{"id":"https://openalex.org/W2063926261","doi":"https://doi.org/10.4172/jpb.s1000237","title":"Novel Carbohydrate Cluster Microarrays Technology for Profiling Glycan Functions","display_name":"Novel Carbohydrate Cluster Microarrays Technology for Profiling Glycan Functions","publication_year":2009,"publication_date":"2009-07-01","ids":{"openalex":"https://openalex.org/W2063926261","doi":"https://doi.org/10.4172/jpb.s1000237","mag":"2063926261"},"language":"en","primary_location":{"id":"doi:10.4172/jpb.s1000237","doi":"https://doi.org/10.4172/jpb.s1000237","is_oa":false,"landing_page_url":"http://doi.org/10.4172/jpb.s1000237","pdf_url":null,"source":{"id":"https://openalex.org/S124242604","display_name":"Journal of Proteomics & Bioinformatics","issn_l":"0974-276X","issn":["0974-276X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Proteomics & Bioinformatics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111695647","display_name":"Xichun Zhou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Dr. Xichun Zhou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5111695647"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15497721,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"S3","issue":"01","first_page":"004","last_page":"004"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.5228999853134155,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.5228999853134155,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.33500000834465027,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.10239999741315842,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycan-profiling","display_name":"glycan profiling","score":0.6359999775886536},{"id":"https://openalex.org/keywords/glycomics","display_name":"glycomics","score":0.6299999952316284},{"id":"https://openalex.org/keywords/influenza-hemagglutinin","display_name":"influenza hemagglutinin","score":0.8849999904632568},{"id":"https://openalex.org/keywords/biotoxin-detection","display_name":"biotoxin detection","score":0.9900000095367432},{"id":"https://openalex.org/keywords/bioimaging","display_name":"bioimaging","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.7788809537887573},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.7350153923034668},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.635013997554779},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.6037609577178955},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.4602436423301697},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38189539313316345},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.32358527183532715},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31585079431533813},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.131352961063385},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09599095582962036},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.06042364239692688},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.05345234274864197},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4172/jpb.s1000237","doi":"https://doi.org/10.4172/jpb.s1000237","is_oa":false,"landing_page_url":"http://doi.org/10.4172/jpb.s1000237","pdf_url":null,"source":{"id":"https://openalex.org/S124242604","display_name":"Journal of Proteomics & Bioinformatics","issn_l":"0974-276X","issn":["0974-276X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Proteomics & Bioinformatics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2006463471","https://openalex.org/W14841305","https://openalex.org/W2148174143","https://openalex.org/W4211102761","https://openalex.org/W2101908398","https://openalex.org/W1492054572","https://openalex.org/W2163455726","https://openalex.org/W47973316","https://openalex.org/W2115496163","https://openalex.org/W2081646165"],"abstract_inverted_index":{"First,":[0],"we":[1],"introduce":[2,167],"a":[3,20,136],"novel,":[4],"ready-to-use":[5],"bioarray":[6,63,96],"platform":[7,64,97],"and":[8,37,53,104,117,122,147,161,177,191],"methodology":[9],"for":[10,40,60,85,112,140,152,188],"construction":[11,148],"of":[12,43,48,55,71,114,120,135,138,144,149,155,159,174,185],"sensitive":[13,142],"carbohydrate":[14,72,82],"cluster":[15,105],"microarrays.":[16],"This":[17],"technology":[18],"utilizes":[19],"3-dimensional":[21],"(3-D)":[22],"poly(amidoamine)":[23],"starburst":[24],"dendrimer":[25],"monolayer":[26],"assembled":[27],"on":[28,171],"glass":[29],"surface,":[30],"which":[31],"is":[32,74,88,131],"functionalized":[33],"with":[34],"terminal":[35],"aminooxy":[36],"hydrazide":[38],"groups":[39],"site-specific":[41],"coupling":[42,73],"carbohydrates.":[44],"A":[45],"wide":[46],"range":[47],"saccharides,":[49],"including":[50],"monosaccharides,":[51],"oligosaccharides":[52],"polysaccharides":[54],"diverse":[56],"structures,":[57],"are":[58],"applicable":[59],"the":[61,115,156,172,183,186],"3-D":[62],"without":[65],"prior":[66],"chemical":[67],"derivatization.":[68],"The":[69,81],"process":[70],"effectively":[75],"accelerated":[76],"by":[77,133],"microwave":[78],"radiation":[79],"energy.":[80],"concentration":[83],"required":[84],"microarray":[86],"fabrication":[87],"substantially":[89],"reduced":[90],"using":[91],"this":[92,95],"technology.":[93],"Importantly,":[94],"presents":[98],"sugar":[99,150],"chains":[100],"in":[101,128],"defined":[102],"orientation":[103],"configurations.":[106],"It":[107],"is,":[108],"thus,":[109],"uniquely":[110],"useful":[111],"exploration":[113],"structural":[116],"conformational":[118],"diversities":[119],"glyco-epitope":[121],"their":[123],"functional":[124],"properties.":[125],"Its":[126],"potential":[127],"glycomics":[129],"application":[130,184],"demonstrated":[132],"chip-display":[134],"panel":[137],"glyco-epitopes":[139],"highly":[141],"detection":[143,154,190],"carbohydrate-binding":[145],"proteins":[146],"microarrays":[151],"differential":[153],"Influenza":[157],"hemagglutinins":[158],"H3N1":[160],"H5N1.":[162],"We":[163],"will":[164],"also":[165],"briefly":[166],"our":[168],"recently":[169],"research":[170],"development":[173],"Au":[175],"glyconanoparticles":[176,187],"fluorescent":[178],"glycolnanoparticles,":[179],"as":[180,182],"well":[181],"biotoxin":[189],"bio-imaging.":[192]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}