{"id":"https://openalex.org/W2062344567","doi":"https://doi.org/10.1016/j.jaci.2007.01.045","title":"Allergic Rhinitis and its Impact on Asthma update: Allergen immunotherapy","display_name":"Allergic Rhinitis and its Impact on Asthma update: Allergen immunotherapy","publication_year":2007,"publication_date":"2007-04-01","ids":{"openalex":"https://openalex.org/W2062344567","doi":"https://doi.org/10.1016/j.jaci.2007.01.045","mag":"2062344567","pmid":"https://pubmed.ncbi.nlm.nih.gov/17418661"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2007.01.045","doi":"https://doi.org/10.1016/j.jaci.2007.01.045","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2007.01.045","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073839386","display_name":"Giovanni Passalacqua","orcid":"https://orcid.org/0000-0002-5139-3604","observed_orcids":["https://orcid.org/0000-0002-5139-3604"]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giovanni Passalacqua","raw_affiliation_strings":["Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy. passalacqua@unige.it","From Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa, Genoa, Italy. passalacqua@unige.it","institution_ids":["https://openalex.org/I83816512"]},{"raw_affiliation_string":"From Allergy and Respiratory Diseases, Department of Internal Medicine, University of Genoa","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043192106","display_name":"Stephen R. Durham","orcid":"https://orcid.org/0000-0001-5264-6207","observed_orcids":["https://orcid.org/0000-0001-5264-6207"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen R. Durham","raw_affiliation_strings":["Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College, London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College, London","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073839386"],"corresponding_institution_ids":["https://openalex.org/I83816512"],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":26.6568,"has_fulltext":false,"cited_by_count":277,"citation_normalized_percentile":{"value":0.99885518,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":100},"biblio":{"volume":"119","issue":"4","first_page":"881","last_page":"891"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.9190000295639038},{"id":"https://openalex.org/keywords/allergen-immunotherapy","display_name":"allergen immunotherapy","score":0.9710000157356262},{"id":"https://openalex.org/keywords/sublingual-immunotherapy","display_name":"sublingual immunotherapy","score":0.9779999852180481},{"id":"https://openalex.org/keywords/subcutaneous-immunotherapy","display_name":"subcutaneous immunotherapy","score":0.8899999856948853},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.5139999985694885},{"id":"https://openalex.org/keywords/immunotherapy-safety","display_name":"immunotherapy safety","score":0.7979999780654907},{"id":"https://openalex.org/keywords/adjuvants","display_name":"adjuvants","score":0.7929999828338623},{"id":"https://openalex.org/keywords/recombinant-allergens","display_name":"recombinant allergens","score":0.9760000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9118926525115967},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.7859834432601929},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.704216718673706},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6300976276397705},{"id":"https://openalex.org/C2779787640","wikidata":"https://www.wikidata.org/wiki/Q1641412","display_name":"Allergen immunotherapy","level":4,"score":0.5918681621551514},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5370399355888367},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5307037234306335},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.5097929835319519},{"id":"https://openalex.org/C2777037608","wikidata":"https://www.wikidata.org/wiki/Q1641412","display_name":"Sublingual immunotherapy","level":4,"score":0.48969605565071106},{"id":"https://openalex.org/C3020633164","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Allergic asthma","level":3,"score":0.4651511609554291},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4280220866203308},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.40199247002601624},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3910854458808899},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26047489047050476},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.08998844027519226}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003888","descriptor_name":"Desensitization, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006255","descriptor_name":"Rhinitis, Allergic, Seasonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006255","descriptor_name":"Rhinitis, Allergic, Seasonal","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012221","descriptor_name":"Rhinitis, Allergic, Perennial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012221","descriptor_name":"Rhinitis, Allergic, Perennial","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jaci.2007.01.045","doi":"https://doi.org/10.1016/j.jaci.2007.01.045","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2007.01.045","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:17418661","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17418661","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of allergy and clinical immunology","raw_type":"Comparative Study"},{"id":"pmh:oai:iris.unige.it:11567/334323","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11567/334323","pdf_url":null,"source":{"id":"https://openalex.org/S4377196291","display_name":"CINECA IRIS Institutial Research Information System (University of Genoa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I83816512","host_organization_name":"University of Genoa","host_organization_lineage":["https://openalex.org/I83816512"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":145,"referenced_works":["https://openalex.org/W120984530","https://openalex.org/W1524200221","https://openalex.org/W1615320989","https://openalex.org/W1641557591","https://openalex.org/W1921048215","https://openalex.org/W1921245875","https://openalex.org/W1942126698","https://openalex.org/W1964354442","https://openalex.org/W1964778935","https://openalex.org/W1966645815","https://openalex.org/W1966794651","https://openalex.org/W1969658977","https://openalex.org/W1971098378","https://openalex.org/W1972513797","https://openalex.org/W1973688027","https://openalex.org/W1974103230","https://openalex.org/W1974582619","https://openalex.org/W1976640573","https://openalex.org/W1977868567","https://openalex.org/W1978178793","https://openalex.org/W1983595494","https://openalex.org/W1984188413","https://openalex.org/W1984360617","https://openalex.org/W1984538699","https://openalex.org/W1984780114","https://openalex.org/W1984872163","https://openalex.org/W1984973837","https://openalex.org/W1986404685","https://openalex.org/W1986517239","https://openalex.org/W1987965730","https://openalex.org/W1988108338","https://openalex.org/W1988281337","https://openalex.org/W1988632600","https://openalex.org/W1989174122","https://openalex.org/W1990702493","https://openalex.org/W1990995622","https://openalex.org/W1993375385","https://openalex.org/W1993440776","https://openalex.org/W1993555827","https://openalex.org/W1994277369","https://openalex.org/W1996404326","https://openalex.org/W1996486949","https://openalex.org/W1997120806","https://openalex.org/W1997289406","https://openalex.org/W1998207718","https://openalex.org/W1999122064","https://openalex.org/W1999778475","https://openalex.org/W2000655876","https://openalex.org/W2000938547","https://openalex.org/W2005932415","https://openalex.org/W2007072285","https://openalex.org/W2009075542","https://openalex.org/W2009729976","https://openalex.org/W2013023354","https://openalex.org/W2013737029","https://openalex.org/W2014457158","https://openalex.org/W2014972792","https://openalex.org/W2015217102","https://openalex.org/W2016063789","https://openalex.org/W2017662463","https://openalex.org/W2018309112","https://openalex.org/W2018589247","https://openalex.org/W2018801169","https://openalex.org/W2019176388","https://openalex.org/W2021399618","https://openalex.org/W2022972217","https://openalex.org/W2023654440","https://openalex.org/W2027750887","https://openalex.org/W2030014293","https://openalex.org/W2031202979","https://openalex.org/W2032260549","https://openalex.org/W2033232206","https://openalex.org/W2033421115","https://openalex.org/W2036197283","https://openalex.org/W2039347132","https://openalex.org/W2042555734","https://openalex.org/W2046241981","https://openalex.org/W2046487092","https://openalex.org/W2049494708","https://openalex.org/W2051838691","https://openalex.org/W2052475583","https://openalex.org/W2052490983","https://openalex.org/W2059013940","https://openalex.org/W2060411425","https://openalex.org/W2062004139","https://openalex.org/W2068273967","https://openalex.org/W2068471769","https://openalex.org/W2069096507","https://openalex.org/W2069342459","https://openalex.org/W2069362757","https://openalex.org/W2071814570","https://openalex.org/W2071845238","https://openalex.org/W2072867511","https://openalex.org/W2074525021","https://openalex.org/W2077685041","https://openalex.org/W2079088504","https://openalex.org/W2085196853","https://openalex.org/W2086790367","https://openalex.org/W2086794365","https://openalex.org/W2087759162","https://openalex.org/W2089769663","https://openalex.org/W2091084174","https://openalex.org/W2094515279","https://openalex.org/W2096210343","https://openalex.org/W2098913651","https://openalex.org/W2104862634","https://openalex.org/W2104912844","https://openalex.org/W2105012236","https://openalex.org/W2105385767","https://openalex.org/W2108395554","https://openalex.org/W2109455334","https://openalex.org/W2110567864","https://openalex.org/W2112247895","https://openalex.org/W2112427090","https://openalex.org/W2116810696","https://openalex.org/W2117076737","https://openalex.org/W2118532682","https://openalex.org/W2123733113","https://openalex.org/W2123764936","https://openalex.org/W2124453651","https://openalex.org/W2125803815","https://openalex.org/W2128140264","https://openalex.org/W2128945530","https://openalex.org/W2132441138","https://openalex.org/W2135087799","https://openalex.org/W2142388937","https://openalex.org/W2147957152","https://openalex.org/W2150187523","https://openalex.org/W2152557049","https://openalex.org/W2153011983","https://openalex.org/W2154126700","https://openalex.org/W2154282257","https://openalex.org/W2154889919","https://openalex.org/W2155143888","https://openalex.org/W2155774990","https://openalex.org/W2156787187","https://openalex.org/W2158341249","https://openalex.org/W2159285246","https://openalex.org/W2162051917","https://openalex.org/W2166685437","https://openalex.org/W2171058206","https://openalex.org/W2171810208","https://openalex.org/W2276163348","https://openalex.org/W2312829609","https://openalex.org/W4313331640"],"related_works":["https://openalex.org/W2037967963","https://openalex.org/W2757311403","https://openalex.org/W2064502016","https://openalex.org/W2480902578","https://openalex.org/W2038157030","https://openalex.org/W4238058956","https://openalex.org/W1775077669","https://openalex.org/W2011357422","https://openalex.org/W1973188898","https://openalex.org/W35514448"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":20},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":24}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}