{"id":"https://openalex.org/W2066043681","doi":"https://doi.org/10.1038/196683a0","title":"Tissue Eosinophilia in Hypersensitivity Reactions as revealed by the Human Skin Window","display_name":"Tissue Eosinophilia in Hypersensitivity Reactions as revealed by the Human Skin Window","publication_year":1962,"publication_date":"1962-11-01","ids":{"openalex":"https://openalex.org/W2066043681","doi":"https://doi.org/10.1038/196683a0","mag":"2066043681"},"language":"en","primary_location":{"id":"doi:10.1038/196683a0","doi":"https://doi.org/10.1038/196683a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/196683a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040070300","display_name":"David Eidinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D. EIDINGER","raw_affiliation_strings":["Department of Immunochemistry and Allergy, Royal Victoria Hospital, Montreal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunochemistry and Allergy, Royal Victoria Hospital, Montreal","institution_ids":["https://openalex.org/I4210088756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077866122","display_name":"Manfred Raff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. RAFF","raw_affiliation_strings":["Department of Immunochemistry and Allergy, Royal Victoria Hospital, Montreal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunochemistry and Allergy, Royal Victoria Hospital, Montreal","institution_ids":["https://openalex.org/I4210088756"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113771278","display_name":"Bram Rose","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"B. ROSE","raw_affiliation_strings":["Department of Immunochemistry and Allergy, Royal Victoria Hospital, Montreal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunochemistry and Allergy, Royal Victoria Hospital, Montreal","institution_ids":["https://openalex.org/I4210088756"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210088756"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":10.6364,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.98631699,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"196","issue":"4855","first_page":"683","last_page":"684"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":0.44190001487731934,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":0.44190001487731934,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.29589998722076416,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.18199999630451202,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eosinophilia","display_name":"eosinophilia","score":0.7549999952316284},{"id":"https://openalex.org/keywords/hypersensitivity","display_name":"hypersensitivity","score":0.8220000267028809},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.9330000281333923},{"id":"https://openalex.org/keywords/eosinophil-function","display_name":"eosinophil function","score":0.75},{"id":"https://openalex.org/keywords/histamine","display_name":"histamine","score":0.8420000076293945},{"id":"https://openalex.org/keywords/antihistaminic-activity","display_name":"antihistaminic activity","score":0.828000009059906},{"id":"https://openalex.org/keywords/eosinophil-granules","display_name":"eosinophil granules","score":0.8370000123977661},{"id":"https://openalex.org/keywords/charcot-leyden-crystals","display_name":"Charcot-Leyden crystals","score":0.9150000214576721}],"concepts":[{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.9043091535568237},{"id":"https://openalex.org/C2777129736","wikidata":"https://www.wikidata.org/wiki/Q505142","display_name":"Eosinophilia","level":2,"score":0.6996238827705383},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.62126225233078},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.615627110004425},{"id":"https://openalex.org/C60483475","wikidata":"https://www.wikidata.org/wiki/Q1886099","display_name":"Major basic protein","level":4,"score":0.5421413779258728},{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.5148362517356873},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4796588718891144},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4102446436882019},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37318024039268494},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.359591007232666},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/196683a0","doi":"https://doi.org/10.1038/196683a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/196683a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W613360632","https://openalex.org/W1576010110","https://openalex.org/W1775562771","https://openalex.org/W1965637485","https://openalex.org/W1965903950","https://openalex.org/W1987445668","https://openalex.org/W1987891133","https://openalex.org/W2003309308","https://openalex.org/W2027472039","https://openalex.org/W2056029981","https://openalex.org/W2060380614","https://openalex.org/W2159024009","https://openalex.org/W2270786816","https://openalex.org/W2320326727","https://openalex.org/W4322152681"],"related_works":["https://openalex.org/W7113255573","https://openalex.org/W7111969883","https://openalex.org/W1985186436","https://openalex.org/W1800986074","https://openalex.org/W2086775550","https://openalex.org/W1989249086","https://openalex.org/W4249625894","https://openalex.org/W1996693481","https://openalex.org/W2139147598","https://openalex.org/W2135474267"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}