{"id":"https://openalex.org/W2065634643","doi":"https://doi.org/10.1016/s1001-9294(10)60024-7","title":"Antagomir Dependent MicroRNA-205 Reduction Enhances Adhesion Ability of Human Corneal Epithelial Keratinocytes","display_name":"Antagomir Dependent MicroRNA-205 Reduction Enhances Adhesion Ability of Human Corneal Epithelial Keratinocytes","publication_year":2010,"publication_date":"2010-06-01","ids":{"openalex":"https://openalex.org/W2065634643","doi":"https://doi.org/10.1016/s1001-9294(10)60024-7","mag":"2065634643","pmid":"https://pubmed.ncbi.nlm.nih.gov/20598226"},"language":"en","primary_location":{"id":"doi:10.1016/s1001-9294(10)60024-7","doi":"https://doi.org/10.1016/s1001-9294(10)60024-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1001-9294(10)60024-7","pdf_url":"http://cmsj.cams.cn/CN/article/downloadArticleFile.do?attachType=PDF&id=1","source":{"id":"https://openalex.org/S4306541546","display_name":"Chinese Medical Sciences Journal","issn_l":"1001-9294","issn":["1001-9294","2352-4014"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","medline","norway-1","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Medical Sciences Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://cmsj.cams.cn/CN/article/downloadArticleFile.do?attachType=PDF&id=1","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100361716","display_name":"Jun Li","orcid":"https://orcid.org/0000-0001-9121-6162","observed_orcids":["https://orcid.org/0000-0001-9121-6162"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Li","raw_affiliation_strings":["Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academyof Medical Sciences & Peking Union Medical College, Beijing 100005, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academyof Medical Sciences & Peking Union Medical College, Beijing 100005, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hua Bai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210124286","display_name":"The Military General Hospital of Beijing PLA","ror":"https://ror.org/0259e4473","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124286"]},{"id":"https://openalex.org/I4210160531","display_name":"Chinese People's Liberation Army","ror":"https://ror.org/05tf9r976","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hua Bai","raw_affiliation_strings":["a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I200296433","https://openalex.org/I4210124286","https://openalex.org/I4391767653"]},{"raw_affiliation_string":"Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China","institution_ids":["https://openalex.org/I4210124286","https://openalex.org/I4210160531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083010305","display_name":"Yong Zhu","orcid":"https://orcid.org/0000-0003-0701-343X","observed_orcids":["https://orcid.org/0000-0003-0701-343X"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210124286","display_name":"The Military General Hospital of Beijing PLA","ror":"https://ror.org/0259e4473","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124286"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yong Zhu","raw_affiliation_strings":["a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I200296433","https://openalex.org/I4210124286","https://openalex.org/I4391767653"]},{"raw_affiliation_string":"Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100381765","display_name":"Xiaoyan Wang","orcid":"https://orcid.org/0000-0001-5568-2131","observed_orcids":["https://orcid.org/0000-0001-5568-2131"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210124286","display_name":"The Military General Hospital of Beijing PLA","ror":"https://ror.org/0259e4473","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124286"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Xiao-yan Wang","raw_affiliation_strings":["a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I200296433","https://openalex.org/I4210124286","https://openalex.org/I4391767653"]},{"raw_affiliation_string":"Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101981092","display_name":"Fang Wang","orcid":"https://orcid.org/0000-0002-7203-9970","observed_orcids":["https://orcid.org/0000-0002-7203-9970"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210124286","display_name":"The Military General Hospital of Beijing PLA","ror":"https://ror.org/0259e4473","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124286"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Fang Wang","raw_affiliation_strings":["a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I200296433","https://openalex.org/I4210124286","https://openalex.org/I4391767653"]},{"raw_affiliation_string":"Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111746247","display_name":"Jun-Wu Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210124286","display_name":"The Military General Hospital of Beijing PLA","ror":"https://ror.org/0259e4473","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124286"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Jun-wu Zhang","raw_affiliation_strings":["a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"a Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China\nb Department of Cardiology, Chongqing First-aid Medical Center, Chongqing 400014, China\nc Department of Ophthalmology, The Military General Hospital of Beijing PLA, Beijing 100700, China\nd Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I200296433","https://openalex.org/I4210124286","https://openalex.org/I4391767653"]},{"raw_affiliation_string":"Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091815534","display_name":"Robert M. Lavker","orcid":"https://orcid.org/0000-0003-2570-9537","observed_orcids":["https://orcid.org/0000-0003-2570-9537"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Robert M. Lavker","raw_affiliation_strings":["Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","Institute of Basic Medical Sciences , Chinese Academy of Medical Sciences Grant (2009RC03) and National Institutes of Health Grants (EY017536 , EY019463) "],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago 60611, USA","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Institute of Basic Medical Sciences , Chinese Academy of Medical Sciences Grant (2009RC03) and National Institutes of Health Grants (EY017536 , EY019463) ","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034416053","display_name":"Jia Yu","orcid":"https://orcid.org/0000-0003-3499-5133","observed_orcids":["https://orcid.org/0000-0003-3499-5133"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Yu","raw_affiliation_strings":["Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2925,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.57439682,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"25","issue":"2","first_page":"65","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.05609999969601631,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna-205","display_name":"microRNA-205","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antagomir","display_name":"antagomir","score":0.9589999914169312},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.9980000257492065},{"id":"https://openalex.org/keywords/focal-adhesion-kinase","display_name":"focal adhesion kinase","score":0.9800000190734863},{"id":"https://openalex.org/keywords/paxillin","display_name":"paxillin","score":0.968999981880188},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cell-motility","display_name":"cell motility","score":0.906000018119812},{"id":"https://openalex.org/keywords/microrna-inhibition","display_name":"microRNA inhibition","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C151166631","wikidata":"https://www.wikidata.org/wiki/Q904514","display_name":"Focal adhesion","level":3,"score":0.8596165180206299},{"id":"https://openalex.org/C116581196","wikidata":"https://www.wikidata.org/wiki/Q14906591","display_name":"Paxillin","level":4,"score":0.8104585409164429},{"id":"https://openalex.org/C2779368916","wikidata":"https://www.wikidata.org/wiki/Q425022","display_name":"Antagomir","level":4,"score":0.6243411302566528},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5854479074478149},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.5508208870887756},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.532912015914917},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.4888145625591278},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.46325287222862244},{"id":"https://openalex.org/C58207958","wikidata":"https://www.wikidata.org/wiki/Q33596","display_name":"Motility","level":2,"score":0.44822224974632263},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35833531618118286},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3222261965274811},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24788856506347656},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.20119699835777283},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12048375606536865},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.11669489741325378},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015345","descriptor_name":"Oligonucleotide Probes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D019573","descriptor_name":"Epithelium, Corneal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1001-9294(10)60024-7","doi":"https://doi.org/10.1016/s1001-9294(10)60024-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1001-9294(10)60024-7","pdf_url":"http://cmsj.cams.cn/CN/article/downloadArticleFile.do?attachType=PDF&id=1","source":{"id":"https://openalex.org/S4306541546","display_name":"Chinese Medical Sciences Journal","issn_l":"1001-9294","issn":["1001-9294","2352-4014"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","medline","norway-1","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Medical Sciences Journal","raw_type":"journal-article"},{"id":"pmid:20598226","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20598226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s1001-9294(10)60024-7","doi":"https://doi.org/10.1016/s1001-9294(10)60024-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1001-9294(10)60024-7","pdf_url":"http://cmsj.cams.cn/CN/article/downloadArticleFile.do?attachType=PDF&id=1","source":{"id":"https://openalex.org/S4306541546","display_name":"Chinese Medical Sciences Journal","issn_l":"1001-9294","issn":["1001-9294","2352-4014"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","medline","norway-1","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Medical Sciences Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2699526885","display_name":"MicroRNAs and Corneal Epithelial Stem Cells","funder_award_id":"R21EY017536","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8377137381","display_name":"The Role of MicroRNAs in Corneal Epithelial Homeostasis","funder_award_id":"R01EY019463","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G9001303306","display_name":null,"funder_award_id":"2009RC03","funder_id":"https://openalex.org/F4320323137","funder_display_name":"Chinese Academy of Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320323137","display_name":"Chinese Academy of Medical Sciences","ror":"https://ror.org/03cve4549"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2065634643.pdf","grobid_xml":"https://content.openalex.org/works/W2065634643.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1836265445","https://openalex.org/W1965371218","https://openalex.org/W1973144992","https://openalex.org/W1976324983","https://openalex.org/W1978944350","https://openalex.org/W1983453097","https://openalex.org/W1988224683","https://openalex.org/W2006066303","https://openalex.org/W2007353065","https://openalex.org/W2010784970","https://openalex.org/W2017714432","https://openalex.org/W2023153759","https://openalex.org/W2044880285","https://openalex.org/W2047529648","https://openalex.org/W2063220206","https://openalex.org/W2070732456","https://openalex.org/W2077582389","https://openalex.org/W2084764067","https://openalex.org/W2087016227","https://openalex.org/W2099616303","https://openalex.org/W2102246255","https://openalex.org/W2105809801","https://openalex.org/W2106532933","https://openalex.org/W2110088869","https://openalex.org/W2112006376","https://openalex.org/W2120785986","https://openalex.org/W2135106752","https://openalex.org/W2135836598","https://openalex.org/W2145822440","https://openalex.org/W2149146453","https://openalex.org/W2150597604","https://openalex.org/W2160922815","https://openalex.org/W2171836441","https://openalex.org/W4237473415"],"related_works":["https://openalex.org/W2135666474","https://openalex.org/W2374987401","https://openalex.org/W1991371383","https://openalex.org/W2387425721","https://openalex.org/W3009474165","https://openalex.org/W2074251746","https://openalex.org/W2068495384","https://openalex.org/W1430980257","https://openalex.org/W2047462905","https://openalex.org/W2106532933"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"the":[3,55,75,87,110],"effect":[4,130],"of":[5,13,38,57,77,89,98,107,112],"microRNA-205":[6,32,90,108,127],"reduction":[7],"by":[8,44],"antagomirs":[9],"on":[10,131],"adhesion":[11,36,46,63,96],"ability":[12,37,97],"normal":[14],"human":[15],"corneal":[16],"epithelial":[17],"keratinocytes":[18],"(NHCEKs).":[19],"METHODS:":[20],"Antagomir-205,":[21],"complementary":[22],"and":[23,49,66,93,115,118],"inhibitory":[24],"to":[25,29,53,73],"microRNA-205,":[26],"was":[27,41,71],"used":[28],"suppress":[30],"endogenous":[31],"in":[33,80,91,134],"NHCEKs.":[34,82,135],"The":[35],"treated":[39],"NHCEKs":[40,92,99],"then":[42],"assessed":[43],"cell":[45,132],"assay.":[47],"Immunoblot":[48],"immunohistochemistry":[50],"were":[51],"conducted":[52],"determine":[54],"level":[56,76,88],"two":[58],"focal":[59,62],"adhesion-related":[60],"proteins,":[61],"kinase":[64],"(FAK)":[65],"paxillin":[67],"(Pax).":[68],"Phalloidin":[69],"staining":[70],"performed":[72],"measure":[74],"filamentous":[78,120],"actin":[79],"antagomir-treated":[81],"RESULTS:":[83],"Antagomir-205":[84],"markedly":[85],"reduced":[86],"significantly":[94],"enhanced":[95],"(P<0.01).":[100],"Further":[101],"protein":[102],"analysis":[103],"validated":[104],"that":[105,126],"inhibition":[106],"increased":[109],"number":[111],"phosphorylated":[113,116],"FAK":[114],"Pax,":[117],"decreased":[119],"actin.":[121],"CONCLUSION:":[122],"Our":[123],"findings":[124],"suggest":[125],"has":[128],"down-regulating":[129],"motility":[133]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}