":[93],"never":[94],"having":[95],"these":[97],"tests.":[98,189],"For":[99],"women":[100],"not":[103,185],"BM,":[111],"6%":[112],"BO,":[114],"77%,":[116],"42%,":[117],"56%,":[118],"BSE,":[124],"CBE,":[125],"TVU,":[127],"Only":[131],"one":[132],"woman":[133],"used":[134],"chemoprevention":[135,179],"outside":[136],"trial.":[139],"Uptake":[140],"prophylactic":[142],"surgery":[143,177],"screening":[145],"was":[146],"associated":[147],"with":[148],"knowing":[149],"one's":[150],"status":[152],"(for":[153,159,165],"all":[154],"behaviors":[155],"except":[156],"BSE),":[157],"age":[158],"BO":[160],"CBE)":[162],"residence":[164],"mammography).":[166],"In":[167],"this":[168],"cohort,":[169],"minority":[171,183],"utilized":[175],"risk-reducing":[176],"or":[178],"substantial":[182],"were":[184],"undergoing":[186],"cancer-screening":[188]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}