{"id":"https://openalex.org/W2062713622","doi":"https://doi.org/10.1039/c4ra00083h","title":"Nanofibrous electroactive scaffolds from a chitosan-grafted-aniline tetramer by electrospinning for tissue engineering","display_name":"Nanofibrous electroactive scaffolds from a chitosan-grafted-aniline tetramer by electrospinning for tissue engineering","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2062713622","doi":"https://doi.org/10.1039/c4ra00083h","mag":"2062713622"},"language":"en","primary_location":{"id":"doi:10.1039/c4ra00083h","doi":"https://doi.org/10.1039/c4ra00083h","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c4ra00083h","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100866831","display_name":"Xiaojie Ma","orcid":"https://orcid.org/0009-0006-4749-5137","observed_orcids":["https://orcid.org/0009-0006-4749-5137","https://orcid.org/0009-0006-0979-6473"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaojie Ma","raw_affiliation_strings":["Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104594339","display_name":"Juan Ge","orcid":"https://orcid.org/0000-0002-2251-4286","observed_orcids":["https://orcid.org/0000-0002-2251-4286"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juan Ge","raw_affiliation_strings":["Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100380271","display_name":"Yan Li","orcid":"https://orcid.org/0000-0001-8141-9732","observed_orcids":["https://orcid.org/0000-0001-8141-9732","https://orcid.org/0000-0002-1015-0390"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Li","raw_affiliation_strings":["Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023992952","display_name":"Baolin Guo","orcid":"https://orcid.org/0000-0001-6756-1441","observed_orcids":["https://orcid.org/0000-0001-6756-1441"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Baolin Guo","raw_affiliation_strings":["Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068805457","display_name":"Peter X. Ma","orcid":"https://orcid.org/0000-0002-0191-9487","observed_orcids":["https://orcid.org/0000-0002-0191-9487","https://orcid.org/0000-0002-7264-1443"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Peter X. Ma","raw_affiliation_strings":["Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China","Department of Biologic and Materials Sciences, University of Michigan, 1011, North University Ave., Room 2209, Ann Arbor, MI 48109, USA","Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA","Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109, USA","Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, MI 48109, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Department of Biologic and Materials Sciences, University of Michigan, 1011, North University Ave., Room 2209, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023992952","https://openalex.org/A5068805457"],"corresponding_institution_ids":["https://openalex.org/I27837315","https://openalex.org/I87445476"],"apc_list":{"value":850,"currency":"GBP","value_usd":1042},"apc_paid":null,"fwci":4.801,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.96383158,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"4","issue":"26","first_page":"13652","last_page":"13652"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electrospun-nanofibers","display_name":"electrospun nanofibers","score":0.8569999933242798},{"id":"https://openalex.org/keywords/electroactive-scaffolds","display_name":"electroactive scaffolds","score":0.9300000071525574},{"id":"https://openalex.org/keywords/chitosan","display_name":"chitosan","score":0.6269999742507935},{"id":"https://openalex.org/keywords/aniline-tetramer","display_name":"aniline tetramer","score":0.8519999980926514},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.7200000286102295},{"id":"https://openalex.org/keywords/c2c12-myoblasts","display_name":"C2C12 myoblasts","score":0.9100000262260437},{"id":"https://openalex.org/keywords/chondrocytes","display_name":"chondrocytes","score":0.921999990940094},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.8690000176429749},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"biocompatibility","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.843590497970581},{"id":"https://openalex.org/C144796933","wikidata":"https://www.wikidata.org/wiki/Q1533542","display_name":"Electrospinning","level":3,"score":0.8104947805404663},{"id":"https://openalex.org/C91129048","wikidata":"https://www.wikidata.org/wiki/Q594196","display_name":"Nanofiber","level":2,"score":0.7881534099578857},{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.7360222339630127},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.6094081401824951},{"id":"https://openalex.org/C2779244968","wikidata":"https://www.wikidata.org/wiki/Q186414","display_name":"Aniline","level":2,"score":0.6050237417221069},{"id":"https://openalex.org/C2778886173","wikidata":"https://www.wikidata.org/wiki/Q53832","display_name":"Tetramer","level":3,"score":0.5566768646240234},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.5132858157157898},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.47730955481529236},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.46943095326423645},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.45403051376342773},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.44987714290618896},{"id":"https://openalex.org/C2777869211","wikidata":"https://www.wikidata.org/wiki/Q1147647","display_name":"Cyclic voltammetry","level":4,"score":0.4107668995857239},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38657212257385254},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.36984145641326904},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.32421576976776123},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.21420365571975708},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.15317445993423462},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.1432686746120453},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.14004391431808472},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.09958761930465698},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.04952871799468994},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/c4ra00083h","doi":"https://doi.org/10.1039/c4ra00083h","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c4ra00083h","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1649382389","https://openalex.org/W1963797217","https://openalex.org/W1965945160","https://openalex.org/W1968225074","https://openalex.org/W1971422409","https://openalex.org/W1972659765","https://openalex.org/W1974433772","https://openalex.org/W1974830712","https://openalex.org/W1975833234","https://openalex.org/W1976581198","https://openalex.org/W1977789935","https://openalex.org/W1978609960","https://openalex.org/W1984417662","https://openalex.org/W1987834227","https://openalex.org/W1992080220","https://openalex.org/W1994986226","https://openalex.org/W2001186725","https://openalex.org/W2001901378","https://openalex.org/W2007192124","https://openalex.org/W2021255359","https://openalex.org/W2021990649","https://openalex.org/W2025188750","https://openalex.org/W2028362491","https://openalex.org/W2030628567","https://openalex.org/W2032195777","https://openalex.org/W2033971575","https://openalex.org/W2035628294","https://openalex.org/W2040048481","https://openalex.org/W2041465820","https://openalex.org/W2043310171","https://openalex.org/W2052647448","https://openalex.org/W2062201850","https://openalex.org/W2063583999","https://openalex.org/W2067478222","https://openalex.org/W2067769556","https://openalex.org/W2074443133","https://openalex.org/W2077367853","https://openalex.org/W2082731174","https://openalex.org/W2084554859","https://openalex.org/W2087356384","https://openalex.org/W2091155679","https://openalex.org/W2103924242","https://openalex.org/W2106727463","https://openalex.org/W2114126007","https://openalex.org/W2133006086","https://openalex.org/W2133670322","https://openalex.org/W2138371775","https://openalex.org/W2141489905","https://openalex.org/W2151793068","https://openalex.org/W2322433245","https://openalex.org/W2332030987"],"related_works":["https://openalex.org/W2736100938","https://openalex.org/W2081731500","https://openalex.org/W3124344214","https://openalex.org/W2035136001","https://openalex.org/W2041465820","https://openalex.org/W2089033793","https://openalex.org/W2527346076","https://openalex.org/W2997695335","https://openalex.org/W2888443746","https://openalex.org/W65070326"],"abstract_inverted_index":{"Functional":[0],"degradable":[1],"biomimetic":[2],"scaffolds":[3,14],"have":[4],"great":[5],"potential":[6],"applications":[7],"in":[8],"tissue":[9],"regeneration.":[10],"Nanofibrous":[11],"electroactive":[12],"biodegradable":[13],"from":[15,77],"chitosan-grafted-aniline":[16],"tetramer":[17,38],"(CS\u2013AT)":[18],"were":[19,64,75],"fabricated":[20],"by":[21,29,52,88,109,124],"an":[22],"electrospinning":[23],"method.":[24],"The":[25,45,72,80,117],"CS\u2013AT":[26,48,78,84,105,142],"was":[27,50,86,107,122],"synthesized":[28],"amidation":[30],"reaction":[31],"between":[32],"the":[33,40,68,83,92,96,99,114,120,137,141,150],"carboxyl":[34],"group":[35,42],"of":[36,43,47,70,82,98,101,119,129,155],"aniline":[37],"and":[39,57,60,91,104,113,127,132,136,147,153],"amine":[41],"chitosan.":[44],"structure":[46],"copolymer":[49],"characterized":[51],"1H":[53],"NMR,":[54],"FT-IR,":[55],"TGA":[56],"XRD.":[58],"UV-vis":[59],"cyclic":[61],"voltammetry":[62],"tests":[63],"used":[65],"to":[66],"demonstrate":[67],"electroactivity":[69],"CS\u2013AT.":[71],"electrospun":[73],"nanofibers":[74,85,100],"created":[76],"solution.":[79],"morphology":[81],"observed":[87],"employing":[89],"SEM":[90],"results":[93,138],"illustrated":[94],"that":[95,140],"diameter":[97],"deposited":[102],"CS":[103],"samples":[106],"controlled":[108],"both":[110],"polymer":[111],"concentration":[112],"AT":[115],"content.":[116],"biocompatibility":[118,146],"materials":[121,143],"evaluated":[123],"cell":[125,151],"adhesion":[126,152],"proliferation":[128,154],"C2C12":[130,156],"myoblasts":[131],"dog":[133],"chondrocyte":[134],"cells,":[135],"demonstrated":[139],"had":[144],"good":[145],"greatly":[148],"enhanced":[149],"cells.":[157]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":7}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}