{"id":"https://openalex.org/W2060107334","doi":"https://doi.org/10.1016/j.placenta.2014.09.005","title":"Different expression of placental pyruvate kinase in normal, preeclamptic and intrauterine growth restriction pregnancies","display_name":"Different expression of placental pyruvate kinase in normal, preeclamptic and intrauterine growth restriction pregnancies","publication_year":2014,"publication_date":"2014-09-16","ids":{"openalex":"https://openalex.org/W2060107334","doi":"https://doi.org/10.1016/j.placenta.2014.09.005","mag":"2060107334","pmid":"https://pubmed.ncbi.nlm.nih.gov/25260566"},"language":"en","primary_location":{"id":"doi:10.1016/j.placenta.2014.09.005","doi":"https://doi.org/10.1016/j.placenta.2014.09.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.placenta.2014.09.005","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111056190","display_name":"Brennan Bahr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.L. Bahr","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003166666","display_name":"Matthew Dean Price","orcid":"https://orcid.org/0000-0003-4837-3861","observed_orcids":["https://orcid.org/0000-0003-4837-3861"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.D. Price","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080717984","display_name":"Daniel Merrill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Merrill","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C. Mejia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Mejia","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007614973","display_name":"Lindsay Larson Call","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Call","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037979147","display_name":"David J. Bearss","orcid":"https://orcid.org/0000-0003-4940-9942","observed_orcids":["https://orcid.org/0000-0003-4940-9942"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Bearss","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011257603","display_name":"Juan Alberto Arroyo","orcid":"https://orcid.org/0000-0002-8818-8786","observed_orcids":["https://orcid.org/0000-0002-8818-8786"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. Arroyo","raw_affiliation_strings":["Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA. Electronic address: jarroyo@byu.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT, USA. Electronic address: jarroyo@byu.edu","institution_ids":["https://openalex.org/I100005738"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5011257603"],"corresponding_institution_ids":["https://openalex.org/I100005738"],"apc_list":{"value":3720,"currency":"USD","value_usd":3720},"apc_paid":null,"fwci":4.7503,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.94672878,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"35","issue":"11","first_page":"883","last_page":"890"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9359999895095825},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":1.0},{"id":"https://openalex.org/keywords/pkm2","display_name":"PKM2","score":0.9539999961853027},{"id":"https://openalex.org/keywords/placental-metabolism","display_name":"placental metabolism","score":0.7480000257492065},{"id":"https://openalex.org/keywords/erk1-2-phosphorylation","display_name":"ERK1/2 phosphorylation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/beta-catenin","display_name":"\u03b2-catenin","score":0.9940000176429749},{"id":"https://openalex.org/keywords/lactate-dehydrogenase","display_name":"lactate dehydrogenase","score":0.9819999933242798}],"concepts":[{"id":"https://openalex.org/C10730799","wikidata":"https://www.wikidata.org/wiki/Q18030568","display_name":"PKM2","level":5,"score":0.8767501711845398},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.7719813585281372},{"id":"https://openalex.org/C2777218350","wikidata":"https://www.wikidata.org/wiki/Q61335","display_name":"Preeclampsia","level":3,"score":0.7674261331558228},{"id":"https://openalex.org/C2778780700","wikidata":"https://www.wikidata.org/wiki/Q1671598","display_name":"Intrauterine growth restriction","level":4,"score":0.7164195775985718},{"id":"https://openalex.org/C2780854706","wikidata":"https://www.wikidata.org/wiki/Q900970","display_name":"Pyruvate kinase","level":4,"score":0.6972313523292542},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.6174743175506592},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.5622896552085876},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4250914752483368},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4232000708580017},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3926119804382324},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3799915909767151},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.3472655415534973},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3424641788005829},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.19485312700271606},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.15622428059577942},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09527617692947388},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06684207916259766},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000097810","descriptor_name":"Thyroid Hormone-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005317","descriptor_name":"Fetal Growth Retardation","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011770","descriptor_name":"Pyruvate Kinase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045022","descriptor_name":"Lactate Dehydrogenases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D048049","descriptor_name":"Extracellular Signal-Regulated MAP Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051176","descriptor_name":"beta Catenin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.placenta.2014.09.005","doi":"https://doi.org/10.1016/j.placenta.2014.09.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.placenta.2014.09.005","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},{"id":"pmid:25260566","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25260566","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G5742201421","display_name":null,"funder_award_id":"7R00HD055054-06","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G8594892516","display_name":null,"funder_award_id":"R00 HD055054","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G8660619816","display_name":"Apoptosis in an Ovine Model of Intrauterine Growth Restriction  (IUGR)","funder_award_id":"5r00hd055054-07","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W52275396","https://openalex.org/W1849560193","https://openalex.org/W1950131161","https://openalex.org/W1967832563","https://openalex.org/W1969836970","https://openalex.org/W1974169241","https://openalex.org/W1976440060","https://openalex.org/W1982503668","https://openalex.org/W1991137465","https://openalex.org/W1995444593","https://openalex.org/W2011037246","https://openalex.org/W2011435516","https://openalex.org/W2012895630","https://openalex.org/W2015207840","https://openalex.org/W2022101765","https://openalex.org/W2022431559","https://openalex.org/W2025267820","https://openalex.org/W2025499382","https://openalex.org/W2026894999","https://openalex.org/W2028397040","https://openalex.org/W2028897202","https://openalex.org/W2029255902","https://openalex.org/W2029285860","https://openalex.org/W2032226016","https://openalex.org/W2036540909","https://openalex.org/W2040266344","https://openalex.org/W2042498172","https://openalex.org/W2042706243","https://openalex.org/W2052072405","https://openalex.org/W2059463168","https://openalex.org/W2061865477","https://openalex.org/W2063078815","https://openalex.org/W2066969376","https://openalex.org/W2072451938","https://openalex.org/W2072756039","https://openalex.org/W2074864603","https://openalex.org/W2077254429","https://openalex.org/W2077680088","https://openalex.org/W2079467146","https://openalex.org/W2082365381","https://openalex.org/W2082499845","https://openalex.org/W2084022545","https://openalex.org/W2084430322","https://openalex.org/W2084888282","https://openalex.org/W2095576458","https://openalex.org/W2096601431","https://openalex.org/W2097259163","https://openalex.org/W2100260504","https://openalex.org/W2101047730","https://openalex.org/W2106204137","https://openalex.org/W2113877914","https://openalex.org/W2122101214","https://openalex.org/W2130219349","https://openalex.org/W2134847995","https://openalex.org/W2150950268","https://openalex.org/W2160209138","https://openalex.org/W2162059942","https://openalex.org/W2165414304","https://openalex.org/W2262134087","https://openalex.org/W2313220264","https://openalex.org/W2423710301","https://openalex.org/W2592835581","https://openalex.org/W4206893673","https://openalex.org/W6675242268","https://openalex.org/W6679604149"],"related_works":["https://openalex.org/W1451010875","https://openalex.org/W7027859778","https://openalex.org/W7099827612","https://openalex.org/W2095770086","https://openalex.org/W2410101816","https://openalex.org/W7151003298","https://openalex.org/W7211873394","https://openalex.org/W4398165392","https://openalex.org/W2395061702","https://openalex.org/W2018631858"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}