{"id":"https://openalex.org/W2059963660","doi":"https://doi.org/10.1016/s0968-0004(03)00062-8","title":"Amidase domains from bacterial and phage autolysins define a family of \u03b3-d,l-glutamate-specific amidohydrolases","display_name":"Amidase domains from bacterial and phage autolysins define a family of \u03b3-d,l-glutamate-specific amidohydrolases","publication_year":2003,"publication_date":"2003-05-01","ids":{"openalex":"https://openalex.org/W2059963660","doi":"https://doi.org/10.1016/s0968-0004(03)00062-8","mag":"2059963660","pmid":"https://pubmed.ncbi.nlm.nih.gov/12765833"},"language":"en","primary_location":{"id":"doi:10.1016/s0968-0004(03)00062-8","doi":"https://doi.org/10.1016/s0968-0004(03)00062-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0968-0004(03)00062-8","pdf_url":null,"source":{"id":"https://openalex.org/S136233269","display_name":"Trends in Biochemical Sciences","issn_l":"0968-0004","issn":["0968-0004","1362-4326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Biochemical Sciences","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009636964","display_name":"Daniel John Rigden","orcid":"https://orcid.org/0000-0002-7565-8937","observed_orcids":["https://orcid.org/0000-0002-7565-8937"]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405284811","display_name":"Embrapa Recursos Gen\u00e9ticos e Biotecnologia","ror":"https://ror.org/047y8rp84","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405284811"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Daniel J. Rigden","raw_affiliation_strings":["National Center of Genetic Resources and Biotechnology, Cenargen/Embrapa, Bras\u00edlia, D.F. 70770-900, Brazil. daniel@cenargen.embrapa.br","National Center of Genetic Resources and Biotechnology, Cenargen/Embrapa, Brasilia D.F. 70770\u2010900, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center of Genetic Resources and Biotechnology, Cenargen/Embrapa, Bras\u00edlia, D.F. 70770-900, Brazil. daniel@cenargen.embrapa.br","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284811"]},{"raw_affiliation_string":"National Center of Genetic Resources and Biotechnology, Cenargen/Embrapa, Brasilia D.F. 70770\u2010900, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284811"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110221615","display_name":"Mark J. Jedrzejas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark J. Jedrzejas","raw_affiliation_strings":["Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077552473","display_name":"Michael Y. Galperin","orcid":"https://orcid.org/0000-0002-2265-5572","observed_orcids":["https://orcid.org/0000-0002-2265-5572"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Y. Galperin","raw_affiliation_strings":["National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5009636964"],"corresponding_institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284811"],"apc_list":{"value":7030,"currency":"USD","value_usd":7030},"apc_paid":null,"fwci":1.1844,"has_fulltext":false,"cited_by_count":157,"citation_normalized_percentile":{"value":0.73195876,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":100},"biblio":{"volume":"28","issue":"5","first_page":"230","last_page":"234"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.8159000277519226,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.8159000277519226,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.07840000092983246,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.03689999878406525,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-acetylmuramoyl-l-alanine-amidase","display_name":"N-acetylmuramoyl-L-alanine amidase","score":0.8650000095367432},{"id":"https://openalex.org/keywords/peptidoglycan-hydrolase","display_name":"peptidoglycan hydrolase","score":0.9279999732971191},{"id":"https://openalex.org/keywords/bacterial-surface-antigens","display_name":"bacterial surface antigens","score":0.8330000042915344},{"id":"https://openalex.org/keywords/vaccine-targets","display_name":"vaccine targets","score":0.5239999890327454},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.8830000162124634}],"concepts":[{"id":"https://openalex.org/C65588867","wikidata":"https://www.wikidata.org/wiki/Q24775735","display_name":"Amidase","level":3,"score":0.8364039659500122},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4806462824344635},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.46720239520072937},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3744276762008667},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3374687433242798},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.33570465445518494},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15993362665176392},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000581","descriptor_name":"Amidohydrolases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000581","descriptor_name":"Amidohydrolases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009238","descriptor_name":"N-Acetylmuramoyl-L-alanine Amidase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0968-0004(03)00062-8","doi":"https://doi.org/10.1016/s0968-0004(03)00062-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0968-0004(03)00062-8","pdf_url":null,"source":{"id":"https://openalex.org/S136233269","display_name":"Trends in Biochemical Sciences","issn_l":"0968-0004","issn":["0968-0004","1362-4326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Biochemical Sciences","raw_type":"journal-article"},{"id":"pmid:12765833","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12765833","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in biochemical sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3891165741","display_name":"STRUCTURAL STUDIES OF BACTERIAL HYALURONATE LYASE ENZYME","funder_award_id":"R01AI044079","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332180","display_name":"Defense Advanced Research Projects Agency","ror":"https://ror.org/02caytj08"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1970191667","https://openalex.org/W1973702400","https://openalex.org/W1983728410","https://openalex.org/W2032810393","https://openalex.org/W2043587098","https://openalex.org/W2046439293","https://openalex.org/W2047112721","https://openalex.org/W2054683843","https://openalex.org/W2059775525","https://openalex.org/W2065826271","https://openalex.org/W2069676127","https://openalex.org/W2079572727","https://openalex.org/W2081678753","https://openalex.org/W2085277871","https://openalex.org/W2088749908","https://openalex.org/W2092885055","https://openalex.org/W2113183492","https://openalex.org/W2113539024","https://openalex.org/W2115127030","https://openalex.org/W2120242788","https://openalex.org/W2125342594","https://openalex.org/W2133790733","https://openalex.org/W2136215319","https://openalex.org/W2141212142","https://openalex.org/W2141885858","https://openalex.org/W2143199763","https://openalex.org/W2153187042","https://openalex.org/W2160216877","https://openalex.org/W2163181687","https://openalex.org/W2169950761","https://openalex.org/W2171091522","https://openalex.org/W2172053047","https://openalex.org/W2765633603"],"related_works":["https://openalex.org/W2047112721","https://openalex.org/W2740802837","https://openalex.org/W2128963064","https://openalex.org/W1989552560","https://openalex.org/W7096843043","https://openalex.org/W2113646257","https://openalex.org/W1514295653","https://openalex.org/W1992310238","https://openalex.org/W7083345382","https://openalex.org/W2069676127"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":16}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
