{"id":"https://openalex.org/W2063377705","doi":"https://doi.org/10.1016/s0039-6060(03)00294-0","title":"The role of poxviruses in tumor immunotherapy","display_name":"The role of poxviruses in tumor immunotherapy","publication_year":2003,"publication_date":"2003-11-01","ids":{"openalex":"https://openalex.org/W2063377705","doi":"https://doi.org/10.1016/s0039-6060(03)00294-0","mag":"2063377705","pmid":"https://pubmed.ncbi.nlm.nih.gov/14639347"},"language":"en","primary_location":{"id":"doi:10.1016/s0039-6060(03)00294-0","doi":"https://doi.org/10.1016/s0039-6060(03)00294-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0039-6060(03)00294-0","pdf_url":null,"source":{"id":"https://openalex.org/S4210173306","display_name":"Surgery","issn_l":"0039-6060","issn":["0039-6060","1532-7361"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090739964","display_name":"Howard L. Kaufman","orcid":"https://orcid.org/0000-0003-1131-004X","observed_orcids":["https://orcid.org/0000-0003-1131-004X","https://orcid.org/0000-0003-3538-4166"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Howard L Kaufman","raw_affiliation_strings":["Department of Surgery and Pathology, College of Physicians & Surgeons, Columbia University, 630 W 168th Street, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery and Pathology, College of Physicians & Surgeons, Columbia University, 630 W 168th Street, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090739964"],"corresponding_institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":0.2162,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.53435736,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"134","issue":"5","first_page":"731","last_page":"737"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.926800012588501,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.926800012588501,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11767","display_name":"Poxvirus research and outbreaks","score":0.041999999433755875,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/poxvirus","display_name":"poxvirus","score":0.968999981880188},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.8659999966621399},{"id":"https://openalex.org/keywords/vaccinia-virus","display_name":"vaccinia virus","score":0.9269999861717224},{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.6729999780654907},{"id":"https://openalex.org/keywords/tumor-antigens","display_name":"tumor antigens","score":0.7200000286102295},{"id":"https://openalex.org/keywords/smallpox-eradication","display_name":"smallpox eradication","score":0.7689999938011169},{"id":"https://openalex.org/keywords/expression-vectors","display_name":"expression vectors","score":0.7229999899864197},{"id":"https://openalex.org/keywords/advanced-cancer","display_name":"advanced cancer","score":0.4659999907016754},{"id":"https://openalex.org/keywords/vaccine-safety","display_name":"vaccine safety","score":0.40299999713897705},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C2778417375","wikidata":"https://www.wikidata.org/wiki/Q12214","display_name":"Smallpox","level":3,"score":0.8565927743911743},{"id":"https://openalex.org/C2781356689","wikidata":"https://www.wikidata.org/wiki/Q1986297","display_name":"Vaccinia","level":4,"score":0.8050934076309204},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7782348394393921},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6153233051300049},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5737457871437073},{"id":"https://openalex.org/C2779272165","wikidata":"https://www.wikidata.org/wiki/Q1037810","display_name":"Smallpox vaccine","level":5,"score":0.5679274797439575},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5164199471473694},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5160079002380371},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5116344094276428},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5035440325737},{"id":"https://openalex.org/C2777760223","wikidata":"https://www.wikidata.org/wiki/Q6889412","display_name":"Modified vaccinia Ankara","level":5,"score":0.5030583739280701},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.47262072563171387},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4661575257778168},{"id":"https://openalex.org/C2779827044","wikidata":"https://www.wikidata.org/wiki/Q948421","display_name":"Poxviridae","level":5,"score":0.45303308963775635},{"id":"https://openalex.org/C2780674031","wikidata":"https://www.wikidata.org/wiki/Q2012719","display_name":"Cancer immunotherapy","level":4,"score":0.4214625358581543},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16319963335990906},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.14135757088661194},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08372533321380615},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08147478103637695},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011212","descriptor_name":"Poxviridae","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011212","descriptor_name":"Poxviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014614","descriptor_name":"Vaccines, Synthetic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0039-6060(03)00294-0","doi":"https://doi.org/10.1016/s0039-6060(03)00294-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0039-6060(03)00294-0","pdf_url":null,"source":{"id":"https://openalex.org/S4210173306","display_name":"Surgery","issn_l":"0039-6060","issn":["0039-6060","1532-7361"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"journal-article"},{"id":"pmid:14639347","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14639347","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7599999904632568}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1093478081","display_name":"ANTIGEN PRESENTATION BY CEA DIRECTED TUMOR VACCINES","funder_award_id":"K08CA079881","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6649607671","display_name":"ENHANCING TUMOR VACCINES WITH CO-STIMULATORY MOLECULES","funder_award_id":"R01CA093696","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1623078040","https://openalex.org/W1960833366","https://openalex.org/W1986523328","https://openalex.org/W1989654999","https://openalex.org/W1990507442","https://openalex.org/W2067039219","https://openalex.org/W2136751371","https://openalex.org/W2151174052","https://openalex.org/W2156467383","https://openalex.org/W2170629861","https://openalex.org/W6636559269"],"related_works":["https://openalex.org/W2406584306","https://openalex.org/W1981099638","https://openalex.org/W2215284278","https://openalex.org/W1975015202","https://openalex.org/W2601817904","https://openalex.org/W4246044966","https://openalex.org/W2003272327","https://openalex.org/W2098241744","https://openalex.org/W2139083904","https://openalex.org/W2483319721"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}