{"id":"https://openalex.org/W2062487828","doi":"https://doi.org/10.1118/1.4814409","title":"SU\u2010E\u2010J\u2010197: Tracking Tumor Response Over Treatment Course in IMRT and Proton Patients","display_name":"SU\u2010E\u2010J\u2010197: Tracking Tumor Response Over Treatment Course in IMRT and Proton Patients","publication_year":2013,"publication_date":"2013-06-01","ids":{"openalex":"https://openalex.org/W2062487828","doi":"https://doi.org/10.1118/1.4814409","mag":"2062487828"},"language":"en","primary_location":{"id":"doi:10.1118/1.4814409","doi":"https://doi.org/10.1118/1.4814409","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4814409","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053661942","display_name":"R Williamson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R Williamson","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038616193","display_name":"Laurence Edward Court","orcid":"https://orcid.org/0000-0002-3241-6145","observed_orcids":["https://orcid.org/0000-0002-3241-6145"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Court","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044401242","display_name":"L Zhang","orcid":"https://orcid.org/0009-0001-0293-3272","observed_orcids":["https://orcid.org/0009-0001-0293-3272"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Zhang","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086483620","display_name":"Zhongxing X. Liao","orcid":"https://orcid.org/0000-0002-2224-9478","observed_orcids":["https://orcid.org/0000-0002-2224-9478"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Z Liao","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041943880","display_name":"Radhe Mohan","orcid":"https://orcid.org/0000-0003-3746-4557","observed_orcids":["https://orcid.org/0000-0003-3746-4557"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R Mohan","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053963427","display_name":"Y Chen","orcid":"https://orcid.org/0000-0002-2588-0521","observed_orcids":["https://orcid.org/0000-0002-2588-0521"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y Chen","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058839299","display_name":"Peter A. Balter","orcid":"https://orcid.org/0000-0003-4806-8920","observed_orcids":["https://orcid.org/0000-0003-4806-8920"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P Balter","raw_affiliation_strings":["UT MD Anderson Cancer Center, Houston, TX","UT/MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"UT/MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20725051,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"40","issue":"6Part9","first_page":"196","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.9079999923706055},{"id":"https://openalex.org/keywords/tumor-volume-change","display_name":"tumor volume change","score":0.5559999942779541},{"id":"https://openalex.org/keywords/tumor-mass","display_name":"tumor mass","score":0.7179999947547913},{"id":"https://openalex.org/keywords/intensity-modulated-radiotherapy","display_name":"intensity-modulated radiotherapy","score":0.6399999856948853},{"id":"https://openalex.org/keywords/proton-therapy","display_name":"proton therapy","score":0.9710000157356262},{"id":"https://openalex.org/keywords/passively-scattered-proton-therapy","display_name":"passively scattered proton therapy","score":0.8169999718666077},{"id":"https://openalex.org/keywords/4d-ct","display_name":"4D-CT","score":0.7720000147819519},{"id":"https://openalex.org/keywords/deformable-image-registration","display_name":"deformable image registration","score":0.9070000052452087},{"id":"https://openalex.org/keywords/concurrent-chemoradiotherapy","display_name":"concurrent chemoradiotherapy","score":0.8629999756813049},{"id":"https://openalex.org/keywords/hypofractionated-radiotherapy","display_name":"hypofractionated radiotherapy","score":0.6470000147819519},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.5329999923706055}],"concepts":[{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.7738488912582397},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6497218608856201},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.60628741979599},{"id":"https://openalex.org/C2779244869","wikidata":"https://www.wikidata.org/wiki/Q507667","display_name":"Proton therapy","level":3,"score":0.5775786638259888},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.4936703145503998},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3245292901992798}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1118/1.4814409","doi":"https://doi.org/10.1118/1.4814409","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4814409","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7400000095367432}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2461957038","https://openalex.org/W2053144828","https://openalex.org/W3035904869","https://openalex.org/W2050722109","https://openalex.org/W2089143449","https://openalex.org/W1013145701","https://openalex.org/W4231988004","https://openalex.org/W2003305474","https://openalex.org/W4389179299","https://openalex.org/W2041795146"],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"assess":[2],"the":[3,24,69,84,87,92,95,106,121,152,200,210,234],"changes":[4],"in":[5,56,230],"tumor":[6],"mass":[7,150],"and":[8,116,140,149,156,164,170,174,220],"volume":[9,115,148],"for":[10,102,168,178],"NSCLC":[11],"patients":[12,31,134],"treated":[13,36,137,188],"with":[14,32,44,60,138,142,189],"either":[15,50],"protons":[16,219],"or":[17,53],"IMRT.":[18],"Methods:":[19],"Analyses":[20],"were":[21,111,136,159],"done":[22],"on":[23,37,71,203],"T50":[25],"phase":[26],"from":[27,94,120],"weekly":[28],"4DCTs":[29],"of":[30,86,91,128,146,212],"stage":[33],"3":[34],"NSCCLC":[35],"an":[38],"IRB":[39],"approved":[40],"trial":[41],"comparing":[42],"IMRT":[43,139,169,221],"passively":[45],"scattered":[46],"protons.":[47,143,179],"Patients":[48],"received":[49],"74":[51],"GY":[52],"66":[54],"Gy":[55,58],"2":[57,193],"fractions":[59],"concurrent":[61,190],"chemotherapy.":[62],"We":[63,131,181],"performed":[64],"deformable":[65,75],"registration":[66,76,81],"to":[67,82,100,113],"segment":[68],"GTV":[70,88,147],"each":[72],"CT.":[73],"The":[74,108,144],"process":[77],"was":[78,216,223],"1)":[79],"rigid":[80],"determine":[83,114],"region":[85],"2)":[89],"deformation":[90],"contours":[93,110],"planning":[96,157],"CT":[97,155,158],"3)":[98],"thresholding":[99],"account":[101],"cavities":[103],"formed":[104],"inside":[105],"GTV.":[107],"resultant":[109],"used":[112],"mass,":[117],"as":[118],"determined":[119],"TPSs":[122],"CT\u2010to\u2010density":[123],"curve,":[124],"change":[125],"over":[126],"course":[127],"treatment.":[129,213],"Results:":[130],"analyzed":[132],"48":[133],"30":[135],"18":[141],"ratio":[145],"between":[151,218],"final":[153],"week":[154],"0.80":[160],"\u00b1":[161,166,172,176],".21":[162],"%":[163],"0.77":[165],"0.25%":[167],"0.71":[171],"0.21%":[173],"0.66":[175],"0.24%":[177],"Conclusion:":[180],"found":[182],"that":[183,199],"tumors":[184],"shrank":[185],"20\u201030%":[186],"when":[187],"chemo\u2010radiotherapy":[191],"at":[192,209],"Gy/fraction.":[194],"In":[195],"addition":[196],"we":[197],"noted":[198,217],"remaining":[201],"tumor,":[202],"average,":[204],"had":[205],"a":[206],"lower":[207],"density":[208],"end":[211],"A":[214],"difference":[215],"but":[222],"not":[224],"statistically":[225],"significant.":[226],"This":[227],"work":[228],"was,":[229],"part,":[231],"funded":[232],"by":[233],"National":[235],"Cancer":[236],"Institute.":[237]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}
