{"id":"https://openalex.org/W2061464673","doi":"https://doi.org/10.1016/j.jscs.2011.12.026","title":"Antioxidant and cytotoxic activities of essential oil of Ocimum canum Sims. from India","display_name":"Antioxidant and cytotoxic activities of essential oil of Ocimum canum Sims. from India","publication_year":2012,"publication_date":"2012-01-09","ids":{"openalex":"https://openalex.org/W2061464673","doi":"https://doi.org/10.1016/j.jscs.2011.12.026","mag":"2061464673"},"language":"en","primary_location":{"id":"doi:10.1016/j.jscs.2011.12.026","doi":"https://doi.org/10.1016/j.jscs.2011.12.026","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jscs.2011.12.026","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1319610312000026/pdf","source":{"id":"https://openalex.org/S77754710","display_name":"Journal of Saudi Chemical Society","issn_l":"1319-6103","issn":["1319-6103","2212-4640"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Saudi Chemical Society","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S1319610312000026/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019731085","display_name":"M. Tamil Selvi","orcid":"https://orcid.org/0009-0008-0884-2735","observed_orcids":["https://orcid.org/0009-0008-0884-2735"]},"institutions":[{"id":"https://openalex.org/I4405268639","display_name":"Kongunadu Arts and Science College","ror":"https://ror.org/01kkz4038","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405268639"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M. Tamil Selvi","raw_affiliation_strings":["PG and Research Department of Biotechnology, Kongunadu Arts and Science College, GN Mills, Coimbatore 641 029, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PG and Research Department of Biotechnology, Kongunadu Arts and Science College, GN Mills, Coimbatore 641 029, Tamil Nadu, India","institution_ids":["https://openalex.org/I4405268639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017310367","display_name":"Ramaraj Thirugnanasampandan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405268639","display_name":"Kongunadu Arts and Science College","ror":"https://ror.org/01kkz4038","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405268639"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"R. Thirugnanasampandan","raw_affiliation_strings":["PG and Research Department of Biotechnology, Kongunadu Arts and Science College, GN Mills, Coimbatore 641 029, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PG and Research Department of Biotechnology, Kongunadu Arts and Science College, GN Mills, Coimbatore 641 029, Tamil Nadu, India","institution_ids":["https://openalex.org/I4405268639"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087146697","display_name":"S. Sundarammal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405268639","display_name":"Kongunadu Arts and Science College","ror":"https://ror.org/01kkz4038","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405268639"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S. Sundarammal","raw_affiliation_strings":["PG and Research Department of Biotechnology, Kongunadu Arts and Science College, GN Mills, Coimbatore 641 029, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PG and Research Department of Biotechnology, Kongunadu Arts and Science College, GN Mills, Coimbatore 641 029, Tamil Nadu, India","institution_ids":["https://openalex.org/I4405268639"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5017310367"],"corresponding_institution_ids":["https://openalex.org/I4405268639"],"apc_list":{"value":2490,"currency":"USD","value_usd":2490},"apc_paid":{"value":2490,"currency":"USD","value_usd":2490},"fwci":2.6341,"has_fulltext":true,"cited_by_count":66,"citation_normalized_percentile":{"value":0.87914578,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"19","issue":"1","first_page":"97","last_page":"100"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.8330000042915344,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.8330000042915344,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.1298000067472458,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.02410000003874302,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ocimum-canum","display_name":"Ocimum canum","score":1.0},{"id":"https://openalex.org/keywords/essential-oils","display_name":"essential oils","score":0.9860000014305115},{"id":"https://openalex.org/keywords/camphor","display_name":"camphor","score":0.7850000262260437},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8169999718666077},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9660000205039978},{"id":"https://openalex.org/keywords/free-radical-scavenging-activity","display_name":"free radical scavenging","score":0.8159999847412109},{"id":"https://openalex.org/keywords/metal-chelating-activity","display_name":"metal chelating activity","score":0.8659999966621399},{"id":"https://openalex.org/keywords/dna-fragmentation","display_name":"DNA fragmentation","score":0.7960000038146973},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.8790000081062317},{"id":"https://openalex.org/keywords/leaf-chemical-composition","display_name":"leaf chemical composition","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8144410848617554},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.7885184288024902},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7852286100387573},{"id":"https://openalex.org/C2777709666","wikidata":"https://www.wikidata.org/wiki/Q192454","display_name":"Deoxyribose","level":3,"score":0.7485578656196594},{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.7357200384140015},{"id":"https://openalex.org/C2780697445","wikidata":"https://www.wikidata.org/wiki/Q181559","display_name":"Camphor","level":2,"score":0.6139433979988098},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.5284982323646545},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.5252518057823181},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5081276893615723},{"id":"https://openalex.org/C2779342943","wikidata":"https://www.wikidata.org/wiki/Q148818","display_name":"Ocimum","level":2,"score":0.45125189423561096},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4357434809207916},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.4196087121963501},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4014405310153961},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3616703152656555},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.32735157012939453},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3042711913585663},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2932431697845459},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07602396607398987},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jscs.2011.12.026","doi":"https://doi.org/10.1016/j.jscs.2011.12.026","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jscs.2011.12.026","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1319610312000026/pdf","source":{"id":"https://openalex.org/S77754710","display_name":"Journal of Saudi Chemical Society","issn_l":"1319-6103","issn":["1319-6103","2212-4640"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Saudi Chemical Society","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:8440450b58cc4e08a68e6223f0f679b4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8440450b58cc4e08a68e6223f0f679b4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Saudi Chemical Society, Vol 19, Iss 1, Pp 97-100 (2015)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jscs.2011.12.026","doi":"https://doi.org/10.1016/j.jscs.2011.12.026","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jscs.2011.12.026","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1319610312000026/pdf","source":{"id":"https://openalex.org/S77754710","display_name":"Journal of Saudi Chemical Society","issn_l":"1319-6103","issn":["1319-6103","2212-4640"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Saudi Chemical Society","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2061464673.pdf","grobid_xml":"https://content.openalex.org/works/W2061464673.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W225874882","https://openalex.org/W1587551779","https://openalex.org/W1928700421","https://openalex.org/W1974516740","https://openalex.org/W1989705993","https://openalex.org/W1997217890","https://openalex.org/W2001946037","https://openalex.org/W2002666693","https://openalex.org/W2006257291","https://openalex.org/W2010635450","https://openalex.org/W2019928365","https://openalex.org/W2024716555","https://openalex.org/W2025686120","https://openalex.org/W2026312885","https://openalex.org/W2031596649","https://openalex.org/W2064724317","https://openalex.org/W2074587681","https://openalex.org/W2082503951","https://openalex.org/W2091648971","https://openalex.org/W2144246240","https://openalex.org/W2328089547"],"related_works":["https://openalex.org/W6931682948","https://openalex.org/W4417101894","https://openalex.org/W2043302149","https://openalex.org/W4390715634","https://openalex.org/W4392878940","https://openalex.org/W2124986879","https://openalex.org/W3117210664","https://openalex.org/W3186636902","https://openalex.org/W2904175569","https://openalex.org/W2113064421"],"abstract_inverted_index":{"Chemical":[0],"composition":[1],"analysis":[2],"of":[3,10,17,31,64,77,105],"essential":[4],"oil":[5,34,78],"isolated":[6,33],"from":[7],"the":[8,15,32],"leaves":[9],"Ocimum":[11],"canum":[12],"Sims.":[13],"reported":[14],"presence":[16],"thirty":[18],"six":[19],"compounds.":[20],"The":[21],"major":[22],"compound":[23],"was":[24,79,111],"camphor":[25],"(39.77%).":[26],"In":[27],"vitro":[28],"antioxidant":[29],"activity":[30,41,76],"showed":[35],"dose":[36],"dependent":[37],"free":[38],"radical":[39],"scavenging":[40],"against":[42],"DPPH":[43],"(IC50":[44,103],"523.55":[45],"\u00b1":[46,53,59,68,94,98],"0.001":[47,60],"\u03bcg/mL)":[48,61,70,107],"and":[49,62,91,96,108],"hydroxyl":[50],"radicals":[51],"(491.12":[52],"0.002":[54,95],"\u03bcg/mL),":[55],"metal":[56],"chelating":[57],"(781.38":[58],"prevention":[63],"deoxyribose":[65],"degradation":[66],"(168.50":[67],"0.003":[69],"activities":[71],"were":[72],"also":[73],"calculated.":[74],"Antioxidant":[75],"less":[80],"observed":[81,112],"when":[82],"compared":[83],"with":[84],"positive":[85],"controls":[86],"such":[87],"as":[88],"ascorbic":[89],"acid":[90],"BHT":[92],"(12.49":[93],"30.14":[97],"0.005,":[99],"respectively).":[100],"Significant":[101],"cytotoxicity":[102],"value":[104],"60":[106],"DNA":[109],"fragmentation":[110],"in":[113],"breast":[114],"cancer":[115],"cells":[116],"(MCF-7).":[117]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}