{"id":"https://openalex.org/W2061343546","doi":"https://doi.org/10.5935/1678-9741.20150021","title":"Cardiopulmonary bypass: development of John Gibbon's heart-lung machine","display_name":"Cardiopulmonary bypass: development of John Gibbon's heart-lung machine","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2061343546","doi":"https://doi.org/10.5935/1678-9741.20150021","mag":"2061343546","pmid":"https://pubmed.ncbi.nlm.nih.gov/26107456","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4462970"},"language":"en","primary_location":{"id":"doi:10.5935/1678-9741.20150021","doi":"https://doi.org/10.5935/1678-9741.20150021","is_oa":true,"landing_page_url":"https://doi.org/10.5935/1678-9741.20150021","pdf_url":null,"source":{"id":"https://openalex.org/S4210172669","display_name":"Brazilian Journal of Cardiovascular Surgery","issn_l":"0102-7638","issn":["0102-7638","1678-9741"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312582","host_organization_name":"Brazilian Society of Cardiovascular Surgery","host_organization_lineage":["https://openalex.org/P4310312582"],"host_organization_lineage_names":["Brazilian Society of Cardiovascular Surgery"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Brasileira de Cirurgia Cardiovascular","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5935/1678-9741.20150021","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044489926","display_name":"Andr\u00e9ia Cristina Passaroni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andr\u00e9ia Cristina Passaroni","raw_affiliation_strings":["Botucatu, Botucatu, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Botucatu, Botucatu, SP, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057442338","display_name":"Marcos Augusto de Moraes Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcos Augusto de Moraes Silva","raw_affiliation_strings":["Department of Surgery and Orthopedics, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery and Orthopedics, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026398032","display_name":"Winston Bonetti Yoshida","orcid":"https://orcid.org/0000-0002-2921-3777","observed_orcids":["https://orcid.org/0000-0002-2921-3777"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Winston Bonetti Yoshida","raw_affiliation_strings":["Department of Surgery and Orthopedics, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brazil","Universidade Estadual Paulista, Botucatu, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery and Orthopedics, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brazil","institution_ids":["https://openalex.org/I879563668"]},{"raw_affiliation_string":"Universidade Estadual Paulista, Botucatu, Brazil","institution_ids":["https://openalex.org/I879563668"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5044489926"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.1436,"has_fulltext":false,"cited_by_count":97,"citation_normalized_percentile":{"value":0.97576383,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"30","issue":"2","first_page":"235","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12990","display_name":"Medical History and Innovations","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1202","display_name":"History"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiopulmonary-bypass","display_name":"cardiopulmonary bypass","score":1.0},{"id":"https://openalex.org/keywords/john-gibbon","display_name":"John Gibbon","score":0.8579999804496765},{"id":"https://openalex.org/keywords/heart-lung-machine","display_name":"heart-lung machine","score":0.9810000061988831},{"id":"https://openalex.org/keywords/extracorporeal-circulation","display_name":"extracorporeal circulation","score":0.9760000109672546},{"id":"https://openalex.org/keywords/history-of-cardiopulmonary-bypass","display_name":"history of cardiopulmonary bypass","score":0.8970000147819519},{"id":"https://openalex.org/keywords/hemolysis","display_name":"hemolysis","score":0.925000011920929},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5789999961853027},{"id":"https://openalex.org/keywords/multiple-organ-failure","display_name":"multiple organ failure","score":0.9929999709129333},{"id":"https://openalex.org/keywords/postoperative-care","display_name":"postoperative care","score":0.781000018119812},{"id":"https://openalex.org/keywords/cardiovascular-surgery","display_name":"cardiovascular surgery","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C2778881276","wikidata":"https://www.wikidata.org/wiki/Q552304","display_name":"Cardiopulmonary bypass","level":2,"score":0.9469591975212097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8749656677246094},{"id":"https://openalex.org/C2994232697","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal circulation","level":2,"score":0.8202695846557617},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5397513508796692},{"id":"https://openalex.org/C2779915274","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal","level":2,"score":0.4757542312145233},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4339140057563782},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2772738039493561},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.26144635677337646},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.206082284450531}],"mesh":[{"descriptor_ui":"D002315","descriptor_name":"Cardiopulmonary Bypass","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D002315","descriptor_name":"Cardiopulmonary Bypass","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D002315","descriptor_name":"Cardiopulmonary Bypass","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006355","descriptor_name":"Heart-Lung Machine","qualifier_ui":"Q000266","qualifier_name":"history","is_major_topic":false},{"descriptor_ui":"D006355","descriptor_name":"Heart-Lung Machine","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D006461","descriptor_name":"Hemolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010106","descriptor_name":"Oxygenators","qualifier_ui":"Q000266","qualifier_name":"history","is_major_topic":false},{"descriptor_ui":"D010106","descriptor_name":"Oxygenators","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D049672","descriptor_name":"History, 19th Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049673","descriptor_name":"History, 20th Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049674","descriptor_name":"History, 21st Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":12,"locations":[{"id":"doi:10.5935/1678-9741.20150021","doi":"https://doi.org/10.5935/1678-9741.20150021","is_oa":true,"landing_page_url":"https://doi.org/10.5935/1678-9741.20150021","pdf_url":null,"source":{"id":"https://openalex.org/S4210172669","display_name":"Brazilian Journal of Cardiovascular Surgery","issn_l":"0102-7638","issn":["0102-7638","1678-9741"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312582","host_organization_name":"Brazilian Society of Cardiovascular Surgery","host_organization_lineage":["https://openalex.org/P4310312582"],"host_organization_lineage_names":["Brazilian Society of Cardiovascular Surgery"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Brasileira de Cirurgia Cardiovascular","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3429945","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4462970","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4462970","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4462970","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rev Bras Cir Cardiovasc","raw_type":"Text"},{"id":"pmid:26107456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26107456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular","raw_type":"Historical Article"},{"id":"pmh:oai:scielo:S0102-76382015000200015","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382015000200015","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian Journal of Cardiovascular Surgery v.30 n.2 2015","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:acervodigital.unesp.br:11449/131085","doi":null,"is_oa":true,"landing_page_url":"http://acervodigital.unesp.br/handle/11449/131085","pdf_url":null,"source":{"id":"https://openalex.org/S4306400256","display_name":"Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115194","host_organization_name":"Funda\u00e7\u00e3o para o Desenvolvimento da UNESP","host_organization_lineage":["https://openalex.org/I4210115194"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"outro"},{"id":"pmh:oai:americanae.aecid.es:1790076","doi":null,"is_oa":true,"landing_page_url":"http://americanae.aecid.es/americanae/es/registros/registro.do?tipoRegistro=MTD&idBib=1790076","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UNESP","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2524479","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382015000200015","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brazilian Journal of Cardiovascular Surgery v.30 n.2 2015","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:800438ffcfe041eba6b1e275ac7cb690","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/800438ffcfe041eba6b1e275ac7cb690","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brazilian Journal of Cardiovascular Surgery, Vol 30, Iss 2, Pp 235-245 (2015)","raw_type":"article"},{"id":"pmh:oai:redalyc.org:398941897015","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=398941897015","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.2 Vol.30","raw_type":"art\u00edculo cient\u00edfico"},{"id":"pmh:oai:repositorio.unesp.br:11449/131085","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/131085","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNESP","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"mag:2310429653","doi":null,"is_oa":false,"landing_page_url":"https://www.scielo.br/pdf/rbccv/v30n2/0102-7638-rbccv-30-02-0235.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.5935/1678-9741.20150021","doi":"https://doi.org/10.5935/1678-9741.20150021","is_oa":true,"landing_page_url":"https://doi.org/10.5935/1678-9741.20150021","pdf_url":null,"source":{"id":"https://openalex.org/S4210172669","display_name":"Brazilian Journal of Cardiovascular Surgery","issn_l":"0102-7638","issn":["0102-7638","1678-9741"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312582","host_organization_name":"Brazilian Society of Cardiovascular Surgery","host_organization_lineage":["https://openalex.org/P4310312582"],"host_organization_lineage_names":["Brazilian Society of Cardiovascular Surgery"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Brasileira de Cirurgia Cardiovascular","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W17603250","https://openalex.org/W67368441","https://openalex.org/W168540395","https://openalex.org/W430176292","https://openalex.org/W563416080","https://openalex.org/W1558931992","https://openalex.org/W1559810451","https://openalex.org/W1578770791","https://openalex.org/W1607944370","https://openalex.org/W1814236892","https://openalex.org/W1942290192","https://openalex.org/W1972312145","https://openalex.org/W1975076015","https://openalex.org/W1982635616","https://openalex.org/W1983303312","https://openalex.org/W1997443963","https://openalex.org/W2009718675","https://openalex.org/W2017132882","https://openalex.org/W2020427481","https://openalex.org/W2037577655","https://openalex.org/W2039700114","https://openalex.org/W2046014127","https://openalex.org/W2048828250","https://openalex.org/W2049294945","https://openalex.org/W2049641829","https://openalex.org/W2067717418","https://openalex.org/W2077172355","https://openalex.org/W2077942407","https://openalex.org/W2088640690","https://openalex.org/W2106990979","https://openalex.org/W2120322195","https://openalex.org/W2126590246","https://openalex.org/W2130521645","https://openalex.org/W2163707370","https://openalex.org/W2164181990","https://openalex.org/W2171870191","https://openalex.org/W2254471350","https://openalex.org/W2264426589","https://openalex.org/W2268205969","https://openalex.org/W2328987305","https://openalex.org/W2329810325","https://openalex.org/W2398692485","https://openalex.org/W2402160550","https://openalex.org/W2409980818","https://openalex.org/W2411584991","https://openalex.org/W2411854796","https://openalex.org/W2412769925","https://openalex.org/W2414250214","https://openalex.org/W2414453696","https://openalex.org/W2427601073","https://openalex.org/W2461496402","https://openalex.org/W2463562921","https://openalex.org/W4236584840","https://openalex.org/W4253911253","https://openalex.org/W4254474046","https://openalex.org/W4396947496"],"related_works":["https://openalex.org/W2310429653","https://openalex.org/W2467806987","https://openalex.org/W3185810578","https://openalex.org/W4245856367","https://openalex.org/W3113426385","https://openalex.org/W2003271395","https://openalex.org/W4244932555","https://openalex.org/W208013563","https://openalex.org/W2054643656","https://openalex.org/W137800414"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"provide":[2],"a":[3],"brief":[4],"review":[5,14],"of":[6,9,15,21,45,58,67,99,121,128,147],"the":[7,16,19,32,56,79,87,95,114,125,145],"development":[8,20,98],"cardiopulmonary":[10,59,83,111,129],"bypass.":[11],"METHODS:":[12],"A":[13],"literature":[17],"on":[18],"extracorporeal":[22,46],"circulation":[23,47],"techniques,":[24],"their":[25,36,136],"essential":[26,52,141],"role":[27,53],"in":[28,54,81,110,113],"cardiovascular":[29],"surgery,":[30],"and":[31,40,93,132],"complications":[33,57],"associated":[34],"with":[35],"use,":[37],"including":[38],"hemolysis":[39],"inflammation.":[41],"RESULTS:":[42],"The":[43],"advancement":[44],"techniques":[48,131],"has":[49,107],"played":[50],"an":[51],"minimizing":[55],"bypass,":[60],"which":[61,82],"can":[62],"range":[63],"from":[64],"various":[65],"degrees":[66],"tissue":[68],"injury":[69],"to":[70,134],"multiple":[71],"organ":[72],"dysfunction":[73],"syndrome.":[74],"Investigators":[75],"have":[76],"long":[77],"researched":[78],"ways":[80],"bypass":[84,112,130],"may":[85],"insult":[86],"human":[88],"body.":[89],"Potential":[90],"solutions":[91],"arose":[92],"laid":[94],"groundwork":[96],"for":[97],"safer":[100],"postoperative":[101],"care":[102],"strategies.":[103],"CONCLUSION:":[104],"Steady":[105],"progress":[106],"been":[108],"made":[109],"decades":[115],"since":[116],"it":[117,138],"was":[118],"first":[119],"conceived":[120],"by":[122],"Gibbon.":[123],"Despite":[124],"constant":[126],"evolution":[127],"attempts":[133],"minimize":[135],"complications,":[137],"is":[139],"still":[140],"that":[142],"clinicians":[143],"respect":[144],"particularities":[146],"each":[148],"patient's":[149],"physiological":[150],"function.":[151]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":17},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}