{"id":"https://openalex.org/W2061662225","doi":"https://doi.org/10.1007/s13566-012-0074-3","title":"Low-dose fractionated radiation with induction chemotherapy for locally advanced head and neck cancer: 5 year results of a prospective phase II trial","display_name":"Low-dose fractionated radiation with induction chemotherapy for locally advanced head and neck cancer: 5 year results of a prospective phase II trial","publication_year":2012,"publication_date":"2012-10-19","ids":{"openalex":"https://openalex.org/W2061662225","doi":"https://doi.org/10.1007/s13566-012-0074-3","mag":"2061662225","pmid":"https://pubmed.ncbi.nlm.nih.gov/26052405","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4457337"},"language":"en","primary_location":{"id":"doi:10.1007/s13566-012-0074-3","doi":"https://doi.org/10.1007/s13566-012-0074-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13566-012-0074-3","pdf_url":"https://link.springer.com/content/pdf/10.1007%2Fs13566-012-0074-3.pdf","source":{"id":"https://openalex.org/S2764830874","display_name":"Journal of Radiation Oncology","issn_l":"1948-7894","issn":["1948-7894","1948-7908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Radiation Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007%2Fs13566-012-0074-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111925239","display_name":"John F. Gleason","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I2802239656","display_name":"Markey Cancer Center","ror":"https://ror.org/01dhvva97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2802239656"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John F. Gleason","raw_affiliation_strings":["Department of Radiation Medicine, University of Kentucky, Markey Cancer Center, Lexington, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Medicine, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2802239656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042036789","display_name":"Mahesh R. Kudrimoti","orcid":"https://orcid.org/0000-0001-7251-2687","observed_orcids":["https://orcid.org/0000-0001-7251-2687"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I2802239656","display_name":"Markey Cancer Center","ror":"https://ror.org/01dhvva97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2802239656"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahesh Kudrimoti","raw_affiliation_strings":["Department of Radiation Medicine, University of Kentucky, Markey Cancer Center, Lexington, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Medicine, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2802239656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084235817","display_name":"Emily Van Meter Dressler","orcid":"https://orcid.org/0000-0002-6054-7839","observed_orcids":["https://orcid.org/0000-0002-6054-7839"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I2802239656","display_name":"Markey Cancer Center","ror":"https://ror.org/01dhvva97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2802239656"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily M. Van Meter","raw_affiliation_strings":["Division of Cancer Biostatistics, University of Kentucky, Markey Cancer Center, Lexington, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Biostatistics, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2802239656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079124490","display_name":"Mohammed Mohiuddin","orcid":"https://orcid.org/0000-0002-1825-4661","observed_orcids":["https://orcid.org/0000-0002-1825-4661"]},"institutions":[{"id":"https://openalex.org/I2800965796","display_name":"King Faisal Specialist Hospital & Research Centre","ror":"https://ror.org/05n0wgt02","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I2800965796"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Mohammed Mohiuddin","raw_affiliation_strings":["King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I2800965796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070621756","display_name":"William F. Regine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William F. Regine","raw_affiliation_strings":["Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112084547","display_name":"Joseph P. Valentino","orcid":"https://orcid.org/0000-0002-5719-1640","observed_orcids":["https://orcid.org/0000-0002-5719-1640"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I2802239656","display_name":"Markey Cancer Center","ror":"https://ror.org/01dhvva97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2802239656"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Valentino","raw_affiliation_strings":["Department of Otolaryngology HNS, University of Kentucky, Markey Cancer Center, Lexington, KY, USA; Department of Surgery, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","Department of Otolaryngology HNS, University of Kentucky, Markey Cancer Center, Lexington, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology HNS, University of Kentucky, Markey Cancer Center, Lexington, KY, USA; Department of Surgery, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2802239656"]},{"raw_affiliation_string":"Department of Otolaryngology HNS, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2802239656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013997983","display_name":"Daniel E. Kenady","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]},{"id":"https://openalex.org/I2802239656","display_name":"Markey Cancer Center","ror":"https://ror.org/01dhvva97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2802239656"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Kenady","raw_affiliation_strings":["Division of General Surgery, Department of Surgery, University of Kentucky, Markey Cancer Center, Lexington, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Surgery, Department of Surgery, University of Kentucky, Markey Cancer Center, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722","https://openalex.org/I2802239656"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030064179","display_name":"Susanne M. Arnold","orcid":"https://orcid.org/0000-0001-6542-9551","observed_orcids":["https://orcid.org/0000-0001-6542-9551"]},"institutions":[{"id":"https://openalex.org/I2802239656","display_name":"Markey Cancer Center","ror":"https://ror.org/01dhvva97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285210727","https://openalex.org/I143302722","https://openalex.org/I2802239656"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Susanne M. Arnold","raw_affiliation_strings":["Division of Medical Oncology, Department of Internal Medicine, Markey Cancer Center, cc445, 800 Rose Street, Lexington, KY 40536, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Oncology, Department of Internal Medicine, Markey Cancer Center, cc445, 800 Rose Street, Lexington, KY 40536, USA","institution_ids":["https://openalex.org/I2802239656"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030064179"],"corresponding_institution_ids":["https://openalex.org/I2802239656"],"apc_list":{"value":3280,"currency":"USD","value_usd":3280},"apc_paid":null,"fwci":0.6579,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.7134104,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"2","issue":"1","first_page":"35","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/induction-chemotherapy","display_name":"induction chemotherapy","score":0.7350000143051147},{"id":"https://openalex.org/keywords/locally-advanced-head-and-neck-squamous-cell-carcinoma","display_name":"locally advanced head and neck squamous cell carcinoma","score":0.9279999732971191},{"id":"https://openalex.org/keywords/paclitaxel","display_name":"paclitaxel","score":0.9670000076293945},{"id":"https://openalex.org/keywords/carboplatin","display_name":"carboplatin","score":1.0},{"id":"https://openalex.org/keywords/concurrent-chemoradiotherapy","display_name":"concurrent chemoradiotherapy","score":0.8610000014305115},{"id":"https://openalex.org/keywords/locoregional-control","display_name":"locoregional control","score":0.9480000138282776},{"id":"https://openalex.org/keywords/remote-control","display_name":"remote control","score":0.699999988079071},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9279999732971191},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.8230000138282776},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9292811155319214},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.7817384004592896},{"id":"https://openalex.org/C2776611710","wikidata":"https://www.wikidata.org/wiki/Q16888295","display_name":"Induction chemotherapy","level":3,"score":0.7586688995361328},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.7584912180900574},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5992451310157776},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5736455321311951},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.5423141717910767},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.541205883026123},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4839234948158264},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4069358706474304},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.32526683807373047},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3072414994239807}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/s13566-012-0074-3","doi":"https://doi.org/10.1007/s13566-012-0074-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13566-012-0074-3","pdf_url":"https://link.springer.com/content/pdf/10.1007%2Fs13566-012-0074-3.pdf","source":{"id":"https://openalex.org/S2764830874","display_name":"Journal of Radiation Oncology","issn_l":"1948-7894","issn":["1948-7894","1948-7908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Radiation Oncology","raw_type":"journal-article"},{"id":"pmid:26052405","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26052405","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of radiation oncology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4457337","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4457337","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Radiat Oncol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s13566-012-0074-3","doi":"https://doi.org/10.1007/s13566-012-0074-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13566-012-0074-3","pdf_url":"https://link.springer.com/content/pdf/10.1007%2Fs13566-012-0074-3.pdf","source":{"id":"https://openalex.org/S2764830874","display_name":"Journal of Radiation Oncology","issn_l":"1948-7894","issn":["1948-7894","1948-7908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Radiation Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G9000134899","display_name":"University of Kentucky Markey Cancer Center \u2013 Cancer Center Support Grant","funder_award_id":"P30CA177558","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2061662225.pdf","grobid_xml":"https://content.openalex.org/works/W2061662225.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1565276921","https://openalex.org/W1963776078","https://openalex.org/W1975664090","https://openalex.org/W1983970003","https://openalex.org/W2013944496","https://openalex.org/W2022173560","https://openalex.org/W2036005555","https://openalex.org/W2043966544","https://openalex.org/W2054351351","https://openalex.org/W2059275582","https://openalex.org/W2061759798","https://openalex.org/W2063142791","https://openalex.org/W2067758224","https://openalex.org/W2089257078","https://openalex.org/W2095120446","https://openalex.org/W2096609221","https://openalex.org/W2100961085","https://openalex.org/W2103151974","https://openalex.org/W2118003229","https://openalex.org/W2120068217","https://openalex.org/W2122035130","https://openalex.org/W2141592118","https://openalex.org/W2142222095","https://openalex.org/W2145078756","https://openalex.org/W2146407643","https://openalex.org/W2155384808","https://openalex.org/W2172200669","https://openalex.org/W2266670220","https://openalex.org/W2582743722"],"related_works":["https://openalex.org/W2242003941","https://openalex.org/W2464757962","https://openalex.org/W2093063361","https://openalex.org/W2590633614","https://openalex.org/W2109532212","https://openalex.org/W2053917375","https://openalex.org/W2061759798","https://openalex.org/W4250441545","https://openalex.org/W4246795623","https://openalex.org/W3080484379"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}