{"id":"https://openalex.org/W2066451602","doi":"https://doi.org/10.1016/0090-1229(85)90036-4","title":"Defects in mononuclear phagocytic system (MPS) function in autoimmune MRL-lpr/lpr mice","display_name":"Defects in mononuclear phagocytic system (MPS) function in autoimmune MRL-lpr/lpr mice","publication_year":1985,"publication_date":"1985-07-01","ids":{"openalex":"https://openalex.org/W2066451602","doi":"https://doi.org/10.1016/0090-1229(85)90036-4","mag":"2066451602","pmid":"https://pubmed.ncbi.nlm.nih.gov/3874027"},"language":"en","primary_location":{"id":"doi:10.1016/0090-1229(85)90036-4","doi":"https://doi.org/10.1016/0090-1229(85)90036-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0090-1229(85)90036-4","pdf_url":null,"source":{"id":"https://openalex.org/S174675264","display_name":"Clinical Immunology and Immunopathology","issn_l":"0090-1229","issn":["0090-1229","1090-2341"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Immunology and Immunopathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019262450","display_name":"Fred S. Jones","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210139568","display_name":"Durham VA Medical Center","ror":"https://ror.org/034adnw64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210119589","https://openalex.org/I4210139568","https://openalex.org/I4210159720"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fred S. Jones","raw_affiliation_strings":["Department of Medicine, Durham Veterans Administration Hospital, Durham, North Carolina 27710 USA","Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Durham Veterans Administration Hospital, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I4210139568"]},{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015062757","display_name":"David S. Pisetsky","orcid":"https://orcid.org/0000-0002-3539-5351","observed_orcids":["https://orcid.org/0000-0002-3539-5351"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210139568","display_name":"Durham VA Medical Center","ror":"https://ror.org/034adnw64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210119589","https://openalex.org/I4210139568","https://openalex.org/I4210159720"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David S. Pisetsky","raw_affiliation_strings":["Department of Medicine, Durham Veterans Administration Hospital, Durham, North Carolina 27710 USA","Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Durham Veterans Administration Hospital, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I4210139568"]},{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005077693","display_name":"Roger J. Kurlander","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210139568","display_name":"Durham VA Medical Center","ror":"https://ror.org/034adnw64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210119589","https://openalex.org/I4210139568","https://openalex.org/I4210159720"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Roger J. Kurlander","raw_affiliation_strings":["Department of Medicine, Durham Veterans Administration Hospital, Durham, North Carolina 27710 USA","Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Durham Veterans Administration Hospital, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I4210139568"]},{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005077693"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210139568"],"apc_list":null,"apc_paid":null,"fwci":1.1953,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.78865325,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"36","issue":"1","first_page":"30","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mrl-lpr-mice","display_name":"MRL/lpr mice","score":0.9120000004768372},{"id":"https://openalex.org/keywords/reticuloendothelial-system","display_name":"reticuloendothelial system","score":0.8809999823570251},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.875},{"id":"https://openalex.org/keywords/immune-complex-clearance","display_name":"immune complex clearance","score":0.7739999890327454},{"id":"https://openalex.org/keywords/liver-sequestration","display_name":"liver sequestration","score":0.7620000243186951},{"id":"https://openalex.org/keywords/anti-dna-antibodies","display_name":"anti-DNA antibodies","score":0.9390000104904175},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C84951073","wikidata":"https://www.wikidata.org/wiki/Q2379153","display_name":"Congenic","level":3,"score":0.8282759189605713},{"id":"https://openalex.org/C19702531","wikidata":"https://www.wikidata.org/wiki/Q929966","display_name":"Mononuclear phagocyte system","level":2,"score":0.6534826755523682},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.628515362739563},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.5764844417572021},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5562552809715271},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5235697627067566},{"id":"https://openalex.org/C2778474638","wikidata":"https://www.wikidata.org/wiki/Q575241","display_name":"Immune complex","level":3,"score":0.4767281115055084},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.46641480922698975},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4556875228881836},{"id":"https://openalex.org/C2775915377","wikidata":"https://www.wikidata.org/wiki/Q188297","display_name":"Lupus erythematosus","level":3,"score":0.4464525282382965},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.43914031982421875},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3787209093570709},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35894009470939636},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2320515513420105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.183026522397995},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1539475917816162},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.11810657382011414},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000974","descriptor_name":"Antibodies, Antinuclear","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010586","descriptor_name":"Phagocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0090-1229(85)90036-4","doi":"https://doi.org/10.1016/0090-1229(85)90036-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0090-1229(85)90036-4","pdf_url":null,"source":{"id":"https://openalex.org/S174675264","display_name":"Clinical Immunology and Immunopathology","issn_l":"0090-1229","issn":["0090-1229","1090-2341"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Immunology and Immunopathology","raw_type":"journal-article"},{"id":"pmid:3874027","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3874027","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical immunology and immunopathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8399999737739563,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5491183538","display_name":null,"funder_award_id":"5R01AI18073","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8423395843","display_name":"T CELL PHAGOCYTE INTERACTION IN ANTIMICROBIAL IMMUNITY","funder_award_id":"5r01ai018073-14","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1487638043","https://openalex.org/W1493302263","https://openalex.org/W1519791715","https://openalex.org/W1558721940","https://openalex.org/W1563998607","https://openalex.org/W1638118783","https://openalex.org/W1775749144","https://openalex.org/W1890911233","https://openalex.org/W1900248812","https://openalex.org/W1910348797","https://openalex.org/W1920920641","https://openalex.org/W1955828664","https://openalex.org/W1988054879","https://openalex.org/W2027534059","https://openalex.org/W2031031326","https://openalex.org/W2058483881","https://openalex.org/W2072145209","https://openalex.org/W2080580789","https://openalex.org/W2085000731","https://openalex.org/W2102162360","https://openalex.org/W2134452794","https://openalex.org/W2134909403","https://openalex.org/W2142360671","https://openalex.org/W2313945915","https://openalex.org/W2315955202","https://openalex.org/W2331698384","https://openalex.org/W2341400992","https://openalex.org/W2413808702","https://openalex.org/W4313313436","https://openalex.org/W4313317795"],"related_works":["https://openalex.org/W1486578103","https://openalex.org/W7100681346","https://openalex.org/W2419545535","https://openalex.org/W1968816324","https://openalex.org/W1978493949","https://openalex.org/W2411578202","https://openalex.org/W2147070021","https://openalex.org/W2411528352","https://openalex.org/W2288298497","https://openalex.org/W1963798725"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}