{"id":"https://openalex.org/W2060733217","doi":"https://doi.org/10.1016/0301-4622(90)88021-j","title":"High-performance liquid chromatography of globin chains in the identification of human globin gene abnormalities.","display_name":"High-performance liquid chromatography of globin chains in the identification of human globin gene abnormalities.","publication_year":1990,"publication_date":"1990-08-01","ids":{"openalex":"https://openalex.org/W2060733217","doi":"https://doi.org/10.1016/0301-4622(90)88021-j","mag":"2060733217","pmid":"https://pubmed.ncbi.nlm.nih.gov/2285783"},"language":"en","primary_location":{"id":"doi:10.1016/0301-4622(90)88021-j","doi":"https://doi.org/10.1016/0301-4622(90)88021-j","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0301-4622(90)88021-j","pdf_url":null,"source":{"id":"https://openalex.org/S63395545","display_name":"Biophysical Chemistry","issn_l":"0301-4622","issn":["0301-4622","1873-4200"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086199839","display_name":"Bruno Masala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159650629","display_name":"University of Sassari","ror":"https://ror.org/01bnjbv91","country_code":"IT","type":"education","lineage":["https://openalex.org/I159650629"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Bruno Masala","raw_affiliation_strings":["Istituto di Fisiologia Generale e Chimica Biologica, Universit\u00e0 di Sassari, Italy","Istituto di Fisiologia Generale e Chimica Biologica, Universita di Sassari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Fisiologia Generale e Chimica Biologica, Universit\u00e0 di Sassari, Italy","institution_ids":["https://openalex.org/I159650629"]},{"raw_affiliation_string":"Istituto di Fisiologia Generale e Chimica Biologica, Universita di Sassari, Italy","institution_ids":["https://openalex.org/I159650629"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009247012","display_name":"Laura Manca","orcid":"https://orcid.org/0000-0002-2076-3510","observed_orcids":["https://orcid.org/0000-0002-2076-3510"]},"institutions":[{"id":"https://openalex.org/I159650629","display_name":"University of Sassari","ror":"https://ror.org/01bnjbv91","country_code":"IT","type":"education","lineage":["https://openalex.org/I159650629"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Manca","raw_affiliation_strings":["Istituto di Fisiologia Generale e Chimica Biologica, Universit\u00e0 di Sassari, Via Muroni 25, 07100 Sassari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Fisiologia Generale e Chimica Biologica, Universit\u00e0 di Sassari, Via Muroni 25, 07100 Sassari, Italy","institution_ids":["https://openalex.org/I159650629"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086199839"],"corresponding_institution_ids":["https://openalex.org/I159650629"],"apc_list":{"value":3720,"currency":"USD","value_usd":3720},"apc_paid":null,"fwci":1.8385,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.85925488,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"37","issue":"1-3","first_page":"225","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/globin-chains","display_name":"globin chains","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hemoglobinopathies","display_name":"hemoglobinopathies","score":0.7390000224113464},{"id":"https://openalex.org/keywords/hemoglobin-variants","display_name":"hemoglobin variants","score":0.9330000281333923},{"id":"https://openalex.org/keywords/thalassemia","display_name":"thalassemia","score":0.8849999904632568},{"id":"https://openalex.org/keywords/sardinian-population","display_name":"Sardinian population","score":0.8849999904632568},{"id":"https://openalex.org/keywords/reversed-phase-hplc","display_name":"reversed-phase HPLC","score":0.6549999713897705}],"concepts":[{"id":"https://openalex.org/C125996951","wikidata":"https://www.wikidata.org/wiki/Q412234","display_name":"Globin","level":3,"score":0.7631015777587891},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7452560663223267},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6349446177482605},{"id":"https://openalex.org/C2779668550","wikidata":"https://www.wikidata.org/wiki/Q1642147","display_name":"Hemoglobinopathy","level":3,"score":0.543358564376831},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5425958633422852},{"id":"https://openalex.org/C2777799968","wikidata":"https://www.wikidata.org/wiki/Q185137","display_name":"Thalassemia","level":2,"score":0.45732581615448},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.44466015696525574},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.44280004501342773},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3333989381790161},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2757123112678528},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.256253182888031},{"id":"https://openalex.org/C2776175824","wikidata":"https://www.wikidata.org/wiki/Q1145668","display_name":"Hemolytic anemia","level":2,"score":0.1492452323436737},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1172666847705841},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.08057522773742676},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002872","descriptor_name":"Chromosome Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005914","descriptor_name":"Globins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005914","descriptor_name":"Globins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D006441","descriptor_name":"Hemoglobin A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015321","descriptor_name":"Gene Rearrangement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/0301-4622(90)88021-j","doi":"https://doi.org/10.1016/0301-4622(90)88021-j","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0301-4622(90)88021-j","pdf_url":null,"source":{"id":"https://openalex.org/S63395545","display_name":"Biophysical Chemistry","issn_l":"0301-4622","issn":["0301-4622","1873-4200"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Chemistry","raw_type":"journal-article"},{"id":"pmid:2285783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2285783","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniss.it:11388/146315","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11388/146315","pdf_url":null,"source":{"id":"https://openalex.org/S4306401147","display_name":"UnissResearch (Universit\u00e0 degli Studi di Sassari)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I159650629","host_organization_name":"University of Sassari","host_organization_lineage":["https://openalex.org/I159650629"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.504800021648407,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1485437772","https://openalex.org/W1967647423","https://openalex.org/W1968253478","https://openalex.org/W1971986867","https://openalex.org/W1984349466","https://openalex.org/W1984560477","https://openalex.org/W1985926923","https://openalex.org/W1991670883","https://openalex.org/W1999285816","https://openalex.org/W1999404790","https://openalex.org/W2000934575","https://openalex.org/W2006371801","https://openalex.org/W2006672992","https://openalex.org/W2012901225","https://openalex.org/W2014276704","https://openalex.org/W2015391188","https://openalex.org/W2017321326","https://openalex.org/W2021935029","https://openalex.org/W2029073209","https://openalex.org/W2039427692","https://openalex.org/W2040351665","https://openalex.org/W2042097062","https://openalex.org/W2046941639","https://openalex.org/W2057850339","https://openalex.org/W2061034141","https://openalex.org/W2063342627","https://openalex.org/W2065299675","https://openalex.org/W2083877457","https://openalex.org/W2086152942","https://openalex.org/W2087299117","https://openalex.org/W2087957661","https://openalex.org/W2090722439","https://openalex.org/W2093935900","https://openalex.org/W2102606458","https://openalex.org/W2163253507","https://openalex.org/W2164746192","https://openalex.org/W2329436403","https://openalex.org/W2413266486","https://openalex.org/W2418882215"],"related_works":["https://openalex.org/W2112513056","https://openalex.org/W2419589528","https://openalex.org/W2040421478","https://openalex.org/W1984560477","https://openalex.org/W2061034141","https://openalex.org/W7043815995","https://openalex.org/W1915753797","https://openalex.org/W2012901225","https://openalex.org/W2101742876","https://openalex.org/W2020306029"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}