{"id":"https://openalex.org/W2062036166","doi":"https://doi.org/10.1159/000243840","title":"Factors Influencing Morbidity and Mortality in Infants with Severe Respiratory Distress Syndrome Treated with Single or Multiple Doses of a Natural Porcine Surfactant","display_name":"Factors Influencing Morbidity and Mortality in Infants with Severe Respiratory Distress Syndrome Treated with Single or Multiple Doses of a Natural Porcine Surfactant","publication_year":2009,"publication_date":"2009-09-30","ids":{"openalex":"https://openalex.org/W2062036166","doi":"https://doi.org/10.1159/000243840","mag":"2062036166","pmid":"https://pubmed.ncbi.nlm.nih.gov/1391262"},"language":"en","primary_location":{"id":"doi:10.1159/000243840","doi":"https://doi.org/10.1159/000243840","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000243840","pdf_url":null,"source":{"id":"https://openalex.org/S4210177455","display_name":"Biology of the Neonate","issn_l":"0006-3126","issn":["0006-3126","1421-9727"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of the Neonate","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058017552","display_name":"Egbert Herting","orcid":"https://orcid.org/0000-0002-7189-879X","observed_orcids":["https://orcid.org/0000-0002-7189-879X"]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"E. Herting","raw_affiliation_strings":["Department of Pediatrics, University of G\u00f6ttingen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of G\u00f6ttingen, FRG","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108135312","display_name":"Christian Paul Speer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C.P. Speer","raw_affiliation_strings":["Department of Pediatrics, University of G\u00f6ttingen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of G\u00f6ttingen, FRG","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041322461","display_name":"Karsten Harms","orcid":"https://orcid.org/0000-0002-8809-3250","observed_orcids":["https://orcid.org/0000-0002-8809-3250"]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"K. Harms","raw_affiliation_strings":["Department of Pediatrics, University of G\u00f6ttingen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of G\u00f6ttingen, FRG","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113603653","display_name":"Bengt Robertson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]},{"id":"https://openalex.org/I4210153733","display_name":"St G\u00f6ran's Children's Hospital","ror":"https://ror.org/05xhpce34","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210153733"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"B. Robertson","raw_affiliation_strings":["Research Unit for Experimental Perinatal Pathology and St. Goran's Children's Hospital, Stockholm,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Unit for Experimental Perinatal Pathology and St. Goran's Children's Hospital, Stockholm,","institution_ids":["https://openalex.org/I4210099778","https://openalex.org/I4210153733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054001084","display_name":"Tore Curstedt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802208705","display_name":"Danderyds sjukhus","ror":"https://ror.org/00hm9kt34","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2802208705","https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"T. Curstedt","raw_affiliation_strings":["Department of Clinical Chemistry, Danderyd Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry, Danderyd Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I2802208705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065325564","display_name":"Henry L. Halliday","orcid":"https://orcid.org/0000-0001-7978-4992","observed_orcids":["https://orcid.org/0000-0001-7978-4992"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H.L. Halliday","raw_affiliation_strings":["Royal Maternity Hospital, Belfast, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Maternity Hospital, Belfast, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009328372","display_name":"Daniele Compagnone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D. Compagnone","raw_affiliation_strings":["Department of Medical Statistics, University of G\u00f6ttingen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Statistics, University of G\u00f6ttingen, FRG","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040285474","display_name":"Olaf Gefeller","orcid":"https://orcid.org/0000-0002-8985-7582","observed_orcids":["https://orcid.org/0000-0002-8985-7582"]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"O. Gefeller","raw_affiliation_strings":["Department of Medical Statistics, University of G\u00f6ttingen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Statistics, University of G\u00f6ttingen, FRG","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089307063","display_name":"Garth McClure","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. McClure","raw_affiliation_strings":["Royal Maternity Hospital, Belfast, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Maternity Hospital, Belfast, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061460703","display_name":"Marvin Ellsworth Reid","orcid":"https://orcid.org/0000-0003-4005-9384","observed_orcids":["https://orcid.org/0000-0003-4005-9384"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Reid","raw_affiliation_strings":["Royal Maternity Hospital, Belfast, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Maternity Hospital, Belfast, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068155811","display_name":"Richard J. Tubman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Tubman","raw_affiliation_strings":["Royal Maternity Hospital, Belfast, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Maternity Hospital, Belfast, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026126884","display_name":"Peter Herin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]},{"id":"https://openalex.org/I4210153733","display_name":"St G\u00f6ran's Children's Hospital","ror":"https://ror.org/05xhpce34","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210153733"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"P. Herin","raw_affiliation_strings":["Research Unit for Experimental Perinatal Pathology and St. Goran's Children's Hospital, Stockholm,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Unit for Experimental Perinatal Pathology and St. Goran's Children's Hospital, Stockholm,","institution_ids":["https://openalex.org/I4210099778","https://openalex.org/I4210153733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111367365","display_name":"Gert Noack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099778","display_name":"Saint G\u00f6ran Hospital","ror":"https://ror.org/00x6s3a91","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099778"]},{"id":"https://openalex.org/I4210153733","display_name":"St G\u00f6ran's Children's Hospital","ror":"https://ror.org/05xhpce34","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210153733"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"G. Noack","raw_affiliation_strings":["Research Unit for Experimental Perinatal Pathology and St. Goran's Children's Hospital, Stockholm,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Unit for Experimental Perinatal Pathology and St. Goran's Children's Hospital, Stockholm,","institution_ids":["https://openalex.org/I4210099778","https://openalex.org/I4210153733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111941854","display_name":"Joke H. Kok","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Kok","raw_affiliation_strings":["Academisch Ziekenhuis, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academisch Ziekenhuis, Amsterdam, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085662302","display_name":"Janna G. Koppe","orcid":"https://orcid.org/0000-0001-8777-1446","observed_orcids":["https://orcid.org/0000-0001-8777-1446"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Koppe","raw_affiliation_strings":["Academisch Ziekenhuis, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academisch Ziekenhuis, Amsterdam, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011709639","display_name":"Loekie van Sonderen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. van Sonderen","raw_affiliation_strings":["Academisch Ziekenhuis, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academisch Ziekenhuis, Amsterdam, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070741052","display_name":"E. Laufk\u00f6tter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Laufk\u00f6tter","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027722782","display_name":"W. K\u00f6hler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. K\u00f6hler","raw_affiliation_strings":["University of Bonn,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Bonn,","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089628320","display_name":"Herbert Boenisch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114487","display_name":"Klinikum Braunschweig","ror":"https://ror.org/01k1p1v52","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210114487"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Boenisch","raw_affiliation_strings":["Community Hospital, Braunschweig"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Community Hospital, Braunschweig","institution_ids":["https://openalex.org/I4210114487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112709370","display_name":"K Albrecht","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Albrecht","raw_affiliation_strings":["Central Hospital, Bremen,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Hospital, Bremen,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063775699","display_name":"Claudia Roll","orcid":"https://orcid.org/0000-0002-7915-8286","observed_orcids":["https://orcid.org/0000-0002-7915-8286"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C. Roll","raw_affiliation_strings":["University of Essen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Essen, FRG","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078734079","display_name":"Ludwig Hanssler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"L. Hanssler","raw_affiliation_strings":["University of Essen, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Essen, FRG","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038607802","display_name":"Michaela Haim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095425","display_name":"Graz University Hospital","ror":"https://ror.org/00pw0pp06","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210095425"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"M. Haim","raw_affiliation_strings":["University Hospital, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital, Graz, Austria","institution_ids":["https://openalex.org/I4210095425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048253815","display_name":"Sidarto Bambang Oetomo","orcid":"https://orcid.org/0000-0002-1199-7390","observed_orcids":["https://orcid.org/0000-0002-1199-7390"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"S.B. Oetomo","raw_affiliation_strings":["University Hospital, Groningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital, Groningen, The Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109248551","display_name":"A Okken","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A. Okken","raw_affiliation_strings":["University Hospital, Groningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital, Groningen, The Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008374993","display_name":"P.C. Altfeld","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086003","display_name":"Kinderkrankenhaus auf der Bult","ror":"https://ror.org/00b06cz11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210086003"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P.C. Altfeld","raw_affiliation_strings":["Pediatric Hospital (Auf der Bult), Hannover,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Hospital (Auf der Bult), Hannover,","institution_ids":["https://openalex.org/I4210086003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048831847","display_name":"Peter Groneck","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Groneck","raw_affiliation_strings":["Pediatric Hospital K\u00f6ln,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Hospital K\u00f6ln,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061686530","display_name":"W. Kachel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Kachel","raw_affiliation_strings":["Pediatric Hospital, Mannheim, FRG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Hospital, Mannheim, FRG","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086438339","display_name":"Jean-Pierre Relier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J.P. Relier","raw_affiliation_strings":["University of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Paris, France","institution_ids":["https://openalex.org/I204730241"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071398122","display_name":"Herv\u00e9 Walti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"H. Walti","raw_affiliation_strings":["University of Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Paris, France","institution_ids":["https://openalex.org/I204730241"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":11,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0221,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.80212336,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"61 Suppl 1","issue":null,"first_page":"26","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11586","display_name":"Congenital Diaphragmatic Hernia Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.7979999780654907},{"id":"https://openalex.org/keywords/surfactant-replacement-therapy","display_name":"surfactant therapy","score":0.6800000071525574},{"id":"https://openalex.org/keywords/porcine-surfactant","display_name":"porcine surfactant","score":0.8980000019073486},{"id":"https://openalex.org/keywords/curosurf","display_name":"Curosurf","score":0.9620000123977661},{"id":"https://openalex.org/keywords/neonatal-mortality","display_name":"neonatal mortality","score":0.8289999961853027},{"id":"https://openalex.org/keywords/pneumothorax","display_name":"pneumothorax","score":0.9100000262260437},{"id":"https://openalex.org/keywords/intracranial-hemorrhage","display_name":"intracranial hemorrhage","score":0.8640000224113464},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.8849999904632568},{"id":"https://openalex.org/keywords/low-birth-weight","display_name":"low birth weight","score":0.906000018119812},{"id":"https://openalex.org/keywords/hypothermia","display_name":"hypothermia","score":0.828000009059906},{"id":"https://openalex.org/keywords/acidosis","display_name":"acidosis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/mechanical-ventilation","display_name":"mechanical ventilation","score":0.6600000262260437},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9089182019233704},{"id":"https://openalex.org/C141983124","wikidata":"https://www.wikidata.org/wiki/Q188008","display_name":"Respiratory distress","level":2,"score":0.6496999263763428},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.5544952154159546},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5129639506340027},{"id":"https://openalex.org/C2776953283","wikidata":"https://www.wikidata.org/wiki/Q17125052","display_name":"Surfactant therapy","level":4,"score":0.46781182289123535},{"id":"https://openalex.org/C2776348555","wikidata":"https://www.wikidata.org/wiki/Q344873","display_name":"ARDS","level":3,"score":0.42400991916656494},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.42230987548828125},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.42222100496292114},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.42096102237701416},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3797570466995239},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.17134344577789307},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.13209402561187744},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007230","descriptor_name":"Infant, Low Birth Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009017","descriptor_name":"Morbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011030","descriptor_name":"Pneumothorax","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011663","descriptor_name":"Pulmonary Surfactants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1159/000243840","doi":"https://doi.org/10.1159/000243840","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000243840","pdf_url":null,"source":{"id":"https://openalex.org/S4210177455","display_name":"Biology of the Neonate","issn_l":"0006-3126","issn":["0006-3126","1421-9727"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of the Neonate","raw_type":"journal-article"},{"id":"pmid:1391262","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1391262","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of the neonate","raw_type":"Clinical Trial"},{"id":"pmh:oai:pure.rug.nl:openaire_cris_publications/d775ea7d-ab96-4930-b79a-c949fa937702","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/d775ea7d-ab96-4930-b79a-c949fa937702","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/d775ea7d-ab96-4930-b79a-c949fa937702","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/d775ea7d-ab96-4930-b79a-c949fa937702","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biology of the neonate, 61, 26 - 30","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2063529396","https://openalex.org/W1989516830","https://openalex.org/W2013648784","https://openalex.org/W2062943735","https://openalex.org/W2084887794","https://openalex.org/W2473431719","https://openalex.org/W2151539137","https://openalex.org/W1987546432","https://openalex.org/W7034217080","https://openalex.org/W1954246662"],"abstract_inverted_index":{"In":[0],"an":[1,123],"international":[2],"multicenter":[3],"trial":[4],"infants":[5],"with":[6,122],"clinical":[7,72],"and":[8,70,76,90,116,136],"radiological":[9],"signs":[10],"of":[11,52,65,93,155],"severe":[12],"RDS":[13],"(age":[14],"2-15":[15],"h,":[16],"birthweight":[17],"700-2,000":[18],"g,":[19],"mechanical":[20],"ventilation,":[21],"FiO2":[22],"greater":[23],"than":[24,88,100,132,140],"or":[25,43],"equal":[26],"to":[27,34,45,143],"0.6,":[28],"no":[29],"complicating":[30],"disease)":[31],"were":[32,80,102,120],"randomized":[33],"receive":[35],"either":[36],"a":[37,53,59],"single":[38],"dose":[39],"(n":[40,49],"=":[41,50],"176)":[42],"up":[44],"three":[46],"subsequent":[47],"doses":[48],"167)":[51],"natural":[54],"porcine":[55],"surfactant":[56,144],"(Curosurf).":[57],"Using":[58],"logistic":[60],"regression":[61],"model,":[62],"the":[63,91,106,153],"effects":[64],"therapy,":[66],"birthweight,":[67,110,127],"sex,":[68],"hospital":[69,111],"other":[71],"factors":[73,151],"on":[74],"survival":[75],"various":[77],"outcome":[78],"parameters":[79],"evaluated.":[81],"Mortality":[82],"(13":[83],"vs.":[84,96],"21%,":[85],"p":[86,98],"less":[87,99,131,139],"0.05)":[89],"incidence":[92],"pneumothorax":[94],"(9":[95],"18%,":[97],"0.01)":[101],"significantly":[103],"lower":[104],"in":[105],"multiple-dose":[107],"group.":[108],"Low":[109,126],"allocation,":[112],"low":[113],"Apgar":[114],"score":[115],"initial":[117],"disease":[118],"severity":[119],"associated":[121],"increased":[124],"mortality.":[125],"hypothermia":[128],"(admission":[129],"temperature":[130],"36":[133],"degrees":[134],"C)":[135],"acidosis":[137],"(pH":[138],"7.25)":[141],"prior":[142],"treatment":[145],"could":[146],"be":[147],"identified":[148],"as":[149],"risk":[150],"for":[152],"development":[154],"intracranial":[156],"hemorrhage.":[157]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}