{"id":"https://openalex.org/W2063312972","doi":"https://doi.org/10.1063/1.1148163","title":"Design and performance of an integrated fluorescence, polarized fluorescence, and Brewster angle microscope/Langmuir trough assembly for the study of lung surfactant monolayers","display_name":"Design and performance of an integrated fluorescence, polarized fluorescence, and Brewster angle microscope/Langmuir trough assembly for the study of lung surfactant monolayers","publication_year":1997,"publication_date":"1997-06-01","ids":{"openalex":"https://openalex.org/W2063312972","doi":"https://doi.org/10.1063/1.1148163","mag":"2063312972"},"language":"en","primary_location":{"id":"doi:10.1063/1.1148163","doi":"https://doi.org/10.1063/1.1148163","is_oa":false,"landing_page_url":"https://doi.org/10.1063/1.1148163","pdf_url":null,"source":{"id":"https://openalex.org/S31010182","display_name":"Review of Scientific Instruments","issn_l":"0034-6748","issn":["0034-6748","1089-7623","1527-2400"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Review of Scientific Instruments","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015702014","display_name":"Michael M. Lipp","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael M. Lipp","raw_affiliation_strings":["Department of Chemical Engineering, University of California, Santa Barbara, California 93106"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, University of California, Santa Barbara, California 93106","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032214572","display_name":"Ka Yee C. Lee","orcid":"https://orcid.org/0000-0003-0895-336X","observed_orcids":["https://orcid.org/0000-0003-0895-336X"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ka Yee C. Lee","raw_affiliation_strings":["Department of Chemical Engineering, University of California, Santa Barbara, California 93106"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, University of California, Santa Barbara, California 93106","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029251110","display_name":"Joseph A. Zasadzinski","orcid":"https://orcid.org/0000-0001-5663-6989","observed_orcids":["https://orcid.org/0000-0001-5663-6989"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph A. Zasadzinski","raw_affiliation_strings":["Department of Chemical Engineering, University of California, Santa Barbara, California 93106"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, University of California, Santa Barbara, California 93106","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087075708","display_name":"Alan J. Waring","orcid":"https://orcid.org/0000-0002-0151-2695","observed_orcids":["https://orcid.org/0000-0002-0151-2695"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan J. Waring","raw_affiliation_strings":["Department of Pediatrics, King/Drew University Medical Center and Perinatal Laboratories, Harbor-UCLA School of Medicine, Los Angeles, California 90059"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, King/Drew University Medical Center and Perinatal Laboratories, Harbor-UCLA School of Medicine, Los Angeles, California 90059","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5954,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.62384494,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"68","issue":"6","first_page":"2574","last_page":"2582"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.49320000410079956,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.49320000410079956,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.2515000104904175,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.10909999907016754,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-surfactant","display_name":"pulmonary surfactant","score":0.9419999718666077},{"id":"https://openalex.org/keywords/langmuir-monolayers","display_name":"Langmuir monolayers","score":0.8939999938011169},{"id":"https://openalex.org/keywords/brewster-angle-microscopy","display_name":"Brewster angle microscopy","score":0.9660000205039978},{"id":"https://openalex.org/keywords/fluorescence-microscopy","display_name":"fluorescence microscopy","score":0.7950000166893005},{"id":"https://openalex.org/keywords/mixed-lipid-monolayers","display_name":"mixed lipid monolayers","score":0.859000027179718},{"id":"https://openalex.org/keywords/anionic-lipids","display_name":"anionic lipids","score":0.7210000157356262},{"id":"https://openalex.org/keywords/unsaturated-lipids","display_name":"unsaturated lipids","score":0.9800000190734863},{"id":"https://openalex.org/keywords/protein-lipid-interactions","display_name":"protein-lipid interactions","score":0.824999988079071}],"concepts":[{"id":"https://openalex.org/C35068176","wikidata":"https://www.wikidata.org/wiki/Q662790","display_name":"Brewster's angle","level":3,"score":0.9650252461433411},{"id":"https://openalex.org/C7070889","wikidata":"https://www.wikidata.org/wiki/Q902488","display_name":"Monolayer","level":2,"score":0.9537508487701416},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.6956501007080078},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.6561280488967896},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.5844706296920776},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.5769603252410889},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5739883780479431},{"id":"https://openalex.org/C115958267","wikidata":"https://www.wikidata.org/wiki/Q464196","display_name":"Langmuir","level":3,"score":0.5320345759391785},{"id":"https://openalex.org/C67649825","wikidata":"https://www.wikidata.org/wiki/Q196538","display_name":"Microscope","level":2,"score":0.4861554801464081},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.399310827255249},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3795245885848999},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32477349042892456},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3209555745124817},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.31799912452697754},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.16925376653671265},{"id":"https://openalex.org/C2780048723","wikidata":"https://www.wikidata.org/wiki/Q4962736","display_name":"Brewster","level":2,"score":0.11741074919700623},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08983176946640015},{"id":"https://openalex.org/C150394285","wikidata":"https://www.wikidata.org/wiki/Q180254","display_name":"Adsorption","level":2,"score":0.08535310626029968},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08483591675758362},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07806777954101562},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.057119667530059814}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1063/1.1148163","doi":"https://doi.org/10.1063/1.1148163","is_oa":false,"landing_page_url":"https://doi.org/10.1063/1.1148163","pdf_url":null,"source":{"id":"https://openalex.org/S31010182","display_name":"Review of Scientific Instruments","issn_l":"0034-6748","issn":["0034-6748","1089-7623","1527-2400"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Review of Scientific Instruments","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W107992251","https://openalex.org/W599063292","https://openalex.org/W1546413526","https://openalex.org/W1972590384","https://openalex.org/W1976027289","https://openalex.org/W1989320161","https://openalex.org/W1989367423","https://openalex.org/W2012222136","https://openalex.org/W2019278648","https://openalex.org/W2025457908","https://openalex.org/W2029522896","https://openalex.org/W2030425487","https://openalex.org/W2030549092","https://openalex.org/W2034624273","https://openalex.org/W2043563857","https://openalex.org/W2067132840","https://openalex.org/W2067922071","https://openalex.org/W2091742541","https://openalex.org/W2118587471","https://openalex.org/W2123201184","https://openalex.org/W2130081721","https://openalex.org/W2135250620","https://openalex.org/W2135761356","https://openalex.org/W2266770229"],"related_works":["https://openalex.org/W2056451875","https://openalex.org/W1635701300","https://openalex.org/W2041562933","https://openalex.org/W2618472268","https://openalex.org/W4292772985","https://openalex.org/W147525449","https://openalex.org/W2088919342","https://openalex.org/W3036851690","https://openalex.org/W2068839830","https://openalex.org/W2035731913"],"abstract_inverted_index":{"We":[0],"describe":[1],"an":[2],"integrated":[3],"fluorescence,":[4,6],"polarized":[5],"and":[7,26,48,61,94,114,120,129],"Brewster":[8,49],"angle":[9,50],"microscope/Langmuir":[10],"trough":[11],"assembly.":[12],"This":[13],"apparatus":[14,39],"was":[15],"specifically":[16],"designed":[17],"for":[18,30],"the":[19,31,46,73,76,86,112,133,136],"study":[20,32,85],"of":[21,33,56,65,75,78,88,108,111,118,139],"lung":[22],"surfactant":[23],"(LS)":[24],"monolayers,":[25,93],"is":[27],"well":[28],"suited":[29],"other":[34],"lipid/protein":[35],"monolayer":[36],"systems.":[37],"The":[38,63],"can":[40],"be":[41],"operated":[42],"simultaneously":[43],"in":[44],"both":[45],"fluorescence":[47],"modes":[51],"under":[52],"a":[53],"wide":[54],"range":[55],"conditions,":[57],"including":[58],"physiological":[59],"subphases":[60],"temperatures.":[62],"combination":[64],"information":[66],"obtained":[67],"from":[68],"these":[69,130],"microscopy":[70],"techniques":[71],"facilitates":[72],"identification":[74],"composition":[77],"coexisting":[79],"phases,":[80],"allows":[81],"us":[82],"to":[83,99,135],"systematically":[84],"effects":[87],"specific":[89],"proteins":[90,128],"on":[91],"lipid":[92,116],"eliminates":[95],"possible":[96],"artifacts":[97],"inherent":[98],"fluorescence.":[100],"To":[101],"demonstrate":[102],"this":[103],"system":[104],"we":[105],"present":[106],"images":[107],"mixed":[109],"monolayers":[110],"anionic":[113],"unsaturated":[115],"components":[117],"LS":[119,127,140],"show":[121],"that":[122],"synergistic":[123],"interactions":[124],"between":[125],"certain":[126],"lipids":[131],"hold":[132],"key":[134],"proper":[137],"functioning":[138],"monolayers.":[141]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2016-06-24T00:00:00"}