{"id":"https://openalex.org/W2061208799","doi":"https://doi.org/10.1016/0022-4731(83)90349-7","title":"Comparison of corticosteroid binder IB with the \u03b1-chymotrypsin- and RNase-treated hepatic glucocorticoid receptors","display_name":"Comparison of corticosteroid binder IB with the \u03b1-chymotrypsin- and RNase-treated hepatic glucocorticoid receptors","publication_year":1983,"publication_date":"1983-12-01","ids":{"openalex":"https://openalex.org/W2061208799","doi":"https://doi.org/10.1016/0022-4731(83)90349-7","mag":"2061208799","pmid":"https://pubmed.ncbi.nlm.nih.gov/6672455"},"language":"en","primary_location":{"id":"doi:10.1016/0022-4731(83)90349-7","doi":"https://doi.org/10.1016/0022-4731(83)90349-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-4731(83)90349-7","pdf_url":null,"source":{"id":"https://openalex.org/S104308233","display_name":"Journal of Steroid Biochemistry","issn_l":"0022-4731","issn":["0022-4731","1878-2353"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320146","host_organization_name":"Pergamon Press","host_organization_lineage":["https://openalex.org/P4310320146"],"host_organization_lineage_names":["Pergamon Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Steroid Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Michael Mayer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Mayer","raw_affiliation_strings":["Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101825199","display_name":"Thomas J. Schmidt","orcid":"https://orcid.org/0000-0002-6792-9426","observed_orcids":["https://orcid.org/0000-0002-6792-9426"]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas J. Schmidt","raw_affiliation_strings":["Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012830083","display_name":"Andrea Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Miller","raw_affiliation_strings":["Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062814155","display_name":"Gerald Litwack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gerald Litwack","raw_affiliation_strings":["Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute and Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062814155"],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":null,"apc_paid":null,"fwci":1.3086,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.81036784,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"6","first_page":"1719","last_page":"1728"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-chymotrypsin","display_name":"alpha-chymotrypsin","score":0.7559999823570251},{"id":"https://openalex.org/keywords/ribonuclease","display_name":"ribonuclease","score":0.8069999814033508},{"id":"https://openalex.org/keywords/proteolytic-cleavage","display_name":"proteolytic cleavage","score":0.8069999814033508},{"id":"https://openalex.org/keywords/dna-binding","display_name":"DNA binding","score":0.6420000195503235},{"id":"https://openalex.org/keywords/receptor-activation","display_name":"receptor activation","score":0.5600000023841858},{"id":"https://openalex.org/keywords/molybdate","display_name":"molybdate","score":0.7870000004768372},{"id":"https://openalex.org/keywords/triamcinolone-acetonide","display_name":"triamcinolone acetonide","score":0.8270000219345093},{"id":"https://openalex.org/keywords/thermal-activation","display_name":"thermal activation","score":0.46799999475479126},{"id":"https://openalex.org/keywords/receptor-fragments","display_name":"receptor fragments","score":0.37700000405311584},{"id":"https://openalex.org/keywords/liver-cytosol","display_name":"liver cytosol","score":0.7390000224113464},{"id":"https://openalex.org/keywords/kidney-cytosol","display_name":"kidney cytosol","score":0.828000009059906}],"concepts":[{"id":"https://openalex.org/C2778401398","wikidata":"https://www.wikidata.org/wiki/Q383836","display_name":"Chymotrypsin","level":4,"score":0.8523823022842407},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5581757426261902},{"id":"https://openalex.org/C59493245","wikidata":"https://www.wikidata.org/wiki/Q14877410","display_name":"Glucocorticoid receptor","level":3,"score":0.538180947303772},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5088387131690979},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.5040730237960815},{"id":"https://openalex.org/C187428577","wikidata":"https://www.wikidata.org/wiki/Q898396","display_name":"Ionic strength","level":3,"score":0.45056501030921936},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34144848585128784},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3381883502006531},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.18963903188705444},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1468091905117035},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002627","descriptor_name":"Chemistry, Physical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011987","descriptor_name":"Receptors, Steroid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012260","descriptor_name":"Ribonucleases","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014222","descriptor_name":"Triamcinolone Acetonide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0022-4731(83)90349-7","doi":"https://doi.org/10.1016/0022-4731(83)90349-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-4731(83)90349-7","pdf_url":null,"source":{"id":"https://openalex.org/S104308233","display_name":"Journal of Steroid Biochemistry","issn_l":"0022-4731","issn":["0022-4731","1878-2353"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320146","host_organization_name":"Pergamon Press","host_organization_lineage":["https://openalex.org/P4310320146"],"host_organization_lineage_names":["Pergamon Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Steroid Biochemistry","raw_type":"journal-article"},{"id":"pmid:6672455","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6672455","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of steroid biochemistry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1530691713","https://openalex.org/W1539647160","https://openalex.org/W1568326379","https://openalex.org/W1574229173","https://openalex.org/W1896307881","https://openalex.org/W1981873462","https://openalex.org/W1989054182","https://openalex.org/W2014139892","https://openalex.org/W2015663161","https://openalex.org/W2018531293","https://openalex.org/W2018632980","https://openalex.org/W2022999461","https://openalex.org/W2023652595","https://openalex.org/W2023693348","https://openalex.org/W2024098392","https://openalex.org/W2028053733","https://openalex.org/W2050586961","https://openalex.org/W2061146527","https://openalex.org/W2062557765","https://openalex.org/W2090691291","https://openalex.org/W2119826308","https://openalex.org/W2270533120","https://openalex.org/W2342073136","https://openalex.org/W2419134914","https://openalex.org/W4230614103","https://openalex.org/W6677898342"],"related_works":["https://openalex.org/W2061146527","https://openalex.org/W1570892620","https://openalex.org/W2040790550","https://openalex.org/W4245143772","https://openalex.org/W2119826308","https://openalex.org/W2077816883","https://openalex.org/W2074076851","https://openalex.org/W2082152860","https://openalex.org/W1493116705","https://openalex.org/W2002100511"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}