{"id":"https://openalex.org/W2061590874","doi":"https://doi.org/10.1002/mrm.20461","title":"Accurate myocardial T1 measurements: Toward quantification of myocardial blood flow with arterial spin labeling","display_name":"Accurate myocardial T1 measurements: Toward quantification of myocardial blood flow with arterial spin labeling","publication_year":2005,"publication_date":"2005-04-20","ids":{"openalex":"https://openalex.org/W2061590874","doi":"https://doi.org/10.1002/mrm.20461","mag":"2061590874","pmid":"https://pubmed.ncbi.nlm.nih.gov/15844151"},"language":"en","primary_location":{"id":"doi:10.1002/mrm.20461","doi":"https://doi.org/10.1002/mrm.20461","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mrm.20461","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.20461","source":{"id":"https://openalex.org/S111160002","display_name":"Magnetic Resonance in Medicine","issn_l":"0740-3194","issn":["0740-3194","1522-2594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic Resonance in Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.20461","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052410576","display_name":"Haosen Zhang","orcid":"https://orcid.org/0009-0006-8249-317X","observed_orcids":["https://orcid.org/0009-0006-8249-317X"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Haosen Zhang","raw_affiliation_strings":["Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO 63110, USA. zhangh@mir.wustl.edu","Mallinckrodt Institute of Radiology Washington University  St. Louis Missouri USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO 63110, USA. zhangh@mir.wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Mallinckrodt Institute of Radiology Washington University  St. Louis Missouri USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078163432","display_name":"Steven M. Shea","orcid":"https://orcid.org/0000-0002-0360-4884","observed_orcids":["https://orcid.org/0000-0002-0360-4884"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve M. Shea","raw_affiliation_strings":["Northwestern University, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northwestern University, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030376669","display_name":"Vivian Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vivian Park","raw_affiliation_strings":["Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101930940","display_name":"Debiao Li","orcid":"https://orcid.org/0000-0001-8560-8231","observed_orcids":["https://orcid.org/0000-0001-8560-8231"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Debiao Li","raw_affiliation_strings":["Northwestern University, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northwestern University, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050980874","display_name":"Pamela K. Woodard","orcid":"https://orcid.org/0000-0001-9012-0812","observed_orcids":["https://orcid.org/0000-0001-9012-0812"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela K. Woodard","raw_affiliation_strings":["Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001700323","display_name":"Robert J. Gropler","orcid":"https://orcid.org/0000-0002-6550-0570","observed_orcids":["https://orcid.org/0000-0002-6550-0570"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert J. Gropler","raw_affiliation_strings":["Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079200067","display_name":"Jie Zheng","orcid":"https://orcid.org/0000-0002-2310-2996","observed_orcids":["https://orcid.org/0000-0002-2310-2996"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Zheng","raw_affiliation_strings":["Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052410576"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":null,"fwci":1.7829,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.83788588,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"53","issue":"5","first_page":"1135","last_page":"1142"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.010300000198185444,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12603","display_name":"NMR spectroscopy and applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3106","display_name":"Nuclear and High Energy Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocardial-t1-mapping","display_name":"myocardial T1 mapping","score":0.8679999709129333},{"id":"https://openalex.org/keywords/arterial-spin-labeling","display_name":"arterial spin labeling","score":0.953000009059906},{"id":"https://openalex.org/keywords/myocardial-blood-flow-quantification","display_name":"myocardial blood flow quantification","score":0.9919999837875366},{"id":"https://openalex.org/keywords/saturation-magnetization","display_name":"saturation magnetization","score":0.6779999732971191},{"id":"https://openalex.org/keywords/multivariable-regression","display_name":"multivariable regression","score":0.8069999814033508},{"id":"https://openalex.org/keywords/coronary-stenosis","display_name":"coronary artery stenosis","score":0.8690000176429749},{"id":"https://openalex.org/keywords/perfusion-reserve","display_name":"perfusion reserve","score":0.7519999742507935},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5691156387329102},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.5683711171150208},{"id":"https://openalex.org/C3018723549","wikidata":"https://www.wikidata.org/wiki/Q56284158","display_name":"Arterial spin labeling","level":3,"score":0.49345484375953674},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.46686363220214844},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.42865097522735596},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.4149261713027954},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.37738606333732605},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2656136155128479},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.25089991092681885},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17686104774475098}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013113","descriptor_name":"Spin Labels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023921","descriptor_name":"Coronary Stenosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/mrm.20461","doi":"https://doi.org/10.1002/mrm.20461","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mrm.20461","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.20461","source":{"id":"https://openalex.org/S111160002","display_name":"Magnetic Resonance in Medicine","issn_l":"0740-3194","issn":["0740-3194","1522-2594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic Resonance in Medicine","raw_type":"journal-article"},{"id":"pmid:15844151","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15844151","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic resonance in medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/mrm.20461","doi":"https://doi.org/10.1002/mrm.20461","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mrm.20461","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.20461","source":{"id":"https://openalex.org/S111160002","display_name":"Magnetic Resonance in Medicine","issn_l":"0740-3194","issn":["0740-3194","1522-2594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnetic Resonance in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2061590874.pdf","grobid_xml":"https://content.openalex.org/works/W2061590874.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1965768492","https://openalex.org/W1967806904","https://openalex.org/W1969087514","https://openalex.org/W1972990545","https://openalex.org/W1978856658","https://openalex.org/W1979245246","https://openalex.org/W1979935420","https://openalex.org/W1985036246","https://openalex.org/W2007706876","https://openalex.org/W2012539218","https://openalex.org/W2027981703","https://openalex.org/W2034045946","https://openalex.org/W2036951583","https://openalex.org/W2051970933","https://openalex.org/W2056187201","https://openalex.org/W2058704964","https://openalex.org/W2061101635","https://openalex.org/W2062010489","https://openalex.org/W2062142772","https://openalex.org/W2064015715","https://openalex.org/W2072127166","https://openalex.org/W2084593331","https://openalex.org/W2092901704","https://openalex.org/W2092914618","https://openalex.org/W2096691889","https://openalex.org/W2100042237","https://openalex.org/W2103476848","https://openalex.org/W2121983741","https://openalex.org/W2125587122","https://openalex.org/W2130872658","https://openalex.org/W2161044358","https://openalex.org/W2161061318","https://openalex.org/W2326325773"],"related_works":["https://openalex.org/W7095152561","https://openalex.org/W2884483336","https://openalex.org/W2126421225","https://openalex.org/W2067837553","https://openalex.org/W4416292556","https://openalex.org/W4386437777","https://openalex.org/W4390743378","https://openalex.org/W2013241830","https://openalex.org/W2519241172","https://openalex.org/W2051255429"],"abstract_inverted_index":{"In":[0,109,129,139,192],"this":[1],"study,":[2,112],"we":[3],"investigated":[4],"a":[5,43,49,73,86,119,175],"method":[6],"for":[7,12,57,93,214],"accurately":[8],"measuring":[9],"myocardial":[10,16,46,209],"T(1)":[11,80,116,199,210],"the":[13,58,94,110,113,132,149,168,181,194],"quantification":[14],"of":[15,45,78,115,127,143,156,208],"blood":[17],"flow":[18],"(MBF)":[19],"with":[20,31,72,97,118],"arterial":[21],"spin":[22],"labeling":[23],"(ASL).":[24],"A":[25,51,171],"single-shot":[26],"gradient-echo":[27],"(GE)-based":[28],"ASL":[29,182,196],"sequence":[30],"an":[32,205],"adiabatic":[33],"hyperbolic":[34],"secant":[35],"inversion":[36,121],"recovery":[37],"pulse":[38,123],"was":[39,62,69,82,124],"modified":[40,195],"to":[41,64],"acquire":[42],"pair":[44],"T(1)'s":[47],"within":[48,125],"breath-hold.":[50],"multivariable":[52],"regression":[53,200],"algorithm":[54,201],"that":[55],"accounted":[56],"magnetization":[59],"saturation":[60],"effects":[61],"developed":[63],"calculate":[65],"T(1).":[66],"The":[67,76],"MBF":[68,95,133,144,179,217],"then":[70,89],"determined":[71],"well-developed":[74],"model.":[75],"accuracy":[77,114],"our":[79],"calculation":[81],"first":[83],"evaluated":[84],"in":[85,90,148,160,167,178,186],"phantom,":[87],"and":[88,101,163,183,189,198,211],"six":[91],"dogs":[92,151],"calculation,":[96],"(N":[98,103],"=":[99,104],"4)":[100],"without":[102],"2)":[105],"coronary":[106],"artery":[107],"stenosis.":[108],"phantom":[111],"measured":[117],"slice-selective":[120],"prepared":[122],"2.5%":[126],"error.":[128],"healthy":[130,188],"dogs,":[131],"increased":[134],"2-5":[135],"times":[136],"during":[137,152],"vasodilation.":[138],"contrast,":[140],"regional":[141],"differences":[142],"were":[145],"well":[146],"visualized":[147],"stenotic":[150,169,190],"vasodilation":[153],"(perfusion":[154],"reserve":[155],"2.75":[157],"+/-":[158,165],"0.83":[159],"normal":[161],"myocardium,":[162],"1.46":[164],"0.75":[166],"area).":[170],"correlation":[172],"analysis":[173],"revealed":[174],"close":[176],"agreement":[177],"between":[180],"microsphere":[184],"(MS)":[185],"both":[187],"dogs.":[191],"summary,":[193],"technique":[197],"proposed":[202],"here":[203],"provide":[204],"accurate":[206],"measurement":[207],"demonstrate":[212],"potential":[213],"reliably":[215],"assessing":[216],"at":[218],"steady":[219],"state.":[220]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}