{"id":"https://openalex.org/W2059957409","doi":"https://doi.org/10.1117/12.884619","title":"A distributed national network for label-free rapid identification of emerging pathogens","display_name":"A distributed national network for label-free rapid identification of emerging pathogens","publication_year":2011,"publication_date":"2011-05-13","ids":{"openalex":"https://openalex.org/W2059957409","doi":"https://doi.org/10.1117/12.884619","mag":"2059957409"},"language":"en","primary_location":{"id":"doi:10.1117/12.884619","doi":"https://doi.org/10.1117/12.884619","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.884619","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053912700","display_name":"Joseph Paul Robinson","orcid":"https://orcid.org/0000-0001-8383-3240","observed_orcids":["https://orcid.org/0000-0001-8383-3240"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Paul Robinson","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034713503","display_name":"Bartek P. Rajwa","orcid":"https://orcid.org/0000-0001-7540-8236","observed_orcids":["https://orcid.org/0000-0001-7540-8236"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bartek P. Rajwa","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067612292","display_name":"Murat D\u00fcndar","orcid":"https://orcid.org/0000-0001-5752-468X","observed_orcids":["https://orcid.org/0000-0001-5752-468X","https://orcid.org/0000-0002-3956-8088"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Murat Dundar","raw_affiliation_strings":["Indiana Univ.-Purdue Univ. Indianapolis (USA)","Indiana University-Purdue University Indianapolis, United States#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana Univ.-Purdue Univ. Indianapolis (USA)","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I55769427"]},{"raw_affiliation_string":"Indiana University-Purdue University Indianapolis, United States#TAB#","institution_ids":["https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041737084","display_name":"Euiwon Bae","orcid":"https://orcid.org/0000-0001-6095-3223","observed_orcids":["https://orcid.org/0000-0001-6095-3223"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Euiwon Bae","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026115858","display_name":"Valery Patsekin","orcid":"https://orcid.org/0000-0001-9314-2582","observed_orcids":["https://orcid.org/0000-0001-9314-2582"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Valery Patsekin","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112762833","display_name":"E. Daniel Hirleman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. Daniel Hirleman","raw_affiliation_strings":["Univ. of California, Merced (USA)","University of California, Merced (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of California, Merced (USA)","institution_ids":["https://openalex.org/I156087764"]},{"raw_affiliation_string":"University of California, Merced (United States)","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031774178","display_name":"Ali M. Roumani","orcid":"https://orcid.org/0000-0003-1840-9712","observed_orcids":["https://orcid.org/0000-0003-1840-9712"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ali Roumani","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052873020","display_name":"Arun K. Bhunia","orcid":"https://orcid.org/0000-0003-3640-1554","observed_orcids":["https://orcid.org/0000-0003-3640-1554"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arun K. Bhunia","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048693490","display_name":"J. Eric Dietz","orcid":"https://orcid.org/0000-0001-5418-3824","observed_orcids":["https://orcid.org/0000-0001-5418-3824"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Eric Dietz","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060881837","display_name":"Vincent Jo Davisson","orcid":"https://orcid.org/0000-0003-1182-0007","observed_orcids":["https://orcid.org/0000-0003-1182-0007"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. Jo Davisson","raw_affiliation_strings":["Purdue Univ. (USA)","#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue Univ. (USA)","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Purdue University, United States#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113489239","display_name":"John G. Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12097938","display_name":"West Virginia University","ror":"https://ror.org/011vxgd24","country_code":"US","type":"education","lineage":["https://openalex.org/I12097938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John G. Thomas","raw_affiliation_strings":["West Virginia Univ. (USA)","West Virginia University, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"West Virginia Univ. (USA)","institution_ids":["https://openalex.org/I12097938"]},{"raw_affiliation_string":"West Virginia University, United States","institution_ids":["https://openalex.org/I12097938"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.986,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.74762658,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"8018","issue":null,"first_page":"80180C","last_page":"80180C"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioterrorism-detection","display_name":"bioterrorism detection","score":0.7630000114440918},{"id":"https://openalex.org/keywords/emerging-pathogens","display_name":"emerging pathogens","score":0.921999990940094},{"id":"https://openalex.org/keywords/label-free-detection","display_name":"label-free detection","score":0.8149999976158142},{"id":"https://openalex.org/keywords/elastic-light-scattering","display_name":"elastic light scattering","score":0.9800000190734863},{"id":"https://openalex.org/keywords/raman-spectroscopy","display_name":"Raman spectroscopy","score":0.9599999785423279},{"id":"https://openalex.org/keywords/phenotypic-identification","display_name":"phenotypic identification","score":0.6290000081062317},{"id":"https://openalex.org/keywords/machine-learning","display_name":"machine learning","score":0.5979999899864197},{"id":"https://openalex.org/keywords/food-and-water-contamination","display_name":"food and water contamination","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C2778545548","wikidata":"https://www.wikidata.org/wiki/Q4914739","display_name":"Biodefense","level":2,"score":0.8004354238510132},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6157518625259399},{"id":"https://openalex.org/C59411770","wikidata":"https://www.wikidata.org/wiki/Q8242560","display_name":"Biological warfare","level":2,"score":0.5622595548629761},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.49651914834976196},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.47759056091308594},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4415455460548401},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.389125257730484},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18187984824180603},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.1640445590019226},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12472215294837952},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.884619","doi":"https://doi.org/10.1117/12.884619","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.884619","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W1977970652","https://openalex.org/W2097329556","https://openalex.org/W2159149793"],"related_works":["https://openalex.org/W6960028544","https://openalex.org/W1978018172","https://openalex.org/W2078195931","https://openalex.org/W2316367001","https://openalex.org/W1581540457","https://openalex.org/W4412540485","https://openalex.org/W3116352301","https://openalex.org/W1580786288","https://openalex.org/W3010668403","https://openalex.org/W1979366431"],"abstract_inverted_index":{"Typical":[0],"bioterrorism":[1],"prevention":[2],"scenarios":[3],"assume":[4],"well-known":[5],"and":[6,43,60,65,200],"well-characterized":[7],"pathogens":[8,95],"like":[9],"anthrax":[10],"or":[11,25,115,224],"tularemia,":[12],"which":[13],"are":[14,105],"serious":[15],"public":[16],"concerns":[17],"if":[18],"released":[19],"into":[20,90],"food":[21],"and/or":[22,161],"water":[23],"supplies":[24],"distributed":[26],"using":[27,126,193],"other":[28],"vectors.":[29],"Common":[30,84],"governmental":[31],"contingencies":[32],"include":[33],"rapid":[34],"response":[35],"to":[36,100,136,208],"these":[37,180],"biological":[38],"threats":[39],"with":[40,172],"predefined":[41],"treatments":[42],"management":[44],"operations.":[45],"However,":[46],"bioterrorist":[47],"attacks":[48],"may":[49],"follow":[50],"a":[51,124,139,146,173,194],"far":[52],"more":[53],"sophisticated":[54],"route.":[55],"With":[56],"the":[57,66,73,109,119,209,213],"widely":[58],"known":[59,113],"immense":[61],"progress":[62],"in":[63],"genetics":[64],"availability":[67],"of":[68,78,111,121,149,168,191,197,202,205,212],"molecular":[69],"biology":[70],"tools":[71],"worldwide,":[72],"potential":[74],"for":[75,176],"malicious":[76],"modification":[77],"pathogenic":[79],"genomes":[80],"is":[81,217],"very":[82],"high.":[83],"non-pathogenic":[85],"microorganisms":[86],"could":[87,96],"be":[88,98,134],"transformed":[89],"dangerous,":[91],"debilitating":[92],"pathogens.":[93,206],"Known":[94],"also":[97],"modified":[99,140],"avoid":[101],"detection,":[102],"because":[103],"organisms":[104],"traditionally":[106],"identified":[107],"on":[108,152],"basis":[110],"their":[112],"physiological":[114],"genetic":[116,127,166],"properties.":[117],"In":[118],"absence":[120],"defined":[122],"primers":[123],"laboratory":[125],"biodetection":[128],"methods":[129],"such":[130],"as":[131,155],"PCR":[132],"might":[133],"unable":[135],"quickly":[137],"identify":[138],"microorganism.":[141],"Our":[142],"concept":[143],"includes":[144],"developing":[145],"nationwide":[147],"database":[148],"signatures":[150],"based":[151],"biophysical":[153,203],"(such":[154],"elastic":[156],"light":[157],"scattering":[158],"(ELS)":[159],"properties":[160,167],"Raman":[162],"spectra)":[163],"rather":[164],"than":[165,221],"bacteria.":[169],"When":[170],"paired":[171],"machine-learning":[174],"system":[175],"emerging":[177],"pathogen":[178],"detection":[179,185,214],"data":[181],"become":[182],"an":[183],"effective":[184],"system.":[186],"The":[187],"approach":[188],"emphasizes":[189],"ease":[190],"implementation":[192],"standardized":[195],"collection":[196],"phenotypic":[198],"information":[199],"extraction":[201],"features":[204],"Owing":[207],"label-free":[210],"nature":[211],"modalities":[215],"ELS":[216],"significantly":[218],"less":[219],"costly":[220],"any":[222],"genotypic":[223],"mass":[225],"spectrometry":[226],"approach.":[227]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}