{"id":"https://openalex.org/W2059966974","doi":"https://doi.org/10.1111/jne.12160","title":"Tyrosine Hydroxylase in the Olfactory System, Forebrain and Pituitary of the Indian Major Carp, C irrhinus cirrhosus: Organisation and Interaction with Neuropeptide Y in the Preoptic Area","display_name":"Tyrosine Hydroxylase in the Olfactory System, Forebrain and Pituitary of the Indian Major Carp, C irrhinus cirrhosus: Organisation and Interaction with Neuropeptide Y in the Preoptic Area","publication_year":2014,"publication_date":"2014-04-19","ids":{"openalex":"https://openalex.org/W2059966974","doi":"https://doi.org/10.1111/jne.12160","mag":"2059966974","pmid":"https://pubmed.ncbi.nlm.nih.gov/24750502"},"language":"en","primary_location":{"id":"doi:10.1111/jne.12160","doi":"https://doi.org/10.1111/jne.12160","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jne.12160","pdf_url":null,"source":{"id":"https://openalex.org/S100175869","display_name":"Journal of Neuroendocrinology","issn_l":"0953-8194","issn":["0953-8194","1365-2826"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroendocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053395641","display_name":"Santosh Kumar","orcid":"https://orcid.org/0000-0002-9861-1090","observed_orcids":["https://orcid.org/0000-0002-9861-1090"]},"institutions":[{"id":"https://openalex.org/I163389970","display_name":"National Institute of Science Education and Research","ror":"https://ror.org/02r2k1c68","country_code":"IN","type":"education","lineage":["https://openalex.org/I163389970","https://openalex.org/I200207707"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S. Kumar","raw_affiliation_strings":["School of Biological Sciences, National Institute of Science Education and Research (NISER) , Bhubaneswar, Odisha , India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, National Institute of Science Education and Research (NISER) , Bhubaneswar, Odisha , India","institution_ids":["https://openalex.org/I163389970"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029601006","display_name":"Uday Singh","orcid":"https://orcid.org/0000-0002-5747-8369","observed_orcids":["https://orcid.org/0000-0002-5747-8369"]},"institutions":[{"id":"https://openalex.org/I163389970","display_name":"National Institute of Science Education and Research","ror":"https://ror.org/02r2k1c68","country_code":"IN","type":"education","lineage":["https://openalex.org/I163389970","https://openalex.org/I200207707"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"U. Singh","raw_affiliation_strings":["School of Biological Sciences National Institute of Science Education and Research (NISER) Bhubaneswar Odisha India","National Institute of Science Education and Research (NISER) School of Biological Sciences Bhubaneswar Odisha India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences National Institute of Science Education and Research (NISER) Bhubaneswar Odisha India","institution_ids":["https://openalex.org/I163389970"]},{"raw_affiliation_string":"National Institute of Science Education and Research (NISER) School of Biological Sciences Bhubaneswar Odisha India","institution_ids":["https://openalex.org/I163389970"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106035491","display_name":"Subhash G. Saha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163389970","display_name":"National Institute of Science Education and Research","ror":"https://ror.org/02r2k1c68","country_code":"IN","type":"education","lineage":["https://openalex.org/I163389970","https://openalex.org/I200207707"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S. Saha","raw_affiliation_strings":["School of Biological Sciences National Institute of Science Education and Research (NISER) Bhubaneswar Odisha India","National Institute of Science Education and Research (NISER) School of Biological Sciences Bhubaneswar Odisha India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences National Institute of Science Education and Research (NISER) Bhubaneswar Odisha India","institution_ids":["https://openalex.org/I163389970"]},{"raw_affiliation_string":"National Institute of Science Education and Research (NISER) School of Biological Sciences Bhubaneswar Odisha India","institution_ids":["https://openalex.org/I163389970"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052368696","display_name":"Praful S. Singru","orcid":"https://orcid.org/0000-0002-3958-0204","observed_orcids":["https://orcid.org/0000-0002-3958-0204"]},"institutions":[{"id":"https://openalex.org/I163389970","display_name":"National Institute of Science Education and Research","ror":"https://ror.org/02r2k1c68","country_code":"IN","type":"education","lineage":["https://openalex.org/I163389970","https://openalex.org/I200207707"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"P. S. Singru","raw_affiliation_strings":["School of Biological Sciences National Institute of Science Education and Research (NISER) Bhubaneswar Odisha India","National Institute of Science Education and Research (NISER) School of Biological Sciences Bhubaneswar Odisha India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences National Institute of Science Education and Research (NISER) Bhubaneswar Odisha India","institution_ids":["https://openalex.org/I163389970"]},{"raw_affiliation_string":"National Institute of Science Education and Research (NISER) School of Biological Sciences Bhubaneswar Odisha India","institution_ids":["https://openalex.org/I163389970"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5052368696"],"corresponding_institution_ids":["https://openalex.org/I163389970"],"apc_list":{"value":4550,"currency":"USD","value_usd":4550},"apc_paid":null,"fwci":2.1604,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.8403534,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"26","issue":"6","first_page":"400","last_page":"411"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tyrosine-hydroxylase","display_name":"tyrosine hydroxylase","score":0.996999979019165},{"id":"https://openalex.org/keywords/neuropeptide-y","display_name":"neuropeptide Y","score":0.9369999766349792},{"id":"https://openalex.org/keywords/preoptic-area","display_name":"preoptic area","score":0.8100000023841858},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.6740000247955322},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.6850000023841858},{"id":"https://openalex.org/keywords/gonadotropin-releasing-hormone","display_name":"gonadotropin-releasing hormone","score":0.9279999732971191},{"id":"https://openalex.org/keywords/npy-y2-receptor","display_name":"NPY Y2 receptor","score":0.8320000171661377},{"id":"https://openalex.org/keywords/npy-y1-receptor","display_name":"NPY Y1 receptor","score":0.7870000004768372},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.7149999737739563},{"id":"https://openalex.org/keywords/indian-major-carps","display_name":"Indian major carps","score":0.5910000205039978},{"id":"https://openalex.org/keywords/cirrhinus-cirrhosus","display_name":"Cirrhinus cirrhosus","score":0.9409999847412109}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8290902376174927},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7988812923431396},{"id":"https://openalex.org/C93984277","wikidata":"https://www.wikidata.org/wiki/Q24782073","display_name":"Neuropeptide Y receptor","level":4,"score":0.6732982397079468},{"id":"https://openalex.org/C2780496858","wikidata":"https://www.wikidata.org/wiki/Q644945","display_name":"Olfactory bulb","level":3,"score":0.6663548946380615},{"id":"https://openalex.org/C2776451244","wikidata":"https://www.wikidata.org/wiki/Q7240592","display_name":"Preoptic area","level":3,"score":0.6412960290908813},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.607446014881134},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.5827394127845764},{"id":"https://openalex.org/C159167319","wikidata":"https://www.wikidata.org/wiki/Q420766","display_name":"Tyrosine hydroxylase","level":3,"score":0.5733660459518433},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.5223292708396912},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.44740796089172363},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.3771008253097534},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.29333963990211487},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2323489487171173},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002347","descriptor_name":"Carps","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009478","descriptor_name":"Neuropeptide Y","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009830","descriptor_name":"Olfactory Bulb","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D010902","descriptor_name":"Pituitary Gland","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D011301","descriptor_name":"Preoptic Area","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013687","descriptor_name":"Telencephalon","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D014446","descriptor_name":"Tyrosine 3-Monooxygenase","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/jne.12160","doi":"https://doi.org/10.1111/jne.12160","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jne.12160","pdf_url":null,"source":{"id":"https://openalex.org/S100175869","display_name":"Journal of Neuroendocrinology","issn_l":"0953-8194","issn":["0953-8194","1365-2826"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroendocrinology","raw_type":"journal-article"},{"id":"pmid:24750502","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24750502","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroendocrinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.46810001134872437}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W25019130","https://openalex.org/W257124532","https://openalex.org/W1963624444","https://openalex.org/W1965279243","https://openalex.org/W1966841534","https://openalex.org/W1975298284","https://openalex.org/W1976640392","https://openalex.org/W1977390628","https://openalex.org/W1982192891","https://openalex.org/W1982239650","https://openalex.org/W1983935092","https://openalex.org/W1986748649","https://openalex.org/W1993697642","https://openalex.org/W1995093232","https://openalex.org/W1997346770","https://openalex.org/W1998398867","https://openalex.org/W2002941555","https://openalex.org/W2010282258","https://openalex.org/W2012567893","https://openalex.org/W2016622707","https://openalex.org/W2027092340","https://openalex.org/W2027397223","https://openalex.org/W2032673126","https://openalex.org/W2032810164","https://openalex.org/W2034805930","https://openalex.org/W2037657330","https://openalex.org/W2041135153","https://openalex.org/W2041923922","https://openalex.org/W2042626752","https://openalex.org/W2043965189","https://openalex.org/W2045033085","https://openalex.org/W2048223993","https://openalex.org/W2051549245","https://openalex.org/W2058205882","https://openalex.org/W2058306762","https://openalex.org/W2059163518","https://openalex.org/W2059828897","https://openalex.org/W2081941747","https://openalex.org/W2082899374","https://openalex.org/W2083014754","https://openalex.org/W2088942059","https://openalex.org/W2090919767","https://openalex.org/W2094594974","https://openalex.org/W2095184438","https://openalex.org/W2124682039","https://openalex.org/W2132184741","https://openalex.org/W2138469297","https://openalex.org/W2140850665","https://openalex.org/W2145902084","https://openalex.org/W2156628682","https://openalex.org/W2160277145","https://openalex.org/W2164098477","https://openalex.org/W2165988674","https://openalex.org/W2317857438","https://openalex.org/W2323069154","https://openalex.org/W2397238314","https://openalex.org/W2412751642","https://openalex.org/W2417458566","https://openalex.org/W2475100267","https://openalex.org/W3215230027","https://openalex.org/W3217656501"],"related_works":["https://openalex.org/W2018462202","https://openalex.org/W1994914312","https://openalex.org/W2132184741","https://openalex.org/W2547198240","https://openalex.org/W1995093232","https://openalex.org/W2059828897","https://openalex.org/W2120685788","https://openalex.org/W2014047855","https://openalex.org/W4243055179","https://openalex.org/W2049051839"],"abstract_inverted_index":{"Dopamine":[0],"(DA)":[1],"inhibits,":[2],"whereas":[3],"gonadotrophin-releasing":[4],"hormone":[5],"(GnRH)":[6],"stimulates,":[7],"luteinisiing":[8],"(LH)":[9],"cells":[10,107,110,119,275],"in":[11,22,62,81,114,120,155,204,224,231,233,237,261,286,293,300],"the":[12,23,30,46,63,82,96,99,115,132,134,161,176,270,273,294,301],"pituitary":[13,162],"of":[14,33,45,60,65,98,111,152,191,272,279,297],"some":[15],"but":[16,73],"not":[17,71,240],"all":[18],"teleosts.":[19,302],"A":[20],"reduction":[21,230],"hypophysiotropic":[24,66],"dopaminergic":[25],"tone":[26],"is":[27,70,75],"necessary":[28],"for":[29,178],"stimulatory":[31],"effect":[32],"GnRH":[34],"on":[35],"LH":[36,52,168,298],"cells.":[37,169,197],"Neuropeptide":[38,251],"Y":[39,252],"(NPY)":[40],"has":[41],"emerged":[42],"as":[43],"one":[44],"potent,":[47],"endogenous":[48],"agent":[49],"that":[50],"modulates":[51],"secretion":[53,299],"directly":[54],"or":[55],"indirectly":[56],"via":[57,263],"GnRH.":[58],"Involvement":[59],"NPY":[61,182,192,209,217,221,243,266,282],"regulation":[64,296],"DA":[67,85,184,280],"neurones,":[68,86],"however,":[69],"known,":[72],"there":[74],"good":[76],"evidence":[77],"suggesting":[78],"an":[79],"interaction":[80,180,285],"mammalian":[83],"hypothalamus.":[84],"identified":[87],"by":[88,208,257],"tyrosine":[89],"hydroxylase":[90],"(TH)-immunoreactivity,":[91],"were":[92,164,206],"observed":[93],"widely":[94],"throughout":[95],"brain":[97],"Indian":[100],"major":[101],"carp,":[102],"Cirrhinus":[103],"cirrhosus.":[104],"The":[105,150,170,277],"granule":[106],"and":[108,118,123,143,163,183,194,281,283],"ganglion":[109],"terminal":[112],"nerve":[113],"olfactory":[116],"bulb,":[117],"ventral":[121],"telencephalon":[122],"preoptic":[124],"area":[125],"(POA)":[126],"showed":[127,147,157],"conspicuous":[128],"TH":[129,153,202,235],"immunoreactivity.":[130],"In":[131],"POA,":[133],"nucleus":[135],"preopticus":[136],"periventricularis":[137],"(NPP),":[138],"divisible":[139],"into":[140],"anterior":[141],"(NPPa)":[142],"posterior":[144],"(NPPp)":[145],"components,":[146],"prominent":[148],"TH-immunoreactivity.":[149],"majority":[151],"neurones":[154,203,236,260],"NPPa":[156,171,205,238,262,287],"axonal":[158],"extensions":[159],"to":[160,174,242,269],"closely":[165],"associated":[166],"with":[167,215],"also":[172],"appeared":[173],"be":[175,289],"site":[177],"intense":[179],"between":[181],"because":[185],"it":[186],"contains":[187],"a":[188,216,225,290],"rich":[189],"network":[190],"fibres":[193],"few":[195],"immunoreactive":[196],"Approximately":[198],"89.7":[199],"\u00b1":[200],"1.5%":[201],"contacted":[207],"fibres.":[210],"Superfused":[211],"POA":[212],"slices":[213],"treated":[214],"Y2":[218,264],"-receptor":[219,245],"agonist,":[220,246],"13-36":[222],"resulted":[223],"significant":[226],"(P":[227],"<":[228],"0.001)":[229],"TH-immunoreactivity":[232],"NPPa.":[234],"did":[239],"respond":[241],"Y1":[244],"[Leu(31)":[247],",":[248],"Pro(34)":[249],"]":[250],"treatment.":[253],"We":[254],"suggest":[255],"that,":[256],"inhibiting":[258],"DAergic":[259],"-receptors,":[265],"may":[267],"contribute":[268],"up-regulation":[271],"GnRH-LH":[274],"axis.":[276],"microcircuitry":[278],"their":[284],"might":[288],"crucial":[291],"component":[292],"central":[295]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}