{"id":"https://openalex.org/W206279403","doi":"https://doi.org/10.1016/b978-012253840-7/50007-9","title":"EXPRESSION IN THE METHYLOTROPHIC YEAST Pichia pastoris","display_name":"EXPRESSION IN THE METHYLOTROPHIC YEAST Pichia pastoris","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W206279403","doi":"https://doi.org/10.1016/b978-012253840-7/50007-9","mag":"206279403"},"language":"en","primary_location":{"id":"doi:10.1016/b978-012253840-7/50007-9","doi":"https://doi.org/10.1016/b978-012253840-7/50007-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012253840-7/50007-9","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene Expression Systems","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4252257957","display_name":"Gene Expression Systems"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110525140","display_name":"James M. Cregg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"James M. Cregg","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and Technology, Portland, Oregon 97291"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and Technology, Portland, Oregon 97291","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5110525140"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.7404,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.93627176,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"157","last_page":"191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12668","display_name":"Yeasts and Rust Fungi Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/komagataella-phaffii","display_name":"Pichia pastoris","score":0.9959999918937683},{"id":"https://openalex.org/keywords/heterologous-expression","display_name":"heterologous expression","score":0.8790000081062317},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.7720000147819519},{"id":"https://openalex.org/keywords/methylotrophic-yeast","display_name":"methylotrophic yeast","score":0.6119999885559082},{"id":"https://openalex.org/keywords/protein-secretion","display_name":"protein secretion","score":0.6110000014305115},{"id":"https://openalex.org/keywords/yeast-proteases","display_name":"yeast proteases","score":0.8330000042915344},{"id":"https://openalex.org/keywords/protein-degradation","display_name":"protein degradation","score":0.718999981880188}],"concepts":[{"id":"https://openalex.org/C2781372317","wikidata":"https://www.wikidata.org/wiki/Q148697","display_name":"Pichia pastoris","level":4,"score":0.9869003295898438},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.5735825300216675},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5624712705612183},{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.530403733253479},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5273481607437134},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.5143688917160034},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.5102410316467285},{"id":"https://openalex.org/C2779703480","wikidata":"https://www.wikidata.org/wiki/Q125153","display_name":"Pichia","level":5,"score":0.47470465302467346},{"id":"https://openalex.org/C19843653","wikidata":"https://www.wikidata.org/wiki/Q213907","display_name":"Model organism","level":3,"score":0.4499621093273163},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4421297609806061},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.4400758445262909},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.4196927845478058},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3027760982513428},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.246250718832016},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2003621757030487},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15936043858528137},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15102314949035645},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.07023811340332031},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0609300434589386},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05849704146385193},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-012253840-7/50007-9","doi":"https://doi.org/10.1016/b978-012253840-7/50007-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012253840-7/50007-9","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene Expression Systems","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":106,"referenced_works":["https://openalex.org/W100624870","https://openalex.org/W341961073","https://openalex.org/W373609572","https://openalex.org/W1267248164","https://openalex.org/W1560734798","https://openalex.org/W1561515054","https://openalex.org/W1595979491","https://openalex.org/W1754074313","https://openalex.org/W1788098526","https://openalex.org/W1879503128","https://openalex.org/W1890235904","https://openalex.org/W1938341712","https://openalex.org/W1963627858","https://openalex.org/W1964566479","https://openalex.org/W1965020882","https://openalex.org/W1966164969","https://openalex.org/W1967073269","https://openalex.org/W1968807526","https://openalex.org/W1971646948","https://openalex.org/W1973665215","https://openalex.org/W1975883081","https://openalex.org/W1978136785","https://openalex.org/W1980164108","https://openalex.org/W1980262393","https://openalex.org/W1981687844","https://openalex.org/W1987841521","https://openalex.org/W1988642208","https://openalex.org/W1992275909","https://openalex.org/W1992707998","https://openalex.org/W1993115593","https://openalex.org/W1998464495","https://openalex.org/W1998962920","https://openalex.org/W2000266693","https://openalex.org/W2000388696","https://openalex.org/W2000752344","https://openalex.org/W2000834175","https://openalex.org/W2003961645","https://openalex.org/W2008765994","https://openalex.org/W2010797404","https://openalex.org/W2011207525","https://openalex.org/W2011596174","https://openalex.org/W2012411223","https://openalex.org/W2017775132","https://openalex.org/W2017915061","https://openalex.org/W2023853843","https://openalex.org/W2024359623","https://openalex.org/W2024535650","https://openalex.org/W2024884176","https://openalex.org/W2029104172","https://openalex.org/W2029135027","https://openalex.org/W2029787650","https://openalex.org/W2032730360","https://openalex.org/W2034077900","https://openalex.org/W2035851364","https://openalex.org/W2038729814","https://openalex.org/W2046262394","https://openalex.org/W2046633980","https://openalex.org/W2050156572","https://openalex.org/W2054537975","https://openalex.org/W2054637678","https://openalex.org/W2063554961","https://openalex.org/W2063785663","https://openalex.org/W2067900905","https://openalex.org/W2068109582","https://openalex.org/W2071110001","https://openalex.org/W2073464951","https://openalex.org/W2078872869","https://openalex.org/W2081635117","https://openalex.org/W2082539553","https://openalex.org/W2082829209","https://openalex.org/W2086477875","https://openalex.org/W2086808879","https://openalex.org/W2088120395","https://openalex.org/W2090670781","https://openalex.org/W2091661027","https://openalex.org/W2091794918","https://openalex.org/W2092130438","https://openalex.org/W2092846883","https://openalex.org/W2094839206","https://openalex.org/W2095668363","https://openalex.org/W2096262922","https://openalex.org/W2111448154","https://openalex.org/W2116955406","https://openalex.org/W2121372562","https://openalex.org/W2127006597","https://openalex.org/W2141492848","https://openalex.org/W2144917072","https://openalex.org/W2151810319","https://openalex.org/W2156550757","https://openalex.org/W2161127497","https://openalex.org/W2167627090","https://openalex.org/W2169764921","https://openalex.org/W2233318838","https://openalex.org/W2241303184","https://openalex.org/W2399538424","https://openalex.org/W2399707516","https://openalex.org/W2412113474","https://openalex.org/W2416492580","https://openalex.org/W2440587741","https://openalex.org/W2483464978","https://openalex.org/W2946554112","https://openalex.org/W3025295781","https://openalex.org/W4245939111","https://openalex.org/W6677965304","https://openalex.org/W6685192623","https://openalex.org/W6830480746"],"related_works":["https://openalex.org/W2360279915","https://openalex.org/W2581434848","https://openalex.org/W2017101370","https://openalex.org/W2120357935","https://openalex.org/W2413187295","https://openalex.org/W4389461963","https://openalex.org/W2385657022","https://openalex.org/W2371982023","https://openalex.org/W2390919492","https://openalex.org/W1564576128"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}