{"id":"https://openalex.org/W2066094290","doi":"https://doi.org/10.1002/hep.24622","title":"Intensive care of the patient with cirrhosis","display_name":"Intensive care of the patient with cirrhosis","publication_year":2011,"publication_date":"2011-08-31","ids":{"openalex":"https://openalex.org/W2066094290","doi":"https://doi.org/10.1002/hep.24622","mag":"2066094290","pmid":"https://pubmed.ncbi.nlm.nih.gov/21898477"},"language":"en","primary_location":{"id":"doi:10.1002/hep.24622","doi":"https://doi.org/10.1002/hep.24622","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hep.24622","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.24622","source":{"id":"https://openalex.org/S156174673","display_name":"Hepatology","issn_l":"0270-9139","issn":["0270-9139","1527-3350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.24622","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060242274","display_name":"Jody C. Olson","orcid":"https://orcid.org/0000-0003-2818-4959","observed_orcids":["https://orcid.org/0000-0003-2818-4959"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jody C. Olson","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA","Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009574999","display_name":"Julia Alexis Wendon","orcid":"https://orcid.org/0000-0003-0226-6366","observed_orcids":["https://orcid.org/0000-0003-0226-6366"]},"institutions":[{"id":"https://openalex.org/I4210113441","display_name":"Kings Health Partners","ror":"https://ror.org/01xcsye48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210113441"]},{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julia A. Wendon","raw_affiliation_strings":["Kings College, Kings Health Partners, Kings College Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kings College, Kings Health Partners, Kings College Hospital, London, UK","institution_ids":["https://openalex.org/I4210113441","https://openalex.org/I4210153400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103696949","display_name":"David J. Kramer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Kramer","raw_affiliation_strings":["Mayo Clinic, Jacksonville, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Jacksonville, FL","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066290707","display_name":"Vicente Arroyo","orcid":"https://orcid.org/0000-0002-2728-1848","observed_orcids":["https://orcid.org/0000-0002-2728-1848"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Vicente Arroyo","raw_affiliation_strings":["University of Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047324691","display_name":"Rajiv Jalan","orcid":"https://orcid.org/0000-0002-7747-4015","observed_orcids":["https://orcid.org/0000-0002-7747-4015"]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rajiv Jalan","raw_affiliation_strings":["University College London Institute of Hepatology, Royal Free Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University College London Institute of Hepatology, Royal Free Hospital, London, UK","institution_ids":["https://openalex.org/I2801138448","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018974631","display_name":"Guadalupe Garc\u00eda\u2013Tsao","orcid":"https://orcid.org/0000-0002-6175-8216","observed_orcids":["https://orcid.org/0000-0002-6175-8216","https://orcid.org/0000-0001-8371-4524"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guadalupe Garcia-Tsao","raw_affiliation_strings":["Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012239800","display_name":"Patrick S. Kamath","orcid":"https://orcid.org/0000-0002-7888-1165","observed_orcids":["https://orcid.org/0000-0002-7888-1165"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patrick S. Kamath","raw_affiliation_strings":["Mayo Clinic, Rochester, MN","fax: 507-284-1649"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"fax: 507-284-1649","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5012239800"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":2900,"currency":"USD","value_usd":2900},"apc_paid":null,"fwci":2.1722,"has_fulltext":true,"cited_by_count":251,"citation_normalized_percentile":{"value":0.90517241,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"54","issue":"5","first_page":"1864","last_page":"1872"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/critical-care","display_name":"intensive care","score":0.6909999847412109},{"id":"https://openalex.org/keywords/multiple-organ-failure","display_name":"multiple organ failure","score":0.9789999723434448},{"id":"https://openalex.org/keywords/viral-hepatitis","display_name":"viral hepatitis","score":0.7379999756813049},{"id":"https://openalex.org/keywords/drug-induced-hepatitis","display_name":"drug-induced hepatitis","score":0.6489999890327454},{"id":"https://openalex.org/keywords/alcoholic-hepatitis","display_name":"alcoholic hepatitis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/variceal-bleeding","display_name":"variceal bleeding","score":0.9900000095367432},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.7519999742507935},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.6880000233650208},{"id":"https://openalex.org/keywords/sofa-score","display_name":"SOFA score","score":0.6729999780654907},{"id":"https://openalex.org/keywords/child-pugh-score","display_name":"Child-Pugh score","score":0.9610000252723694},{"id":"https://openalex.org/keywords/meld-score","display_name":"MELD score","score":0.9779999852180481},{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.8980000019073486},{"id":"https://openalex.org/keywords/artificial-liver-support","display_name":"artificial liver support","score":0.8059999942779541},{"id":"https://openalex.org/keywords/bioartificial-liver-support","display_name":"bioartificial liver support","score":0.9539999961853027},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.3869999945163727}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9053181409835815},{"id":"https://openalex.org/C41260117","wikidata":"https://www.wikidata.org/wiki/Q668064","display_name":"Hepatology","level":2,"score":0.7761381268501282},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.676722526550293},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6368728876113892},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.5999759435653687},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5673182010650635},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.5659109950065613},{"id":"https://openalex.org/C2780732942","wikidata":"https://www.wikidata.org/wiki/Q3144986","display_name":"Alcoholic hepatitis","level":4,"score":0.5537770390510559},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.5406875014305115},{"id":"https://openalex.org/C2987404301","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care","level":2,"score":0.5038458704948425},{"id":"https://openalex.org/C2778426790","wikidata":"https://www.wikidata.org/wiki/Q1649580","display_name":"Organ dysfunction","level":3,"score":0.4990706443786621},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.4894951581954956},{"id":"https://openalex.org/C2777575235","wikidata":"https://www.wikidata.org/wiki/Q558404","display_name":"Alcoholic liver disease","level":3,"score":0.47807788848876953},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.3569311499595642}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D017093","descriptor_name":"Liver Failure","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D017093","descriptor_name":"Liver Failure","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/hep.24622","doi":"https://doi.org/10.1002/hep.24622","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hep.24622","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.24622","source":{"id":"https://openalex.org/S156174673","display_name":"Hepatology","issn_l":"0270-9139","issn":["0270-9139","1527-3350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology","raw_type":"journal-article"},{"id":"pmid:21898477","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21898477","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology (Baltimore, Md.)","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1389574","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1389574/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HEPATOLOGY , 54 (5) pp. 1864-1872. (2011)","raw_type":"Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/6638fe82-6ca2-47e9-bb4f-1fe4eee03906","doi":null,"is_oa":false,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/6638fe82-6ca2-47e9-bb4f-1fe4eee03906","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Olson, J C, Wendon, J A, Kramer, D J, Arroyo, V, Jalan, R, Garcia-Tsao, G & Kamath, P S 2011, 'Intensive Care of the Patient with Cirrhosis', Hepatology, vol. 54, no. 5, pp. 1864-1872. https://doi.org/10.1002/hep.24622","raw_type":"info:eu-repo/semantics/review"}],"best_oa_location":{"id":"doi:10.1002/hep.24622","doi":"https://doi.org/10.1002/hep.24622","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hep.24622","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.24622","source":{"id":"https://openalex.org/S156174673","display_name":"Hepatology","issn_l":"0270-9139","issn":["0270-9139","1527-3350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2066094290.pdf","grobid_xml":"https://content.openalex.org/works/W2066094290.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W30933266","https://openalex.org/W1974873560","https://openalex.org/W1977626961","https://openalex.org/W1978909118","https://openalex.org/W1983906125","https://openalex.org/W1994796509","https://openalex.org/W2012122289","https://openalex.org/W2012746560","https://openalex.org/W2013221039","https://openalex.org/W2017557941","https://openalex.org/W2018393523","https://openalex.org/W2019081326","https://openalex.org/W2022183629","https://openalex.org/W2027230796","https://openalex.org/W2028213315","https://openalex.org/W2032621355","https://openalex.org/W2049187517","https://openalex.org/W2050171549","https://openalex.org/W2054168229","https://openalex.org/W2060123467","https://openalex.org/W2064769063","https://openalex.org/W2068297810","https://openalex.org/W2072994640","https://openalex.org/W2079551812","https://openalex.org/W2079602940","https://openalex.org/W2082879426","https://openalex.org/W2082913035","https://openalex.org/W2099360240","https://openalex.org/W2105269204","https://openalex.org/W2110686105","https://openalex.org/W2115534023","https://openalex.org/W2134599653","https://openalex.org/W2139603170","https://openalex.org/W2139801997","https://openalex.org/W2145053281","https://openalex.org/W2157556100","https://openalex.org/W2160691650","https://openalex.org/W2166660180","https://openalex.org/W2171716651","https://openalex.org/W2231355004","https://openalex.org/W2597070792","https://openalex.org/W2791977642","https://openalex.org/W4327766729"],"related_works":["https://openalex.org/W1984975012","https://openalex.org/W1984772664","https://openalex.org/W3209184680","https://openalex.org/W4254561655","https://openalex.org/W2084834158","https://openalex.org/W10719249","https://openalex.org/W2037956453","https://openalex.org/W2019142596","https://openalex.org/W1987572249","https://openalex.org/W2055934763"],"abstract_inverted_index":{"Acute":[0],"deterioration":[1,108,146],"of":[2,59,68,79,84,114,118,169],"patients":[3,122,163,184],"with":[4,39,55,106,123,132],"cirrhosis":[5,40],"manifests":[6],"as":[7],"multiple":[8,125],"organ":[9,72,98,126],"failure":[10,73,127],"requiring":[11],"admission":[12,52],"to":[13,164,181],"an":[14],"intensive":[15,43],"care":[16,44],"unit.":[17],"Precipitating":[18],"events":[19],"may":[20],"be":[21],"viral":[22],"hepatitis,":[23],"typically":[24],"in":[25,35,41,109,134,147,161,174,201],"Asia,":[26],"and":[27,32,50,81,137,153,167,188],"drug":[28],"or":[29,88],"alcoholic":[30],"hepatitis":[31],"variceal":[33],"hemorrhage":[34],"the":[36,42,66,77,82,101,115],"West.":[37],"Patients":[38],"unit":[45],"have":[46,193],"a":[47,56,129,185],"high":[48],"mortality,":[49],"each":[51],"is":[53,63,100,104,141,159,172,179],"associated":[54,105],"mean":[57],"charge":[58],"US":[60],"$116,200.":[61],"Prognosis":[62],"determined":[64],"by":[65,112],"number":[67],"organs":[69],"failing":[70,99,155],"(sequential":[71],"assessment":[74],"[SOFA]":[75],"score),":[76],"presence":[78],"infection,":[80],"degree":[83],"liver":[85,110,148,190],"dysfunction":[86],"(Child-Turcotte-Pugh":[87],"Model":[89],"for":[90],"End-Stage":[91],"Liver":[92,157],"Disease":[93],"scores).":[94],"The":[95],"most":[96],"common":[97],"kidney;":[102],"sepsis":[103],"further":[107,145],"function":[111],"compromise":[113],"microcirculation.":[116],"Care":[117],"these":[119,183,202],"critically":[120],"ill":[121],"impending":[124],"requires":[128],"team":[130],"approach":[131],"expertise":[133],"both":[135],"hepatology":[136],"critical":[138],"care.":[139],"Treatment":[140,171],"aimed":[142],"at":[143],"preventing":[144],"function,":[149],"reversing":[150],"precipitating":[151],"factors,":[152],"supporting":[154],"organs.":[156],"transplantation":[158],"required":[160],"selected":[162],"improve":[165],"survival":[166,199],"quality":[168],"life.":[170],"futile":[173],"some":[175],"patients,":[176],"but":[177],"it":[178],"difficult":[180],"identify":[182],"priori.":[186],"Artificial":[187],"bioartificial":[189],"support":[191],"systems":[192],"thus":[194],"far":[195],"not":[196],"demonstrated":[197],"significant":[198],"benefit":[200],"patients.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":26},{"year":2017,"cited_by_count":24},{"year":2016,"cited_by_count":24},{"year":2015,"cited_by_count":31},{"year":2014,"cited_by_count":31},{"year":2013,"cited_by_count":17},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}