{"id":"https://openalex.org/W2060412271","doi":"https://doi.org/10.1016/s0969-2126(96)00071-8","title":"Reading between the lines: SH3 recognition of an intact protein","display_name":"Reading between the lines: SH3 recognition of an intact protein","publication_year":1996,"publication_date":"1996-06-01","ids":{"openalex":"https://openalex.org/W2060412271","doi":"https://doi.org/10.1016/s0969-2126(96)00071-8","mag":"2060412271","pmid":"https://pubmed.ncbi.nlm.nih.gov/8805558"},"language":"en","primary_location":{"id":"doi:10.1016/s0969-2126(96)00071-8","doi":"https://doi.org/10.1016/s0969-2126(96)00071-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0969-2126(96)00071-8","pdf_url":"http://www.cell.com/article/S0969212696000718/pdf","source":{"id":"https://openalex.org/S7112016","display_name":"Structure","issn_l":"0969-2126","issn":["0969-2126","1878-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.cell.com/article/S0969212696000718/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006257775","display_name":"Wendell A. Lim","orcid":"https://orcid.org/0000-0003-4052-8056","observed_orcids":["https://orcid.org/0000-0003-4052-8056"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wendell A Lim","raw_affiliation_strings":["Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520-8114, USA","Wendell A Lim, Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520-114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520-8114, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Wendell A Lim, Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520-114, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5006257775"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":{"value":9350,"currency":"USD","value_usd":9350},"apc_paid":{"value":9350,"currency":"USD","value_usd":9350},"fwci":0.8836,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.72483073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"4","issue":"6","first_page":"657","last_page":"659"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.8848000168800354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.8848000168800354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.05480000004172325,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sh3-domain","display_name":"SH3 domain","score":0.9879999756813049},{"id":"https://openalex.org/keywords/nef-protein","display_name":"Nef protein","score":0.8489999771118164},{"id":"https://openalex.org/keywords/proline-rich-motif","display_name":"proline-rich motif","score":0.7020000219345093},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.871999979019165},{"id":"https://openalex.org/keywords/protein-recognition","display_name":"protein recognition","score":0.453000009059906},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C196347352","wikidata":"https://www.wikidata.org/wiki/Q24771787","display_name":"SH3 domain","level":4,"score":0.8986409902572632},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6025639176368713},{"id":"https://openalex.org/C554936623","wikidata":"https://www.wikidata.org/wiki/Q199657","display_name":"Reading (process)","level":2,"score":0.5099400281906128},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5072731375694275},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4208143651485443},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41477522253990173},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30434489250183105},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.25302213430404663},{"id":"https://openalex.org/C108636557","wikidata":"https://www.wikidata.org/wiki/Q21109354","display_name":"Proto-oncogene tyrosine-protein kinase Src","level":3,"score":0.20424363017082214},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.13235226273536682},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.10055661201477051},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.07851460576057434},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011505","descriptor_name":"Protein-Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011505","descriptor_name":"Protein-Tyrosine Kinases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015693","descriptor_name":"Gene Products, nef","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015693","descriptor_name":"Gene Products, nef","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D017124","descriptor_name":"Conserved Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018909","descriptor_name":"src Homology Domains","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051572","descriptor_name":"Proto-Oncogene Proteins c-hck","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0969-2126(96)00071-8","doi":"https://doi.org/10.1016/s0969-2126(96)00071-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0969-2126(96)00071-8","pdf_url":"http://www.cell.com/article/S0969212696000718/pdf","source":{"id":"https://openalex.org/S7112016","display_name":"Structure","issn_l":"0969-2126","issn":["0969-2126","1878-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure","raw_type":"journal-article"},{"id":"pmid:8805558","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8805558","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure (London, England : 1993)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0969-2126(96)00071-8","doi":"https://doi.org/10.1016/s0969-2126(96)00071-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0969-2126(96)00071-8","pdf_url":"http://www.cell.com/article/S0969212696000718/pdf","source":{"id":"https://openalex.org/S7112016","display_name":"Structure","issn_l":"0969-2126","issn":["0969-2126","1878-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2060412271.pdf"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W62276193","https://openalex.org/W77973074","https://openalex.org/W1522400918","https://openalex.org/W1923801572","https://openalex.org/W1967448808","https://openalex.org/W1967582433","https://openalex.org/W1969403795","https://openalex.org/W1971377120","https://openalex.org/W1974951679","https://openalex.org/W1982186905","https://openalex.org/W1984780483","https://openalex.org/W1990516841","https://openalex.org/W1994240328","https://openalex.org/W1995303015","https://openalex.org/W1999133681","https://openalex.org/W2030608812","https://openalex.org/W2030884611","https://openalex.org/W2056189051","https://openalex.org/W2065033398","https://openalex.org/W2065663262","https://openalex.org/W2076058809","https://openalex.org/W2098552577","https://openalex.org/W2106819022","https://openalex.org/W2159220993","https://openalex.org/W6674852347"],"related_works":["https://openalex.org/W125596170","https://openalex.org/W2053655942","https://openalex.org/W88215431","https://openalex.org/W2150545125","https://openalex.org/W2610523882","https://openalex.org/W1983934308","https://openalex.org/W2158133029","https://openalex.org/W1960795564","https://openalex.org/W7216800640","https://openalex.org/W2757219308"],"abstract_inverted_index":{"The":[0],"structure":[1],"of":[2,27],"Nef-SH3":[3],"domain":[4,10],"complex":[5],"reveals":[6],"how":[7],"an":[8],"SH3":[9],"can":[11],"more":[12],"effectively":[13],"'read'":[14],"its":[15],"linear":[16],"proline-rich":[17],"recognition":[18],"element":[19],"when":[20],"it":[21],"is":[22],"presented":[23],"within":[24],"the":[25],"context":[26],"a":[28],"folded":[29],"protein.":[30]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}